Found: 43
Select item for more details and to access through your institution.
Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Hepatic Gene Expression Changes in an Experimental Model of Accelerated Senescence: The SAM-P8 Mouse.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 10, p. 1043, doi. 10.1093/gerona/63.10.1043
- By:
- Publication type:
- Article
Peroxisome Proliferator-Activated Receptor α Down-Regulation Is Associated With Enhanced Ceramide Levels in Age-Associated Cardiac Hypertrophy.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 12, p. 1326, doi. 10.1093/gerona/62.12.1326
- By:
- Publication type:
- Article
Hypertriglyceridemia and Hepatic Steatosis in Senescence-Accelerated Mouse Associate to Changes in Lipid-Related Gene Expression.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 11, p. 1219, doi. 10.1093/gerona/62.11.1219
- By:
- Publication type:
- Article
Peroxisomal Proliferator-Activated Receptor ß/d Deficiency Induces Cognitive Alterations.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.902047
- By:
- Publication type:
- Article
PPARs as Key Mediators in the Regulation of Metabolism and Inflammation.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 5025, doi. 10.3390/ijms23095025
- By:
- Publication type:
- Article
The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8555, doi. 10.3390/ijms22168555
- By:
- Publication type:
- Article
PPAR βδ: A Key Therapeutic Target in Metabolic Disorders.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 913, doi. 10.3390/ijms19030913
- By:
- Publication type:
- Article
SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation.
- Published in:
- Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-0114-1
- By:
- Publication type:
- Article
VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells.
- Published in:
- Diabetologia, 2017, v. 60, n. 11, p. 2262, doi. 10.1007/s00125-017-4401-5
- By:
- Publication type:
- Article
PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
- Published in:
- Diabetologia, 2014, v. 57, n. 10, p. 2126, doi. 10.1007/s00125-014-3331-8
- By:
- Publication type:
- Article
PGC-1α Induces Mitochondrial and Myokine Transcriptional Programs and Lipid Droplet and Glycogen Accumulation in Cultured Human Skeletal Muscle Cells.
- Published in:
- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029985
- By:
- Publication type:
- Article
The Interplay between NF-kappaB and E2F1 Coordinately Regulates Inflammation and Metabolism in Human Cardiac Cells.
- Published in:
- PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019724
- By:
- Publication type:
- Article
CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.
- Published in:
- Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01352-5
- By:
- Publication type:
- Article
CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.
- Published in:
- Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01352-5
- By:
- Publication type:
- Article
The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells.
- Published in:
- Cardiovascular Research, 2010, v. 87, n. 3, p. 449, doi. 10.1093/cvr/cvq080
- By:
- Publication type:
- Article
TNF-{alpha} reduces PGC-1{alpha} expression through NF-{kappa}B and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model.
- Published in:
- Cardiovascular Research, 2009, v. 81, n. 4, p. 703, doi. 10.1093/cvr/cvn327
- By:
- Publication type:
- Article
Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages
- Published in:
- Cardiovascular Research, 2005, v. 66, n. 1, p. 141, doi. 10.1016/j.cardiores.2004.12.024
- By:
- Publication type:
- Article
Peroxisome proliferator-activated receptor β/δ activation inhibits hypertrophy in neonatal rat cardiomyocytes
- Published in:
- Cardiovascular Research, 2005, v. 65, n. 4, p. 832, doi. 10.1016/j.cardiores.2004.11.011
- By:
- Publication type:
- Article
Design and Synthesis of AMPK Activators and GDF15 Inducers.
- Published in:
- Molecules, 2023, v. 28, n. 14, p. 5468, doi. 10.3390/molecules28145468
- By:
- Publication type:
- Article
SIRT1 regulates hepatic vldlr levels.
- Published in:
- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01666-y
- By:
- Publication type:
- Article
GADD45A: With or without you.
