Works matching AU Vanmechelen, Eugeen


Results: 136
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    Plasma biomarkers combinations for prescreening rapid amyloid accumulation in cognitively unimpaired individuals at‐risk of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.091423
    By:
    • Contador, José;
    • Milà‐Alomà, Marta;
    • Escalante, Armand González;
    • Ashton, Nicholas J.;
    • Shekari, Mahnaz;
    • Ortiz‐Romero, Paula;
    • Karikari, Thomas K;
    • Vanmechelen, Eugeen;
    • Day, Theresa A.;
    • Dage, Jeffrey L.;
    • Zetterberg, Henrik;
    • Gispert, Juan Domingo;
    • Blennow, Kaj;
    • Suarez‐Calvet, Marc
    Publication type:
    Article
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    Associations between blood‐based biomarkers, synaptic density and Alzheimer's disease hallmarks in the brains of nondemented elderly.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.090738
    By:
    • Meyer, Steffi De;
    • Alali, Soha;
    • Laroy, Maarten;
    • Casteele, Thomas Vande;
    • Cauwenberge, Margot Van;
    • Goossens, Julie;
    • Rocker, Charlotte De;
    • Vanbrabant, Jeroen;
    • Vanmechelen, Eugeen;
    • Dupont, Patrick;
    • Laere, Koen Van;
    • Vandenbulcke, Mathieu;
    • Emsell, Louise;
    • Poesen, Koen
    Publication type:
    Article
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    Prognostic value of a novel plasma pTau217 assay for amyloid accumulation in healthy elderly.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.088710
    By:
    • Meyer, Steffi De;
    • Luckett, Emma S.;
    • Schaeverbeke, Jolien;
    • Laere, Koen Van;
    • Vanbrabant, Jeroen;
    • Vanmechelen, Eugeen;
    • Dupont, Patrick;
    • Molfetta, Guglielmo Di;
    • Zetterberg, Henrik;
    • Ashton, Nicholas J.;
    • Poesen, Koen;
    • Vandenberghe, Rik
    Publication type:
    Article
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    Cerebrospinal fluid p‐tau181, 217, and 231 in definite Creutzfeldt–Jakob disease with and without concomitant pathologies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5324, doi. 10.1002/alz.13907
    By:
    • Emeršič, Andreja;
    • Ashton, Nicholas J.;
    • Vrillon, Agathe;
    • Lantero‐Rodriguez, Juan;
    • Mlakar, Jernej;
    • Gregorič Kramberger, Milica;
    • Gonzalez‐Ortiz, Fernando;
    • Kac, Przemysław R.;
    • Dulewicz, Maciej;
    • Hanrieder, Jörg;
    • Vanmechelen, Eugeen;
    • Rot, Uroš;
    • Zetterberg, Henrik;
    • Karikari, Thomas K.;
    • Čučnik, Saša;
    • Blennow, Kaj
    Publication type:
    Article
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    Blood‐based SNAP‐25 and VAMP‐2 in Alzheimer's disease; relation to cognition, atrophy and synaptic density.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083128
    By:
    • Sauer, Mathias;
    • De Rocker, Charlotte;
    • Grötschel, Lana;
    • Goossens, Julie;
    • Benedet, Andrea L.;
    • Schöll, Michael;
    • Nilsson, Johanna;
    • Brinkmalm, Ann;
    • Janelidze, Shorena;
    • Stomrud, Erik;
    • O'Brien, John T;
    • Chouliaras, Leonidas;
    • Malpetti, Maura;
    • Rosa‐Neto, Pedro;
    • Rowe, James B.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Hansson, Oskar;
    • Vanmechelen, Eugeen;
    • Ashton, Nicholas J.
    Publication type:
    Article
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    The detection of phosphorylated tau in tear fluid.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083029
    By:
    • Molfetta, Guglielmo Di;
    • Demleitner, Antonia Franziska;
    • Gomes, Lucas Arujo Caldi;
    • Jeromin, Andreas;
    • Vanmechelen, Eugeen;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Lingor, Paul;
    • Ashton, Nicholas J.
    Publication type:
    Article
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    Optimizing plasma biomarkers combinations for the detection of amyloid pathology in cognitively unimpaired individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082742
    By:
    • Contador, José;
    • Milà‐Alomà, Marta;
    • Escalante, Armand González;
    • Ashton, Nicholas J.;
    • Shekari, Mahnaz;
    • Ortiz‐Romero, Paula;
    • Karikari, Thomas K;
    • Vanmechelen, Eugeen;
    • Day, Theresa A.;
    • Dage, Jeff L.;
    • Zetterberg, Henrik;
    • Gispert, Juan Domingo;
    • Blennow, Kaj;
    • Suárez‐Calvet, Marc
    Publication type:
    Article
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    Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology.

