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PAI-1 activity, but not fibrinogen or von Willebrand factor, is inversely related to LDL particle size in type 2 diabetes.
Published in:
Diabetes/Metabolism Research & Reviews, 2008, v. 24, n. 2, p. 141, doi. 10.1002/dmrr.779
By:
- Mertens, Ilse;
- Lemieux, Isabelle;
- Verrijken, An;
- Després, Jean-Pierre;
- Van Gaal, Luc F.
Publication type:
Article
Association of 1-deoxy-sphingolipids with steatosis but not steatohepatitis nor fibrosis in non-alcoholic fatty liver disease.
Published in:
Acta Diabetologica, 2021, v. 58, n. 3, p. 319, doi. 10.1007/s00592-020-01612-7
By:
- Weyler, J.;
- Verrijken, A.;
- Hornemann, T.;
- Vonghia, L.;
- Dirinck, E.;
- von Eckardstein, A.;
- Vanwolleghem, T.;
- Michielsen, P.;
- Peiffer, F.;
- Driessen, A.;
- Hubens, G.;
- Staels, B.;
- Francque, S.;
- Van Gaal, L.
Publication type:
Article
Common variants in the gene for the serotonin receptor 6 ( HTR6) do not contribute to obesity.
Published in:
Journal of Genetics, 2010, v. 89, n. 4, p. 469, doi. 10.1007/s12041-010-0066-2
By:
- Peeters, Armand;
- Beckers, Sigri;
- Verrijken, An;
- Roevens, Peter;
- Peeters, Pieter;
- Gaal, Luc;
- Hul, Wim
Publication type:
Article
Plasma BCAA Changes in Patients With NAFLD Are Sex Dependent.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 7, p. 2311, doi. 10.1210/clinem/dgaa175
By:
- Grzych, Guillaume;
- Vonghia, Luisa;
- Bout, Marie-Adélaïde;
- Weyler, Jonas;
- Verrijken, An;
- Dirinck, Eveline;
- Chevalier Curt, Marie Joncquel;
- Gaal, Luc Van;
- Paumelle, Réjane;
- Francque, Sven;
- Tailleux, Anne;
- Haas, Joel T.;
- Staels, Bart
Publication type:
Article
Plasma BCAA Changes in Patients With NAFLD Are Sex Dependent.
Published in:
2020
By:
- Grzych, Guillaume;
- Vonghia, Luisa;
- Bout, Marie-Adélaïde;
- Weyler, Jonas;
- Verrijken, An;
- Dirinck, Eveline;
- Joncquel, Marie;
- Van Gaal, Luc;
- Paumelle, Réjane;
- Francque, Sven;
- Tailleux, Anne;
- Haas, Joel T;
- Staels, Bart;
- Chevalier Curt, Marie Joncquel
Publication type:
journal article
Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.
Published in:
2017
By:
- Legry, Vanessa;
- Francque, Sven;
- Haas, Joel T;
- Verrijken, An;
- Caron, Sandrine;
- Chávez-Talavera, Oscar;
- Vallez, Emmanuelle;
- Vonghia, Luisa;
- Dirinck, Eveline;
- Verhaegen, Ann;
- Kouach, Mostafa;
- Lestavel, Sophie;
- Lefebvre, Philippe;
- Van Gaal, Luc;
- Tailleux, Anne;
- Paumelle, Réjane;
- Staels, Bart
Publication type:
journal article
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids.
Published in:
Diabetologia, 2013, v. 56, n. 10, p. 2266, doi. 10.1007/s00125-013-2981-2
By:
- Orešič, Matej;
- Hyötyläinen, Tuulia;
- Kotronen, Anna;
- Gopalacharyulu, Peddinti;
- Nygren, Heli;
- Arola, Johanna;
- Castillo, Sandra;
- Mattila, Ismo;
- Hakkarainen, Antti;
- Borra, Ronald;
- Honka, Miikka-Juhani;
- Verrijken, An;
- Francque, Sven;
- Iozzo, Patricia;
- Leivonen, Marja;
- Jaser, Nabil;
- Juuti, Anne;
- Sørensen, Thorkild;
- Nuutila, Pirjo;
- Gaal, Luc
Publication type:
Article
Features of oral glucose tolerance tests in patients after Roux-en-Y gastric bypass with and without hypoglycaemia symptoms in daily life: It's all about speed.