- Published in:
- Medicinal Research Reviews, 2024, v. 44, n. 4, p. 1375, doi. 10.1002/med.22015
- By:
- Publication type:
- Article
CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.634797
- By:
- Publication type:
- Article
AICAR Protects against High Palmitate/High Insulin-Induced Intramyocellular Lipid Accumulation and Insulin Resistance in HL-1 Cardiac Cells by Inducing PPAR-Target Gene Expression.
- Published in:
- PPAR Research, 2015, p. 1, doi. 10.1155/2015/785783
- By:
- Publication type:
- Article
The Role of Peroxisome Proliferator-Activated Receptor ß/δ on the Inflammatory Basis of Metabolic Disease.
- Published in:
- PPAR Research, 2010, p. 1, doi. 10.1155/2010/368467
- By:
- Publication type:
- Article
Role of brain c‐Jun N‐terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high‐fat diet pre‐clinical model.
- Published in:
- Journal of Neurochemistry, 2019, v. 149, n. 2, p. 255, doi. 10.1111/jnc.14682
- By:
- Publication type:
- Article
Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients.
- Published in:
- European Journal of Clinical Pharmacology, 2004, v. 59, n. 12, p. 855, doi. 10.1007/s00228-003-0704-1
- By:
- Publication type:
- Article
PGC-1beta down-regulation is associated with reduced ERRalpha activity and MCAD expression in skeletal muscle of senescence-accelerated mice.
- Published in:
- 2006
- By:
- Publication type:
- journal article
PGC-1ß Down-Regulation Is Associated With Reduced ERRα Activity and MCAD Expression in Skeletal Muscle of Senescence-Accelerated Mice.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2006, v. 61, n. 8, p. 773, doi. 10.1093/gerona/61.8.773
- By:
- Publication type:
- Article
Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes.
- Published in:
- Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/381815
- By:
- Publication type:
- Article
Activation of Peroxisome Proliferator-Activated Receptor β/σ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-κB Activity via Extracellular Signal-Related Kinase 1/2.
- Published in:
- Diabetes, 2008, v. 57, n. 8, p. 2149, doi. 10.2337/db08-0176
- By:
- Publication type:
- Article
Palmitate-Mediated Downregulation of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α in Skeletal Muscle Cells Involves MEK1/2 and Nuclear Factor-κB Activation.
- Published in:
- Diabetes, 2006, v. 55, n. 10, p. 2779, doi. 10.2337/db05-1494
- By:
- Publication type:
- Article
Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.
- Published in:
- Clinical Science, 2015, v. 129, n. 9, p. 823, doi. 10.1042/CS20150111
- By:
- Publication type:
- Article
Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity.
- Published in:
- Acta Diabetologica, 2016, v. 53, n. 1, p. 109, doi. 10.1007/s00592-015-0759-3
- By:
- Publication type:
- Article
PPARs as Key Transcription Regulators at the Crossroads of Metabolism and Inflammation.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4467, doi. 10.3390/ijms25084467
- By:
- Publication type:
- Article
Deletion of Gadd45a Expression in Mice Leads to Cognitive and Synaptic Impairment Associated with Alzheimer's Disease Hallmarks.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2595, doi. 10.3390/ijms25052595
- By:
- Publication type:
- Article
Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 9, p. 7327, doi. 10.1007/s12035-018-0868-4
- By:
- Publication type:
- Article
Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Activation of Peroxisome Proliferator-Activated Receptor-β/-δ Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6-Stimulated Adipocytes.
- Published in:
- Diabetes, 2011, v. 60, n. 7, p. 1990, doi. 10.2337/db10-0704
- By:
- Publication type:
- Article
Endoplasmic reticulum stress downregulates PGC-1α in skeletal muscle through ATF4 and an mTOR-mediated reduction of CRTC2.
- Published in:
- Cell Communication & Signaling, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12964-022-00865-9
- By:
- Publication type:
- Article
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2.
- Published in:
- Cell Communication & Signaling, 2020, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12964-020-00640-8
- By:
- Publication type:
- Article