    Published in:
    JAMA Neurology, 2024, v. 81, n. 3, p. 255, doi. 10.1001/jamaneurol.2023.5319
    By:
    • Ashton, Nicholas J.;
    • Brum, Wagner S.;
    • Di Molfetta, Guglielmo;
    • Benedet, Andrea L.;
    • Arslan, Burak;
    • Jonaitis, Erin;
    • Langhough, Rebecca E.;
    • Cody, Karly;
    • Wilson, Rachael;
    • Carlsson, Cynthia M.;
    • Vanmechelen, Eugeen;
    • Montoliu-Gaya, Laia;
    • Lantero-Rodriguez, Juan;
    • Rahmouni, Nesrine;
    • Tissot, Cecile;
    • Stevenson, Jenna;
    • Servaes, Stijn;
    • Therriault, Joseph;
    • Pascoal, Tharick;
    • Lleó, Alberto
    Publication type:
    Article
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    Assessing the commutability of reference material formats for the harmonization of amyloid-β measurements.

    Published in:
    Clinical Chemistry & Laboratory Medicine, 2016, v. 54, n. 7, p. 1177, doi. 10.1515/cclm-2015-0733
    By:
    • Bjerke, Maria;
    • Andreasson, Ulf;
    • Kuhlmann, Julia;
    • Portelius, Erik;
    • Pannee, Josef;
    • Lewczuk, Piotr;
    • Umek, Robert M.;
    • Vanmechelen, Eugeen;
    • Vanderstichele, Hugo;
    • Stoops, Erik;
    • Lewis, Jennifer;
    • Vandijck, Manu;
    • Kostanjevecki, Vesna;
    • Jeromin, Andreas;
    • Salamone, Salvatore J.;
    • Schmidt, Oliver;
    • Matzen, Anja;
    • Madin, Kairat;
    • Eichenlaub, Udo;
    • Bittner, Tobias
    Publication type:
    Article
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    Analytical performance and clinical utility of the INNOTEST<sup>®</sup> PHOSPHO-TAU<sub>(181P)</sub> assay for discrimination between Alzheimer's disease and dementia with Lewy bodies.

    Published in:
    Clinical Chemistry & Laboratory Medicine, 2006, v. 44, n. 12, p. 1472, doi. 10.1515/CCLM.2006.258
    By:
    • Vanderstichele, Hugo;
    • De Vreese, Karen;
    • Blennow, Kaj;
    • Andreasen, Niels;
    • Sindic, Christian;
    • Ivanoiu, Adrian;
    • Hampel, Harald;
    • Bürger, Katharina;
    • Parnetti, Lucilla;
    • Lanari, Alessia;
    • Padovani, Allesandro;
    • DiLuca, Monica;
    • Bläser, Miriam;
    • Ohrfelt Olsson, Annika;
    • Pottel, Hans;
    • Hulstaert, Frank;
    • Vanmechelen, Eugeen
    Publication type:
    Article
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    Multicenter Analytical Validation of Aβ40 Immunoassays.

    Published in:
    Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00310
    By:
    • van Waalwijk van Doorn, Linda J. C.;
    • Kulic, Luka;
    • Koel-Simmelink, Marleen J. A.;
    • Kuiperij, H. Bea;
    • Versleijen, Alexandra A. M.;
    • Struyfs, Hanne;
    • Twaalfhoven, Harry A. M.;
    • Fourier, Anthony;
    • Engelborghs, Sebastiaan;
    • Perret-Liaudet, Armand;
    • Lehmann, Sylvain;
    • Verbeek, Marcel M.;
    • Vanmechelen, Eugeen J. M.;
    • Teunissen, Charlotte E.
    Publication type:
    Article
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    A Novel Neurofilament Light Chain ELISA Validated in Patients with Alzheimer's Disease, Frontotemporal Dementia, and Subjective Cognitive Decline, and the Evaluation of Candidate Proteins for Immunoassay Calibration.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7221, doi. 10.3390/ijms23137221
    By:
    • Das, Shreyasee;
    • Dewit, Nele;
    • Jacobs, Dirk;
    • Pijnenburg, Yolande A. L.;
    • In 't Veld, Sjors G. J. G.;
    • Coppens, Salomé;
    • Quaglia, Milena;
    • Hirtz, Christophe;
    • Teunissen, Charlotte E.;
    • Vanmechelen, Eugeen
    Publication type:
    Article
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    Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased ABeta42 secretion.