Published in:
Diabetes, Obesity & Metabolism, 2020, v. 22, n. 11, p. 2107, doi. 10.1111/dom.14130
By:
- Mariën, Ilke;
- De Block, Christophe;
- Verrijken, An;
- Van Dessel, Kristof;
- Peiffer, Frida;
- Verhaegen, Ann;
- Hubens, Guy;
- Van Gaal, Luc;
- Dirinck, Eveline
Publication type:
Article
Effect of Long-Term Whole Body Vibration Training on Visceral Adipose Tissue: A Preliminary Report.
Published in:
Obesity Facts: The European Journal of Obesity, 2010, v. 3, n. 2, p. 93, doi. 10.1159/000301785
By:
- Vissers, Dirk;
- Verrijken, An;
- Mertens, Ilse;
- Van Gils, Caroline;
- Van de Sompel, Annemie;
- Truijen, Steven;
- Van Gaal, Luc
Publication type:
Article
Peripheral and Hepatic Vein Cytokine Levels in Correlation with Non-Alcoholic Fatty Liver Disease (NAFLD)-Related Metabolic, Histological, and Haemodynamic Features.
Published in:
PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0143380
By:
- Vonghia, Luisa;
- Magrone, Thea;
- Verrijken, An;
- Michielsen, Peter;
- Van Gaal, Luc;
- Jirillo, Emilio;
- Francque, Sven
Publication type:
Article
Glucose Intolerance and the Amount of Visceral Adipose Tissue Contribute to an Increase in Circulating Triglyceride Concentrations in Caucasian Obese Females.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045145
By:
- Berings, Margot;
- Wehlou, Charline;
- Verrijken, An;
- Deschepper, Ellen;
- Mertens, Ilse;
- Kaufman, Jean-Marc;
- Van Gaal, Luc F.;
- Ouwens, D. Margriet;
- Ruige, Johannes B.;
- Atkin, Stephen L.
Publication type:
Article
Association of SIRT1 gene variation with visceral obesity.
Published in:
Human Genetics, 2008, v. 124, n. 4, p. 431, doi. 10.1007/s00439-008-0567-8
By:
- Peeters, Armand V.;
- Beckers, Sigri;
- Verrijken, An;
- Mertens, Ilse;
- Roevens, Peter;
- Peeters, Pieter J.;
- Van Hul, Wim;
- Van Gaal, Luc F.
Publication type:
Article
Screening for genetic variants in BDNF that contribute to childhood obesity.
Published in:
Pediatric Obesity, 2014, v. 9, n. 1, p. 36, doi. 10.1111/j.2047-6310.2012.00131.x
By:
- Zegers, D.;
- Hendrickx, R.;
- Verrijken, A.;
- Van Hoorenbeeck, K.;
- Van Camp, J. K.;
- Craemer, V.;
- Rooman, R. P.;
- Desager, K. N.;
- Massa, G.;
- Van Gaal, L. F.;
- Van Hul, W.;
- Beckers, S.
Publication type:
Article
Nucleotide variation of sFRP5 gene is not associated with obesity in children and adolescents.
Published in:
Molecular Biology Reports, 2016, v. 43, n. 10, p. 1041, doi. 10.1007/s11033-016-4050-7
By:
- Van Camp, Jasmijn;
- Beckers, Sigri;
- Zegers, Doreen;
- Verhulst, Stijn;
- Van Hoorenbeeck, Kim;
- Massa, Guy;
- Verrijken, An;
- Desager, Kristine;
- Van Gaal, Luc;
- Van Hul, Wim
Publication type:
Article
No important role for genetic variation in the Chibby gene in monogenic and complex obesity.
