Works by VIÑUELA, ANA

Results: 31
    1

    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts.

    Published in:
    PLoS Medicine, 2020, v. 17, n. 6, p. 1, doi. 10.1371/journal.pmed.1003149
    By:
    • Atabaki-Pasdar, Naeimeh;
    • Ohlsson, Mattias;
    • Viñuela, Ana;
    • Frau, Francesca;
    • Pomares-Millan, Hugo;
    • Haid, Mark;
    • Jones, Angus G.;
    • Thomas, E. Louise;
    • Koivula, Robert W.;
    • Kurbasic, Azra;
    • Mutie, Pascal M.;
    • Fitipaldi, Hugo;
    • Fernandez, Juan;
    • Dawed, Adem Y.;
    • Giordano, Giuseppe N.;
    • Forgie, Ian M.;
    • McDonald, Timothy J.;
    • Rutters, Femke;
    • Cederberg, Henna;
    • Chabanova, Elizaveta
    Publication type:
    Article
    2

    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts.

    Published in:
    2020
    By:
    • Atabaki-Pasdar, Naeimeh;
    • Ohlsson, Mattias;
    • Viñuela, Ana;
    • Frau, Francesca;
    • Pomares-Millan, Hugo;
    • Haid, Mark;
    • Jones, Angus G;
    • Thomas, E Louise;
    • Koivula, Robert W;
    • Kurbasic, Azra;
    • Mutie, Pascal M;
    • Fitipaldi, Hugo;
    • Fernandez, Juan;
    • Dawed, Adem Y;
    • Giordano, Giuseppe N;
    • Forgie, Ian M;
    • McDonald, Timothy J;
    • Rutters, Femke;
    • Cederberg, Henna;
    • Chabanova, Elizaveta
    Publication type:
    journal article
    3
    4
    5

    Differential Expression Analyses on Human Aortic Tissue Reveal Novel Genes and Pathways Associated With Abdominal Aortic Aneurysm Onset and Progression.

    Published in:
    Journal of the American Heart Association, 2024, v. 13, n. 24, p. 1, doi. 10.1161/JAHA.124.036082
    By:
    • Temprano-Sagrera, Gerard;
    • Peypoch, Olga;
    • Soto, Begoña;
    • Dilmé, Jaume;
    • Calsina Juscafresa, Laura;
    • Davtian, David;
    • de la Rosa Estadella, Mireia;
    • Nieto, Lluís;
    • Brown, Andrew;
    • Escudero, José Román;
    • Viñuela, Ana;
    • Camacho, Mercedes;
    • Sabater-Lleal, Maria
    Publication type:
    Article
    6
    7

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.

    Published in:
    Diabetologia, 2019, v. 62, n. 9, p. 1601, doi. 10.1007/s00125-019-4906-1
    By:
    • Koivula, Robert W.;
    • Forgie, Ian M.;
    • Kurbasic, Azra;
    • Viñuela, Ana;
    • Heggie, Alison;
    • Giordano, Giuseppe N.;
    • Hansen, Tue H.;
    • Hudson, Michelle;
    • Koopman, Anitra D. M.;
    • Rutters, Femke;
    • Siloaho, Maritta;
    • Allin, Kristine H.;
    • Brage, Søren;
    • Brorsson, Caroline A.;
    • Dawed, Adem Y.;
    • De Masi, Federico;
    • Groves, Christopher J.;
    • Kokkola, Tarja;
    • Mahajan, Anubha;
    • Perry, Mandy H.
    Publication type:
    Article
    8

    An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins.

    Published in:
    Nature Communications, 2014, v. 5, n. 12, p. 5719, doi. 10.1038/ncomms6719
    By:
    • Yuan, Wei;
    • Xia, Yudong;
    • Bell, Christopher G.;
    • Yet, Idil;
    • Ferreira, Teresa;
    • Ward, Kirsten J.;
    • Gao, Fei;
    • Loomis, A. Katrina;
    • Hyde, Craig L.;
    • Wu, Honglong;
    • Lu, Hanlin;
    • Liu, Yuan;
    • Small, Kerrin S.;
    • Viñuela, Ana;
    • Morris, Andrew P.;
    • Berdasco, María;
    • Esteller, Manel;
    • Brosnan, M. Julia;
    • Deloukas, Panos;
    • McCarthy, Mark I.
    Publication type:
    Article
    9

    Gene expression changes with age in skin, adipose tissue, blood and brain.

