Works by Vangipurapu, Jagadish

Results: 28

Metabolomics, Genetics, and Environmental Factors: Intersecting Paths in Abdominal Aortic Aneurysm.
Published in:
International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1498, doi. 10.3390/ijms26041498
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Oravilahti, Anniina;
- Lusis, Aldons Jake;
- Laakso, Markku
Publication type:
Article
Microbiota-Related Metabolites and the Risk of Type 2 Diabetes.
Published in:
2020
By:
- Vangipurapu, Jagadish;
- Silva, Lilian Fernandes;
- Kuulasmaa, Teemu;
- Smith, Ulf;
- Markku Laakso;
- Fernandes Silva, Lilian;
- Laakso, Markku
Publication type:
journal article
Glycerol and Fatty Acids in Serum Predict the Development of Hyperglycemia and Type 2 Diabetes in Finnish Men.
Published in:
Diabetes Care, 2013, v. 36, n. 11, p. 3732, doi. 10.2337/dc13-0800
By:
- MAHENDRAN, YUVARAJ;
- CEDERBERG, HENNA;
- VANGIPURAPU, JAGADISH;
- KANGAS, ANTTI J.;
- SOININEN, PASI;
- KUUSISTO, JOHANNA;
- UUSITUPA, MATTI;
- ALA-KORPELA, MIKA;
- LAAKSO, MARKKU
Publication type:
Article
Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences.
Published in:
Human Genomics, 2021, v. 15, n. 1, p. 1, doi. 10.1186/s40246-021-00335-2
By:
- Ganel, Liron;
- Chen, Lei;
- Christ, Ryan;
- Vangipurapu, Jagadish;
- Young, Erica;
- Das, Indraniel;
- Kanchi, Krishna;
- Larson, David;
- Regier, Allison;
- Abel, Haley;
- Kang, Chul Joo;
- Scott, Alexandra;
- Havulinna, Aki;
- Chiang, Charleston W. K.;
- Service, Susan;
- Freimer, Nelson;
- Palotie, Aarno;
- Ripatti, Samuli;
- Kuusisto, Johanna;
- Boehnke, Michael
Publication type:
Article
An intronic variant in the GCKR gene is associated with multiple lipids.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46750-3
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Kuulasmaa, Teemu;
- Laakso, Markku
Publication type:
Article
Short Adult Stature Predicts Impaired β-Cell Function, Insulin Resistance, Glycemia, and Type 2 Diabetes in Finnish Men.
Published in:
2016
By:
- Vangipurapu, Jagadish;
- Stančáková, Alena;
- Jauhiainen, Raimo;
- Kuusisto, Johanna;
- Laakso, Markku;
- Stancáková, Alena
Publication type:
journal article
Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population.
Published in:
2016
By:
- Huopio, Hanna;
- Miettinen, Päivi J;
- Ilonen, Jorma;
- Nykänen, Päivi;
- Veijola, Riitta;
- Keskinen, Päivi;
- Näntö-Salonen, Kirsti;
- Vangipurapu, Jagadish;
- Raivo, Joose;
- Stančáková, Alena;
- Männistö, Jonna;
- Kuulasmaa, Teemu;
- Knip, Mikael;
- Otonkoski, Timo;
- Laakso, Markku
Publication type:
journal article
Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort.
Published in:
Thyroid, 2016, v. 26, n. 9, p. 1215, doi. 10.1089/thy.2016.0016
By:
- Löf, Christoffer;
- Patyra, Konrad;
- Kuulasmaa, Teemu;
- Vangipurapu, Jagadish;
- Undeutsch, Henriette;
- Jaeschke, Holger;
- Pajunen, Tuulia;
- Kero, Andreina;
- Krude, Heiko;
- Biebermann, Heike;
- Kleinau, Gunnar;
- Kühnen, Peter;
- Rantakari, Krista;
- Miettinen, Päivi;
- Kirjavainen, Turkka;
- Pursiheimo, Juha-Pekka;
- Mustila, Taina;
- Jääskeläinen, Jarmo;
- Ojaniemi, Marja;
- Toppari, Jorma
Publication type:
Article
Novel biomarkers associated with incident heart failure in 10 106 Finnish men.
