Works by Vandebriel, Rob J.

Results: 43

Towards prospective identification of respiratory sensitizers: effects of piperazine, chloramine-T, and toluene-diisocyanate in an air–liquid interface model comprising human bronchial epithelial cells.

Published in:

Archives of Toxicology, 2025, v. 99, n. 6, p. 2479, doi. 10.1007/s00204-025-04029-9

By:

Duistermaat, Evert;
de Bruijn, Véronique M. P.;
Vermeulen, Jolanda P.;
Gremmer, Eric R.;
Vandebriel, Rob J.

Publication type:

Article

Airborne particulate matter from goat farm increases acute allergic airway responses in mice.

Published in:

Inhalation Toxicology, 2020, v. 32, n. 6, p. 265, doi. 10.1080/08958378.2020.1781986

By:

Liu, Dingyu;
Wagner, James G.;
Mariman, Rob;
Harkema, Jack R.;
Gerlofs-Nijland, Miriam E.;
Pinelli, Elena;
Folkerts, Gert;
Cassee, Flemming R.;
Vandebriel, Rob J.

Publication type:

Article

Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection.

Published in:

2007

By:

Banus, Sander;
Vandebriel, Rob J.;
Pennings, Jeroen L. A.;
Gremmer, Eric R.;
Wester, Piet W.;
van Kranen, Henk J.;
Breit, Timo M.;
Demant, Peter;
Mooi, Frits R.;
Hoebee, Barbara;
Kimman, Tjeerd G.

Publication type:

Book Chapter

Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls.

Published in:

WIREs: Nanomedicine & Nanobiotechnology, 2020, v. 12, n. 5, p. 1, doi. 10.1002/wnan.1633

By:

Giannakou, Christina;
Park, Margriet V. D. Z.;
Bosselaers, Irene E. M.;
Jong, Wim H.;
Laan, Jan Willem;
Loveren, Henk;
Vandebriel, Rob J.;
Geertsma, Robert E.

Publication type:

Article

Nano(bio)Materials Do Not Affect Macrophage Phenotype—A Study Conducted by the REFINE Project.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5491, doi. 10.3390/ijms25105491

By:

David, Christopher A. W.;
Vermeulen, Jolanda P.;
Gioria, Sabrina;
Vandebriel, Rob J.;
Liptrott, Neill J.

Publication type:

Article

Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13046, doi. 10.3390/ijms232113046

By:

Jennen, Danyel G. J.;
van Herwijnen, Marcel;
Jetten, Marlon;
Vandebriel, Rob J.;
Keizers, Peter;
Geertsma, Robert E.;
de Jong, Wim H.;
Kleinjans, Jos C. S.

Publication type:

Article

Evaluation of Adverse Effects of Resorbable Hyaluronic Acid Fillers: Determination of Macrophage Responses.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7275, doi. 10.3390/ijms23137275

By:

De Jong, Wim H.;
Jennen, Danyel;
Keizers, Peter H. J.;
Hodemaekers, Hennie M.;
Vermeulen, Jolanda P.;
Bakker, Frank;
Schwillens, Paul;
van Herwijnen, Marcel;
Jetten, Marlon;
Kleinjans, Jos C. S.;
Geertsma, Robert E.;
Vandebriel, Rob J.

Publication type:

Article

Pathways Related to NLRP3 Inflammasome Activation Induced by Gold Nanorods.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5763, doi. 10.3390/ijms23105763

By:

Vandebriel, Rob J.;
Remy, Sylvie;
Vermeulen, Jolanda P.;
Hurkmans, Evelien G. E.;
Kevenaar, Kirsten;
Bastús, Neus G.;
Pelaz, Beatriz;
Soliman, Mahmoud G.;
Puntes, Victor F.;
Parak, Wolfgang J.;
Pennings, Jeroen L. A.;
Nelissen, Inge

Publication type:

Article

Impact of Differentiated Macrophage-Like Cells on the Transcriptional Toxicity Profile of CuO Nanoparticles in Co-Cultured Lung Epithelial Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 5044, doi. 10.3390/ijms22095044

By:

Hufnagel, Matthias;
Neuberger, Ronja;
Wall, Johanna;
Link, Martin;
Friesen, Alexandra;
Hartwig, Andrea;
Vandebriel, Rob J.;
Bagella, Luigi M.