    Published in:
    Human Molecular Genetics, 1999, v. 8, n. 8, p. 1529, doi. 10.1093/hmg/8.8.1529
    By:
    • Jonghe, Chris De;
    • Cruts, Marc;
    • Rogaeva, Ekaterina A.;
    • Tysoe, Carolyn;
    • Singleton, Andrew;
    • Vanderstichele, Hugo;
    • Meschino, Wendy;
    • Dermaut, Bart;
    • Vanderhoeven, Inge;
    • Backhovens, Hubert;
    • Vanmechelen, Eugeen;
    • Morris, Christopher M.;
    • Hardy, John;
    • Rubinsztein, David C.;
    • St. George-Hyslop, Peter H.;
    • Van Broeckhoven, Christine
    Publication type:
    Article
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    The use of synaptic biomarkers in cerebrospinal fluid to differentiate behavioral variant of frontotemporal dementia from primary psychiatric disorders and Alzheimer's disease.

    Published in:
    Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01409-8
    By:
    • Das, Shreyasee;
    • van Engelen, Marie-Paule E.;
    • Goossens, Julie;
    • Jacobs, Dirk;
    • Bongers, Bram;
    • Fieldhouse, Jay L. P.;
    • Pijnenburg, Yolande A. L.;
    • Teunissen, Charlotte E.;
    • Vanmechelen, Eugeen;
    • Verberk, Inge M. W.
    Publication type:
    Article
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    Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected.

    Published in:
    EMBO Molecular Medicine, 2020, v. 12, n. 12, p. 1, doi. 10.15252/emmm.202012921
    By:
    • Suárez‐Calvet, Marc;
    • Karikari, Thomas K;
    • Ashton, Nicholas J;
    • Lantero Rodríguez, Juan;
    • Milà‐Alomà, Marta;
    • Gispert, Juan Domingo;
    • Salvadó, Gemma;
    • Minguillon, Carolina;
    • Fauria, Karine;
    • Shekari, Mahnaz;
    • Grau‐Rivera, Oriol;
    • Arenaza‐Urquijo, Eider M;
    • Sala‐Vila, Aleix;
    • Sánchez‐Benavides, Gonzalo;
    • González‐de‐Echávarri, José Maria;
    • Kollmorgen, Gwendlyn;
    • Stoops, Erik;
    • Vanmechelen, Eugeen;
    • Zetterberg, Henrik;
    • Blennow, Kaj
    Publication type:
    Article
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    Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

    Published in:
    Expert Review of Proteomics, 2008, v. 5, n. 2, p. 207, doi. 10.1586/14789450.5.2.207
    By:
    • Sergeant, Nicolas;
    • Bretteville, Alexis;
    • Hamdane, Malika;
    • Caillet-Boudin, Marie-Laure;
    • Grognet, Pierre;
    • Bombois, Stephanie;
    • Blum, David;
    • Delacourte, André;
    • Pasquier, Florence;
    • Vanmechelen, Eugeen;
    • Schraen-Maschke, Susanna;
    • Buée, Luc
    Publication type:
    Article
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    Validation of soluble amyloid-β precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases.

    Published in:
    Journal of Neurochemistry, 2016, v. 137, n. 1, p. 112, doi. 10.1111/jnc.13527
    By:
    • Waalwijk van Doorn, Linda J.C.;
    • Koel‐Simmelink, Marleen J.;
    • Haußmann, Ute;
    • Klafki, Hans;
    • Struyfs, Hanne;
    • Linning, Philipp;
    • Knölker, Hans‐Joachim;
    • Twaalfhoven, Harry;
    • Kuiperij, H. Bea;
    • Engelborghs, Sebastiaan;
    • Scheltens, Philip;
    • Verbeek, Marcel M.;
    • Vanmechelen, Eugeen;
    • Wiltfang, Jens;
    • Teunissen, Charlotte E.
    Publication type:
    Article
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    Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study.

    Published in:
    Clinical Chemistry, 2018, v. 64, n. 6, p. 927, doi. 10.1373/clinchem.2017.283028
    By:
    • Willemse, Eline A. J.;
    • De Vos, Ann;
    • Herries, Elizabeth M.;
    • Andreasson, Ulf;
    • Engelborghs, Sebastiaan;
    • van der Flier, Wiesje M.;
    • Scheltens, Philip;
    • Crimmins, Dan;
    • Ladenson, Jack H.;
    • Vanmechelen, Eugeen;
    • Zetterberg, Henrik;
    • Fagan, Anne M.;
    • Blennow, Kaj;
    • Bjerke, Maria;
    • Teunissen, Charlotte E.
    Publication type:
    Article
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    Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology.