Published in:
ESC Heart Failure, 2021, v. 8, n. 1, p. 605, doi. 10.1002/ehf2.13132
By:
- Jauhiainen, Raimo;
- Jauhiainen, Matti;
- Vangipurapu, Jagadish;
- Kuulasmaa, Teemu;
- Ala‐Korpela, Mika;
- Laakso, Markku;
- Kuusisto, Johanna
Publication type:
Article
Genetic basis and outcome in a nationwide study of Finnish patients with hypertrophic cardiomyopathy.
Published in:
ESC Heart Failure, 2019, v. 6, n. 2, p. 436, doi. 10.1002/ehf2.12420
By:
- Jääskeläinen, Pertti;
- Vangipurapu, Jagadish;
- Raivo, Joose;
- Kuulasmaa, Teemu;
- Heliö, Tiina;
- Aalto‐Setälä, Katriina;
- Kaartinen, Maija;
- Ilveskoski, Erkki;
- Vanninen, Sari;
- Hämäläinen, Liisa;
- Melin, John;
- Kokkonen, Jorma;
- Nieminen, Markku S.;
- Laakso, Markku;
- Kuusisto, Johanna
Publication type:
Article
Both Fasting and Glucose-Stimulated Proinsulin Levels Predict Hyperglycemia and Incident Type 2 Diabetes: A Population-Based Study of 9,396 Finnish Men.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124028
By:
- Vangipurapu, Jagadish;
- Stančáková, Alena;
- Kuulasmaa, Teemu;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
Article
Functional Variant in the GCKR Gene Affects Lactate Levels Differentially in the Fasting State and During Hyperglycemia.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34501-9
By:
- López Rodríguez, Maykel;
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Modi, Shalem;
- Kuusisto, Johanna;
- Kaikkonen, Minna U.;
- Laakso, Markku
Publication type:
Article
Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes.
Published in:
European Journal of Endocrinology, 2013, v. 169, n. 3, p. 291, doi. 10.1530/EJE-13-0286
By:
- Huopio, Hanna;
- Cederberg, Henna;
- Vangipurapu, Jagadish;
- Hakkarainen, Heidi;
- Pääkkönen, Mirja;
- Kuulasmaa, Teemu;
- Heinonen, Seppo;
- Laakso, Markku
Publication type:
Article
Metabolites as Risk Factors for Diabetic Retinopathy in Patients With Type 2 Diabetes: A 12-Year Follow-up Study.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 1, p. 100, doi. 10.1210/clinem/dgad452
By:
- Silva, Lilian Fernandes;
- Hokkanen, Jenna;
- Vangipurapu, Jagadish;
- Oravilahti, Anniina;
- Laakso, Markku
Publication type:
Article
The Association of 9 Amino Acids With Cardiovascular Events in Finnish Men in a 12-Year Follow-up Study.
Published in:
2021
By:
- Jauhiainen, Raimo;
- Vangipurapu, Jagadish;
- Laakso, Annamaria;
- Kuulasmaa, Teemu;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
journal article
Metabolite Signature of Albuminuria Involves Amino Acid Pathways in 8661 Finnish Men Without Diabetes.
Published in:
2021
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Smith, Ulf;
- Laakso, Markku
Publication type:
journal article
Metabolomics-Based Machine Learning for Predicting Mortality: Unveiling Multisystem Impacts on Health.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11636, doi. 10.3390/ijms252111636
By:
- Oravilahti, Anniina;
- Vangipurapu, Jagadish;
- Laakso, Markku;
- Fernandes Silva, Lilian
Publication type:
Article
Novel Metabolites Associated with Decreased GFR in Finnish Men: A 12-Year Follow-Up of the METSIM Cohort.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 10044, doi. 10.3390/ijms251810044
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Oravilahti, Anniina;
- Laakso, Markku
Publication type:
Article
Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease.
