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Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 3, p. 139, doi. 10.3390/metabo11030139
By:
- Sun, Jinny;
- Bok, Robert A.;
- DeLos Santos, Justin;
- Upadhyay, Deepti;
- DeLos Santos, Romelyn;
- Agarwal, Shubhangi;
- Van Criekinge, Mark;
- Vigneron, Daniel B.;
- Aggarwal, Rahul;
- Peehl, Donna M.;
- Kurhanewicz, John;
- Sriram, Renuka;
- Martins, Andre F.;
- Chaumeil, Myriam M.
Publication type:
Article
Clinical translation of hyperpolarized 13C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging.
Published in:
Magnetic Resonance in Medicine, 2022, v. 87, n. 1, p. 138, doi. 10.1002/mrm.28965
By:
- Qin, Hecong;
- Tang, Shuyu;
- Riselli, Andrew M.;
- Bok, Robert A.;
- Delos Santos, Romelyn;
- van Criekinge, Mark;
- Gordon, Jeremy W.;
- Aggarwal, Rahul;
- Chen, Rui;
- Goddard, Gregory;
- Zhang, Chunxin Tracy;
- Chen, Albert;
- Reed, Galen;
- Ruscitto, Daniel M.;
- Slater, James;
- Sriram, Renuka;
- Larson, Peder E. Z.;
- Vigneron, Daniel B.;
- Kurhanewicz, John
Publication type:
Article
Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13C MR EPSI studies of liver tumors.
Published in:
Magnetic Resonance in Medicine, 2021, v. 86, n. 5, p. 2402, doi. 10.1002/mrm.28901
By:
- Lee, Philip M.;
- Chen, Hsin‐Yu;
- Gordon, Jeremy W.;
- Zhu, Zihan;
- Larson, Peder E.Z.;
- Dwork, Nicholas;
- Van Criekinge, Mark;
- Carvajal, Lucas;
- Ohliger, Michael A.;
- Wang, Zhen J.;
- Xu, Duan;
- Kurhanewicz, John;
- Bok, Robert A.;
- Aggarwal, Rahul;
- Munster, Pamela N.;
- Vigneron, Daniel B.
Publication type:
Article
Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
Published in:
Magnetic Resonance in Medicine, 2019, v. 81, n. 4, p. 2702, doi. 10.1002/mrm.27549
By:
- Gordon, Jeremy W.;
- Chen, Hsin‐Yu;
- Autry, Adam;
- Park, Ilwoo;
- Van Criekinge, Mark;
- Mammoli, Daniele;
- Milshteyn, Eugene;
- Bok, Robert;
- Xu, Duan;
- Li, Yan;
- Aggarwal, Rahul;
- Chang, Susan;
- Slater, James B.;
- Ferrone, Marcus;
- Nelson, Sarah;
- Kurhanewicz, John;
- Larson, Peder E.Z.;
- Vigneron, Daniel B.
Publication type:
Article
Technique development of 3D dynamic CS‐EPSI for hyperpolarized 13C pyruvate MR molecular imaging of human prostate cancer.
Published in:
Magnetic Resonance in Medicine, 2018, v. 80, n. 5, p. 2062, doi. 10.1002/mrm.27179
By:
- Chen, Hsin‐Yu;
- Larson, Peder E. Z.;
- Gordon, Jeremy W.;
- Bok, Robert A.;
- Ferrone, Marcus;
- van Criekinge, Mark;
- Carvajal, Lucas;
- Cao, Peng;
- Pauly, John M.;
- Kerr, Adam B.;
- Park, Ilwoo;
- Slater, James B.;
- Nelson, Sarah J.;
- Munster, Pamela N.;
- Aggarwal, Rahul;
- Kurhanewicz, John;
- Vigneron, Daniel B.
Publication type:
Article
Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies.
Published in:
Magnetic Resonance in Medicine, 2018, v. 80, n. 3, p. 864, doi. 10.1002/mrm.27077
By:
- Park, Ilwoo;
- Larson, Peder E. Z.;
- Gordon, Jeremy W.;
- Carvajal, Lucas;
- Chen, Hsin‐Yu;
- Bok, Robert;
- Van Criekinge, Mark;
- Ferrone, Marcus;
- Slater, James B.;
- Xu, Duan;
- Kurhanewicz, John;
- Vigneron, Daniel B.;
- Chang, Susan;
- Nelson, Sarah J.
Publication type:
Article
In vivo hyperpolarization transfer in a clinical MRI scanner.
Published in:
Magnetic Resonance in Medicine, 2018, v. 80, n. 2, p. 480, doi. 10.1002/mrm.27154
By:
- von Morze, Cornelius;
- Reed, Galen D.;
- Larson, Peder E.;
- Mammoli, Daniele;
- Chen, Albert P.;
- Tropp, James;
- Van Criekinge, Mark;
- Ohliger, Michael A.;
- Kurhanewicz, John;
- Vigneron, Daniel B.;
- Merritt, Matthew E.
Publication type:
Article
Sensitivity enhancement for detection of hyperpolarized 13C MRI probes with 1H spin coupling introduced by enzymatic transformation in vivo.
Published in:
Magnetic Resonance in Medicine, 2018, v. 80, n. 1, p. 36, doi. 10.1002/mrm.27000
By:
- von Morze, Cornelius;
- Tropp, James;
- Chen, Albert P.;
- Marco‐Rius, Irene;
- Van Criekinge, Mark;
- Skloss, Timothy W.;
- Mammoli, Daniele;
- Kurhanewicz, John;
- Vigneron, Daniel B.;
- Ohliger, Michael A.;
- Merritt, Matthew E.