Published in:
Molecular Biology Reports, 2013, v. 40, n. 7, p. 4491, doi. 10.1007/s11033-013-2541-3
By:
- Van Camp, Jasmijn;
- Zegers, Doreen;
- Verhulst, Stijn;
- Van Hoorenbeeck, Kim;
- Massa, Guy;
- Verrijken, An;
- Desager, Kristine;
- Van Gaal, Luc;
- Van Hul, Wim;
- Beckers, Sigri
Publication type:
Article
Mutation screen of the SIM1 gene in pediatric patients with early-onset obesity.
Published in:
International Journal of Obesity, 2014, v. 38, n. 7, p. 1000, doi. 10.1038/ijo.2013.188
By:
- Zegers, D;
- Beckers, S;
- Hendrickx, R;
- Van Camp, J K;
- de Craemer, V;
- Verrijken, A;
- Van Hoorenbeeck, K;
- Verhulst, S L;
- Rooman, R P;
- Desager, K N;
- Massa, G;
- Van Gaal, L F;
- Van Hul, W
Publication type:
Article
Visceral adiposity and insulin resistance are independent predictors of the presence of non-cirrhotic NAFLD-related portal hypertension.
Published in:
International Journal of Obesity, 2011, v. 35, n. 2, p. 270, doi. 10.1038/ijo.2010.134
By:
- Francque, S.;
- Verrijken, A.;
- Mertens, I.;
- Hubens, G.;
- Van Marck, E.;
- Pelckmans, P.;
- Michielsen, P.;
- Van Gaal, L.
Publication type:
Article
Visceral adipose tissue and inflammation correlate with elevated liver tests in a cohort of overweight and obese patients.
Published in:
International Journal of Obesity, 2010, v. 34, n. 5, p. 899, doi. 10.1038/ijo.2010.4
By:
- Verrijken, A.;
- Francque, S.;
- Mertens, I.;
- Talloen, M.;
- Peiffer, F.;
- Van Gaal, L.
Publication type:
Article
Evaluation of a Role for NPY and NPY2R in the Pathogenesis of Obesity by Mutation and Copy Number Variation Analysis in Obese Children and Adolescents.
Published in:
Annals of Human Genetics, 2018, v. 82, n. 1, p. 1, doi. 10.1111/ahg.12211
By:
- Aerts, Evi;
- Geets, Ellen;
- Sorber, Laure;
- Beckers, Sigri;
- Verrijken, An;
- Massa, Guy;
- Van Hoorenbeeck, Kim;
- Verhulst, Stijn L.;
- Van Gaal, Luc F.;
- Van Hul, Wim
Publication type:
Article
A Case–Control Study Supports Genetic Contribution of the PON Gene Family in Obesity and Metabolic Dysfunction Associated Steatotic Liver Disease.
Published in:
Antioxidants, 2024, v. 13, n. 9, p. 1051, doi. 10.3390/antiox13091051
By:
- Van Dijck, Evelien;
- Diels, Sara;
- Fransen, Erik;
- Cremers, Tycho Canter;
- Verrijken, An;
- Dirinck, Eveline;
- Hoischen, Alexander;
- Vandeweyer, Geert;
- Vanden Berghe, Wim;
- Van Gaal, Luc;
- Francque, Sven;
- Van Hul, Wim
Publication type:
Article
A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01142-1
By:
- Diels, Sara;
- Cuypers, Bart;
- Tvarijonaviciute, Asta;
- Derudas, Bruno;
- Van Dijck, Evelien;
- Verrijken, An;
- Van Gaal, Luc F.;
- Laukens, Kris;
- Lefebvre, Philippe;
- Ceron, Jose J.;
- Francque, Sven;
- Vanden Berghe, Wim;
- Van Hul, Wim
Publication type:
Article
Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD.
