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A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13602, doi. 10.3390/ijms222413602
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- Article
miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8675, doi. 10.3390/ijms21228675
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- Article
Pathophysiology of Type 2 Diabetes Mellitus.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6275, doi. 10.3390/ijms21176275
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- Article
Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 13, p. 4725, doi. 10.3390/ijms21134725
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- Article
Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3426, doi. 10.3390/ijms19113426
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- Article
Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1676, doi. 10.3390/ijms19061676
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- Article
Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells.
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- Scientific Reports, 2015, p. 13774, doi. 10.1038/srep13774
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- Article
Ca<sup>2+</sup> Influx and Tyrosine Kinases Trigger <i>Bordetella</i> Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression of the CD11b/CD18 Integrin Major Determinants of the Entry Route.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074248
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- Article
Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067648
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- Article
Adenylate Cyclase Toxin Promotes Internalisation of Integrins and Raft Components and Decreases Macrophage Adhesion Capacity.
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- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017383
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- Article
Predictive Modeling and Structure Analysis of Genetic Variants in Familial Hypercholesterolemia: Implications for Diagnosis and Protein Interaction Studies.
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- Current Atherosclerosis Reports, 2023, v. 25, n. 11, p. 839, doi. 10.1007/s11883-023-01154-7
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- Article
Membrane Permeabilization by Bordetella Adenylate Cyclase Toxin Involves Pores of Tunable Size.
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- Biomolecules (2218-273X), 2019, v. 9, n. 5, p. 183, doi. 10.3390/biom9050183
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- Article
Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size.
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- FEBS Journal, 2021, v. 288, n. 23, p. 6795, doi. 10.1111/febs.16107
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- Article
OptiMo‐LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues.
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- Advanced Science, 2024, v. 11, n. 13, p. 1, doi. 10.1002/advs.202305177
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- Article
Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-58734-9
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- Article
Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple‐Cell 2D Atherosclerosis Model.
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- Small, 2022, v. 18, n. 13, p. 1, doi. 10.1002/smll.202105915
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- Article
Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?
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- Toxins, 2019, v. 11, n. 6, p. 354, doi. 10.3390/toxins11060354
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Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes.
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- Toxins, 2017, v. 9, n. 10, p. 295, doi. 10.3390/toxins9100295
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- Article
Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition.
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- Biomedicines, 2020, v. 8, n. 10, p. 373, doi. 10.3390/biomedicines8100373
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Functional characterization of splicing and ligand-binding domain variants in the LDL receptor.
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- Human Mutation, 2012, v. 33, n. 1, p. 232, doi. 10.1002/humu.21630
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Decellularization of xenografted tumors provides cell-specific in vitro 3D environment.
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- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.956940
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- Article