Found: 29
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DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.
- Published in:
- Diabetologia, 2019, v. 62, n. 5, p. 845, doi. 10.1007/s00125-019-4824-2
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- Article
Novel approaches to restore beta cell function in prediabetes and type 2 diabetes.
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- Diabetologia, 2018, v. 61, n. 9, p. 1895, doi. 10.1007/s00125-018-4658-3
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- Article
Emerging Roles of Small GTPases in Islet β-Cell Function.
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- Cells (2073-4409), 2021, v. 10, n. 6, p. 1503, doi. 10.3390/cells10061503
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- Article
Syntaxin 4 Mediates NF-κB Signaling and Chemokine Ligand Expression via Specific Interaction With IκBβ.
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- 2021
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- Publication type:
- journal article
Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets.
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- 2018
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- Publication type:
- journal article
Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function.
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- 2018
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- Publication type:
- journal article
Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
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- 2010
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- journal article
Protein Farnesylation--Dependent Raf/Extracellular Signal--Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic β-Cells.
- Published in:
- Diabetes, 2010, v. 59, n. 4, p. 967, doi. 10.2337/db09-1334
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- Publication type:
- Article
Tiam1-Mediated Activation of Rac1 Is Necessary, but Not Sufficient for Glucose-Stimulated Insulin Secretion in INS 832/13 Cells.
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- Diabetes, 2007, v. 56, p. A437
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- Publication type:
- Article
Hepatic Growth Factor Exerts Cytoprotective Effects Against IL-1β-Induced Metabolic Dysfunction in the Islet Beta Cells: Potential Role for STAT3.
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- Diabetes, 2007, v. 56, p. A414
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- Publication type:
- Article
Dominant-Negative α-Subunit of Farnesyl- and Geranyltransferase Inhibits Glucose-Stimulated, but Not KCl-Stimulated, Insulin Secretion in INS 832/13 Cells.
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- Diabetes, 2007, v. 56, n. 1, p. 204, doi. 10.2337/db06-0668
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- Article
Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.
- Published in:
- 2005
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- Publication type:
- journal article
Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+.
- Published in:
- 2005
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- Publication type:
- journal article
Mitochondrial Dysfunction, Oxidative Stress, and Inter-Organ Miscommunications in T2D Progression.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1504, doi. 10.3390/ijms25031504
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- Publication type:
- Article
A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 137, doi. 10.3390/ijms25010137
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- Article
Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1833, doi. 10.3390/ijms22041833
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- Article
Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis.
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- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.821849
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- Article
Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic β-cells.
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- Endocrine (1355008X), 2007, v. 31, n. 3, p. 248, doi. 10.1007/s12020-007-0046-3
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- Publication type:
- Article
Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells: potential regulation by IL-1β.
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- Apoptosis, 2006, v. 11, n. 8, p. 1401, doi. 10.1007/s10495-006-8371-1
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- Article
Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28061-w
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- Publication type:
- Article
VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.
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- Diabetologia, 2015, v. 58, n. 11, p. 2573, doi. 10.1007/s00125-015-3707-4
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- Publication type:
- Article
TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
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- Diabetologia, 2014, v. 57, n. 5, p. 1047, doi. 10.1007/s00125-014-3194-z
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- Publication type:
- Article
Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic β-Cells.
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- Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 6, p. 2110, doi. 10.1159/000447907
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- Article
NSC23766, a Known Inhibitor of Tiam1- Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model.
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- Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 2, p. 760, doi. 10.1159/000445666
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- Article
Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation.
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- Cellular Physiology & Biochemistry (Karger AG), 2015, v. 36, n. 1, p. 208, doi. 10.1159/000374065
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- Publication type:
- Article
Nm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis.
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- Cellular Physiology & Biochemistry (Karger AG), 2013, v. 32, n. 3, p. 533, doi. 10.1159/000354457
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- Article
A novel histone deacetylase inhibitor prevents IL-1β induced metabolic dysfunction in pancreatic β-cells.
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- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 1877, doi. 10.1111/j.1582-4934.2008.00672.x
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- Article
Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cells.
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- Apoptosis, 2014, v. 19, n. 12, p. 1691, doi. 10.1007/s10495-014-1038-4
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- Publication type:
- Article
Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function.
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- Antioxidants, 2023, v. 12, n. 9, p. 1658, doi. 10.3390/antiox12091658
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- Article