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A home run for human NaCT/SLC13A5/INDY: cryo-EM structure and homology model to predict transport mechanisms, inhibitor interactions and mutational defects.
- Published in:
- Biochemical Journal, 2021, v. 478, n. 11, p. 2051, doi. 10.1042/BCJ20210211
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Functional analysis of a species-specific inhibitor selective for human Na<sup>+</sup>-coupled citrate transporter (NaCT/SLC13A5/mINDY).
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- Biochemical Journal, 2020, v. 477, n. 21, p. 4149, doi. 10.1042/BCJ20200592
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- Article
Drosophila INDY and Mammalian INDY: Major Differences in Transport Mechanism and Structural Features despite Mostly Similar Biological Functions.
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- Metabolites (2218-1989), 2021, v. 11, n. 10, p. 669, doi. 10.3390/metabo11100669
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- Article
Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae.
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- Scientific Reports, 2016, p. 31443, doi. 10.1038/srep31443
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- Article
A Gene Optimization Strategy that Enhances Production of Fully Functional P-Glycoprotein in Pichia pastoris.
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- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022577
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- Article
Directed evolution of P-glycoprotein cysteines reveals site-specific, non-conservative substitutions that preserve multidrug resistance.
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- Bioscience Reports, 2014, v. 34, n. 3, p. 297, doi. 10.1042/BSR20140062
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- Article
Design and Synthesis of Selenazole-Containing Peptides for Cocrystallization with P-Glycoprotein.
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- ChemBioChem, 2011, v. 12, n. 6, p. 868, doi. 10.1002/cbic.201100048
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- Article
Replacing the eleven native tryptophans by directed evolution produces an active P-glycoprotein with site-specific, non-conservative substitutions.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-59802-w
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- Article
Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3)
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- FEBS Letters, 2007, v. 581, n. 2, p. 301, doi. 10.1016/j.febslet.2006.12.030
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- Article
Nucleotide Binding to the Human Multidrug Resistance Protein 3, MRP3.
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- Protein Journal, 2010, v. 29, n. 5, p. 373, doi. 10.1007/s10930-010-9262-4
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- Article
Antigen-specific therapy of experimental myasthenia gravis with acetylcholine receptor-gelonin conjugates in vivo.
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- European Journal of Immunology, 1993, v. 23, n. 3, p. 776, doi. 10.1002/eji.1830230332
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- Article
Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains.
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- Protein Science: A Publication of the Protein Society, 2014, v. 23, n. 6, p. 769, doi. 10.1002/pro.2460
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- Article