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Preclinical Assessment of the Combination of PSMA-Targeting Radionuclide Therapy with PARP Inhibitors for Prostate Cancer Treatment.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 8037, doi. 10.3390/ijms23148037
By:
- Ruigrok, Eline A. M.;
- Verkaik, Nicole S.;
- de Blois, Erik;
- de Ridder, Corrina;
- Stuurman, Debra;
- Roobol, Stefan J.;
- Van Gent, Dik C.;
- de Jong, Marion;
- Van Weerden, Wytske M.;
- Nonnekens, Julie
Publication type:
Article
C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6725, doi. 10.3390/ijms21186725
By:
- Inagawa, Takabumi;
- Wennink, Thomas;
- Lebbink, Joyce H. G.;
- Keijzers, Guido;
- Florea, Bogdan I.;
- Verkaik, Nicole S.;
- van Gent, Dik C.
Publication type:
Article
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
Published in:
2009
By:
- van der Burg, Mirjam;
- IJspeert, Hanna;
- Verkaik, Nicole S.;
- Turul, Tuba;
- Wiegant, Wouter W.;
- Morotomi-Yano, Keiko;
- Mari, Pierre-Olivier;
- Tezcan, Ilhan;
- Chen, David J.;
- Zdzienicka, Malgorzata Z.;
- van Dongen, Jacques J. M.;
- van Gent, Dik C.
Publication type:
journal article
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.
Published in:
2006
By:
- van der Burg, Mirjam;
- van Veelen, Lieneke R.;
- Verkaik, Nicole S.;
- Wiegant, Wouter W.;
- Hartwig, Nico G.;
- Barendregt, Barbara H.;
- Brugmans, Linda;
- Raams, Anja;
- Jaspers, Nicolaas G. J.;
- Zdzienicka, Malgorzata Z.;
- M .van Dongen, Jacques J;
- van Gent, Dik C.;
- van Dongen, Jacques J M
Publication type:
journal article
The role of DNA dependent protein kinase in synapsis of DNA ends.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 11, p. 3856, doi. 10.1093/nar/gkq308
By:
- Weterings, Eric;
- Verkaik, Nicole S.;
- Brüggenwirth, Hennie T.;
- Hoeijmakers, Jan H. J.;
- van Gent, Dik C.
Publication type:
Article
Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation.
Published in:
International Journal of Cancer, 1999, v. 80, n. 3, p. 439, doi. 10.1002/(SICI)1097-0215(19990129)80:3<439::AID-IJC17>3.0.CO;2-V
By:
- Verkaik, Nicole S.;
- Trapman, Jan;
- Romijn, Johannes C.;
- Van der Kwast, Theodorus H.;
- Van Steenbrugge, Gert J.
Publication type:
Article
An XRCC4 splice mutation associated with severe short stature, gonadal failure, and early-onset metabolic syndrome.
Published in:
2015
By:
- de Bruin, Christiaan;
- Mericq, Verónica;
- Andrew, Shayne F;
- van Duyvenvoorde, Hermine A;
- Verkaik, Nicole S;
- Losekoot, Monique;
- Porollo, Aleksey;
- Garcia, Hernán;
- Kuang, Yi;
- Hanson, Dan;
- Clayton, Peter;
- van Gent, Dik C;
- Wit, Jan M;
- Hwa, Vivian;
- Dauber, Andrew
Publication type:
journal article
Attenuated XPC Expression Is Not Associated with Impaired DNA Repair in Bladder Cancer.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0126029
By:
- Naipal, Kishan A. T.;
- Raams, Anja;
- Bruens, Serena T.;
- Brandsma, Inger;
- Verkaik, Nicole S.;
- Jaspers, Nicolaas G. J.;
- Hoeijmakers, Jan H. J.;
- van Leenders, Geert J. L. H.;
- Pothof, Joris;
- Kanaar, Roland;
- Boormans, Joost;
- van Gent, Dik C.
Publication type:
Article
Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2 -Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
Published in:
Cancers, 2024, v. 16, n. 4, p. 741, doi. 10.3390/cancers16040741
By:
- Meijer, Titia G.;
- Martens, John W. M.;
- Prager-van der Smissen, Wendy J. C.;
- Verkaik, Nicole S.;
- Beaufort, Corine M.;
- van Herk, Stanley;
- Robert-Finestra, Teresa;
- Hoogenboezem, Remco M.;
- Ruigrok-Ritstier, Kirsten;
- Paul, Maarten W.;
- Gribnau, Joost;
- Bindels, Eric M. J.;
- Kanaar, Roland;
- Jager, Agnes;
- van Gent, Dik C.;
- Hollestelle, Antoinette
Publication type:
Article
In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib.
Published in:
Cancers, 2023, v. 15, n. 3, p. 915, doi. 10.3390/cancers15030915
By:
- Feijtel, Danny;
- Reuvers, Thom G. A.;
- van Tuyll-van Serooskerken, Christine;
- de Ridder, Corrina M. A.;
- Stuurman, Debra C.;
- de Blois, Erik;
- Verkaik, Nicole S.;
- de Bruijn, Peter;
- Koolen, Stijn L. W.;
- de Jong, Marion;
- Nonnekens, Julie
Publication type:
Article
Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma.