Published in:
PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0166048
By:
- du Plessis, Johannie;
- Korf, Hannelie;
- van Pelt, Jos;
- Windmolders, Petra;
- Vander Elst, Ingrid;
- Verrijken, An;
- Hubens, Guy;
- Van Gaal, Luc;
- Cassiman, David;
- Nevens, Frederik;
- Francque, Sven;
- van der Merwe, Schalk
Publication type:
Article
A cross-sectional analysis of the association between testosterone and biopsy-proven non-alcoholic fatty liver disease in men with obesity.
Published in:
Endocrine (1355008X), 2023, v. 80, n. 1, p. 54, doi. 10.1007/s12020-022-03245-y
By:
- De Herdt, Carlien;
- De Block, Christophe;
- Francque, Sven;
- Verrijken, An;
- Van Dessel, Kristof;
- Van Gaal, Luc;
- Van Cauwenberghe, Jolijn;
- Dirinck, Eveline
Publication type:
Article
Investigation of common and rare genetic variation in the BAMBI genomic region in light of human obesity.
Published in:
Endocrine (1355008X), 2016, v. 52, n. 2, p. 277, doi. 10.1007/s12020-015-0778-4
By:
- Van Camp, Jasmijn;
- De Freitas, Fenna;
- Zegers, Doreen;
- Beckers, Sigri;
- Verhulst, Stijn;
- Hoorenbeeck, Kim;
- Massa, Guy;
- Verrijken, An;
- Desager, Kristine;
- Van Gaal, Luc;
- Van Hul, Wim
Publication type:
Article
Common genetic variation in sFRP5 is associated with fat distribution in men.
Published in:
Endocrine (1355008X), 2014, v. 46, n. 3, p. 477, doi. 10.1007/s12020-013-0088-7
By:
- Van Camp, J.;
- Beckers, S.;
- Zegers, D.;
- Verrijken, A.;
- Van Gaal, L.;
- Van Hul, W.
Publication type:
Article
Mutation analysis of WNT10B in obese children, adolescents and adults.
Published in:
Endocrine (1355008X), 2013, v. 44, n. 1, p. 107, doi. 10.1007/s12020-012-9824-7
By:
- Camp, Jasmijn;
- Zegers, Doreen;
- Verhulst, Stijn;
- Hoorenbeeck, Kim;
- Massa, Guy;
- Verrijken, An;
- Desager, Kristine;
- Gaal, Luc;
- Hul, Wim;
- Beckers, Sigri
Publication type:
Article
No conclusive evidence for association of polymorphisms in the adiponectin receptor 1 gene, AdipoR1, with common obesity.
Published in:
Endocrine (1355008X), 2013, v. 43, n. 1, p. 120, doi. 10.1007/s12020-012-9736-6
By:
- Beckers, S.;
- de Freitas, F.;
- Zegers, D.;
- Mertens, I.;
- Verrijken, A.;
- Van Camp, J.;
- Van Gaal, L.;
- Van Hul, W.
Publication type:
Article
Effect of growth hormone treatment on energy expenditure and its relation to first-year growth response in children.
Published in:
2019
By:
- Straetemans, Saartje;
- Schott, D. A.;
- Plasqui, Guy;
- Dotremont, Hilde;
- Gerver-Jansen, Angèle J. G. M.;
- Verrijken, An;
- Westerterp, Klaas;
- Zimmermann, Luc J. I.;
- Gerver, Willem-Jan M.
Publication type:
journal article
Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis.
Published in:
Biomedicines, 2020, v. 8, n. 12, p. 546, doi. 10.3390/biomedicines8120546
By:
- Verlinden, Wim;
- Van Mieghem, Eugénie;
- Depauw, Laura;
- Vanwolleghem, Thomas;
- Vonghia, Luisa;
- Weyler, Jonas;
- Driessen, Ann;
- Callens, Dirk;
- Roosens, Laurence;
- Dirinck, Eveline;
- Verrijken, An;
- Gaal, Luc Van;
- Francque, Sven
Publication type:
Article
Predicting type 2 diabetes mellitus: a comparison between the FINDRISC score and the metabolic syndrome.