Publication type:

Article

Modulation of Innate Immune Toxicity by Silver Nanoparticle Exposure and the Preventive Effects of Pterostilbene.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2536, doi. 10.3390/ijms22052536

By:

Chen, Rong-Jane;
Huang, Chiao-Ching;
Pranata, Rosita;
Lee, Yu-Hsuan;
Chen, Yu-Ying;
Wu, Yuan-Hua;
Wang, Ying-Jan;
Vandebriel, Rob J.

Publication type:

Article

Gene polymorphisms within the immune system that may underlie drug allergy.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 369, n. 1, p. 125, doi. 10.1007/s00210-003-0804-6

By:

Vandebriel, Rob J.

Publication type:

Article

Toward a mechanism-based in vitro safety test for pertussis toxin.

Published in:

Human Vaccines & Immunotherapeutics, 2014, v. 10, n. 5, p. 1, doi. 10.4161/hv.28001

By:

Vaessen, Stefan F. C.;
Bruysters, Martijn W. P.;
Vandebriel, Rob J.;
Verkoeijen, Saertje;
Bos, Rogier;
Krul, Cyrille Am;
Akkermans, Arnoud M.

Publication type:

Article

Dendritic cell-based in vitro assays for vaccine immunogenicity.

Published in:

Human Vaccines & Immunotherapeutics, 2012, v. 8, n. 9, p. 1, doi. 10.4161/hv.21350

By:

Vandebriel, Rob J.;
Hoefnagel, Marcel H. N.

Publication type:

Article

A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment.

Published in:

Nanotoxicology, 2021, v. 15, n. 3, p. 289, doi. 10.1080/17435390.2020.1851419

By:

Halappanavar, Sabina;
Ede, James D.;
Mahapatra, Indrani;
Krug, Harald F.;
Kuempel, Eileen D.;
Lynch, Iseult;
Vandebriel, Rob J.;
Shatkin, Jo Anne

Publication type:

Article

The effect of zirconium doping of cerium dioxide nanoparticles on pulmonary and cardiovascular toxicity and biodistribution in mice after inhalation.

Published in:

Nanotoxicology, 2017, v. 11, n. 6, p. 794, doi. 10.1080/17435390.2017.1357214

By:

Dekkers, Susan;
Miller, Mark R.;
Schins, Roel P. F.;
Römer, Isabella;
Russ, Mike;
Vandebriel, Rob J.;
Lynch, Iseult;
Belinga-Desaunay, Marie-France;
Valsami-Jones, Eugenia;
Connell, Shea P.;
Smith, Ian P.;
Duffin, Rodger;
Boere, John A. F.;
Heusinkveld, Harm J.;
Albrecht, Catrin;
de Jong, Wim H.;
Cassee, Flemming R.

Publication type:

Article

Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations.

Published in:

Nanotoxicology, 2016, v. 10, n. 10, p. 1515, doi. 10.1080/17435390.2016.1238113

By:

Heringa, Minne B.;
Geraets, Liesbeth;
van Eijkeren, Jan C. H.;
Vandebriel, Rob J.;
de Jong, Wim H.;
Oomen, Agnes G.

Publication type:

Article

Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0193297

By:

de Jong, Hilda J. I.;
Cohen Tervaert, Jan Willem;
Lalmohamed, Arief;
de Vries, Frank;
Vandebriel, Rob J.;
van Loveren, Henk;
Klungel, Olaf H.;
van Staa, Tjeerd P.

Publication type:

Article

Overcoming scientific barriers in the transition from in vivo to non-animal batch testing of human and veterinary vaccines.

Published in:

Expert Review of Vaccines, 2021, v. 20, n. 10, p. 1221, doi. 10.1080/14760584.2021.1977628

By:

van den Biggelaar, Robin H. G. A.;
Hoefnagel, Marcel H.N.;
Vandebriel, Rob J.;
Sloots, Arjen;
Hendriksen, Coenraad F.M.;
van Eden, Willem;
Rutten, Victor P. M. G.;
Jansen, Christine A.

