Works by Varani, Luca

Results: 23

Rationally Modified Estrogen Receptor Protein as a Bio-Recognition Element for the Detection of EDC Pollutants: Strategies and Opportunities.

Published in:

International Journal of Environmental Research & Public Health, 2015, v. 12, n. 3, p. 2612, doi. 10.3390/ijerph120302612

By:

Pedotti, Mattia;
Viviana Ferrero, Valentina Elisabetta;
Lettieri, Teresa;
Colpo, Pascal;
Follonier, Stephane;
Calzolai, Luigi;
Varani, Luca

Publication type:

Article

Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23880-9

By:

Garofalo, Maura;
Piccoli, Luca;
Romeo, Margherita;
Barzago, Maria Monica;
Ravasio, Sara;
Foglierini, Mathilde;
Matkovic, Milos;
Sgrignani, Jacopo;
De Gasparo, Raoul;
Prunotto, Marco;
Varani, Luca;
Diomede, Luisa;
Michielin, Olivier;
Lanzavecchia, Antonio;
Cavalli, Andrea

Publication type:

Article

Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology.

Published in:

Global Challenges, 2023, v. 7, n. 10, p. 1, doi. 10.1002/gch2.202300088

By:

Peissert, Frederik;
Pedotti, Mattia;
Corbellari, Riccardo;
Simonelli, Luca;
De Gasparo, Raoul;
Tamagnini, Elia;
Plüss, Louis;
Elsayed, Abdullah;
Matasci, Mattia;
De Luca, Roberto;
Cassaniti, Irene;
Sammartino, Jose' Camilla;
Piralla, Antonio;
Baldanti, Fausto;
Neri, Dario;
Varani, Luca

Publication type:

Article

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14875, doi. 10.3390/ijms241914875

By:

Guerrini, Giuditta;
Mehn, Dora;
Fumagalli, Francesco;
Gioria, Sabrina;
Pedotti, Mattia;
Simonelli, Luca;
Bianchini, Filippo;
Robbiani, Davide F.;
Varani, Luca;
Calzolai, Luigi

Publication type:

Article

Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin.

Published in:

International Journal of Molecular Sciences, 2011, v. 12, n. 1, p. 226, doi. 10.3390/ijms12010226

By:

Pedotti, Mattia;
Simonelli, Luca;
Livoti, Elsa;
Varani, Luca

Publication type:

Article

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity.

Published in:

PLoS Pathogens, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.ppat.1007335

By:

Bardelli, Marco;
Frontzek, Karl;
Simonelli, Luca;
Hornemann, Simone;
Pedotti, Mattia;
Mazzola, Federica;
Carta, Manfredi;
Eckhardt, Valeria;
D’Antuono, Rocco;
Virgilio, Tommaso;
González, Santiago F.;
Aguzzi, Adriano;
Varani, Luca

Publication type:

Article

Comparative Assessment of the Binding and Neutralisation Activity of Bispecific Antibodies Against SARS-CoV-2 Variants.

Published in:

Antibody Therapeutics, 2023, v. 6, n. 1, p. 49, doi. 10.1093/abt/tbac032

By:

Dean, Alexis Q;
Stauft, Charles B;
Twomey, Julianne D;
Tan, Joshua;
Varani, Luca;
Wang, Tony T;
Zhang, Baolin

Publication type:

Article

High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression.

Published in:

OncoImmunology, 2018, v. 7, n. 6, p. 1, doi. 10.1080/2162402X.2018.1438109

By:

Yasinska, Inna M.;
Gonçalves Silva, Isabel;
Sakhnevych, Svetlana S.;
Ruegg, Laura;
Hussain, Rohanah;
Siligardi, Giuliano;
Fiedler, Walter;
Wellbrock, Jasmin;
Bardelli, Marco;
Varani, Luca;
Raap, Ulrike;
Berger, Steffen;
Gibbs, Bernhard F.;
Fasler-Kan, Elizaveta;
Sumbayev, Vadim V.

Publication type:

Article

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells.

Published in:

OncoImmunology, 2016, v. 5, n. 7, p. 1, doi. 10.1080/2162402X.2016.1195535

By:

Gonçalves Silva, Isabel;
Rüegg, Laura;
Gibbs, Bernhard F.;
Bardelli, Marco;
Fruehwirth, Alexander;
Varani, Luca;
Berger, Steffen M.;
Fasler-Kan, Elizaveta;
Sumbayev, Vadim V.

Publication type:

Article

A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto)

Published in:

2000

By:

Yasuda, Minoru;
Takamatsu, Junichi;
D'Souza, Ian;
Crowther, R. Anthony;
Kawamata, Toshio;
Hasegawa, Masato;
Hasegawa, Hiroshi;
Grazia Spillantini, Maria;
Tanimukai, Satoshi;
Poorkaj, Parvoneh;
Varani, Luca;
Varani, Gabriele;
Iwatsubo, Takeshi;
Goedert, Michel;
Schellenberg, Gerard D.;
Tanaka, Chikako;
Yasuda, M;
Takamatsu, J;
D'Souza, I;
Crowther, R A

Publication type:

journal article

Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.

Published in:

Nucleic Acids Research, 2000, v. 28, n. 3, p. 710, doi. 10.1093/nar/28.3.710

By:

Varani, Luca;
Spillantini, Maria Grazia;
Goedert, Michel;
Varani, Gabriele

Publication type:

Article

Gold Nanoparticles Downregulate Interleukin-1β-Induced Pro-Inflammatory Responses.

