Works by Vallon, Volker

Results: 75

An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption.

Published in:

2006

By:

Thomson, Scott C.;
Deng, Aihua;
Wead, Lucinda;
Richter, Kerstin;
Blantz, Roland C.;
Vallon, and Volker;
Vallon, Volker

Publication type:

journal article

Effects of sotagliflozin on kidney and cardiac outcome in a hypertensive model of subtotal nephrectomy in male mice.

Published in:

Physiological Reports, 2025, v. 13, n. 7, p. 1, doi. 10.14814/phy2.70217

By:

Goodluck, Helen;
Zemljic‐Harpf, Alice;
Galdino, Ony Araujo;
Kanoo, Sadhana;
Lopez, Natalia;
Kim, Young Chul;
Vallon, Volker

Publication type:

Article

The Potential Role of SGLT2 Inhibitors in the Treatment of Type 1 Diabetes Mellitus.

Published in:

Drugs, 2018, v. 78, n. 7, p. 717, doi. 10.1007/s40265-018-0901-y

By:

Fattah, Hadi;
Vallon, Volker

Publication type:

Article

Adenosine and kidney function: Potential implications in patients with heart failure

Published in:

European Journal of Heart Failure, 2008, v. 10, n. 2, p. 176, doi. 10.1016/j.ejheart.2008.01.010

By:

Vallon, Volker;
Miracle, Cindy;
Thomson, Scott

Publication type:

Article

Deletion of the Sodium Glucose Cotransporter 1 (Sglt‐1) impairs mouse sperm movement.

Published in:

Molecular Reproduction & Development, 2024, v. 91, n. 1, p. 1, doi. 10.1002/mrd.23723

By:

Numata, September;
Oishee, Mumtarin Jannat;
McDermott, Jeffrey;
Koepsell, Hermann;
Vallon, Volker;
Blanco, Gustavo

Publication type:

Article

A special issue on glucose transporters in health and disease.

Published in:

2020

By:

Koepsell, Hermann;
Vallon, Volker

Publication type:

Editorial

Glucose transporters in the kidney in health and disease.

Published in:

Pflügers Archiv: European Journal of Physiology, 2020, v. 472, n. 9, p. 1345, doi. 10.1007/s00424-020-02361-w

By:

Vallon, Volker

Publication type:

Article

Micropuncturing the nephron.

Published in:

Pflügers Archiv: European Journal of Physiology, 2009, v. 458, n. 1, p. 189, doi. 10.1007/s00424-008-0581-7

By:

Vallon, Volker

Publication type:

Article

Renal Ca2+ handling in sgk1 knockout mice.

Published in:

Pflügers Archiv: European Journal of Physiology, 2006, v. 452, n. 4, p. 444, doi. 10.1007/s00424-005-0021-x

By:

Sandulache, Diana;
Grahammer, Florian;
Artunc, Ferruh;
Henke, Guido;
Hussain, Azeemudeen;
Nasir, Omaima;
Mack, Andreas;
Friedrich, Björn;
Vallon, Volker;
Wulff, Peer;
Kuhl, Dietmar;
Palmada, Monica;
Lang, Florian

Publication type:

Article

Impaired ability to increase water excretion in mice lacking the taurine transporter gene TAUT.

Published in:

Pflügers Archiv: European Journal of Physiology, 2006, v. 451, n. 5, p. 668, doi. 10.1007/s00424-005-1499-y

By:

Huang, Dan;
Boini, Krishna;
Lang, Philipp;
Grahammer, Florian;
Duszenko, Michael;
Heller-Stilb, Birgit;
Warskulat, Ulrich;
Häussinger, Dieter;
Lang, Florian;
Vallon, Volker

Publication type:

Article

Expression and insights on function of potassium channel TWIK-1 in mouse kidney.

Published in:

Pflügers Archiv: European Journal of Physiology, 2005, v. 451, n. 3, p. 479, doi. 10.1007/s00424-005-1480-9

By:

Xin Nie;
Arrighi, Isabelle;
Kaissling, Brigitte;
Pfaff, Imke;
Mann, Jeffrey;
Barhanin, Jacques;
Vallon, Volker

Publication type:

Article

Regulation of KCNE1-dependent K+ current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.

Published in:

Pflügers Archiv: European Journal of Physiology, 2003, v. 445, n. 5, p. 601, doi. 10.1007/s00424-002-0982-y

By:

Embark, Hamdy M.;
Böhmer, Christoph;
Vallon, Volker;
Luft, Friedrich;
Lang, Florian

Publication type:

Article

Tubuloglomerular feedback in the kidney: insights from gene-targeted mice.

Published in:

Pflügers Archiv: European Journal of Physiology, 2003, v. 445, n. 4, p. 470, doi. 10.1007/s00424-002-0952-4

By:

Vallon, Volker

Publication type:

Article

Development of SGLT1 and SGLT2 inhibitors.

