Works by Vandenbroucke, Roosmarijn

Results: 84

A Hidden Epithelial Barrier in the Brain with a Central Role in Regulating Brain Homeostasis. Implications for Aging.

Published in:

2016

By:

Vandenbroucke, Roosmarijn E.;
E Vandenbroucke, Roosmarijn

Publication type:

journal article

Modulation of Dendritic Cells by Lipid Grafted Polyelectrolyte Microcapsules.

Published in:

Advanced Functional Materials, 2012, v. 22, n. 20, p. 4236, doi. 10.1002/adfm.201103151

By:

De Temmerman, Marie-Luce;
Rejman, Joanna;
Lucas, Bart;
Vandenbroucke, Roosmarijn E.;
Libert, Claude;
Demeester, Jo;
De Smedt, Stefaan C.

Publication type:

Article

Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling.

Published in:

Journal of Extracellular Vesicles, 2023, v. 12, n. 2, p. 1, doi. 10.1002/jev2.12306

By:

Xie, Junhua;
Cools, Lien;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Pauwels, Marie J.;
Vlaeminck, Ine;
De Witte, Chloë;
EL Andaloussi, Samir;
Wierda, Keimpe;
De Groef, Lies;
Haesebrouck, Freddy;
Van Hoecke, Lien;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Microfluidic Interfaces for Chronic Bidirectional Access to the Brain.

Published in:

Advanced Healthcare Materials, 2024, v. 13, n. 22, p. 1, doi. 10.1002/adhm.202400438

By:

Marcigaglia, Simone;
De Plus, Robin;
Vandendriessche, Charysse;
Schiltz, Eleonore;
Cuypers, Marie‐Lynn;
Cools, Jordi;
Hoffman, Luis D.;
Vandenbroucke, Roosmarijn E.;
Dewilde, Maarten;
Haesler, Sebastian

Publication type:

Article

Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 12, p. e86, doi. 10.1093/nar/gkm440

By:

Vandenbroucke, Roosmarijn E.;
Lucas, Bart;
Demeester, Joseph;
De Smedt, Stefaan C.;
Sanders, Niek N.

Publication type:

Article

Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02814-w

By:

Claeys, Wouter;
Van Hoecke, Lien;
Lernout, Hannah;
De Nolf, Clint;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Verhaege, Daan;
Castelein, Jonas;
Geerts, Anja;
Van Steenkiste, Christophe;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.

Published in:

Glia (0894-1491), 2020, v. 68, n. 12, p. 2643, doi. 10.1002/glia.23875

By:

Lefevere, Evy;
Salinas‐Navarro, Manuel;
Andries, Lien;
Noterdaeme, Lut;
Etienne, Isabelle;
Van Wonterghem, Elien;
Vinckier, Stefan;
Davis, Benjamin M.;
Van Bergen, Tine;
Van Hove, Inge;
Movahedi, Kiavash;
Vandenbroucke, Roosmarijn E.;
Moons, Lieve;
De Groef, Lies

Publication type:

Article

Into rather unexplored terrain-transcellular transport across the blood-brain barrier.

Published in:

Glia (0894-1491), 2016, v. 64, n. 7, p. 1097, doi. 10.1002/glia.22960

By:

De Bock, Marijke;
Van Haver, Valérie;
Vandenbroucke, Roosmarijn E.;
Decrock, Elke;
Wang, Nan;
Leybaert, Luc

Publication type:

Article

Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β-amino esters).

Published in:

Journal of Gene Medicine, 2008, v. 10, n. 7, p. 783, doi. 10.1002/jgm.1202

By:

Vandenbroucke, Roosmarijn E.;
De Geest, Bruno G.;
Bonné, Stefan;
Vinken, Mathieu;
Van Haecke, Tamara;
Heimberg, Harry;
Wagner, Ernst;
Rogiers, Vera;
De Smedt, Stefaan C.;
Demeester, Joseph;
Sanders, Niek N.

Publication type:

Article

Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann–Pick Type C Disease.

