Works by Vandenberg, Jamie I.

Results: 59

Mapping the sequence of conformational changes underlying selectivity filter gating in the Kv11.1 potassium channel.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 1, p. 35, doi. 10.1038/nsmb.1966

By:

Wang, David T;
Hill, Adam P;
Mann, Stefan A;
Tan, Peter S;
Vandenberg, Jamie I

Publication type:

Article

Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo.

Published in:

Basic Research in Cardiology, 2002, v. 97, n. 5, p. 348, doi. 10.1007/s00395-002-0360-0

By:

Zhao, Jing;
Pettigrew, Gavin J.;
Thomas, Joan;
Vandenberg, Jamie I.;
Delriviere, Luc;
Bolton, Eleanor M.;
Carmichael, Andrew;
Martin, Jody L.;
Marber, Michael S.;
Lever, Andrew M. L.

Publication type:

Article

Molecular basis of slow activation of the human ether-á-go-go related gene potassium channel.

Published in:

Journal of Physiology, 2004, v. 558, n. 2, p. 417, doi. 10.1113/jphysiol.2004.062588

By:

Subbiah, Rajesh N.;
Clarke, Catherine E.;
Smith, David J.;
Zhao, JingTing;
Campbell, Terence J.;
Vandenberg, Jamie I.

Publication type:

Article

Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte.

Published in:

Journal of Physiology, 2004, v. 555, n. 1, p. 61, doi. 10.1113/jphysiol.2003.056846

By:

Martinez-Pinna, Juan;
Tolhurst, Gwen;
Gurung, Iman S.;
Vandenberg, Jamie I.;
Mahaut-Smith, Martyn P.

Publication type:

Article

Electrogram prolongation and nifedipine‐suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.

Published in:

Journal of Physiology, 2003, v. 552, n. 2, p. 535, doi. 10.1113/jphysiol.2003.048249

By:

Balasubramaniam, Richard;
Grace, Andrew A.;
Saumarez, Richard C.;
Vandenberg, Jamie I.;
Huang, Christopher L.‐H.

Publication type:

Article

Electrogram prolongation and nifedipine‐suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.

Published in:

Journal of Physiology, 2003, v. 552, n. 2, p. 535, doi. 10.1113/jphysiol.2003.048249

By:

Balasubramaniam, Richard;
Grace, Andrew A.;
Saumarez, Richard C.;
Vandenberg, Jamie I.;
Huang, Christopher L.‐H.

Publication type:

Article

Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.

Published in:

Journal of Physiology, 2003, v. 552, n. 2, p. 535, doi. 10.1113/jphysiol.2003.048249

By:

Balasubramaniam, Richard;
Grace, Andrew A.;
Saumarez, Richard C.;
Vandenberg, Jamie I.;
Huang, Christopher L.-H.

Publication type:

Article

Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.

Published in:

Journal of Physiology, 2003, v. 551, n. 1, p. 253, doi. 10.1111/j.1469-7793.2003.00253.x

By:

Lu, Yu;
Mahaut-Smith, Martyn P.;
Huang, Christopher L.-H.;
Vandenberg, Jamie I.

Publication type:

Article

Effects of premature stimulation on HERG K+ channels.

Published in:

Journal of Physiology, 2001, v. 537, n. 3, p. 843, doi. 10.1111/j.1469-7793.2001.00843.x

By:

Martyn, Yu Lu;
Mahaut-Smith, P.;
Varghese, Anthony;
Huang, Christopher L.-H.;
Kemp, Paul R.;
Vandenberg, Jamie I.

Publication type:

Article

The sodium channel β-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart.

Published in:

Journal of Physiology, 2001, v. 537, n. 3, p. 693, doi. 10.1111/j.1469-7793.2001.00693.x

By:

Fahmi, Ahmed I.;
Patel, Manoj;
Stevens, Edward B.;
Fowden, Abigail L.;
John, James Edward;
Lee, Kevin;
Pinnock, Robert;
Morgan, Kevin;
Jackson, Antony P.;
Vandenberg, Jamie I.

