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A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models.
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- Pharmaceutical Statistics, 2013, v. 12, n. 3, p. 129, doi. 10.1002/pst.1561
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- Article
Clinical trial simulation of docetaxel in patients with cancer as a tool for dosage optimization.
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- Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 6, p. 677, doi. 10.1067/mcp.2000.111948
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- Article
Accelerating diagnosis of Parkinson's disease through risk prediction.
- Published in:
- 2021
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- journal article
Using the SAEM algorithm for mechanistic joint models characterizing the relationship between nonlinear PSA kinetics and survival in prostate cancer patients.
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- Biometrics, 2017, v. 73, n. 1, p. 305, doi. 10.1111/biom.12537
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- Article
Evaluation of bootstrap methods for estimating uncertainty of parameters in nonlinear mixed-effects models: a simulation study in population pharmacokinetics.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 1, p. 15, doi. 10.1007/s10928-013-9343-z
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- Article
Optimizing pharmacokinetic bridging studies in paediatric oncology using physiologically-based pharmacokinetic modelling: application to docetaxel.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 3, p. 534, doi. 10.1111/bcp.12702
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- Article
A mechanism-based model for the population pharmacokinetics of free and bound aflibercept in healthy subjects.
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- British Journal of Clinical Pharmacology, 2011, v. 72, n. 3, p. 402, doi. 10.1111/j.1365-2125.2011.04015.x
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- Article
Population pharmacokinetics and pharmacodynamics of enoxaparin in unstable angina and non-ST-segment elevation myocardial infarction.
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- British Journal of Clinical Pharmacology, 2003, v. 56, n. 4, p. 407, doi. 10.1046/j.1365-2125.2003.01904.x
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- Article
Bayesian Individual Dynamic Predictions with Uncertainty of Longitudinal Biomarkers and Risks of Survival Events in a Joint Modelling Framework: a Comparison Between Stan, Monolix, and NONMEM.
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- AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-019-0388-9
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- Article
Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches.
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- AAPS Journal, 2015, v. 17, n. 3, p. 691, doi. 10.1208/s12248-015-9745-5
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- Article
Joint modelling and simulation of M‐protein dynamics and progression‐free survival for alternative isatuximab dosing with pomalidomide/dexamethasone.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 5, p. 2052, doi. 10.1111/bcp.15123
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- Article
Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer.
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- 2017
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- Publication type:
- journal article
International randomized phase 2 study on the addition of docetaxel to the combination of cisplatin and 5-fluorouracil in the induction treatment for nasopharyngeal carcinoma in children and adolescents.
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- 2016
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- Publication type:
- journal article
Population pharmacokinetic analysis of free and bound aflibercept in patients with advanced solid tumors.
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- Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 1, p. 167, doi. 10.1007/s00280-013-2182-1
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- Article
Joint modeling of tumor dynamics and progression‐free survival in advanced breast cancer: Leveraging data from amcenestrant early phase I–II trials.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 941, doi. 10.1002/psp4.13128
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- Article
Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 1846, doi. 10.1002/psp4.12947
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- Article
Exposure‐response analyses for selection/confirmation of optimal isatuximab dosing regimen in combination with pomalidomide/dexamethasone treatment in patients with multiple myeloma.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 6, p. 766, doi. 10.1002/psp4.12789
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- Article
PK/PD modeling analysis for dosing regimen selection of isatuximab as single agent and in combination therapy in patients with multiple myeloma.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 8, p. 928, doi. 10.1002/psp4.12666
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- Article
Translational Model-Based Strategy to Guide the Choice of Clinical Doses for Antibody-Drug Conjugates.
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- Journal of Clinical Pharmacology, 2017, v. 57, n. 7, p. 865, doi. 10.1002/jcph.869
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- Article