    Published in:
    Genome Biology, 2013, v. 14, n. 7, p. R75, doi. 10.1186/gb-2013-14-7-r75
    By:
    • Glass, Daniel;
    • Viñuela, Ana;
    • Davies, Matthew N;
    • Ramasamy, Adaikalavan;
    • Parts, Leopold;
    • Knowles, David;
    • Brown, Andrew A;
    • Hedman, Åsa K;
    • Small, Kerrin S;
    • Buil, Alfonso;
    • Grundberg, Elin;
    • Nica, Alexandra C;
    • Nestle, Frank O;
    • Ryten, Mina;
    • the UK Brain Expression consortium;
    • the MuTHER consortium;
    • Durbin, Richard;
    • McCarthy, Mark I;
    • Deloukas, Panagiotis;
    • Dermitzakis, Emmanouil T
    Publication type:
    Article
    10
    11

    A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

    Published in:
    2017
    By:
    • Manning, Alisa;
    • Highland, Heather M.;
    • Gasser, Jessica;
    • Sim, Xueling;
    • Tukiainen, Taru;
    • Fontanillas, Pierre;
    • Grarup, Niels;
    • Rivas, Manuel A.;
    • Mahajan, Anubha;
    • Locke, Adam E.;
    • Cingolani, Pablo;
    • Pers, Tune H.;
    • Viñuela, Ana;
    • Brown, Andrew A.;
    • Ying Wu;
    • Flannick, Jason;
    • Fuchsberger, Christian;
    • Gamazon, Eric R.;
    • Gaulton, Kyle J.;
    • Hae Kyung Im
    Publication type:
    journal article
    12
    13
    14

    Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18581-8
    By:
    • Viñuela, Ana;
    • Varshney, Arushi;
    • van de Bunt, Martijn;
    • Prasad, Rashmi B.;
    • Asplund, Olof;
    • Bennett, Amanda;
    • Boehnke, Michael;
    • Brown, Andrew A.;
    • Erdos, Michael R.;
    • Fadista, João;
    • Hansson, Ola;
    • Hatem, Gad;
    • Howald, Cédric;
    • Iyengar, Apoorva K.;
    • Johnson, Paul;
    • Krus, Ulrika;
    • MacDonald, Patrick E.;
    • Mahajan, Anubha;
    • Manning Fox, Jocelyn E.;
    • Narisu, Narisu
    Publication type:
    Article
    15
    16
    17
    18
    19

    Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.

    Published in:
    2021
    By:
    • Tura, Andrea;
    • Grespan, Eleonora;
    • Göbl, Christian S.;
    • Koivula, Robert W.;
    • Franks, Paul W.;
    • Pearson, Ewan R.;
    • Walker, Mark;
    • Forgie, Ian M.;
    • Giordano, Giuseppe N.;
    • Pavo, Imre;
    • Ruetten, Hartmut;
    • Dermitzakis, Emmanouil T.;
    • McCarthy, Mark I.;
    • Pedersen, Oluf;
    • Schwenk, Jochen M.;
    • Adamski, Jerzy;
    • De Masi, Federico;
    • Tsirigos, Konstantinos D.;
    • Brunak, Søren;
    • Viñuela, Ana
    Publication type:
    journal article
    20
    21
    22
    23
    24

    Circulating Proteomic Signatures of Chronological Age.

    Published in:
    2015
    By:
    • Menni, Cristina;
    • Kiddle, Steven J;
    • Mangino, Massimo;
    • Viñuela, Ana;
    • Psatha, Maria;
    • Steves, Claire;
    • Sattlecker, Martina;
    • Buil, Alfonso;
    • Newhouse, Stephen;
    • Nelson, Sally;
    • Williams, Stephen;
    • Voyle, Nicola;
    • Soininen, Hilkka;
    • Kloszewska, Iwona;
    • Mecocci, Patrizia;
    • Tsolaki, Magda;
    • Vellas, Bruno;
    • Lovestone, Simon;
    • Spector, Tim D;
    • Dobson, Richard
    Publication type:
    journal article
    25
    26
    27

    Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.