Published in:

Diabetologia, 2018, v. 61, n. 10, p. 2079, doi. 10.1007/s00125-018-4654-7

By:

Rieg, Timo;
Vallon, Volker

Publication type:

Article

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition.

Published in:

Diabetologia, 2017, v. 60, n. 2, p. 215, doi. 10.1007/s00125-016-4157-3

By:

Vallon, Volker;
Thomson, Scott

Publication type:

Article

Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00274

By:

Yasong Lu;
Griffen, Steven C.;
Boulton, David W.;
Leil, Tarek A.;
Vallon, Volker;
Sabino-Silva, Robinson

Publication type:

Article

Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences.

Published in:

Diabetes & Vascular Disease Research, 2015, v. 12, n. 2, p. 78, doi. 10.1177/1479164114561992

By:

Gallo, Linda A;
Wright, Ernest M;
Vallon, Volker

Publication type:

Article

Sustained Exposure to the SGLT2 Inhibitor Ertugliflozin, But Not NHE‐1 Inhibition By Cariporide, Attenuates Adrenergic Stimulation of Cytosolic CA2+ Levels in Spontaneously Contracting Cardiac Myocytes.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2252

By:

Alam, Sifat M.;
Gierden, Kyle J.;
Zhao, Tengteng;
Lu, Sun S.;
Dixit, Mihir;
Babicheva, Aleksandra;
Yuan, Jason;
Vallon, Volker;
Zemljic‐Harpf, Alice E.

Publication type:

Article

Systemic proteomic and metabolomic signature of the SGLT2 inhibitor dapagliflozin.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4450

By:

Billing, Anja;
Kim, Young‐Chul;
Vallon, Volker;
Rinschen, Markus

Publication type:

Article

Deletion of eNOS enhances kidney injury in BTBR ob/ob mice.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04952

By:

Kanoo, Sadhana;
Goodluck, Helen;
Kim, Young Chul;
Garrido, Aleix Navarro;
Crespo‐Masip, Maria;
Zhang, Haiyan;
Villalobos, Romer Gonzalez;
Ma, Li‐Jun;
Vallon, Volker

Publication type:

Article

Deletion of PTEN and VDR impair glucose and lipid metabolism.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02397

By:

Crespo‐Masip, Maria;
Pérez, Aurora;
Guzmán, Carla;
Garcia, Alicia;
Jover, Ramiro;
Vallon, Volker;
Valdivielso, Jose Manuel

Publication type:

Article

Basal renal phenotype and response to induction of aristolochic acid nephropathy in mice lacking the neutral amino acid transporter B0AT1 (SLC6A19).

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04004

By:

Navarro Garrido, Aleix;
Kim, Young Chul;
Goodluck, Helen;
Kanoo, Sadhana;
Crespo‐Masip, Maria;
Bröer, Stefan;
Vallon, Volker

Publication type:

Article

Dietary NaCl modulates the urinary organic metabolite profile: influence of the organic anion transporter OAT3 (892.34).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.892.34

By:

Vallon, Volker;
Fu, Yiling;
Kuczkowski, Alexander;
Anzai, Naohiko;
Nigam, Sanjay;
Eraly, Satish;
Gerasimova, Maria;
Ramachandra Rao, Satish

Publication type:

Article

What makes SGLT2 inhibition so effective in lowering blood glucose in diabetes? (689.5).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.689.5

By:

Gerasimova, Maria;
Rose, Michael;
Koepsell, Hermann;
Masuda, Takahiro;
Mayoux, Eric;
Thomson, Scott;
Rieg, Timo;
Vallon, Volker

Publication type:

Article

Dipeptidyl peptidase‐4 inhibitor lowers PPARγ agonist‐induced body weight gain by affecting food intake, fat mass and beige/brown fat but not fluid retention (1160.9).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1160.9

By:

Fu, Yiling;
Masuda, Takahiro;
Eguchi, Akiko;
Czogalla, Jan;
Rose, Michael;
Kuczkowski, Alexander;
Gerasimova, Maria;
Feldstein, Ariel;
Scadeng, Miriam;
Vallon, Volker

Publication type:

Article

Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone.

Published in:

FASEB Journal, 2010, v. 24, n. 6, p. 2056, doi. 10.1096/fj.09-151506

By:

Pochynyuk, Oleh;
Rieg, Timo;
Bugaj, Vladislav;
Schroth, Jana;
Fridman, Alla;
Boss, Gerry R.;
Insel, Paul A.;
Stockand, James D.;
Vallon, Volker

Publication type:

Article

Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption.