Published in:
Metabolites (2218-1989), 2023, v. 13, n. 2, p. 267, doi. 10.3390/metabo13020267
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Oravilahti, Anniina;
- Männistö, Ville;
- Laakso, Markku
Publication type:
Article
Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment.
Published in:
Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1159, doi. 10.3390/metabo12121159
By:
- Fernandes Silva, Lilian;
- Ravi, Rowmika;
- Vangipurapu, Jagadish;
- Oravilahti, Anniina;
- Laakso, Markku
Publication type:
Article
Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways.
Published in:
Metabolites (2218-1989), 2022, v. 12, n. 8, p. 753, doi. 10.3390/metabo12080753
By:
- Fernandes Silva, Lilian;
- Ravi, Rowmika;
- Vangipurapu, Jagadish;
- Laakso, Markku
Publication type:
Article
Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study.
Published in:
Metabolites (2218-1989), 2022, v. 12, n. 5, p. 437, doi. 10.3390/metabo12050437
By:
- Ravi, Rowmika;
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Maria, Maleeha;
- Raivo, Joose;
- Helisalmi, Seppo;
- Laakso, Markku
Publication type:
Article
The "Common Soil Hypothesis" Revisited—Risk Factors for Type 2 Diabetes and Cardiovascular Disease.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 10, p. 691, doi. 10.3390/metabo11100691
By:
- Fernandes Silva, Lilian;
- Vangipurapu, Jagadish;
- Laakso, Markku
Publication type:
Article
Markers of Tissue-Specific Insulin Resistance Predict the Worsening of Hyperglycemia, Incident Type 2 Diabetes and Cardiovascular Disease.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109772
By:
- FízeI'ová, Mária;
- Cederberg, Henna;
- Stančáková, Alena;
- Jauhiainen, Raimo;
- Vangipurapu, Jagadish;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
Article
Non-Cholesterol Sterol Levels Predict Hyperglycemia and Conversion to Type 2 Diabetes in Finnish Men.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067406
By:
- Cederberg, Henna;
- Gylling, Helena;
- Miettinen, Tatu A.;
- Paananen, Jussi;
- Vangipurapu, Jagadish;
- Pihlajamäki, Jussi;
- Kuulasmaa, Teemu;
- Stančáková, Alena;
- Smith, Ulf;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
Article
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Published in:
2019
By:
- Vangipurapu, Jagadish;
- Stancáková, Alena;
- Smith, Ulf;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
journal article
Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.
Published in:
Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456
By:
- Yaghootkar, Hanieh;
- Stancáková, Alena;
- Freathy, Rachel M.;
- Vangipurapu, Jagadish;
- Weedon, Michael N.;
- Weijia Xie;
- Wood, Andrew R.;
- Ferrannini, Ele;
- Mari, Andrea;
- Ring, Susan M.;
- Lawlor, Debbie A.;
- Smith, George Davey;
- Jørgensen, Torben;
- Hansen, Torben;
- Pedersen, Oluf;
- Steinthorsdottir, Valgerdur;
- Guðbjartsson, Daniel F.;
- Thorleifsson, Gudmar;
- Thorsteinsdottir, Unnur;
- Stefansson, Kari
Publication type:
Article
Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men.
Published in:
Diabetes, 2013, v. 62, n. 10, p. 3618, doi. 10.2337/db12-1363
By:
- Mahendran, Yuvaraj;
- Vangipurapu, Jagadish;
- Cederberg, Henna;
- Stancáková, Alena;
- Pihlajamäki, Jussi;
- Soininen, Pasi;
- Kangas, Antti J.;
- Paananen, Jussi;
- Civelek, Mete;
- Saleem, Niyas K.;
- Pajukanta, Päivi;
- Lusis, Aldons J.;
- Bonnycastle, Lori L.;
- Morken, Mario A.;
- Collins, Francis S.;
- Mohlke, Karen L.;
- Boehnke, Michael;
- Ala-Korpela, Mika;
- Kuusisto, Johanna;
- Laakso, Markku
Publication type:
Article