Publication type:

Article

Normal conduction of surface action potentials in detubulated amphibian skeletal muscle fibres.

Published in:

Journal of Physiology, 2001, v. 535, n. 2, p. 579, doi. 10.1111/j.1469-7793.2001.t01-1-00579.x

By:

Sheikh, Samir Majid;
Skepper, Jeremy N.;
Chawla, Sangeeta;
Vandenberg, Jamie I.;
Elneil, Suzy;
Huang, Christopher L.-H.

Publication type:

Article

Arrhythmogenic effects of ultra-long and bistable cardiac action potentials.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.pcbi.1008683

By:

Heitmann, Stewart;
Shpak, Anton;
Vandenberg, Jamie I.;
Hill, Adam P.

Publication type:

Article

LETTER TO THE EDITOR.

Published in:

2005

By:

Subbiah, Rajesh N.;
Campbell, Terence J.;
Vandenberg, Jamie I.

Publication type:

Letter

INHERITED CARDIAC ARRHYTHMIA SYNDROMES: WHAT HAVE THEY TAUGHT US ABOUT ARRHYTHMIAS AND ANTI-ARRHYTHMIC THERAPY?

Published in:

Clinical & Experimental Pharmacology & Physiology, 2004, v. 31, n. 12, p. 906, doi. 10.1111/j.1440-1681.2004.04132.x

By:

Subbiah, Rajesh N.;
Campbell, Terence J.;
Vandenberg, Jamie I.

Publication type:

Article

Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03405-5

By:

Thorpe, Jordan;
Perry, Matthew D.;
Contreras, Osvaldo;
Hurley, Emily;
Parker, George;
Harvey, Richard P.;
Hill, Adam P.;
Vandenberg, Jamie I.

Publication type:

Article

C-Terminal β9-Strand of the Cyclic Nucleotide-Binding Homology Domain Stabilizes Activated States of Kv11.1 Channels.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077032

By:

Ng, Chai Ann;
Ke, Ying;
Perry, Matthew D.;
Tan, Peter S.;
Hill, Adam P.;
Vandenberg, Jamie I.

Publication type:

Article

The Schizophrenia-Associated Kv11.1-3.1 Isoform Results in Reduced Current Accumulation during Repetitive Brief Depolarizations.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045624

By:

Heide, Juliane;
Mann, Stefan A.;
Vandenberg, Jamie I.;
Brown, Jon T.

Publication type:

Article

The S4-S5 Linker Acts as a Signal Integrator for hERG K+ Channel Activation and Deactivation Gating.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031640

By:

Chai, Ann Ng;
Perry, Matthew D.;
Tan, Peter S.;
Hill, Adam P.;
Kuchel, Philip W.;
Vandenberg, Jamie I.

Publication type:

Article

The N--Terminal Tail of hERG Contains an Amphipathic α-- Helix That Regulates Channel Deactivation.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016191

By:

Chai Ann Ng;
Hunter, Mark J.;
Perry, Matthew D.;
Mobli, Mehdi;
Ke, Ying;
Kuchel, Philip W.;
King, Glenn F.;
Stock, Daniela;
Vandenberg, Jamie I.

Publication type:

Article

Cell swelling and ion transport pathways in cardiac myocytes.

Published in:

Cardiovascular Research, 1996, v. 32, n. 1, p. 85, doi. 10.1016/S0008-6363(96)00048-X

By:

Vandenberg, Jamie I.;
Rees, Siân A.;
Wright, Anthony R.;
Powell, Trevor

Publication type:

Article

Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 7, p. 1072, doi. 10.1093/hmg/ddac261

By:

Copier, Jaël S;
Bootsma, Marianne;
Ng, Chai A;
Wilde, Arthur A M;
Bertels, Robin A;
Bikker, Hennie;
Christiaans, Imke;
Crabben, Saskia N van der;
Hol, Janna A;
Koopmann, Tamara T;
Knijnenburg, Jeroen;
Lommerse, Aafke A J;
Smagt, Jasper J van der;
Bezzina, Connie R;
Vandenberg, Jamie I;
Verkerk, Arie O;
Barge-Schaapveld, Daniela Q C M;
Lodder, Elisabeth M

Publication type:

Article

The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review.

