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The Impact of Antidiabetic Therapies on Diastolic Dysfunction and Diabetic Cardiomyopathy.
- Published in:
- Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.603247
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- Article
Myocardial Energy Metabolism in Non-ischemic Cardiomyopathy.
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- Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.570421
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- Article
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure.
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- Cardiovascular Diabetology, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12933-019-0892-3
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- Article
Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction.
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- Cardiovascular Diabetology, 2019, v. 18, n. 1, p. 1, doi. 10.1186/s12933-019-0806-4
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- Article
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.
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- Cardiovascular Diabetology, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12933-023-01811-w
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- Article
Metabolic, structural and biochemical changes in diabetes and the development of heart failure.
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- Diabetologia, 2022, v. 65, n. 3, p. 411, doi. 10.1007/s00125-021-05637-7
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- Article
Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.
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- Diabetologia, 2018, v. 61, n. 8, p. 1849, doi. 10.1007/s00125-018-4643-x
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- Article
Inhibition of Serine Palmitoyl Transferase I Reduces Cardiac Ceramide Levels and Increases Glycolysis Rates following Diet-Induced Insulin Resistance.
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037703
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- Article
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.
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- Cardiovascular Research, 2019, v. 115, n. 11, p. 1606, doi. 10.1093/cvr/cvz045
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- Article
Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation.
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- Cardiovascular Research, 2014, v. 101, n. 1, p. 30, doi. 10.1093/cvr/cvt216
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- Article
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury.
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- Cardiovascular Research, 2012, v. 94, n. 2, p. 359, doi. 10.1093/cvr/cvs129
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- Publication type:
- Article
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation.
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- Cardiovascular Research, 2011, v. 89, n. 1, p. 148, doi. 10.1093/cvr/cvq266
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- Article
The malonyl CoA axis as a potential target for treating ischaemic heart disease.
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- Cardiovascular Research, 2008, v. 79, n. 2, p. 259, doi. 10.1093/cvr/cvn130
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- Publication type:
- Article
The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischaemic heart failure.
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- Cardiovascular Research, 2024, v. 120, n. 10, p. 1126, doi. 10.1093/cvr/cvae092
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- Article
Ketones can become the major fuel source for the heart but do not increase cardiac efficiency.
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- Cardiovascular Research, 2021, v. 117, n. 4, p. 1178, doi. 10.1093/cvr/cvaa143
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- Article
l‐Citrulline supplementation improves glucose and exercise tolerance in obese male mice.
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- Experimental Physiology, 2020, v. 105, n. 2, p. 270, doi. 10.1113/EP088109
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- Publication type:
- Article
Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity.
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- Science Translational Medicine, 2019, v. 11, n. 478, p. N.PAG, doi. 10.1126/scitranslmed.aau8866
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- Publication type:
- Article
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy.
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- Journal of the American Heart Association, 2024, v. 13, n. 7, p. 1, doi. 10.1161/JAHA.123.032697
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- Article
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes.
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- 2021
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- Publication type:
- journal article
The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes.
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- Canadian Journal of Physiology & Pharmacology, 2022, v. 100, n. 5, p. 393, doi. 10.1139/cjpp-2021-0559
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- Publication type:
- Article
Female offspring born to obese and insulin-resistant dams are not at increased risk for obesity and metabolic dysfunction during early development.
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- Canadian Journal of Physiology & Pharmacology, 2018, v. 96, n. 1, p. 97, doi. 10.1139/cjpp-2017-0371
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- Article
5′-AMP-activated protein kinase increases glucose uptake independent of GLUT4 translocation in cardiac myocytes.
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- Canadian Journal of Physiology & Pharmacology, 2014, v. 92, n. 4, p. 307, doi. 10.1139/cjpp-2013-0107
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- Publication type:
- Article
Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat.
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- Experimental Physiology, 2015, v. 100, n. 6, p. 730, doi. 10.1113/EP085052
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- Article
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48955-1
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- Article
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48955-1
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- Article
New Therapeutic Options for Type 2 Diabetes Mellitus and Their Impact Against Ischemic Heart Disease.
- Published in:
- Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.904626
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- Publication type:
- Article
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.
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- Science Translational Medicine, 2022, v. 14, n. 669, p. 1, doi. 10.1126/scitranslmed.abm3565
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- Article
Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion.
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- Basic Research in Cardiology, 2009, v. 104, n. 2, p. 203, doi. 10.1007/s00395-009-0003-9
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- Article
The antianginal ranolazine fails to improve glycaemia in obese liver‐specific pyruvate dehydrogenase deficient male mice.
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- Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 2, p. 194, doi. 10.1111/bcpt.13906
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- Article
Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Considering the Effect on Skeletal Muscle Metabolism.
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- Nutrients, 2023, v. 15, n. 19, p. 4228, doi. 10.3390/nu15194228
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- Article
The Relationship Between Cardiac Energy Metabolism and Cardiac Function in Obesity and Type 2 Diabetes: Revisiting a 2003 Diabetes Classic by Aasum et al.
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- Diabetes, 2024, v. 73, n. 9, p. 1373, doi. 10.2337/dbi24-0029
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- Article
Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology.
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- Diabetes, 2024, v. 73, n. 5, p. 659, doi. 10.2337/dbi23-0019
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- Publication type:
- Article
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
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- Diabetes, 2023, v. 72, n. 1, p. 126, doi. 10.2337/db22-0221
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- Article
GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue.
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- 2022
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- Publication type:
- journal article
Cardiovascular Effects of Incretin-Based Therapies: Integrating Mechanisms With Cardiovascular Outcome Trials.
- Published in:
- 2022
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- Publication type:
- journal article
379-P: Aldose Reductase Inhibition by AT-001 Prevents Diabetic Cardiomyopathy via Reducing Myocardial Fatty Acid Oxidation Rates.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-379-P
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- Publication type:
- Article
34-OR: Maladaptive Increases in Skeletal Muscle Ketone Body Oxidation Contribute to Dysglycemia in Mice Subjected to Experimental Obesity.
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- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-34-OR
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- Publication type:
- Article
Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice.
- Published in:
- 2016
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- Publication type:
- journal article
Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.
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- 2016
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- Publication type:
- journal article
Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice.
- Published in:
- Diabetes, 2013, v. 62, n. 3, p. 711, doi. 10.2337/db12-0259
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- Publication type:
- Article
Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice.
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- 2012
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- Publication type:
- journal article
Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr<sup>-/-</sup> Mice.
- Published in:
- Diabetes, 2012, v. 61, n. 1, p. 40, doi. 10.2337/db11-1060
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- Publication type:
- Article
Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption.
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- Diabetes, 2010, v. 59, n. 10, p. 2453, doi. 10.2337/db09-1293
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- Publication type:
- Article
Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet-Induced Obese Mice Lacking Malonyl CoA Decarboxylase.
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- Diabetes, 2009, v. 58, n. 8, p. 1766, doi. 10.2337/db09-0011
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- Publication type:
- Article