Publication type:
Article
Handheld electromagnet carrier for transfer of hyperpolarized carbon-13 samples.
Published in:
Magnetic Resonance in Medicine, 2016, v. 75, n. 2, p. 917, doi. 10.1002/mrm.25657
By:
- Shang, Hong;
- Skloss, Timothy;
- von Morze, Cornelius;
- Carvajal, Lucas;
- Van Criekinge, Mark;
- Milshteyn, Eugene;
- Larson, Peder E. Z.;
- Hurd, Ralph E.;
- Vigneron, Daniel B.
Publication type:
Article
Modeling hyperpolarized lactate signal dynamics in cells, patient‐derived tissue slice cultures and murine models.
Published in:
NMR in Biomedicine, 2021, v. 34, n. 3, p. 1, doi. 10.1002/nbm.4467
By:
- Ahamed, Fayyaz;
- Van Criekinge, Mark;
- Wang, Zhen J.;
- Kurhanewicz, John;
- Larson, Peder;
- Sriram, Renuka
Publication type:
Article
Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.
Published in:
NMR in Biomedicine, 2015, v. 28, n. 9, p. 1141, doi. 10.1002/nbm.3354
By:
- Sriram, Renuka;
- Van Criekinge, Mark;
- Hansen, Ailin;
- Wang, Zhen J.;
- Vigneron, Daniel B.;
- Wilson, David M.;
- Keshari, Kayvan R.;
- Kurhanewicz, John
Publication type:
Article
Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures.
Published in:
Cancers, 2020, v. 12, n. 3, p. 537, doi. 10.3390/cancers12030537
By:
- Sriram, Renuka;
- Van Criekinge, Mark;
- DeLos Santos, Justin;
- Ahamed, Fayyaz;
- Qin, Hecong;
- Nolley, Rosalie;
- DeLos Santos, Romelyn;
- Tabatabai, Z. Laura;
- Bok, Robert A.;
- Keshari, Kayvan R.;
- Vigneron, Daniel B.;
- Peehl, Donna M.;
- Kurhanewicz, John
Publication type:
Article
Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor.
Published in:
Prostate, 2015, v. 75, n. 14, p. 1601, doi. 10.1002/pros.23036
By:
- Keshari, Kayvan R.;
- Wilson, David M.;
- Van Criekinge, Mark;
- Sriram, Renuka;
- Koelsch, Bertram L.;
- Wang, Zhen J.;
- VanBrocklin, Henry F.;
- Peehl, Donna M.;
- O'Brien, Tom;
- Sampath, Deepak;
- Carano, Richard A. D.;
- Kurhanewicz, John
Publication type:
Article
Metabolic Reprogramming and Validation of Hyperpolarized 13 C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor.
Published in:
Prostate, 2013, v. 73, n. 11, p. 1171, doi. 10.1002/pros.22665
By:
- Keshari, Kayvan R.;
- Sriram, Renuka;
- Van Criekinge, Mark;
- Wilson, David M.;
- Wang, Zhen J.;
- Vigneron, Daniel B.;
- Peehl, Donna M.;
- Kurhanewicz, John
Publication type:
Article
Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate.
Published in:
Science Translational Medicine, 2013, v. 5, n. 198, p. 1, doi. 10.1126/scitranslmed.3006070
By:
- Nelson, Sarah J.;
- Kurhanewicz, John;
- Vigneron, Daniel B.;
- Larson, Peder E. Z.;
- Harzstark, Andrea L.;
- Ferrone, Marcus;
- van Criekinge, Mark;
- Chang, Jose W.;
- Bok, Robert;
- Park, Ilwoo;
- Reed, Galen;
- Carvajal, Lucas;
- Small, Eric J.;
- Munster, Pamela;
- Weinberg, Vivian K.;
- Ardenkjaer-Larsen, Jan Henrik;
- Chen, Albert P.;
- Hurd, Ralph E.;
- Odegardstuen, Liv-Ingrid;
- Robb, Fraser J.
Publication type:
Article
Hyperpolarized 13C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism.
Published in:
Magnetic Resonance in Medicine, 2010, v. 63, n. 2, p. 322, doi. 10.1002/mrm.22225
By:
- Keshari, Kayvan R.;
- Kurhanewicz, John;
- Jeffries, Rex E.;
- Wilson, David M.;
- Dewar, Brian J.;
- Van Criekinge, Mark;
- Zierhut, Matthew;
- Vigneron, Daniel B.;
- Macdonald, Jeffrey M.
Publication type:
Article
Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance.
Published in:
2015
By:
- Keshari, Kayvan R;
- Wilson, David M;
- Sai, Victor;
- Bok, Robert;
- Jen, Kuang-Yu;
- Larson, Peder;
- Van Criekinge, Mark;
- Kurhanewicz, John;
- Wang, Zhen J
Publication type:
journal article
Noninvasive In Vivo Imaging of Diabetes-Induced Renal Oxidative Stress and Response to Therapy Using Hyperpolarized 13C Dehydroascorbate Magnetic Resonance.
Published in:
Diabetes, 2015, v. 64, n. 2, p. 344, doi. 10.2337/db13-1829
By:
- Keshari, Kayvan R.;
- Wilson, David M.;
- Sai, Victor;
- Bok, Robert;
- Kuang-Yu Jen;
- Larson, Peder;
- Van Criekinge, Mark;
- Kurhanewicz, John;
- Wang, Zhen J.
Publication type:
Article