Published in:

Annals of Noninvasive Electrocardiology, 2023, v. 28, n. 1, p. 1, doi. 10.1111/anec.13015

By:

Tardo, Daniel T.;
Peck, Matthew;
Subbiah, Rajesh N.;
Vandenberg, Jamie I.;
Hill, Adam. P.

Publication type:

Article

Action potential shortening through the putative β4-adrenoceptor in ferret ventricle: comparison with β1- and β2-adrenoceptor-mediated effects.

Published in:

British Journal of Pharmacology, 1998, v. 124, n. 7, p. 1341, doi. 10.1038/sj.bjp.0702013

By:

Lowe, Martin D.;
Grace, Andrew A.;
Vandenberg, Jamie I.;
Kaumann, Alberto J.

Publication type:

Article

BIOPHYSCHEM2011: A Joint Meeting of the Australian Society for Biophysics and the RACI Physical Chemistry Division.

Published in:

Australian Journal of Chemistry, 2012, v. 65, n. 5, p. 18, doi. 10.1071/CH12213

By:

Trevitt, Adam J.;
Reimers, Jeffrey R.;
Clarke, Ronald J.;
Vandenberg, Jamie I.

Publication type:

Article

Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin

Published in:

FEBS Letters, 2003, v. 539, n. 1-3, p. 138, doi. 10.1016/S0014-5793(03)00216-3

By:

Torres, Allan M.;
Bansal, Paramjit;
Alewood, Paul F.;
Bursill, Jane A.;
Kuchel, Philip W.;
Vandenberg, Jamie I.

Publication type:

Article

In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details.

Published in:

Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00934

By:

Lee, William;
Windley, Monique J.;
Vandenberg, Jamie I.;
Hill, Adam P.

Publication type:

Article

Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics.

Published in:

Journal of Physiology, 2018, v. 596, n. 10, p. 1813, doi. 10.1113/JP275733

By:

Beattie, Kylie A.;
Hill, Adam P.;
Bardenet, Rémi;
Cui, Yi;
Vandenberg, Jamie I.;
Gavaghan, David J.;
Boer, Teun P.;
Mirams, Gary R.

Publication type:

Article

Never at rest: insights into the conformational dynamics of ion channels from cryo‐electron microscopy.

Published in:

Journal of Physiology, 2018, v. 596, n. 7, p. 1107, doi. 10.1113/JP274888

By:

Hunter, Mark J.;
Lau, Carus;
Stewart, Alastair;
Vandenberg, Jamie I.;
Perozo, Eduardo

Publication type:

Article

TECRL: connecting sequence to consequence for a new sudden cardiac death gene.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 12, p. 1364, doi. 10.15252/emmm.201606967

By:

Perry, Matthew D;
Vandenberg, Jamie I

Publication type:

Article

The effect of heptanol on the electrical and contractile function of the isolated, perfused rabbit heart.

Published in:

Pflügers Archiv: European Journal of Physiology, 2000, v. 440, n. 2, p. 275, doi. 10.1007/s004240000264

By:

Keevil, Victoria L.;
Huang, Christopher L.-H.;
Chau, P.-L.;
Sayeed, Rana A.;
Vandenberg, Jamie I.

Publication type:

Article

Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01035

By:

Munawar, Saba;
Windley, Monique J.;
Tse, Edwin G.;
Todd, Matthew H.;
Hill, Adam P.;
Vandenberg, Jamie I.;
Jabeen, Ishrat

Publication type:

Article

Structure of the pore-helix of the hERG K+ channel.

Published in:

European Biophysics Journal, 2009, v. 39, n. 1, p. 111, doi. 10.1007/s00249-009-0433-1

By:

Pages, Guilhem;
Torres, Allan M.;
Pengchu Ju;
Bansal, Paramjit S.;
Alewood, Paul F.;
Kuchel, Philip W.;
Vandenberg, Jamie I.