Published in:

Biomedicines, 2021, v. 9, n. 12, p. 1864, doi. 10.3390/biomedicines9121864

By:

Van Hoecke, Lien;
Van Cauwenberghe, Caroline;
Börger, Verena;
Bruggeman, Arnout;
Castelein, Jonas;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Dittrich, Robin;
Claeys, Wouter;
Xie, Junhua;
Giebel, Bernd;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Special delEVery: Extracellular Vesicles as Promising Delivery Platform to the Brain.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1734, doi. 10.3390/biomedicines9111734

By:

Pauwels, Marie J.;
Vandendriessche, Charysse;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Free complement and complement containing extracellular vesicles as potential biomarkers for neuroinflammatory and neurodegenerative disorders.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2022.1055050

By:

Burgelman, Marlies;
Dujardin, Pieter;
Vandendriessche, Charysse;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 4, p. 1, doi. 10.15252/emmm.201708300

By:

Steeland, Sophie;
Gorlé, Nina;
Vandendriessche, Charysse;
Balusu, Sriram;
Brkic, Marjana;
Van Cauwenberghe, Caroline;
Van Imschoot, Griet;
Van Wonterghem, Elien;
De Rycke, Riet;
Kremer, Anneke;
Lippens, Saskia;
Stopa, Edward;
Johanson, Conrad E.;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 10, p. 1162, doi. 10.15252/emmm.201606271

By:

Balusu, Sriram;
Van Wonterghem, Elien;
De Rycke, Riet;
Raemdonck, Koen;
Stremersch, Stephan;
Gevaert, Kris;
Brkic, Marjana;
Demeestere, Delphine;
Vanhooren, Valerie;
Hendrix, An;
Libert, Claude;
Vandenbroucke, Roosmarijn E

Publication type:

Article

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 8, p. 1004, doi. 10.15252/emmm.201405010

By:

Puimège, Leen;
Van Hauwermeiren, Filip;
Steeland, Sophie;
Van Ryckeghem, Sara;
Vandewalle, Jolien;
Lodens, Sofie;
Dejager, Lien;
Vandevyver, Sofie;
Staelens, Jan;
Timmermans, Steven;
Vandenbroucke, Roosmarijn E;
Libert, Claude

Publication type:

Article

An acute phase protein ready to go therapeutic for sepsis.

Published in:

EMBO Molecular Medicine, 2014, v. 6, n. 1, p. 2, doi. 10.1002/emmm.201303524

By:

Vandevyver, Sofie;
Dejager, Lien;
Vandenbroucke, Roosmarijn E;
Libert, Claude

Publication type:

Article

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 7, p. 932, doi. 10.1002/emmm.201202100

By:

Vandenbroucke, Roosmarijn E.;
Dejonckheere, Eline;
Van Hauwermeiren, Filip;
Lodens, Sofie;
De Rycke, Riet;
Van Wonterghem, Elien;
Staes, An;
Gevaert, Kris;
López‐Otin, Carlos;
Libert, Claude

Publication type:

Article

The first MMP in sepsis.

Published in:

EMBO Molecular Medicine, 2011, v. 3, n. 7, p. 367, doi. 10.1002/emmm.201100146

By:

Vandenbroucke, Roosmarijn E.;
Dejager, Lien;
Libert, Claude

Publication type:

Article

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology.

Published in:

EMBO Journal, 2023, v. 42, n. 17, p. 1, doi. 10.15252/embj.2022111515

By:

Xie, Junhua;
Bruggeman, Arnout;
De Nolf, Clint;
Vandendriessche, Charysse;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Vereecke, Lars;
Vandenbroucke, Roosmarijn E

Publication type:

Article

Choroid plexus‐derived miR‐204 regulates the number of quiescent neural stem cells in the adult brain.

Published in:

EMBO Journal, 2019, v. 38, n. 17, p. N.PAG, doi. 10.15252/embj.2018100481

By:

Lepko, Tjasa;
Pusch, Melanie;
Müller, Tamara;
Schulte, Dorothea;
Ehses, Janina;
Kiebler, Michael;
Hasler, Julia;
Huttner, Hagen B;
Vandenbroucke, Roosmarijn E;
Vandendriessche, Charysse;
Modic, Miha;
Martin‐Villalba, Ana;
Zhao, Sheng;
LLorens‐Bobadilla, Enric;
Schneider, Anja;
Fischer, Andre;
Breunig, Christopher T;
Stricker, Stefan H;
Götz, Magdalena;
Ninkovic, Jovica

Publication type:

Article

Monitoring ALS1 and ALS3 Gene Expression During InÂ Vitro Candida albicans Biofilm Formation Under Continuous Flow Conditions.

