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Tim-1 regulates Th2 responses in an airway hypersensitivity model.
Published in:
European Journal of Immunology, 2012, v. 42, n. 3, p. 651, doi. 10.1002/eji.201141581
By:
- Curtiss, Miranda L.;
- Gorman, Jacob V.;
- Businga, Thomas R.;
- Traver, Geri;
- Singh, Melody;
- Meyerholz, David K.;
- Kline, Joel N.;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Colgan, John D.;
- Rothman, Paul B.;
- Cassel, Suzanne L.
Publication type:
Article
ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.
Published in:
Journal of Pathology, 2016, v. 240, n. 4, p. 461, doi. 10.1002/path.4805
By:
- Gomez Perdiguero, Elisa;
- Liabotis‐Fontugne, Athanasia;
- Durand, Mélanie;
- Faye, Clément;
- Ricard‐Blum, Sylvie;
- Simonutti, Manuel;
- Augustin, Sébastien;
- Robb, Bryan M;
- Paques, Michel;
- Valenzuela, David M;
- Murphy, Andrew J;
- Yancopoulos, George D;
- Thurston, Gavin;
- Galaup, Ariane;
- Monnot, Catherine;
- Germain, Stéphane
Publication type:
Article
Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.
Published in:
BMC Biology, 2020, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12915-020-00877-2
By:
- Espinoza, Sofía;
- Arredondo, Sebastián B.;
- Barake, Francisca;
- Carvajal, Francisco;
- Guerrero, Fernanda G.;
- Segovia-Miranda, Fabian;
- Valenzuela, David M.;
- Wyneken, Ursula;
- Rojas-Fernández, Alejandro;
- Cerpa, Waldo;
- Massardo, Loreto;
- Varela-Nallar, Lorena;
- González, Alfonso
Publication type:
Article
Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.
Published in:
2011
By:
- Lutz, Cathleen M.;
- Kariya, Shingo;
- Patruni, Sunita;
- Osborne, Melissa A.;
- Liu, Don;
- Henderson, Christopher E.;
- Li, Darrick K.;
- Pellizzoni, Livio;
- Rojas, José;
- Valenzuela, David M.;
- Murphy, Andrew J.;
- Winberg, Margaret L.;
- Monani, Umrao R.;
- Rojas, José
Publication type:
journal article
TLR8 deficiency leads to autoimmunity in mice.
Published in:
2010
By:
- Demaria, Olivier;
- Pagni, Philippe P.;
- Traub, Stephanie;
- de Gassart, Aude;
- Branzk, Nora;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Flavell, Richard A.;
- Alexopoulou, Lena
Publication type:
journal article
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.
Published in:
2008
By:
- Shmelkov, Sergey V.;
- Butler, Jason M.;
- Hooper, Andrea T.;
- Hormigo, Adilia;
- Kushner, Jared;
- Milde, Till;
- St. Clair, Ryan;
- Baljevic, Muhamed;
- White, Ian;
- Jin, David K.;
- Chadburn, Amy;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Gale, Nicholas W.;
- Thurston, Gavin;
- Yancopoulos, George D.;
- D'Angelica, Michael;
- Kemeny, Nancy;
- Lyden, David;
- Rafii, Shahin
Publication type:
journal article
F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.
Published in:
Nature Biotechnology, 2007, v. 25, n. 1, p. 91, doi. 10.1038/nbt1263
By:
- Poueymirou, William T.;
- Auerbach, Wojtek;
- Frendewey, David;
- Hickey, Joseph F.;
- Escaravage, Jennifer M.;
- Esau, Lakeisha;
- Doré, Anthony T.;
- Stevens, Sean;
- Adams, Niels C.;
- Dominguez, Melissa G.;
- Gale, Nicholas W.;
- Yancopoulos, George D.;
- DeChiara, Thomas M.;
- Valenzuela, David M.