Publication type:

Article

Proteins, membranes and cells: the structure–function nexus—ASB 2008.

Published in:

2009

By:

Vandenberg, Jamie I.;
Kuchel, Philip W.

Publication type:

Editorial

The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics.

Published in:

2004

By:

Vandenberg, Jamie I.;
Torres, Allan M.;
Campbell, Terence J.;
Kuchel, Philip W.

Publication type:

Erratum

The HERG K[sup +] channel: progress in understanding the molecular basis of its unusual gating kinetics.

Published in:

European Biophysics Journal, 2004, v. 33, n. 2, p. 89, doi. 10.1007/s00249-003-0338-3

By:

Vandenberg, Jamie I.;
Torres, Allan M.;
Campbell, Terence J.;
Kuchel, Philip W.

Publication type:

Article

Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2631, doi. 10.1111/bph.15757

By:

TeBay, Clifford;
McArthur, Jeffrey R.;
Mangala, Melissa;
Kerr, Nicholas;
Heitmann, Stewart;
Perry, Matthew D.;
Windley, Monique J.;
Vandenberg, Jamie I.;
Hill, Adam P.

Publication type:

Article

Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2.

Published in:

Nature Communications, 2014, v. 5, n. 9, p. 5069, doi. 10.1038/ncomms6069

By:

Sadrieh, Arash;
Domanski, Luke;
Pitt-Francis, Joe;
Mann, Stefan A;
Hodkinson, Emily C;
Ng, Chai-Ann;
Perry, Matthew D;
Taylor, John A;
Gavaghan, David;
Subbiah, Rajesh N;
Vandenberg, Jamie I;
Hill, Adam P

Publication type:

Article

Heritability of ECG Biomarkers in the Netherlands Twin Registry Measured from Holter ECGs.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00154

By:

Hodkinson, Emily C.;
Neijts, Melanie;
Sadrieh, Arash;
Imtiaz, Mohammad S.;
Baumert, Mathias;
Subbiah, Rajesh N.;
Hayward, Christopher S.;
Boomsma, Dorret;
Willemsen, Gonneke;
Vandenberg, Jamie I.;
Hill, Adam P.;
De Geus, Eco

Publication type:

Article

yin and yang of Tbx5 variant effects on sodium channel function.

Published in:

Cardiovascular Research, 2022, v. 118, n. 4, p. 929, doi. 10.1093/cvr/cvac015

By:

Kerr, Nicholas P;
Vandenberg, Jamie I

Publication type:

Article

Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events.

Published in:

Cardiovascular Research, 2021, v. 117, n. 10, p. 2216, doi. 10.1093/cvr/cvaa280

By:

Ballouz, Sara;
Mangala, Melissa M;
Perry, Matthew D;
Heitmann, Stewart;
Gillis, Jesse A;
Hill, Adam P;
Vandenberg, Jamie I

Publication type:

Article

Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.

Published in:

Cardiovascular Research, 2020, v. 116, n. 8, p. 1434, doi. 10.1093/cvr/cvz247

By:

Perry, Matthew D;
Ng, Chai-Ann;
Mangala, Melissa M;
Ng, Timothy Y M;
Hines, Adam D;
Liang, Whitney;
Xu, Michelle J O;
Hill, Adam P;
Vandenberg, Jamie I

Publication type:

Article

Nobel Prizes for magnetic resonance imaging and channel proteins.

Published in:

Medical Journal of Australia, 2003, v. 179, n. 11, p. 611, doi. 10.5694/j.1326-5377.2003.tb05718.x

By:

Vandenberg, Jamie I;
Kuchel, Philip W

Publication type:

Article

Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology.