Publication type:

Article

Role of chemical composition and redox modification of poorly soluble nanomaterials on their ability to enhance allergic airway sensitisation in mice.

Published in:

Particle & Fibre Toxicology, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12989-019-0320-6

By:

Dekkers, Susan;
Wagner, James G.;
Vandebriel, Rob J.;
Eldridge, Elyse A.;
Tang, Selina V. Y.;
Miller, Mark R.;
Römer, Isabella;
de Jong, Wim H.;
Harkema, Jack R.;
Cassee, Flemming R.

Publication type:

Article

The crystal structure of titanium dioxide nanoparticles influences immune activity in vitro and in vivo.

Published in:

Particle & Fibre Toxicology, 2018, v. 15, p. 1, doi. 10.1186/s12989-018-0245-5

By:

Vandebriel, Rob J.;
Vermeulen, Jolanda P.;
van Engelen, Laurens B.;
de Jong, Britt;
Verhagen, Lisa M.;
de la Fonteyne-Blankestijn, Liset J.;
Hoonakker, Marieke E.;
de Jong, Wim H.

Publication type:

Article

Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users.

Published in:

Pharmacoepidemiology & Drug Safety, 2012, v. 21, n. 8, p. 835, doi. 10.1002/pds.3291

By:

Jong, Hilda J. I.;
Vandebriel, Rob J.;
Saldi, Siti R. F.;
Dijk, Liset;
Loveren, Henk;
Cohen Tervaert, Jan Willem;
Klungel, Olaf H.

Publication type:

Article

A review of mammalian toxicity of ZnO nanoparticles.

Published in:

Nanotechnology, Science & Applications, 2012, v. 5, p. 61, doi. 10.2147/nsa.s23932

By:

Vandebriel, Rob J.;
De Jong, Wim H.

Publication type:

Article

Keratinocyte Gene Expression Profiles Discriminate Sensitizing and Irritating Compounds.

Published in:

Toxicological Sciences, 2010, v. 117, n. 1, p. 81, doi. 10.1093/toxsci/kfq182

By:

Vandebriel, Rob J.;
Pennings, Jeroen L. A.;
Baken, Kirsten A.;
Pronk, Tessa E.;
Boorsma, Andre;
Gottschalk, Ralph;
Van Loveren, Henk

Publication type:

Article

Ranking of Allergenic Potency of Rubber Chemicals in a Modified Local Lymph Node Assay.

Published in:

Toxicological Sciences, 2002, v. 66, n. 2, p. 226, doi. 10.1093/toxsci/66.2.226

By:

De Jong, Wim H.;
Van Och, François M. M.;
Jager, Constance F. Den Hartog;
Spiekstra, Sander W.;
Slob, W.;
Vandebriel, Rob J.;
Van Loveren, Henk

Publication type:

Article

Response to ‘Statins accelerate the onset of collagen type II-induced arthritis in mice’ – authors’ reply.

Published in:

Arthritis Research & Therapy, 2013, v. 15, n. 2, p. 403, doi. 10.1186/ar4170

By:

Vandebriel, Rob J;
De Jong, Hilda JI;
Gremmer, Eric R;
Klungel, Olaf H;
Cohen Tervaert, Jan-Willem;
Slob, Wout;
Van Der Laan, Jan Willem;
Van Loveren, Henk

Publication type:

Article

The Value of Organs-on-Chip for Regulatory Safety Assessment.

Published in:

Altex, 2020, v. 37, n. 2, p. 208, doi. 10.14573/altex.1910111

By:

Heringa, Minne B.;
Park, Margriet V. D. Z.;
Kienhuis, Anne S.;
Vandebriel, Rob J.

Publication type:

Article

The Use of Biomarkers of Toxicity for Integrating In Vitro Hazard Estimates Into Risk Assessment for Humans.