Publication type:
Article
Corrigenda: High-throughput engineering of the mouse genome coupled with high-resolution expression analysis.
Published in:
2003
By:
- Valenzuela, David M;
- Murphy, Andrew J;
- Frendewey, David;
- Gale, Nicholas W;
- Economides, Aris N;
- Auerbach, Wojtek;
- Poueymirou, William T;
- Adams, Niels C;
- Rojas, Jose;
- Yasenchak, Jason;
- Chernomorski, Rostislav;
- Boucher, Marylene;
- Elsasser, Andrea L;
- Esau, Lakeisha;
- Zheng, Jenny;
- Griffiths, Jennifer;
- Wang, Xiaorong;
- Su, Hong;
- Xue, Yingzi
Publication type:
Correction Notice
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis.
Published in:
Nature Biotechnology, 2003, v. 21, n. 6, p. 652, doi. 10.1038/nbt822
By:
- Valenzuela, David M;
- Murphy, Andrew J;
- Frendewey, David;
- Gale, Nicholas W;
- Economides, Aris N;
- Auerbach, Wojtek;
- Poueymirou, William T;
- Adams, Niels C;
- Rojas, Jose;
- Yasenchak, Jason;
- Chernomorsky, Rostislav;
- Boucher, Marylene;
- Elsasser, Andrea L;
- Esau, Lakeisha;
- Zheng, Jenny;
- Griffiths, Jennifer A;
- Wang, Xiaorong;
- Su, Hong;
- Xue, Yingzi
Publication type:
Article
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive–like behaviors in mice.
Published in:
Nature Medicine, 2010, v. 16, n. 5, p. 598, doi. 10.1038/nm.2125
By:
- Shmelkov, Sergey V.;
- Hormigo, Adília;
- Deqiang Jing;
- Proenca, Catia C.;
- Bath, Kevin G.;
- Milde, Till;
- Shmelkov, Evgeny;
- Kushner, Jared S.;
- Baljevic, Muhamed;
- Dincheva, Iva;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Gale, Nicholas W.;
- Yancopoulos, George D.;
- Ninan, Ipe;
- Lee, Francis S;
- Rafii, Shahin
Publication type:
Article
Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development.
Published in:
Nature Genetics, 2000, v. 24, n. 3, p. 271, doi. 10.1038/73488
By:
- DeChiara, Thomas M.;
- Kimble, Robert B.;
- Poueymirou, William T.;
- Rojas, Jose;
- Masiakowski, Piotr;
- Valenzuela, David M.;
- Yancopoulos, George D.
Publication type:
Article
Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B.
Published in:
Nature Genetics, 2000, v. 24, n. 3, p. 275, doi. 10.1038/73495
By:
- Oldridge, Michael;
- M Fortuna, Ana;
- Maringa, Monika;
- Propping, Peter;
- Mansour, Sahar;
- Pollitt, Christine;
- DeChiara, Thomas M.;
- Kimble, Robert B.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Wilkie, Andrew O.M.
Publication type:
Article
Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K<sup>+</sup> Channel.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0139284
By:
- Villanueva, Sandra;
- Burgos, Johanna;
- López-Cayuqueo, Karen I.;
- Lai, Ka-Man Venus;
- Valenzuela, David M.;
- Cid, L. Pablo;
- Sepúlveda, Francisco V.
Publication type:
Article
Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125522
By:
- Lai, Ka-Man Venus;
- Gong, Guochun;
- Atanasio, Amanda;
- Rojas, José;
- Quispe, Joseph;
- Posca, Julita;
- White, Derek;
- Huang, Mei;
- Fedorova, Daria;
- Grant, Craig;
- Miloscio, Lawrence;
- Droguett, Gustavo;
- Poueymirou, William T.;
- Auerbach, Wojtek;
- Yancopoulos, George D.;
- Frendewey, David;
- Rinn, John;
- Valenzuela, David M.