    Published in:
    Acta Neuropathologica, 2021, v. 141, n. 5, p. 709, doi. 10.1007/s00401-021-02275-6
    By:
    • Ashton, Nicholas J.;
    • Pascoal, Tharick A.;
    • Karikari, Thomas K.;
    • Benedet, Andréa L.;
    • Lantero-Rodriguez, Juan;
    • Brinkmalm, Gunnar;
    • Snellman, Anniina;
    • Schöll, Michael;
    • Troakes, Claire;
    • Hye, Abdul;
    • Gauthier, Serge;
    • Vanmechelen, Eugeen;
    • Zetterberg, Henrik;
    • Rosa-Neto, Pedro;
    • Blennow, Kaj
    Publication type:
    Article
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    Intra-Individual Stability of CSF Biomarkers for Alzheimer's Disease over Two Years.

    Published in:
    Journal of Alzheimer's Disease, 2007, v. 12, n. 3, p. 255, doi. 10.3233/JAD-2007-12307
    By:
    • Zetterberg, Henrik;
    • Pedersen, Mona;
    • Lind, Karin;
    • Svensson, Maria;
    • Rolstad, Sindre;
    • Eckerström, Carl;
    • Syversen, Steinar;
    • Mattsson, Ulla-Britt;
    • Ysander, Christina;
    • Mattsson, Niklas;
    • Nordlund, Arto;
    • Vanderstichele, Hugo;
    • Vanmechelen, Eugeen;
    • Jonsson, Michael;
    • Edman, Åke;
    • Blennow, Kaj;
    • Wallin, Anders
    Publication type:
    Article
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    Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease.

    Published in:
    Brain: A Journal of Neurology, 2023, v. 146, n. 4, p. 1592, doi. 10.1093/brain/awac333
    By:
    • Janelidze, Shorena;
    • Bali, Divya;
    • Ashton, Nicholas J;
    • Barthélemy, Nicolas R;
    • Vanbrabant, Jeroen;
    • Stoops, Erik;
    • Vanmechelen, Eugeen;
    • He, Yingxin;
    • Dolado, Anna Orduña;
    • Triana-Baltzer, Gallen;
    • Pontecorvo, Michael J;
    • Zetterberg, Henrik;
    • Kolb, Hartmuth;
    • Vandijck, Manu;
    • Blennow, Kaj;
    • Bateman, Randall J;
    • Hansson, Oskar
    Publication type:
    Article
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    Plasma p‐tau231, p‐tau181, PET Biomarkers, and Cognitive Change in Older Adults.

    Published in:
    Annals of Neurology, 2022, v. 91, n. 4, p. 548, doi. 10.1002/ana.26308
    By:
    • Meyer, Pierre‐François;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K.;
    • Strikwerda‐Brown, Cherie;
    • Köbe, Theresa;
    • Gonneaud, Julie;
    • Pichet Binette, Alexa;
    • Ozlen, Hazal;
    • Yakoub, Yara;
    • Simrén, Joel;
    • Pannee, Josef;
    • Lantero‐Rodriguez, Juan;
    • Labonté, Anne;
    • Baker, Suzanne L.;
    • Schöll, Michael;
    • Vanmechelen, Eugeen;
    • Breitner, John C. S.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Poirier, Judes
    Publication type:
    Article
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    Evaluation of cerebrospinal fluid levels of VAMP-2 and SNAP-25 in a dementia with Lewy bodies clinical cohort stratified by Alzheimer's pathophysiological biomarkers.

    Published in:
    Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01685-y
    By:
    • González, Alba Cervantes;
    • Goossens, Julie;
    • Campuzano, Elena Vera;
    • Sala, Isabel;
    • Sánchez-Saudinós, M. Belén;
    • Rodríguez-Baz, Íñigo;
    • Lidón, Laia;
    • Perlaza, Danna;
    • Bejanin, Alexandre;
    • Haapasalo, Annakaisa;
    • Fortea, Juan;
    • Alcolea, Daniel;
    • Lleó, Alberto;
    • Vanmechelen, Eugeen;
    • Belbin, Olivia
    Publication type:
    Article
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    Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217.

    Published in:
    Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01620-7
    By:
    • Kovacech, Branislav;
    • Cullen, Nicholas C.;
    • Novak, Petr;
    • Hanes, Jozef;
    • Kontsekova, Eva;
    • Katina, Stanislav;
    • Parrak, Vojtech;
    • Fresser, Michal;
    • Vanbrabant, Jeroen;
    • Feldman, Howard H.;
    • Winblad, Bengt;
    • Stoops, Erik;
    • Vanmechelen, Eugeen;
    • Zilka, Norbert
    Publication type:
    Article