Found: 18

Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models.

Clinical translation of hyperpolarized <sup>13</sup>C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging.

Specialized computational methods for denoising, B<sub>1</sub> correction, and kinetic modeling in hyperpolarized <sup>13</sup>C MR EPSI studies of liver tumors.

Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.

Technique development of 3D dynamic CS‐EPSI for hyperpolarized <sup>13</sup>C pyruvate MR molecular imaging of human prostate cancer.

Development of methods and feasibility of using hyperpolarized carbon‐13 imaging data for evaluating brain metabolism in patient studies.

In vivo hyperpolarization transfer in a clinical MRI scanner.

Sensitivity enhancement for detection of hyperpolarized <sup>13</sup>C MRI probes with <sup>1</sup>H spin coupling introduced by enzymatic transformation in vivo.

Handheld electromagnet carrier for transfer of hyperpolarized carbon-13 samples.

Modeling hyperpolarized lactate signal dynamics in cells, patient‐derived tissue slice cultures and murine models.

Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.

Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures.

Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor.

Metabolic Reprogramming and Validation of Hyperpolarized <sup>13</sup> C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor.

Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-<sup>13</sup>C]Pyruvate.

Hyperpolarized <sup>13</sup>C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism.

Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance.

Noninvasive In Vivo Imaging of Diabetes-Induced Renal Oxidative Stress and Response to Therapy Using Hyperpolarized <sup>13</sup>C Dehydroascorbate Magnetic Resonance.