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Does Damage to DNA and Other Macromolecules Play a Role in Aging? If So, How?
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2009, v. 64A, n. 2, p. 175, doi. 10.1093/gerona/gln065
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- Article
Does damage to DNA and other macromolecules play a role in aging? If so, how?
- Published in:
- 2009
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- Publication type:
- journal article
A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations.
- Published in:
- Frontiers in Genetics, 2021, v. 11, p. 1, doi. 10.3389/fgene.2021.680560
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- Article
SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing.
- Published in:
- Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.505441
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- Article
The Future of Human Longevity: Time for a Reality Check.
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- 2017
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- Publication type:
- journal article
Aging and the Inevitable Limit to Human Life Span.
- Published in:
- 2017
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- Publication type:
- journal article
The Essence of Aging.
- Published in:
- 2016
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- Publication type:
- journal article
Aging alters the apoptotic response to genotoxic stress.
- Published in:
- Nature Medicine, 2002, v. 8, n. 1, p. 3, doi. 10.1038/nm0102-3
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- Publication type:
- Article
The Dynamics of Genome Organization and Expression during the Aging Process.
- Published in:
- Annals of the New York Academy of Sciences, 1992, v. 673, n. 1, p. 58, doi. 10.1111/j.1749-6632.1992.tb27437.x
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- Article
Transgenic Mice and Age-Related Mutations.
- Published in:
- Annals of the New York Academy of Sciences, 1992, v. 663, n. 1, p. 26, doi. 10.1111/j.1749-6632.1992.tb38645.x
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- Article
DNA Processing, Aging, and Cancer.
- Published in:
- Annals of the New York Academy of Sciences, 1991, v. 621, n. 1, p. 53, doi. 10.1111/j.1749-6632.1991.tb16968.x
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- Article
Time, tumours and telomeres: Meeting on Cancer and Aging.
- Published in:
- EMBO Reports, 2006, v. 7, n. 5, p. 479, doi. 10.1038/sj.embor.7400680
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- Publication type:
- Article
Single-cell, locus-specific bisulfite sequencing (SLBS) for direct detection of epimutations in DNA methylation patterns.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 14, p. 1, doi. 10.1093/nar/gkv366
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- Publication type:
- Article
Direct, genome-wide assessment of DNA mutations in single cells.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 5, p. 2032, doi. 10.1093/nar/gkr949
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- Publication type:
- Article
New Insights into Bioactive Compounds of Traditional Chinese Medicines for Insulin Resistance Based on Signaling Pathways.
- Published in:
- Chemistry & Biodiversity, 2019, v. 16, n. 9, p. N.PAG, doi. 10.1002/cbdv.201900176
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- Publication type:
- Article
That obscure object of desire.
- Published in:
- 2011
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- Publication type:
- Book Review
Mitochondrial DNA mutations and aging: a case closed?
- Published in:
- Nature Genetics, 2007, v. 39, n. 4, p. 445, doi. 10.1038/ng0407-445
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- Article
Surviving aging.
- Published in:
- Nature Genetics, 2003, v. 34, n. 3, p. 237, doi. 10.1038/ng0703-237
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- Article
A model system for analyzing somatic mutations in Drosophila melanogaster.
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- Nature Methods, 2007, v. 4, n. 5, p. 401, doi. 10.1038/nmeth1027
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- Article
Chromosome instability and aneuploidy in the mammalian brain.
- Published in:
- Chromosome Research, 2023, v. 31, n. 4, p. 1, doi. 10.1007/s10577-023-09740-w
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- Publication type:
- Article
Turning anti-ageing genes against cancer.
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- Nature Reviews Molecular Cell Biology, 2008, v. 9, n. 11, p. 903, doi. 10.1038/nrm2526
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- Article
Whole Chromosome Instability induces senescence and promotes SASP.
- Published in:
- Scientific Reports, 2016, p. 35218, doi. 10.1038/srep35218
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- Publication type:
- Article
Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133742
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- Publication type:
- Article
The Progeroid Phenotype of Ku80 Deficiency Is Dominant over DNA-PK<sub>CS</sub> Deficiency.
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- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093568
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- Publication type:
- Article
Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086358
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- Publication type:
- Article
Myc-Dependent Genome Instability and Lifespan in <i>Drosophila</i>.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074641
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- Publication type:
- Article
High Preservation of CpG Cytosine Methylation Patterns at Imprinted Gene Loci in Liver and Brain of Aged Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073496
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- Publication type:
- Article
Effect of Ku80 Deficiency on Mutation Frequencies and Spectra at a LacZ Reporter Locus in Mouse Tissues and Cells.