Published in:

FASEB Journal, 2007, v. 21, n. 13, p. 3717, doi. 10.1096/fj.07-8807com

By:

Rieg, Timo;
Bundey, Richard A.;
Yu Chen;
Deschenes, George;
Junger, Wolfgang;
Insel, Paul A.;
Vallon, Volker

Publication type:

Article

Adenosine A1 receptor blockade and the balance of bicarbonate/chloride transport in the proximal tubule.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A437, doi. 10.1096/fasebj.21.5.a437-c

By:

Rieg, Timo Marcel;
Miracle, Cynthia;
Blantz, Roland;
Vallon, Volker;
Thomson, Scott

Publication type:

Article

The Pathophysiological Basis of Diabetic Kidney Protection by Inhibition of SGLT2 and SGLT1.

Published in:

Kidney & Dialysis, 2022, v. 2, n. 2, p. 349, doi. 10.3390/kidneydial2020032

By:

Oe, Yuji;
Vallon, Volker

Publication type:

Article

Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.

Published in:

Expert Opinion on Therapeutic Targets, 2016, v. 20, n. 9, p. 1109, doi. 10.1517/14728222.2016.1168808

By:

Song, Panai;
Onishi, Akira;
Koepsell, Hermann;
Vallon, Volker

Publication type:

Article

Did you know how SGLT2 inhibitors protect the kidney?

Published in:

Acta Physiologica, 2023, v. 238, n. 4, p. 1, doi. 10.1111/apha.14011

By:

Layton, Anita T.;
Vallon, Volker

Publication type:

Article

Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha.

Published in:

2007

By:

Zhang, Wenzheng;
Xia, Xuefeng;
Reisenauer, Mary Rose;
Rieg, Timo;
Lang, Florian;
Kuhl, Dietmar;
Vallon, Volker;
Kone, Bruce C

Publication type:

journal article

Aldosterone-induced Sgk1 relieves Dot1a-Af9--mediated transcriptional repression of epithelial Na+ channel α.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 3, p. 773, doi. 10.1172/JCI29850

By:

Wenzheng Zhang;
Xuefeng Xia;
Reisenauer, Mary Rose;
Rieg, Timo;
Lang, Florian;
Kuhl, Dietmar;
Vallon, Volker;
Kone, Bruce C.

Publication type:

Article

Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 6, p. 1651, doi. 10.1172/JCI24134

By:

Nijenhuis, Tom;
Vallon, Volker;
van der Kemp, Annemiete W. C. M.;
Loffing, Johannes;
Hoenderop, Joost G. J.;
Bindels, René J. M.

Publication type:

Article

DOCA-induced Phosphorylation of Glycogen Synthase Kinase 3ß.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2006, v. 17, n. 3/4, p. 137, doi. 10.1159/000092075

By:

Wyatt, Amanda;
Hussain, Azeemudeen;
Amann, Kerstin;
Klingel, Karin;
Kandolf, Reinhard;
Artunc, Ferruh;
Grahammer, Florian;
Dan Yang Huang;
Vallon, Volker;
Kuhl, Dietmar;
Lang, Florian

Publication type:

Article

Blunted Apoptosis of Erythrocytes from Taurine Transporter Deficient Mice.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2003, v. 13, n. 6, p. 337, doi. 10.1159/000075121

By:

Lang, Philipp A.;
Warskulat, Ulrich;
Heller-Stilb, Birgit;
Huang, Dan Y.;
Grenz, Almut;
Myssina, Svetlana;
Duszenko, Michael;
Lang, Florian;
Häussinger, Dieter;
Vallon, Volker;
Wieder, Thomas

Publication type:

Article

Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice.

Published in:

Scientific Reports, 2016, p. 26428, doi. 10.1038/srep26428

By:

Gallo, Linda A.;
Ward, Micheal S.;
Fotheringham, Amelia K.;
Zhuang, Aowen;
Borg, Danielle J.;
Flemming, Nicole B.;
Harvie, Ben M.;
Kinneally, Toni L.;
Yeh, Shang-Ming;
McCarthy, Domenica A.;
Koepsell, Hermann;
Vallon, Volker;
Pollock, Carol;
Panchapakesan, Usha;
Forbes, Josephine M.

Publication type:

Article

Sodium reabsorption in thick ascending limb of Henle's loop: effect of potassium channel blockade in vivo.

Published in:

British Journal of Pharmacology, 2000, v. 130, n. 6, p. 1255, doi. 10.1038/sj.bjp.0703429

By:

Huang, Dan Y;
Osswald, Hartmut;
Vallon, Volker

Publication type:

Article

Osmotic diuresis by SGLT2 inhibition stimulates vasopressin‐induced water reabsorption to maintain body fluid volume.

Published in:

Physiological Reports, 2020, v. 8, n. 2, p. N.PAG, doi. 10.14814/phy2.14360

By:

Masuda, Takahiro;
Muto, Shigeaki;
Fukuda, Keiko;
Watanabe, Minami;
Ohara, Ken;
Koepsell, Hermann;
Vallon, Volker;
Nagata, Daisuke

Publication type:

Article

The salt paradox and its possible implications in managing hypertensive diabetic patients.