Published in:

Mycopathologia, 2009, v. 167, n. 1, p. 9, doi. 10.1007/s11046-008-9148-6

By:

Heleen Nailis;
Roosmarijn Vandenbroucke;
Kelly Tilleman;
Dieter Deforce;
Hans Nelis;
Tom Coenye

Publication type:

Article

A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice.

Published in:

Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02574

By:

Vandewalle, Jolien;
Steeland, Sophie;
Van Ryckeghem, Sara;
Eggermont, Melanie;
Van Wonterghem, Elien;
Vandenbroucke, Roosmarijn E.;
Libert, Claude

Publication type:

Article

Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.757482

By:

Van Hoecke, Lien;
Van Cauwenberghe, Caroline;
Dominko, Kristina;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Castelein, Jonas;
Xie, Junhua;
Claeys, Wouter;
Vandendriessche, Charysse;
Kremer, Anna;
Borghgraef, Peter;
De Rycke, Riet;
Hecimovic, Silva;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/620581

By:

Brkic, Marjana;
Balusu, Sriram;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/108617

By:

De Groef, Lies;
Salinas-Navarro, Manuel;
Van Imschoot, Griet;
Libert, Claude;
Vandenbroucke, Roosmarijn E.;
Moons, Lieve

Publication type:

Article

Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 37, p. 12766, doi. 10.1523/JNEUROSCI.0006-15.2015

By:

Brkic, Marjana;
Balusu, Sriram;
Van Wonterghem, Elien;
Gorlé, Nina;
Benilova, Iryna;
Kremer, Anna;
Van Hove, Inge;
Moons, Lieve;
De Strooper, Bart;
Kanazir, Selma;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Biodegradable Dextran Nanogels for RNA Interference: Focusing on Endosomal Escape and Intracellular siRNA Delivery.

Published in:

Advanced Functional Materials, 2009, v. 19, n. 9, p. 1406, doi. 10.1002/adfm.200801795

By:

Raemdonck, Koen;
Naeye, Broes;
Buyens, Kevin;
Vandenbroucke, Roosmarijn E.;
Høgset, Anders;
Demeester, Joseph;
De Smedt, Stefaan C.

Publication type:

Article

Evaluation of Digitally Encoded Layer-by-layer Coated Microparticles as Cell Carriers.

Published in:

Advanced Functional Materials, 2008, v. 18, n. 18, p. 2716, doi. 10.1002/adfm.200800255

By:

Fayazpour, Farzaneh;
Lucas, Bart;
Vandenbroucke, Roosmarijn E.;
Derveaux, Stefaan;
Tavernier, Jan;
Lievens, Sam;
Demeester, Joseph;
De Smedt, Stefaan C.

Publication type:

Article

Dextran Microgels for Time-Controlled Delivery of siRNA.

Published in:

Advanced Functional Materials, 2008, v. 18, n. 7, p. 993, doi. 10.1002/adfm.200701039

By:

Raemdonck, Koen;
Van Thienen, Tinneke G.;
Vandenbroucke, Roosmarijn E.;
Sanders, Niek N.;
Demeester, Joseph;
De Smedt, Stefaan C.

Publication type:

Article

Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01747-6

By:

Van Hoecke, Lien;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

The N‐terminal p.(Ser38Cys) TIMP3 mutation underlying Sorsby fundus dystrophy is a founder mutation disrupting an intramolecular disulfide bond.

Published in:

Human Mutation, 2019, v. 40, n. 5, p. 539, doi. 10.1002/humu.23713

By:

Naessens, Sarah;
Zaeytijd, Julie;
Syx, Delfien;
Vandenbroucke, Roosmarijn E.;
Smeets, Frédéric;
Cauwenbergh, Caroline;
Leroy, Bart P.;
Peelman, Frank;
Coppieters, Frauke

Publication type:

Article

Is there new hope for therapeutic matrix metalloproteinase inhibition?