- Published in:
- PLoS ONE, 2008, v. 3, n. 10, p. 1, doi. 10.1371/journal.pone.0003458
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- Publication type:
- Article
Homeostatic Imbalance between Apoptosis and Cell Renewal in the Liver of Premature Aging Xpd<sup>TTD</sup> Mice.
- Published in:
- PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002346
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- Publication type:
- Article
Aging: A Genetic Balancing Act.
- Published in:
- 2007
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- Publication type:
- Editorial
Aging and Genome Maintenance.
- Published in:
- Annals of the New York Academy of Sciences, 2005, v. 1055, n. 1, p. 35, doi. 10.1196/annals.1323.007
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- Publication type:
- Article
BRCA1 Gene Sequence Variation in Centenarians.
- Published in:
- Annals of the New York Academy of Sciences, 2001, v. 928, n. 1, p. 85, doi. 10.1111/j.1749-6632.2001.tb05639.x
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- Publication type:
- Article
Comparative genetics of longevity and cancer: insights from long-lived rodents.
- Published in:
- Nature Reviews Genetics, 2014, v. 15, n. 8, p. 531, doi. 10.1038/nrg3728
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- Article
MPHASYS: a mouse phenotype analysis system.
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- BMC Bioinformatics, 2007, v. 8, p. 183, doi. 10.1186/1471-2105-8-183
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- Publication type:
- Article
Two-dimensional gene scanning: Exploring human genetic variability.
- Published in:
- Electrophoresis, 1999, v. 20, n. 6, p. 1239, doi. 10.1002/(SICI)1522-2683(19990101)20:6<1239::AID-ELPS1239>3.0.CO;2-T
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- Publication type:
- Article
Genome scanning by two-dimensional DNA typing: The use of repetitive DNA sequences for rapid mapping of genetic traits.
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- Electrophoresis, 1991, v. 12, n. 2/3, p. 119, doi. 10.1002/elps.1150120206
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- Article
Denaturing gradient gel electrophoretic analysis of minisatellite alleles.
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- Electrophoresis, 1991, v. 12, n. 1, p. 12, doi. 10.1002/elps.1150120104
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- Publication type:
- Article
Epigenetic factors in aging and longevity.
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- Pflügers Archiv: European Journal of Physiology, 2010, v. 459, n. 2, p. 247, doi. 10.1007/s00424-009-0730-7
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- Article
Puzzles, promises and a cure for ageing.
- Published in:
- Nature, 2008, v. 454, n. 7208, p. 1065, doi. 10.1038/nature07216
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- Publication type:
- Article
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
- Published in:
- Nature, 2006, v. 444, n. 7122, p. 1038, doi. 10.1038/nature05456
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- Publication type:
- Article
Increased cell-to-cell variation in gene expression in ageing mouse heart.
- Published in:
- Nature, 2006, v. 441, n. 7096, p. 1011, doi. 10.1038/nature04844
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- Article
Ageing: Chromatin unbound.
- Published in:
- Nature, 2006, v. 440, n. 7086, p. 874, doi. 10.1038/440874a
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- Article
Somatic mutations in aging and disease.
- Published in:
- GeroScience, 2024, v. 46, n. 5, p. 5171, doi. 10.1007/s11357-024-01113-3
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- Article
Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span.
- Published in:
- GeroScience, 2021, v. 43, n. 5, p. 2167, doi. 10.1007/s11357-021-00428-9
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- Publication type:
- Article
Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways.
- Published in:
- GeroScience, 2020, v. 42, n. 4, p. 1119, doi. 10.1007/s11357-020-00214-z
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- Publication type:
- Article
Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice
- Published in:
- American Journal of Hypertension, 2003, v. 16, n. 1, p. 1, doi. 10.1016/S0895-7061(02)03086-8
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- Publication type:
- Article
A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46606-w
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- Publication type:
- Article
DNA damage and ageing: new-age ideas for an age-old problem.
- Published in:
- Nature Cell Biology, 2008, v. 10, n. 11, p. 1241, doi. 10.1038/ncb1108-1241
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- Publication type:
- Article
Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours.
- Published in:
- Oncogene, 2000, v. 19, n. 16, p. 2060, doi. 10.1038/sj.onc.1203537
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- Publication type:
- Article
Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA.
- Published in:
- Oncogene, 1999, v. 18, n. 5, p. 1257, doi. 10.1038/sj.onc.1202404
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- Publication type:
- Article