Published in:
Diabetology & Metabolic Syndrome, 2018, v. 10, n. 1, p. 1, doi. 10.1186/s13098-018-0310-0
By:
- Meijnikman, Abraham S.;
- De Block, Christophe E. M.;
- Verrijken, An;
- Mertens, Ilse;
- Van Gaal, Luc F.
Publication type:
Article
Accurate non‐invasive diagnosis and staging of non‐alcoholic fatty liver disease using the urinary steroid metabolome.
Published in:
Alimentary Pharmacology & Therapeutics, 2020, v. 51, n. 11, p. 1188, doi. 10.1111/apt.15710
By:
- Moolla, Ahmad;
- Boer, Jasper;
- Pavlov, David;
- Amin, Amin;
- Taylor, Angela;
- Gilligan, Lorna;
- Hughes, Beverly;
- Ryan, John;
- Barnes, Eleanor;
- Hassan‐Smith, Zaki;
- Grove, Jane;
- Aithal, Guruprasad P.;
- Verrijken, An;
- Francque, Sven;
- Van Gaal, Luc;
- Armstrong, Matthew J.;
- Newsome, Phillip N.;
- Cobbold, Jeremy F.;
- Arlt, Wiebke;
- Biehl, Michael
Publication type:
Article
Screening for therapeutic trials and treatment indication in clinical practice: MACK‐3, a new blood test for the diagnosis of fibrotic NASH.
Published in:
Alimentary Pharmacology & Therapeutics, 2018, v. 47, n. 10, p. 1387, doi. 10.1111/apt.14621
By:
- Boursier, J.;
- Anty, R.;
- Vonghia, L.;
- Moal, V.;
- Vanwolleghem, T.;
- Canivet, C. M.;
- Michalak, S.;
- Bonnafous, S.;
- Michielsen, P.;
- Oberti, F.;
- Iannelli, A.;
- Van Gaal, L.;
- Patouraux, S.;
- Blanchet, O.;
- Verrijken, A.;
- Gual, P.;
- Rousselet, M.‐C.;
- Driessen, A.;
- Hunault, G.;
- Bertrais, S.
Publication type:
Article
Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review.
Published in:
Genes, 2022, v. 13, n. 10, p. N.PAG, doi. 10.3390/genes13101746
By:
- Van Dijck, Evelien;
- Beckers, Sigri;
- Diels, Sara;
- Huybrechts, Tammy;
- Verrijken, An;
- Van Hoorenbeeck, Kim;
- Verhulst, Stijn;
- Massa, Guy;
- Van Gaal, Luc;
- Van Hul, Wim
Publication type:
Article
Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects.
Published in:
PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197603
By:
- Kehoe, Kaat;
- Noels, Heidi;
- Theelen, Wendy;
- De Hert, Emilie;
- Xu, Shenguan;
- Verrijken, An;
- Arnould, Thierry;
- Fransen, Erik;
- Hermans, Nina;
- Lambeir, Anne-Marie;
- Venge, Per;
- Van Gaal, Luc;
- De Meester, Ingrid
Publication type:
Article
Possible role for ENPP1 polymorphism in obesity but not for INSIG2 and PLIN variants.
Published in:
Endocrine (1355008X), 2009, v. 36, n. 1, p. 103, doi. 10.1007/s12020-009-9194-y
By:
- Peeters, Armand;
- Beckers, Sigri;
- Verrijken, An;
- Mertens, Ilse;
- Van Gaal, Luc;
- Van Hul, Wim
Publication type:
Article
Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis.
Published in:
2014
By:
- Musso, Giovanni;
- Gambino, Roberto;
- Tabibian, James H;
- Ekstedt, Mattias;
- Kechagias, Stergios;
- Hamaguchi, Masahide;
- Hultcrantz, Rolf;
- Hagström, Hannes;
- Yoon, Seung Kew;
- Charatcharoenwitthaya, Phunchai;
- George, Jacob;
- Barrera, Francisco;
- Hafli[eth]adóttir, Svanhildur;
- Björnsson, Einar Stefan;
- Armstrong, Matthew J;
- Hopkins, Laurence J;
- Gao, Xin;
- Francque, Sven;
- Verrijken, An;
- Yilmaz, Yusuf
Publication type:
journal article
Association of Non-alcoholic Fatty Liver Disease with Chronic Kidney Disease: A Systematic Review and Meta-analysis.