Publication type:
Article
Peripheral Myelin Protein 22 Is in Complex with α6β4 Integrin, and Its Absence Alters the Schwann Cell Basal Lamina.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 4, p. 1179, doi. 10.1523/JNEUROSCI.2618-05.2006
By:
- Amici, Stephanie A.;
- Dunn Jr., William A.;
- Murphy, Andrew J.;
- Adams, Niels C.;
- Gale, Nicholas W.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Notterpek, Lucia
Publication type:
Article
Generation of functional multipotent adult stem cells from GPR125<sup>+</sup> germline progenitors.
Published in:
Nature, 2007, v. 449, n. 7160, p. 346, doi. 10.1038/nature06129
By:
- Seandel, Marco;
- James, Daylon;
- Shmelkov, Sergey V.;
- Falciatori, Ilaria;
- Kim, Jiyeon;
- Chavala, Sai;
- Scherr, Douglas S.;
- Zhang, Fan;
- Torres, Richard;
- Gale, Nicholas W.;
- Yancopoulos, George D.;
- Murphy, Andrew;
- Valenzuela, David M.;
- Hobbs, Robin M.;
- Pandolfi, Pier Paolo;
- Rafii, Shahin
Publication type:
Article
Mice completely lacking immunoproteasomes show major changes in antigen presentation.
Published in:
Nature Immunology, 2012, v. 13, n. 2, p. 129, doi. 10.1038/ni.2203
By:
- Kincaid, Eleanor Z;
- Che, Jenny W;
- York, Ian;
- Escobar, Hernando;
- Reyes-Vargas, Eduardo;
- Delgado, Julio C;
- Welsh, Raymond M;
- Karow, Margaret L;
- Murphy, Andrew J;
- Valenzuela, David M;
- Yancopoulos, George D;
- Rock, Kenneth L
Publication type:
Article
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain.
Published in:
Nature Immunology, 2008, v. 9, n. 1, p. 25, doi. 10.1038/ni1544
By:
- Ramalingam, Thirumalai R;
- Pesce, John T;
- Sheikh, Faruk;
- Cheever, Allen W;
- Mentink-Kane, Margaret M;
- Wilson, Mark S;
- Stevens, Sean;
- Valenzuela, David M;
- Murphy, Andrew J;
- Yancopoulos, George D;
- Urban, Joseph F;
- Donnelly, Raymond P;
- Wynn, Thomas A
Publication type:
Article
'AMERICA BELONGS TO AMERICANS': AMERICAN PUBLIC OPINION AND THE RIVALRY U.S.- SPAIN FOR THE DOMINICAN REPUBLIC, 1854-1865.
Published in:
Hemispheric & Polar Studies Journal / Revista Estudios Hemisféricos y Polares, 2018, v. 9, n. 1, p. 11
By:
- Valenzuela, M. A. David Home
Publication type:
Article
IL-22 Promotes Fibroblast-Mediated Wound Repair in the Skin.
Published in:
Journal of Investigative Dermatology, 2013, v. 133, n. 5, p. 1321, doi. 10.1038/jid.2012.463
By:
- McGee, Heather M;
- Schmidt, Barbara A;
- Booth, Carmen J;
- Yancopoulos, George D;
- Valenzuela, David M;
- Murphy, Andrew J;
- Stevens, Sean;
- Flavell, Richard A;
- Horsley, Valerie
Publication type:
Article
During muscle atrophy, thick, but not thin, filament components are degraded by MuRF 1-dependent ubiquitylation.
Published in:
Journal of Cell Biology, 2009, v. 185, n. 6, p. 1083, doi. 10.1083/jcb.200901052
By:
- Cohen, Shenhav;
- Brault, Jeffrey J.;
- Gygi, Steven P.;
- Glass, David J.;
- Valenzuela, David M.;
- Gartner, Carlos;
- Latres, Esther;
- Goldberg, Alfred L.