Published in:

Biology Methods & Protocols, 2021, v. 6, n. 1, p. 1, doi. 10.1093/biomethods/bpab003

By:

Ng, Chai-Ann;
Farr, Jessica;
Young, Paul;
Windley, Monique J;
Perry, Matthew D;
Hill, Adam P;
Vandenberg, Jamie I

Publication type:

Article

Not All hERG Pore Domain Mutations Have a Severe Phenotype: G584S Has an Inactivation Gating Defect with Mild Phenotype Compared to G572S, Which Has a Dominant Negative Trafficking Defect and a Severe Phenotype.

Published in:

Journal of Cardiovascular Electrophysiology, 2009, v. 20, n. 8, p. 923, doi. 10.1111/j.1540-8167.2009.01468.x

By:

ZHAO, JING TING;
HILL, ADAM P.;
VARGHESE, ANTHONY;
COOPER, ANTONY A.;
SWAN, HEIKKI;
LAITINEN‐FORSBLOM, PÄIVI J.;
REES, MARK I.;
SKINNER, JONATHAN R.;
CAMPBELL, TERENCE J.;
VANDENBERG, JAMIE I.

Publication type:

Article

Potassium channels in the heart: structure, function and regulation.

Published in:

Journal of Physiology, 2017, v. 595, n. 7, p. 2209, doi. 10.1113/JP272864

By:

Grandi, Eleonora;
Sanguinetti, Michael C.;
Bartos, Daniel C.;
Bers, Donald M.;
Chen‐Izu, Ye;
Chiamvimonvat, Nipavan;
Colecraft, Henry M.;
Delisle, Brian P.;
Heijman, Jordi;
Navedo, Manuel F.;
Noskov, Sergei;
Proenza, Catherine;
Vandenberg, Jamie I.;
Yarov‐Yarovoy, Vladimir

Publication type:

Article

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics.

Published in:

Journal of Physiology, 2017, v. 595, n. 7, p. 2229, doi. 10.1113/JP272883

By:

Chiamvimonvat, Nipavan;
Chen‐Izu, Ye;
Clancy, Colleen E.;
Deschenes, Isabelle;
Dobrev, Dobromir;
Heijman, Jordi;
Izu, Leighton;
Qu, Zhilin;
Ripplinger, Crystal M.;
Vandenberg, Jamie I.;
Weiss, James N.;
Koren, Gideon;
Banyasz, Tamas;
Grandi, Eleonora;
Sanguinetti, Michael C.;
Bers, Donald M.;
Nerbonne, Jeanne M.

Publication type:

Article

Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century.

Published in:

Journal of Physiology, 2016, v. 594, n. 23, p. 6893, doi. 10.1113/JP272015

By:

Hill, Adam P.;
Perry, Matthew D.;
Abi‐Gerges, Najah;
Couderc, Jean‐Philippe;
Fermini, Bernard;
Hancox, Jules C.;
Knollmann, Bjorn C.;
Mirams, Gary R.;
Skinner, Jon;
Zareba, Wojciech;
Vandenberg, Jamie I.

Publication type:

Article

Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations.

Published in:

Journal of Physiology, 2016, v. 594, n. 14, p. 4031, doi. 10.1113/JP271805

By:

Perry, Matthew D.;
Ng, Chai Ann;
Phan, Kevin;
David, Erikka;
Steer, Kieran;
Hunter, Mark J.;
Mann, Stefan A.;
Imtiaz, Mohammad;
Hill, Adam P.;
Ke, Ying;
Vandenberg, Jamie I.

Publication type:

Article

An 'alternans' way to quantify arrhythmogenic substrates.

Published in:

Journal of Physiology, 2016, v. 594, n. 9, p. 2375, doi. 10.1113/JP271838

By:

Vandenberg, Jamie I.;
Hill, Adam P.

Publication type:

Article

Getting to the heart of hERG K+ channel gating.

Published in:

Journal of Physiology, 2015, v. 593, n. 12, p. 2575, doi. 10.1113/JP270095

By:

Perry, Matthew D.;
Ng, Chai‐Ann;
Mann, Stefan A.;
Sadrieh, Arash;
Imtiaz, Mohammad;
Hill, Adam P.;
Vandenberg, Jamie I.

Publication type:

Article