Published in:
Cancers, 2023, v. 15, n. 2, p. 478, doi. 10.3390/cancers15020478
By:
- Capala, Marta E.;
- Pachler, Katrin S.;
- Lauwers, Iris;
- de Korte, Maarten A.;
- Verkaik, Nicole S.;
- Mast, Hetty;
- Jonker, Brend P.;
- Sewnaik, Aniel;
- Hardillo, Jose A.;
- Keereweer, Stijn;
- Monserez, Dominiek;
- Koljenovic, Senada;
- Mostert, Bianca;
- Verduijn, Gerda M.;
- Petit, Steven;
- van Gent, Dik C.
Publication type:
Article
Functional Ex Vivo Tissue-Based Chemotherapy Sensitivity Testing for Breast Cancer.
Published in:
Cancers, 2022, v. 14, n. 5, p. 1252, doi. 10.3390/cancers14051252
By:
- Ladan, Marjolijn M.;
- Meijer, Titia G.;
- Verkaik, Nicole S.;
- Komar, Zofia M.;
- van Deurzen, Carolien H. M.;
- den Bakker, Michael A.;
- Kanaar, Roland;
- van Gent, Dik C.;
- Jager, Agnes
Publication type:
Article
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.
Published in:
EMBO Journal, 2009, v. 28, n. 14, p. 2090, doi. 10.1038/emboj.2009.156
By:
- Pothof, Joris;
- Verkaik, Nicole S.;
- van IJcken, Wilfred;
- Wiemer, Erik A. C.;
- Ta, Van T. B.;
- van der Horst, Gijsbertus T. J.;
- Jaspers, Nicolaas G. J.;
- van Gent, Dik C.;
- Hoeijmakers, Jan H. J.;
- Persengiev, Stephan P.
Publication type:
Article
The role of DNA dependent protein kinase in synapsis of DNA ends.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 24, p. 7238, doi. 10.1093/nar/gkg889
By:
- Weterings, Eric;
- Verkaik, Nicole S.;
- Brüggenwirth, Hennie T.;
- Hoeijmakers, Jan H. J.;
- van Gent, Dik C.
Publication type:
Article
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells.
Published in:
Nature, 2002, v. 420, n. 6911, p. 93, doi. 10.1038/nature01125
By:
- Tauchi, Hiroshi;
- Kobayashi, Junya;
- Morishima, Ken-ichi;
- van Gent, Dik C.;
- Shiraishi, Takahiro;
- Verkaik, Nicole S.;
- vanHeems, Diana;
- Ito, Emi;
- Nakamura, Asako;
- Sonoda, Eiichiro;
- Takata, Minoru;
- Takeda, Shunichi;
- Matsuura, Shinya;
- Komatsu, Kenshi
Publication type:
Article
Proof-of-concept study linking ex vivo sensitivity testing to neoadjuvant anthracycline-based chemotherapy response in breast cancer patients.
Published in:
NPJ Breast Cancer, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41523-023-00583-6
By:
- Ladan, Marjolijn M.;
- Meijer, Titia G.;
- Verkaik, Nicole S.;
- de Monye, Cecile;
- Koppert, Linetta B.;
- Oomen-de Hoop, Esther;
- van Deurzen, Carolien H. M.;
- Kanaar, Roland;
- Nonnekens, Julie;
- van Gent, Dik C.;
- Jager, Agnes
Publication type:
Article
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo.
Published in:
Theranostics, 2023, v. 13, n. 10, p. 3117, doi. 10.7150/thno.82963
By:
- Reuvers, Thom G. A.;
- Verkaik, Nicole S.;
- Stuurman, Debra;
- de Ridder, Corrina;
- Clahsen-van Groningen, Marian C.;
- de Blois, Erik;
- Nonnekens, Julie
Publication type:
Article
Inter and intra-tumor somatostatin receptor 2 heterogeneity influences peptide receptor radionuclide therapy response.
Published in:
Theranostics, 2021, v. 11, n. 2, p. 491, doi. 10.7150/thno.51215
By:
- Feijtel, Danny;
- Doeswijk, Gabriela N.;
- Verkaik, Nicole S.;
- Haeck, Joost C.;
- Chicco, Daniela;
- Angotti, Carmelina;
- Konijnenberg, Mark W.;
- de Jong, Marion;
- Nonnekens, Julie
Publication type:
Article
Tumor slice culture system to assess drug response of primary breast cancer.
Published in:
2015
By:
- Naipal, Kishan A T;
- Verkaik, Nicole S;
- Sánchez, Humberto;
- van Deurzen, Carolien H M;
- den Bakker, Michael A;
- Hoeijmakers, Jan H J;
- Kanaar, Roland;
- Vreeswijk, Maaike P G;
- Jager, Agnes;
- van Gent, Dik C
Publication type:
journal article
Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches.
Published in:
European Journal of Immunology, 2007, v. 37, n. 12, p. 3522, doi. 10.1002/eji.200737624
By:
- van der Burg, Mirjam;
- Verkaik, Nicole S.;
- den Dekker, Alexander T.;
- Barendregt, Barbara H.;
- Pico-Knijnenburg, Ingrid;
- Tezcan, Ilhan;
- vanDongen, Jacques J. M.;
- van Gent, Dik C.
Publication type:
Article
Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.
Published in:
European Journal of Immunology, 2002, v. 32, n. 3, p. 701, doi. 10.1002/1521-4141(200203)32:3<701::AID-IMMU701>3.0.CO;2-T
By:
- Verkaik, Nicole S.;
- Esveldt-van Lange, Rebecca E. E.;
- Heemst, Diana van;
- Brüggenwirth, Hennie T.;
- Hoeijmakers, Jan H. J.;
- Zdzienicka, Malgorzata Z.;
- Gent, Dik C. van
Publication type:
Article

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