Publication type:
Article
Radiologic evaluation of coronary artery disease in adults with congenital heart disease.
Published in:
2016
By:
- Valenzuela, David;
- Ordovas, Karen;
- Valenzuela, David M;
- Ordovas, Karen G
Publication type:
journal article
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Published in:
Nature, 2015, v. 517, n. 7534, p. 381, doi. 10.1038/nature14053
By:
- Deng, Kai;
- Pertea, Mihaela;
- Rongvaux, Anthony;
- Wang, Leyao;
- Durand, Christine M.;
- Ghiaur, Gabriel;
- Lai, Jun;
- McHugh, Holly L.;
- Hao, Haiping;
- Zhang, Hao;
- Margolick, Joseph B.;
- Gurer, Cagan;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Deeks, Steven G.;
- Strowig, Till;
- Kumar, Priti;
- Siliciano, Janet D.;
- Salzberg, Steven L.
Publication type:
Article
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
Published in:
Nature, 2012, v. 491, n. 7423, p. 259, doi. 10.1038/nature11535
By:
- Huber, Samuel;
- Gagliani, Nicola;
- Zenewicz, Lauren A.;
- Huber, Francis J.;
- Bosurgi, Lidia;
- Hu, Bo;
- Hedl, Matija;
- Zhang, Wei;
- O'Connor, William;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Booth, Carmen J.;
- Cho, Judy H.;
- Ouyang, Wenjun;
- Abraham, Clara;
- Flavell, Richard A.
Publication type:
Article
Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke.
Published in:
European Heart Journal, 2013, v. 34, n. 47, p. 3657, doi. 10.1093/eurheartj/eht153
By:
- Bouleti, Claire;
- Mathivet, Thomas;
- Coqueran, Berard;
- Serfaty, Jean-Michel;
- Lesage, Mathieu;
- Berland, Elodie;
- Ardidie-Robouant, Corinne;
- Kauffenstein, Gilles;
- Henrion, Daniel;
- Lapergue, Bertrand;
- Mazighi, Mikael;
- Duyckaerts, Charles;
- Thurston, Gavin;
- Valenzuela, David M.;
- Murphy, Andrew J.;
- Yancopoulos, George D.;
- Monnot, Catherine;
- Margaill, Isabelle;
- Germain, Stephane
Publication type:
Article
Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein α Subunit Membrane Association.
Published in:
Science Signaling, 2011, v. 4, n. 200, p. 1, doi. 10.1126/scisignal.2002223
By:
- Gabay, Meital;
- Pinter, Mary E.;
- Wright, Forrest A.;
- Pui Yee Chan;
- Murphy, Andrew J.;
- Valenzuela, David M.;
- Yancopoulos, George D.;
- Tall, Gregory G.
Publication type:
Article
Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177472
By:
- Pardo, Evelyn;
- Cárcamo, Claudia;
- Uribe-San Martín, Reinaldo;
- Ciampi, Ethel;
- Segovia-Miranda, Fabián;
- Curkovic-Peña, Cristobal;
- Montecino, Fabián;
- Holmes, Christopher;
- Tichauer, Juan Enrique;
- Acuña, Eric;
- Osorio-Barrios, Francisco;
- Castro, Marjorie;
- Cortes, Priscilla;
- Oyanadel, Claudia;
- Valenzuela, David M.;
- Pacheco, Rodrigo;
- Naves, Rodrigo;
- Soza, Andrea;
- González, Alfonso
Publication type:
Article
Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177192
By:
- Takahashi, Keiko;
- Kim, Rachel;
- Lauhan, Colette;
- Park, Yuna;
- Nguyen, Nghiep G.;
- Vestweber, Dietmar;
- Dominguez, Melissa G.;
- Valenzuela, David M.;
- Murphy, Andrew J.;
- Yancopoulos, George D.;
- Gale, Nicholas W.;
- Takahashi, Takamune
Publication type:
Article

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