Published in:

Nature Reviews Drug Discovery, 2014, v. 13, n. 12, p. 904, doi. 10.1038/nrd4390

By:

Vandenbroucke, Roosmarijn E.;
Libert, Claude

Publication type:

Article

Proteomic comparison between non‐purified cerebrospinal fluid and cerebrospinal fluid‐derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia.

Published in:

Journal of Extracellular Vesicles, 2023, v. 12, n. 12, p. 1, doi. 10.1002/jev2.12383

By:

Hirschberg, Yael;
Valle‐Tamayo, Natalia;
Dols‐Icardo, Oriol;
Engelborghs, Sebastiaan;
Buelens, Bart;
Vandenbroucke, Roosmarijn E.;
Vermeiren, Yannick;
Boonen, Kurt;
Mertens, Inge

Publication type:

Article

Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-52900-4

By:

Delvaeye, Tinneke;
De Smet, Maarten A. J.;
Verwaerde, Stijn;
Decrock, Elke;
Czekaj, Aleksandra;
Vandenbroucke, Roosmarijn E.;
Lemeire, Kelly;
Gonçalves, Amanda;
Declercq, Wim;
Vandenabeele, Peter;
Krysko, Dmitri V.;
Leybaert, Luc

Publication type:

Article

Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.

Published in:

Cellular & Molecular Life Sciences, 2010, v. 67, n. 6, p. 907, doi. 10.1007/s00018-009-0220-2

By:

Vinken, Mathieu;
Decrock, Elke;
De Vuyst, Elke;
De Bock, Marijke;
Vandenbroucke, Roosmarijn E.;
De Geest, Bruno G.;
Demeester, Joseph;
Sanders, Niek N.;
Vanhaecke, Tamara;
Leybaert, Luc;
Rogiers, Vera

Publication type:

Article

Low-grade peripheral inflammation affects brain pathology in the App<sup>NL-G-F</sup>mouse model of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01253-z

By:

Xie, Junhua;
Gorlé, Nina;
Vandendriessche, Charysse;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Van Cauwenberghe, Caroline;
Parthoens, Eef;
Van Hamme, Evelien;
Lippens, Saskia;
Van Hoecke, Lien;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Importance of extracellular vesicle secretion at the blood–cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01245-z

By:

Vandendriessche, Charysse;
Balusu, Sriram;
Van Cauwenberghe, Caroline;
Brkic, Marjana;
Pauwels, Marie;
Plehiers, Nele;
Bruggeman, Arnout;
Dujardin, Pieter;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Hendrix, An;
Baeke, Femke;
De Rycke, Riet;
Gevaert, Kris;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

Alzheimer's Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APP NL-G-F Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry.

Published in:

Biology (2079-7737), 2023, v. 12, n. 6, p. 857, doi. 10.3390/biology12060857

By:

Hobin, Kasper;
Costas-Rodríguez, Marta;
Van Wonterghem, Elien;
Vandenbroucke, Roosmarijn E.;
Vanhaecke, Frank

Publication type:

Article

Corrigendum: The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis.

Published in:

2025

By:

Van Gaever, Femke;
Mingneau, Fleur;
Vanherle, Sam;
Driege, Yasmine;
Haegman, Mira;
Van Wonterghem, Elien;
Xie, Junhua;
Vandenbroucke, Roosmarijn E.;
Hendriks, Jerome J. A.;
Beyaert, Rudi;
Staal, Jens

Publication type:

Correction Notice

The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1500697

By:

Van Gaever, Femke;
Mingneau, Fleur;
Vanherle, Sam;
Driege, Yasmine;
Haegman, Mira;
Van Wonterghem, Elien;
Xie, Junhua;
Vandenbroucke, Roosmarijn E.;
Hendriks, Jerome J. A.;
Beyaert, Rudi;
Staal, Jens

Publication type:

Article

The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1500697

By:

Van Gaever, Femke;
Mingneau, Fleur;
Vanherle, Sam;
Driege, Yasmine;
Haegman, Mira;
Van Wonterghem, Elien;
Xie, Junhua;
Vandenbroucke, Roosmarijn E.;
Hendriks, Jerome J. A.;
Beyaert, Rudi;
Staal, Jens

Publication type:

Article

Can Ultrasound Solve the Transport Barrier of the Neural Retina?