Published in:
PLoS Medicine, 2014, v. 11, n. 7, p. 1, doi. 10.1371/journal.pmed.1001680
By:
- Musso, Giovanni;
- Gambino, Roberto;
- Tabibian, James H.;
- Ekstedt, Mattias;
- Kechagias, Stergios;
- Hamaguchi, Masahide;
- Hultcrantz, Rolf;
- Hagström, Hannes;
- Yoon, Seung Kew;
- Charatcharoenwitthaya, Phunchai;
- George, Jacob;
- Barrera, Francisco;
- Hafliðadóttir, Svanhildur;
- Björnsson, Einar Stefan;
- Armstrong, Matthew J.;
- Hopkins, Laurence J.;
- Gao, Xin;
- Francque, Sven;
- Verrijken, An;
- Yilmaz, Yusuf
Publication type:
Article
CNV analysis and mutation screening indicate an important role for the NPY4R gene in human obesity.
Published in:
2016
By:
- Aerts, Evi;
- Beckers, Sigri;
- Zegers, Doreen;
- Van Hoorenbeeck, Kim;
- Massa, Guy;
- Verrijken, An;
- Verhulst, Stijn L.;
- Van Gaal, Luc F.;
- Van Hul, Wim
Publication type:
journal article
SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus.
Published in:
Obesity (19307381), 2014, v. 22, n. 5, p. 1309, doi. 10.1002/oby.20682
By:
- Hassing, H. Carlijne;
- Surendran, R. Preethi;
- Derudas, Bruno;
- Verrijken, An;
- Francque, Sven M.;
- Mooij, Hans L.;
- Bernelot Moens, Sophie J.;
- Hart, Leen M.'t;
- Nijpels, Giel;
- Dekker, Jacqueline M.;
- Williams, Kevin Jon;
- Stroes, Erik S. G.;
- Van Gaal, Luc F.;
- Staels, Bart;
- Nieuwdorp, Max;
- Dallinga ‐ Thie, Geesje M.
Publication type:
Article
A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.
Published in:
Obesity (19307381), 2013, v. 21, n. 10, p. 2138, doi. 10.1002/oby.20366
By:
- Verrijken, A.;
- Beckers, S.;
- Francque, S.;
- Hilden, H.;
- Caron, S.;
- Zegers, D.;
- Ruppert, M.;
- Hubens, G.;
- Marck, E.;
- Michielsen, P.;
- Staels, B.;
- Taskinen, M.‐R.;
- Hul, W.;
- Gaal, L.
Publication type:
Article
Among inflammation and coagulation markers, PAI-1 is a true component of the metabolic syndrome.
Published in:
International Journal of Obesity, 2006, v. 30, n. 8, p. 1308, doi. 10.1038/sj.ijo.0803189
By:
- Mertens, I.;
- Verrijken, A.;
- Michiels, J. J.;
- Van der Planken, M.;
- Ruige, J. B.;
- Van Gaal, L. F.
Publication type:
Article
1836-P: Nonalcoholic Steatohepatitis (NASH) Significantly Contribute to ß-Cell Function Impairment Independently of Glucose Tolerance Status.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1836-P
By:
- VONGHIA, LUISA;
- DIRINCK, EVELINE;
- CARLI, FABRIZIA;
- VERRIJKEN, AN;
- WEYLER, JONAS;
- MICHIELSEN, PETER;
- VANWOLLEGHEM, THOMAS;
- DRIESSEN, ANN;
- GAAL, LUC VAN;
- FRANCQUE, SVEN;
- DE BLOCK, CHRISTOPHE;
- GASTALDELLI, AMALIA
Publication type:
Article

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