Works by Vaughan, Tristan J.

Results: 16

Antibody-Induced Lysis of Isolated Rat Epididymal Adipocytes and Complement Activation In Vivo.

Published in:

Obesity (19307381), 2002, v. 10, n. 2, p. 122, doi. 10.1038/oby.2002.19

By:

Dickinson, Keith;
North, Tracey J.;
Telford, Gary;
Smith, Susan E.;
Edwards, Bryan M.;
Main, Sarah H.;
Field, Ray;
Hatton, Diane;
Vaughan, Tristan J.;
Flint, David J.;
Jones, Robert B.

Publication type:

Article

Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155340

By:

Güler-Gane, Gülin;
Kidd, Sara;
Sridharan, Sudharsan;
Vaughan, Tristan J.;
Wilkinson, Trevor C. I.;
Tigue, Natalie J.

Publication type:

Article

Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0214545

By:

Schindler, Christina;
Collinson, Andie;
Matthews, Carl;
Pointon, Amy;
Jenkinson, Lesley;
Minter, Ralph R.;
Vaughan, Tristan J.;
Tigue, Natalie J.

Publication type:

Article

Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope “tags”.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 1, p. 129, doi. 10.4161/19420862.2014.985489

By:

Percival-Alwyn, Jennifer L;
England, Elizabeth;
Kemp, Benjamin;
Rapley, Laura;
Davis, Nicola HE;
McCarthy, Grant R;
Majithiya, Jayesh B;
Corkill, Dominic J;
Welsted, Sarah;
Minton, Kevin;
Cohen, E Suzanne;
Robinson, Matthew J;
Dobson, Claire;
Wilkinson, Trevor CI;
Vaughan, Tristan J;
Groves, Maria AT;
Tigue, Natalie J

Publication type:

Article

Affinity maturation of a novel antagonistic human monoclonal antibody with a long V H CDR3 targeting the Class A GPCR formyl-peptide receptor 1.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 1, p. 152, doi. 10.4161/19420862.2014.985158

By:

Douthwaite, Julie A;
Sridharan, Sudharsan;
Huntington, Catherine;
Hammersley, Jayne;
Marwood, Rose;
Hakulinen, Jonna K;
Ek, Margareta;
Sjögren, Tove;
Rider, David;
Privezentzev, Cyril;
Seaman, Jonathan C;
Cariuk, Peter;
Knights, Vikki;
Young, Joyce;
Wilkinson, Trevor;
Sleeman, Matthew;
Finch, Donna K;
Lowe, David C;
Vaughan, Tristan J

Publication type:

Article

Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes.

Published in:

mAbs (1942-0862), 2014, v. 6, n. 6, p. 1425, doi. 10.4161/mabs.34376

By:

Rossant, Christine J;
Carroll, Danielle;
Huang, Ling;
Elvin, John;
Neal, Frances;
Walker, Edward;
Benschop, Joris J;
Kim, Eldar E;
Barry, Simon T;
Vaughan, Tristan J

Publication type:

Article

Antibody VH and VL recombination using phage and ribosome display technologies reveals distinct structural routes to affinity improvements with VH-VL interface residues providing important structural diversity.

Published in:

mAbs (1942-0862), 2014, v. 6, n. 1, p. 1, doi. 10.4161/mabs.27261

By:

Groves, Maria A. T.;
Amanuel, Lily;
Campbell, Jamie I.;
Rees, D. Gareth;
Sridharan, Sudharsan;
Finch, Donna K.;
Lowe, David C.;
Vaughan, Tristan J.

Publication type:

Article

Experimentally guided computational antibody affinity maturation with de novo docking modelling and rational design.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.pcbi.1006980

By:

Cannon, Daniel A.;
Shan, Lu;
Du, Qun;
Shirinian, Lena;
Rickert, Keith W.;
Rosenthal, Kim L.;
IIIKorade, Martin;
van Vlerken-Ysla, Lilian E.;
Buchanan, Andrew;
Vaughan, Tristan J.;
Damschroder, Melissa M.;
Popovic, Bojana

Publication type:

Article

A direct role for SNX9 in the biogenesis of filopodia.