Published in:

Pharmaceutical Research, 2008, v. 25, n. 11, p. 2657, doi. 10.1007/s11095-008-9684-2

By:

Liesbeth Peeters;
Ine Lentacker;
Roosmarijn Vandenbroucke;
Bart Lucas;
Joseph Demeester;
Niek Sanders;
Stefaan De Smedt

Publication type:

Article

Gastric Helicobacter suis Infection Partially Protects against Neurotoxicity in A 6-OHDA Parkinson's Disease Mouse Model.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11328, doi. 10.3390/ijms222111328

By:

Berlamont, Helena;
Bruggeman, Arnout;
Bauwens, Eva;
Vandendriessche, Charysse;
Clarebout, Elien;
Xie, Junhua;
De Bruyckere, Sofie;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Ducatelle, Richard;
Santens, Patrick;
Smet, Annemieke;
Haesebrouck, Freddy;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

A New Venue of TNF Targeting.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 5, p. 1442, doi. 10.3390/ijms19051442

By:

Steeland, Sophie;
Libert, Claude;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 11, p. 1825, doi. 10.3390/ijms17111825

By:

Van Hove, Inge;
Lefevere, Evy;
De Groef, Lies;
Sergeys, Jurgen;
Salinas-Navarro, Manuel;
Libert, Claude;
Vandenbroucke, Roosmarijn;
Moons, Lieve

Publication type:

Article

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability.

Published in:

Nature Communications, 2016, v. 7, n. 9, p. 12982, doi. 10.1038/ncomms12982

By:

Xiong, Ranhua;
Vandenbroucke, Roosmarijn E.;
Broos, Katleen;
Brans, Toon;
Van Wonterghem, Elien;
Libert, Claude;
Demeester, Jo;
De Smedt, Stefaan C.;
Braeckmans, Kevin

Publication type:

Article

A new angle on blood–CNS interfaces: A role for connexins?

Published in:

FEBS Letters, 2014, v. 588, n. 8, p. 1259, doi. 10.1016/j.febslet.2014.02.060

By:

De Bock, Marijke;
Vandenbroucke, Roosmarijn E.;
Decrock, Elke;
Culot, Maxime;
Cecchelli, Romeo;
Leybaert, Luc

Publication type:

Article

Topical imiquimod yields systemic effects due to unintended oral uptake.

Published in:

Scientific Reports, 2016, p. 20134, doi. 10.1038/srep20134

By:

Grine, Lynda;
Steeland, Sophie;
Van Ryckeghem, Sara;
Ballegeer, Marlies;
Lienenklaus, Stefan;
Weiss, Siegfried;
Sanders, Niek N.;
Vandenbroucke, Roosmarijn E.;
Libert, Claude

Publication type:

Article

Inflammasome signaling is dispensable for ß-amyloidinduced neuropathology in preclinical models of Alzheimer's disease.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1323409

By:

Srinivasan, Sahana;
Kancheva, Daliya;
De Ren, Sofie;
Takashi Saito;
Jans, Maude;
Boone, Fleur;
Vandendriessche, Charysse;
Paesmans, Ine;
Maurin, Hervé;
Vandenbroucke, Roosmarijn E.;
Hoste, Esther;
Voet, Sofie;
Scheyltjens, Isabelle;
Pavie, Benjamin;
Lippens, Saskia;
Schwabenland, Marius;
Prinz, Marco;
Takaomi Saido;
Bottelbergs, Astrid;
Movahedi, Kiavash

Publication type:

Article

Limitations of PLX3397 as a microglial investigational tool: peripheral and off-target effects dictate the response to inflammation.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1283711

By:

Claeys, Wouter;
Verhaege, Daan;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Van Acker, Lore;
Amelinck, Laura;
De Ponti, Federico F.;
Scott, Charlotte;
Geerts, Anja;
Van Steenkiste, Christophe;
Van Hoecke, Lien;
Vandenbroucke, Roosmarijn E.

Publication type:

Article