Works matching AU Valenti, Melanie

Results: 14

FGF7--FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas.

Published in:

Molecular Oncology, 2022, v. 16, n. 6, p. 1272, doi. 10.1002/1878-0261.13145

By:

Milton, Christopher I.;
Selfe, Joanna;
Aladowicz, Ewa;
Man, Stella Y. K.;
Bernauer, Carolina;
Missiaglia, Edoardo;
Walters, Zoë S.;
Gatz, Susanne A.;
Kelsey, Anna;
Generali, Melanie;
Box, Gary;
Valenti, Melanie;
de Haven-Brandon, Alexis;
Galiwango, David;
Hayes, Angela;
Clarke, Matthew;
Izquierdo, Elisa;
Gonzalez De Castro, David;
Raynaud, Florence I.;
Kirkin, Vladimir

Publication type:

Article

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy.

Published in:

2017

By:

Faisal, Amir;
Mak, Grace W Y;
Gurden, Mark D;
Xavier, Cristina P R;
Anderhub, Simon J;
Innocenti, Paolo;
Westwood, Isaac M;
Naud, Sébastien;
Hayes, Angela;
Box, Gary;
Valenti, Melanie R;
De Haven Brandon, Alexis K;
O'Fee, Lisa;
Schmitt, Jessica;
Woodward, Hannah L;
Burke, Rosemary;
vanMontfort, Rob L M;
Blagg, Julian;
Raynaud, Florence I;
Eccles, Suzanne A

Publication type:

journal article

Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma.

Published in:

2020

By:

Poon, Evon;
Liang, Tong;
Jamin, Yann;
Walz, Susanne;
Kwok, Colin;
Hakkert, Anne;
Barker, Karen;
Urban, Zuzanna;
Thway, Khin;
Zeid, Rhamy;
Hallsworth, Albert;
Box, Gary;
Ebus, Marli E.;
Licciardello, Marco P.;
Sbirkov, Yordan;
Lazaro, Glori;
Calton, Elizabeth;
Costa, Barbara M.;
Valenti, Melanie;
De Haven Brandon, Alexis

Publication type:

journal article

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Correction Notice

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A;
Judson, Ian;
Jackman, Ann L;
Workman, Paul

Publication type:

corrected article

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 769, doi. 10.1007/s00280-007-0662-x

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Article

ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0420-8

By:

Carvalho, Diana;
Taylor, Kathryn R.;
Olaciregui, Nagore Gene;
Molinari, Valeria;
Clarke, Matthew;
Mackay, Alan;
Ruddle, Ruth;
Henley, Alan;
Valenti, Melanie;
Hayes, Angela;
Brandon, Alexis De Haven;
Eccles, Suzanne A.;
Raynaud, Florence;
Boudhar, Aicha;
Monje, Michelle;
Popov, Sergey;
Moore, Andrew S.;
Mora, Jaume;
Cruz, Ofelia;
Vinci, Mara

Publication type:

Article

Application of Meso Scale Technology for the Measurement of Phosphoproteins in Human Tumor Xenografts.

Published in:

Assay & Drug Development Technologies, 2007, v. 5, n. 3, p. 391, doi. 10.1089/adt.2006.044

By:

Sharon M. Gowan;
Anthea Hardcastle;
Albert E. Hallsworth;
Melanie R. Valenti;
Lisa-Jane K. Hunter;
Alexis K. de Haven Brandon;
Michelle D. Garrett;
Florence Raynaud;
Paul Workman;
Wynne Aherne;
Suzanne A. Eccles

Publication type:

Article

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy.

Published in:

Autophagy, 2020, v. 16, n. 6, p. 1044, doi. 10.1080/15548627.2019.1659608

By:

Andrejeva, Gabriela;
Gowan, Sharon;
Lin, Gigin;
Wong Te Fong, Anne-Christine LF;
Shamsaei, Elham;
Parkes, Harry G.;
Mui, James;
Raynaud, Florence I.;
Asad, Yasmin;
Vizcay-Barrena, Gema;
Nikitorowicz-Buniak, Joanna;
Valenti, Melanie;
Howell, Louise;
Fleck, Roland A.;
Martin, Lesley-Ann;
Kirkin, Vladimir;
Leach, Martin O.;
Chung, Yuen-Li

Publication type:

Article

Overexpression of Bcl.

Published in:

International Journal of Cancer, 2002, v. 97, n. 6, p. 858, doi. 10.1002/ijc.10132

By:

Rogers, Paul M.;
Beale, Philip J.;
Al-Moundhri, Mansour;
Boxall, Frances;
Patterson, Lisa;
Valenti, Melanie;
Raynaud, Florence;
Hobbs, Steve;
Johnston, Stephen;
Kelland, Lloyd R.

Publication type:

Article

Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma.

Published in:

Cell Cycle, 2009, v. 8, n. 3, p. 443, doi. 10.4161/cc.8.3.7643

By:

Guillard, Sandrine;
Clarke, Paul A.;
Poele, Robert te;
Mohri, Zahra;
Bjerke, Lynn;
Valenti, Melanie;
Raynaud, Florence;
Eccles, Suzanne A.;
Workman, Paul

Publication type:

Article

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.

Published in:

Nature Chemical Biology, 2015, v. 11, n. 12, p. 973, doi. 10.1038/nchembio.1952

By:

Dale, Trevor;
Clarke, Paul A;
Esdar, Christina;
Waalboer, Dennis;
Adeniji-Popoola, Olajumoke;
Ortiz-Ruiz, Maria-Jesus;
Mallinger, Aurélie;
Samant, Rahul S;
Czodrowski, Paul;
Musil, Djordje;
Schwarz, Daniel;
Schneider, Klaus;
Stubbs, Mark;
Ewan, Ken;
Fraser, Elizabeth;
TePoele, Robert;
Court, Will;
Box, Gary;
Valenti, Melanie;
de Haven Brandon, Alexis

Publication type:

Article

Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1α and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypoxia.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 8, p. 2243, doi. 10.1128/MCB.00959-08

By:

Yang, Jun;
Ahmed, Afshan;
Poon, Evon;
Perusinghe, Nina;
Brandon, Alexis de Haven;
Box, Gary;
Valenti, Melanie;
Eccles, Suzanne;
Rouschop, Kasper;
Wouters, Brad;
Ashcroft, Margaret

Publication type:

Article

Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67533-1

By:

De Haven Brandon, Alexis;
Box, Gary;
Hallsworth, Albert;
Court, William;
Matthews, Nicoll;
Herodek, Balint;
Arteagabeitia, Aitor Bermejo;
Valenti, Melanie;
Kirkin, Vladimir

Publication type:

Article