Published in:

Small, 2013, v. 9, n. 3, p. 472, doi. 10.1002/smll.201201528

By:

Sumbayev, Vadim V.;
Yasinska, Inna M.;
Garcia, Cesar Pascual;
Gilliland, Douglas;
Lall, Gurprit S.;
Gibbs, Bernhard F.;
Bonsall, David R.;
Varani, Luca;
Rossi, François;
Calzolai, Luigi

Publication type:

Article

The NMR structure of the 38 kDa U1A protein ? PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein.

Published in:

Nature Structural Biology, 2000, v. 7, n. 4, p. 329

By:

Varani, Luca;
Gunderson, Samuel I.;
Mattaj, Iain W.;
Kay, Lewis E.;
Neuhaus, David;
Varani, Gabriele

Publication type:

Article

Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.580557

By:

Yasinska, Inna M.;
Meyer, N. Helge;
Schlichtner, Stephanie;
Hussain, Rohanah;
Siligardi, Giuliano;
Casely-Hayford, Maxwell;
Fiedler, Walter;
Wellbrock, Jasmin;
Desmet, Cloe;
Calzolai, Luigi;
Varani, Luca;
Berger, Steffen M.;
Raap, Ulrike;
Gibbs, Bernhard F.;
Fasler-Kan, Elizaveta;
Sumbayev, Vadim V.

Publication type:

Article

Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors.

Published in:

Biosensors (2079-6374), 2018, v. 8, n. 1, p. 1, doi. 10.3390/bios8010001

By:

La Spina, Rita;
Ferrero, Valentina E. V.;
Aiello, Venera;
Pedotti, Mattia;
Varani, Luca;
Lettieri, Teresa;
Calzolai, Luigi;
Haasnoot, Willem;
Colpo, Pascal

Publication type:

Article

Opening Study on the Development of a New Biosensor for Metal Toxicity Based on Pseudomonas fluorescens Pyoverdine.

Published in:

Biosensors (2079-6374), 2013, v. 3, n. 4, p. 385, doi. 10.3390/bios3040385

By:

Chiadò, Alessandro;
Varani, Luca;
Bosco, Francesca;
Marmo, Luca

Publication type:

Article

Rational Modification of Estrogen Receptor by Combination of Computational and Experimental Analysis.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102658

By:

Ferrero, Valentina Elisabetta Viviana;
Pedotti, Mattia;
Chiadò, Alessandro;
Simonelli, Luca;
Calzolai, Luigi;
Varani, Luca;
Lettieri, Teresa

Publication type:

Article

Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055561

By:

Simonelli, Luca;
Pedotti, Mattia;
Beltramello, Martina;
Livoti, Elsa;
Calzolai, Luigi;
Sallusto, Federica;
Lanzavecchia, Antonio;
Varani, Luca

Publication type:

Article

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01594

By:

Yasinska, Inna M.;
Sakhnevych, Svetlana S.;
Pavlova, Ludmila;
Teo Hansen Selnø, Anette;
Teuscher Abeleira, Ana Maria;
Benlaouer, Ouafa;
Gonçalves Silva, Isabel;
Mosimann, Marianne;
Varani, Luca;
Bardelli, Marco;
Hussain, Rohanah;
Siligardi, Giuliano;
Cholewa, Dietmar;
Berger, Steffen M.;
Gibbs, Bernhard F.;
Ushkaryov, Yuri A.;
Fasler-Kan, Elizaveta;
Klenova, Elena;
Sumbayev, Vadim V.

Publication type:

Article

Receptor-based high-throughput screening and identification of estrogens in dietary supplements using bioaffinity liquid-chromatography ion mobility mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 27, p. 9427, doi. 10.1007/s00216-013-7384-1

By:

Aqai, Payam;
Blesa, Natalia Gómez;
Major, Hilary;
Pedotti, Mattia;
Varani, Luca;
Ferrero, Valentina E. V.;
Haasnoot, Willem;
Nielen, Michel W. F.

Publication type:

Article

Upconversion of Intergroup Hot-Carrier Noise in Semiconductors Operating Under Periodic Large-Signal Conditions.

Published in:

Fluctuation & Noise Letters, 2003, v. 3, n. 1, p. L51, doi. 10.1142/S0219477503001087

By:

Shiktorov, Pavel;
Starikov, Evgenij;
Gruǽinskis, Viktoras;
Perez, Susana;
Gonzalez, Tomas;
Reggiani, Lino;
Varani, Luca;
Vaissiere, Jean-Claude

Publication type:

Article

Admittance Field Method for the Calculation of the Spectral Density of Current Fluctuations.

Published in:

Fluctuation & Noise Letters, 2001, v. 1, n. 1, p. R1, doi. 10.1142/S0219477501000020

By:

Shiktorov, Pavel;
Starikov, Evgenij;
Gruǽinskis, Viktoras;
Varani, Luca;
Vaissiere, Jean-Claude;
Nougier, Jean-Pierre;
Reggiani, Lino

Publication type:

Article

Effects of Antibody Responses to Pre-Existing Coronaviruses on Disease Severity and Complement Activation in COVID-19 Patients.

Published in:

Microorganisms, 2022, v. 10, n. 6, p. 1191, doi. 10.3390/microorganisms10061191

By:

Cugno, Massimo;
Meroni, Pier Luigi;
Consonni, Dario;
Griffini, Samantha;
Grovetti, Elena;
Novembrino, Cristina;
Torri, Adriana;
Griffante, Gloria;
Gariglio, Marisa;
Varani, Luca;
Peyvandi, Flora

Publication type:

Article