Published in:

Altex, 2012, v. 29, n. 4, p. 411, doi. 10.14573/altex.2012.4.411

By:

Blaauboer, Bas J.;
Boekelheide, Kim;
Clewell, Harvey J.;
Daneshian, Mardas;
Dingemans, Milou M. L.;
Goldberg, Alan M.;
Heneweer, Marjoke;
Jaworska, Joanna;
Kramer, Nynke I.;
Leist, Marcel;
Seibert, Hasso;
Testai, Emanuela;
Vandebriel, Rob J.;
Yager, James D.;
Zurlo, Joanne

Publication type:

Article

Immunotoxicity of silver nanoparticles in an intravenous 28-day repeated-dose toxicity study in rats.

Published in:

Particle & Fibre Toxicology, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1743-8977-11-21

By:

Vandebriel, Rob J.;
Tonk, Elisa C. M.;
de la Fonteyne-Blankestijn, Liset J.;
Gremmer, Eric R.;
Verharen, Henny W.;
van der Ven, Leo T.;
van Loveren, Henk;
de Jong, Wim H.

Publication type:

Article

Sub-chronic toxicity study in rats orally exposed to nanostructured silica.

Published in:

Particle & Fibre Toxicology, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1743-8977-11-8

By:

van der Zande, Meike;
Vandebriel, Rob J.;
Groot, Maria J.;
Kramer, Evelien;
Rivera, Zahira E. Herrera;
Rasmussen, Kirsten;
Ossenkoppele, Jan S.;
Tromp, Peter;
Gremmer, Eric R.;
Peters, Ruud J. B.;
Hendriksen, Peter J.;
Marvin, Hans J. P.;
Hoogenboom, Ron L. A. P;
Peijnenburg, Ad A. C. M;
Bouwmeester, Hans

Publication type:

Article

The role of Toll-like receptor-4 in pertussis vaccine-induced immunity.

Published in:

BMC Immunology, 2008, v. 9, p. 1, doi. 10.1186/1471-2172-9-21

By:

Banus, Sander;
Stenger, Rachel M.;
Gremmer, Eric R.;
Dormans, Jan A. M. A.;
Mooi, Frits R.;
Kimman, Tjeerd G.;
Vandebriel, Rob J.

Publication type:

Article

Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation.

Published in:

Critical Reviews in Toxicology, 2024, v. 54, n. 7, p. 476, doi. 10.1080/10408444.2024.2377203

By:

Vandebriel, Rob J.;
Hakkert, Betty;
Pennings, Jeroen L. A.;
Rossi, Laura H.;
Bichlmaier, Ingo;
Bil, Wieneke

Publication type:

Article

Applicability of organ-on-chip systems in toxicology and pharmacology.

Published in:

2021

By:

Schneider, Marlon R.;
Oelgeschlaeger, Michael;
Burgdorf, Tanja;
van Meer, Peter;
Theunissen, Peter;
Kienhuis, Anne S.;
Piersma, Aldert H.;
Vandebriel, Rob J.

Publication type:

Literature Review

Non-animal sensitization testing: State-of-the-art.

Published in:

Critical Reviews in Toxicology, 2010, v. 40, n. 5, p. 389, doi. 10.3109/10408440903524262

By:

Vandebriel, Rob J.;
Loveren, Henk van

Publication type:

Article

Chemical respiratory sensitization--Current status of mechanistic understanding, knowledge gaps and possible identification methods of sensitizers.

Published in:

Frontiers in Toxicology, 2024, p. 01, doi. 10.3389/ftox.2024.1331803

By:

Hargitai, Rita;
Parráková, Lucia;
Szatmári, Tünde;
Monfort-Lanzas, Pablo;
Galbiati, Valentina;
Audouze, Karine;
Jornod, Florence;
Staal, Yvonne C. M.;
Burla, Sabina;
Chary, Aline;
Gutleb, Arno C.;
Lumniczky, Katalin;
Vandebriel, Rob J.;
Gostner, Johanna M.

Publication type:

Article

Regulation of Clostridium tetani Neurotoxin Expression by Culture Conditions.