    Published in:
    Human Molecular Genetics, 2012, v. 21, n. 24, p. 5385, doi. 10.1093/hmg/dds382
    By:
    • Mangino, Massimo;
    • Hwang, Shih-Jen;
    • Spector, Timothy D.;
    • Hunt, Steven C.;
    • Kimura, Masayuki;
    • Fitzpatrick, Annette L.;
    • Christiansen, Lene;
    • Petersen, Inge;
    • Elbers, Clara C.;
    • Harris, Tamara;
    • Chen, Wei;
    • Srinivasan, Sathanur R.;
    • Kark, Jeremy D.;
    • Benetos, Athanase;
    • El Shamieh, Said;
    • Visvikis-Siest, Sophie;
    • Christensen, Kaare;
    • Berenson, Gerald S.;
    • Valdes, Ana M.;
    • Viñuela, Ana
    Publication type:
    Article
    28

    Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health.

    Published in:
    Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0558-0
    By:
    • Tsai, Pei-Chien;
    • Glastonbury, Craig A.;
    • Eliot, Melissa N.;
    • Bollepalli, Sailalitha;
    • Yet, Idil;
    • Castillo-Fernandez, Juan E.;
    • Carnero-Montoro, Elena;
    • Hardiman, Thomas;
    • Martin, Tiphaine C.;
    • Vickers, Alice;
    • Mangino, Massimo;
    • Ward, Kirsten;
    • Pietiläinen, Kirsi H.;
    • Deloukas, Panos;
    • Spector, Tim D.;
    • Viñuela, Ana;
    • Loucks, Eric B.;
    • Ollikainen, Miina;
    • Kelsey, Karl T.;
    • Small, Kerrin S.
    Publication type:
    Article
    29

    Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.

    Published in:
    Epigenetics, 2014, v. 9, n. 10, p. 1382, doi. 10.4161/15592294.2014.969637
    By:
    • Tsaprouni, Loukia G;
    • Yang, Tsun-Po;
    • Bell, Jordana;
    • Dick, Katherine J;
    • Kanoni, Stavroula;
    • Nisbet, James;
    • Viñuela, Ana;
    • Grundberg, Elin;
    • Nelson, Christopher P;
    • Meduri, Eshwar;
    • Buil, Alfonso;
    • Cambien, Francois;
    • Hengstenberg, Christian;
    • Erdmann, Jeanette;
    • Schunkert, Heribert;
    • Goodall, Alison H;
    • Ouwehand, Willem H;
    • Dermitzakis, Emmanouil;
    • Spector, Tim D;
    • Samani, Nilesh J
    Publication type:
    Article
    30

    The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 9, p. e1697, doi. 10.1210/clinem/dgae119
    By:
    • Eriksen, Rebeca;
    • White, Margaret C;
    • Dawed, Adem Y;
    • Perez, Isabel Garcia;
    • Posma, Joram M;
    • Haid, Mark;
    • Sharma, Sapna;
    • Prehn, Cornelia;
    • Thomas, E Louise;
    • Koivula, Robert W;
    • Bizzotto, Roberto;
    • Mari, Andrea;
    • Giordano, Giuseppe N;
    • Pavo, Imre;
    • Schwenk, Jochen M;
    • Masi, Federico De;
    • Tsirigos, Konstantinos D;
    • Brunak, Søren;
    • Viñuela, Ana;
    • Mahajan, Anubha
    Publication type:
    Article
    31

    Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.

    Published in:
    2021
    By:
    • Deshmukh, Harshal A;
    • Madsen, Anne Lundager;
    • Viñuela, Ana;
    • Have, Christian Theil;
    • Grarup, Niels;
    • Tura, Andrea;
    • Mahajan, Anubha;
    • Heggie, Alison J;
    • Koivula, Robert W;
    • De Masi, Federico;
    • Tsirigos, Konstantinos K;
    • Linneberg, Allan;
    • Drivsholm, Thomas;
    • Pedersen, Oluf;
    • Sørensen, Thorkild I A;
    • Astrup, Arne;
    • Gjesing, Anette A P;
    • Pavo, Imre;
    • Wood, Andrew R;
    • Ruetten, Hartmut
    Publication type:
    journal article