Published in:

Current Hypertension Reports, 2005, v. 7, n. 2, p. 141, doi. 10.1007/s11906-005-0089-x

By:

Vallon, Volker;
Blantz, Roland;
Thomson, Scott

Publication type:

Article

Renal Clearance of Fibroblast Growth Factor‐23 (FGF23) and its Fragments in Humans.

Published in:

Journal of Bone & Mineral Research, 2022, v. 37, n. 6, p. 1170, doi. 10.1002/jbmr.4553

By:

Sharma, Shilpa;
Katz, Ronit;
Ginsberg, Charles;
Bullen, Alexander;
Vallon, Volker;
Thomson, Scott;
Moe, Orson W.;
Hoofnagle, Andrew N.;
de Leeuw, Peter W.;
Kroon, Abraham A.;
Houben, Alfons J.H.M.;
Ix, Joachim H.

Publication type:

Article

SGK, renal function and hypertension.

Published in:

Journal of Nephrology (JNonline), 2010, v. 23, p. S124

By:

Lang, Florian;
Dan Yang Huang;
Vallon, Volker

Publication type:

Article

Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1.

Published in:

Journal of Molecular Medicine, 2006, v. 84, n. 9, p. 737, doi. 10.1007/s00109-006-0082-0

By:

Artunc, Ferruh;
Amann, Kerstin;
Nasir, Omaima;
Friedrich, Björn;
Sandulache, Diana;
Jahovic, Nermina;
Risler, Teut;
Vallon, Volker;
Wulff, Peer;
Kuhl, Dietmar;
Lang, Florian

Publication type:

Article

SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment.

Published in:

Journal of Molecular Medicine, 2006, v. 84, n. 5, p. 396, doi. 10.1007/s00109-005-0027-z

By:

Vallon, Volker;
Wyatt, Amanda W.;
Klingel, Karin;
Dan Yang Huang;
Hussain, Azeemudeen;
Berchtold, Susanne;
Friedrich, Björn;
Grahammer, Florian;
BelAiba, Rachida S.;
Görlach, Agnes;
Wulff, Peer;
Daut, Jürgen;
Dalton, Nancy D.;
Ross Jr., John;
Flögel, Ulrich;
Schrader, Jürgen;
Osswald, Hartmut;
Kandolf, Reinhard;
Kuhl, Dietmar;
Lang, Florian

Publication type:

Article

Deletion, but Not Heterozygosity, of eNOS Raises Blood Pressure and Aggravates Nephropathy in BTBR ob/ob Mice.

Published in:

Nephron, 2024, v. 148, n. 9, p. 631, doi. 10.1159/000536522

By:

Kanoo, Sadhana;
Goodluck, Helen;
Kim, Young Chul;
Garrido, Aleix Navarro;
Crespo-Masip, Maria;
Lopez, Natalia;
Zhang, Haiyan;
Gonzalez-Villalobos, Romer A.;
Ma, Li-Jun;
Vallon, Volker

Publication type:

Article

CRRT 2023 Meeting: Targeting Amino Acid Transport to Improve Acute Kidney Injury Outcome.

Published in:

Nephron, 2023, v. 147, n. 12, p. 774, doi. 10.1159/000531918

By:

Oe, Yuji;
Vallon, Volker

Publication type:

Article

Responses in Blood Pressure and Kidney Function to Soluble Guanylyl Cyclase Stimulation or Activation in Normal and Diabetic Rats.

Published in:

Nephron, 2023, v. 147, n. 5, p. 281, doi. 10.1159/000526934

By:

Patel, Rohit;
Fu, Yiling;
Khang, Ser;
Benardeau, Agnes M.;
Thomson, Scott C.;
Vallon, Volker

Publication type:

Article

Western Diet Promotes Renal Injury, Inflammation, and Fibrosis in a Murine Model of Alström Syndrome.

Published in:

Nephron, 2020, v. 144, n. 8, p. 400, doi. 10.1159/000508636

By:

Kim, Young Chul;
Ganguly, Souradipta;
Nespoux, Josselin;
Freeman, Brent;
Zhang, Haiyan;
Brenner, David;
Dhar, Debanjan;
Vallon, Volker

Publication type:

Article

State-of-the-Art-Review: Mechanisms of Action of SGLT2 Inhibitors and Clinical Implications.

Published in:

American Journal of Hypertension, 2024, v. 37, n. 11, p. 841, doi. 10.1093/ajh/hpae092

By:

Vallon, Volker

Publication type:

Article

Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport.

Published in:

Clinical & Experimental Nephrology, 2012, v. 16, n. 1, p. 73, doi. 10.1007/s10157-011-0488-z

By:

Lang, Florian;
Vallon, Volker

Publication type:

Article