Published in:

Journal of Cell Biology, 2020, v. 219, n. 4, p. 1, doi. 10.1083/jcb.201909178

By:

Jarsch, Iris K.;
Gadsby, Jonathan R.;
Nuccitelli, Annalisa;
Mason, Julia;
Shimo, Hanae;
Pilloux, Ludovic;
Marzook, Bishara;
Mulvey, Claire M.;
Dobramysl, Ulrich;
Bradshaw, Charles R.;
Lilley, Kathryn S.;
Hayward, Richard D.;
Vaughan, Tristan J.;
Dobson, Claire L.;
Gallop, Jennifer L.

Publication type:

Article

Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38842-x

By:

Vousden, Katherine A.;
Lundqvist, Tomas;
Popovic, Bojana;
Naiman, Brian;
Carruthers, Alan M.;
Newton, Philip;
Johnson, Daniel J. D.;
Pomowski, Anja;
Wilkinson, Trevor;
Dufner, Patrick;
de Mendez, Isabelle;
Mallinder, Philip R.;
Murray, Clare;
Strain, Martin;
Connor, Jane;
Murray, Lynne A.;
Sleeman, Matthew A.;
Lowe, David C.;
Huntington, James A.;
Vaughan, Tristan J.

Publication type:

Article

Interactions Between the Gravitostat and the Fibroblast Growth Factor System for the Regulation of Body Weight.

Published in:

Endocrinology, 2019, v. 160, n. 5, p. 1057, doi. 10.1210/en.2018-01002

By:

Palsdottir, Vilborg;
Windahl, Sara H;
Hägg, Daniel A;
Keantar, Hanna;
Bellman, Jakob;
Buchanan, Andrew;
Vaughan, Tristan J;
Lindén, Daniel;
Jansson, John-Olov;
Ohlsson, Claes

Publication type:

Article

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15125-y

By:

Macleod, Olivia J. S.;
Bart, Jean-Mathieu;
MacGregor, Paula;
Peacock, Lori;
Savill, Nicholas J.;
Hester, Svenja;
Ravel, Sophie;
Sunter, Jack D.;
Trevor, Camilla;
Rust, Steven;
Vaughan, Tristan J.;
Minter, Ralph;
Mohammed, Shabaz;
Gibson, Wendy;
Taylor, Martin C.;
Higgins, Matthew K.;
Carrington, Mark

Publication type:

Article

Evolution of Biologics Screening Technologies.

Published in:

Pharmaceuticals (14248247), 2013, v. 6, n. 6, p. 681, doi. 10.3390/ph6050681

By:

Cariuk, Peter;
Gardener, Matthew J.;
Vaughan, Tristan J.

Publication type:

Article

Evolution of Biologics Screening Technologies.

Published in:

Pharmaceuticals (14248247), 2013, v. 6, n. 5, p. 681, doi. 10.3390/ph6050681

By:

Cariuk, Peter;
Gardenr, Matthew J.;
Vaughan, Tristan J.

Publication type:

Article

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non‐clinical species and Alzheimer's disease patients.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 11, p. 7762, doi. 10.1002/alz.14238

By:

Lloyd, Christopher;
Freskgård, Per‐Ola;
Newton, Philip;
Lowne, David;
Nickson, Adrian;
Bogstedt, Anna;
Eketjäll, Susanna;
Höglund, Kina;
Gustavsson, Susanne;
Welsh, Fraser;
Chessell, Tharani;
McFarlane, Mary;
Bhat, Ratan V.;
Turner, Richard;
Perkinton, Michael S.;
Santisteban Valencia, Zulma;
Lindqvist, Eva;
Pomfret, Michael;
Dudley, Amanda D.;
Vaughan, Tristan J.

Publication type:

Article

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 5, p. 1, doi. 10.1371/journal.pntd.0007373

By:

MacGregor, Paula;
Gonzalez-Munoz, Andrea L.;
Jobe, Fatoumatta;
Taylor, Martin C.;
Rust, Steven;
Sandercock, Alan M.;
Macleod, Olivia J. S.;
Van Bocxlaer, Katrien;
Francisco, Amanda F.;
D’Hooge, Francois;
Tiberghien, Arnaud;
Barry, Conor S.;
Howard, Philip;
Higgins, Matthew K.;
Vaughan, Tristan J.;
Minter, Ralph;
Carrington, Mark

Publication type:

Article