Published in:

Toxins, 2022, v. 14, n. 1, p. 31, doi. 10.3390/toxins14010031

By:

Pennings, Jeroen L. A.;
Abachin, Eric;
Esson, Raphaël;
Hodemaekers, Hennie;
Francotte, Antoine;
Claude, Jean-Baptiste;
Vanhee, Céline;
Uhlrich, Sylvie;
Vandebriel, Rob J.

Publication type:

Article

Statin Use and Markers of Immunity in the Doetinchem Cohort Study.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077587

By:

De Jong, Hilda J.I.;
Damoiseaux, Jan G.M.C.;
Vandebriel, Rob J.;
Souverein, Patrick C.;
Gremmer, Eric R.;
Wolfs, Mia;
Klungel, Olaf H.;
Van Loveren, Henk;
Cohen Tervaert, Jan Willem;
Verschuren, W.M. Monique

Publication type:

Article

Statin-Associated Polymyalgia Rheumatica. An Analysis Using WHO Global Individual Case Safety Database: A Case/Non-Case Approach.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041289

By:

de Jong, Hilda J. I.;
Saldi, Siti R. F.;
Klungel, Olaf H.;
Vandebriel, Rob J.;
Souverein, Patrick C.;
Meyboom, Ronald H. B.;
Passier, J. L. M. (Anneke);
Loveren, Henk van;
Tervaert, Jan Willem Cohen

Publication type:

Article

Toxicogenomics of Subchronic Hexachlorobenzene Exposure in Brown Norway Rats.

Published in:

Environmental Health Perspectives, 2004, v. 112, n. 7, p. 782, doi. 10.1289/ehp.112-1241993

By:

Ezendam, Janine;
Staedtler, Frank;
Pennings, Jeroen;
Vandebriel, Rob J.;
Pieters, Raymond;
Harleman, Johannes H.;
Vos, Joseph G.

Publication type:

Article

Vaccine-Induced Antibody Responses as Parameters of the Influence of Endogenous and Environmental Factors.

Published in:

Environmental Health Perspectives, 2001, v. 109, n. 8, p. 757, doi. 10.1289/ehp.01109757

By:

Loveren, Henk Van;
Van Amsterdam, Jan G.C.;
Vandebriel, Rob J.;
Kimman, Tjeerd G.;
Rümke, Hans C.;
Steerenberg, Peter S.;
Vos, Jeff G.

Publication type:

Article

A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro.

Published in:

Journal of Applied Toxicology, 2018, v. 38, n. 2, p. 160, doi. 10.1002/jat.3518

By:

Dankers, Anita C. A.;
Kuper, C. Frieke;
Boumeester, Anja J.;
Fabriek, Babs O.;
Kooter, Ingeborg M.;
Gröllers‐Mulderij, Mariska;
Tromp, Peter;
Nelissen, Inge;
Zondervan‐Van Den Beuken, Esther K.;
Vandebriel, Rob J.

Publication type:

Article

Physiologically‐Based Kinetic Modeling of Intravenously Administered Gold (Au) Nanoparticles.

Published in:

Small, 2023, v. 19, n. 21, p. 1, doi. 10.1002/smll.202207326

By:

Minnema, Jordi;
Vandebriel, Rob J;
Boer, Karin;
Klerx, Walther;
De Jong, Wim H.;
Delmaar, Christiaan J. E.

Publication type:

Article

Nanomedicinal products: a survey on specific toxicity and side effects.

Published in:

International Journal of Nanomedicine, 2017, v. 12, p. 6107, doi. 10.2147/IJN.S139687

By:

Brand, Walter;
Noorlander, Cornelle W.;
Giannakou, Christina;
De Jong, Wim H.;
Kooi, Myrna W.;
Park, Margriet V. D. Z.;
Vandebriel, Rob J.;
Bosselaers, Irene E. M.;
Scholl, Joep H. G.;
Geertsma, Robert E.

Publication type:

Article

A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements.

Published in:

International Journal of Nanomedicine, 2016, v. 11, p. 2935, doi. 10.2147/IJN.S102385

By:

Giannakou, Christina;
Park, Margriet VDZ;
de Jong, Wim H.;
van Loveren, Henk;
Vandebriel, Rob J.;
Geertsma, Robert E.

Publication type:

Article