Works by Urano, Fumihiko
Results: 65
Dominant ER Stress-Inducing Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
- Published in:
- 2017
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- Publication type:
- journal article
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
- Published in:
- Nature Cell Biology, 2000, v. 2, n. 12, p. 863, doi. 10.1038/35046500
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- Publication type:
- Article
High frequency of inactivation of the imprinted H19 gene in 'sporadic' hepatoblastoma.
- Published in:
- International Journal of Cancer, 1999, v. 82, n. 4, p. 490, doi. 10.1002/(SICI)1097-0215(19990812)82:4<490::AID-IJC4>3.0.CO;2-I
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- Publication type:
- Article
Wolfram Syndrome: Diagnosis, Management, and Treatment.
- Published in:
- Current Diabetes Reports, 2016, v. 16, n. 1, p. 1, doi. 10.1007/s11892-015-0702-6
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- Publication type:
- Article
Male sterility and enhanced radiation sensitivity in TLS<sup>-/-</sup> mice.
- Published in:
- EMBO Journal, 2000, v. 19, n. 3, p. 453, doi. 10.1093/emboj/19.3.453
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- Publication type:
- Article
Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41604-4
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- Publication type:
- Article
Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ<sup>null</sup> mice treated with alogliptin.
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- Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2013, v. 6, p. 493, doi. 10.2147/DMSO.S53154
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- Publication type:
- Article
Establishment and Characterization of a Clonal Human Extraskeletal Ewing's Sarcoma Cell Line, EES1.
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- Tohoku Journal of Experimental Medicine, 2006, v. 210, n. 3, p. 221, doi. 10.1620/tjem.210.221
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- Publication type:
- Article
FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress.
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- Journal of Cellular Physiology, 2013, v. 228, n. 11, p. 2222, doi. 10.1002/jcp.24395
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- Publication type:
- Article
The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death.
- Published in:
- 2008
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- Publication type:
- journal article
The Role of Nitric Oxide and the Unfolded Protein Response in Cytokine-Induced ß-Cell Death.
- Published in:
- Diabetes, 2008, v. 57, n. 1, p. 124, doi. 10.2337/db07-0944
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- Publication type:
- Article
Digenic Variants in the FGF21 Signaling Pathway Associated with Severe Insulin Resistance and Pseudoacromegaly.
- Published in:
- Journal of the Endocrine Society, 2020, v. 4, n. 12, p. 1, doi. 10.1210/jendso/bvaa138
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- Publication type:
- Article
A novel detrimental homozygous mutation in the WFS1 gene in two sisters from nonconsanguineous parents with untreated diabetes insipidus.
- Published in:
- Clinical Case Reports, 2019, v. 7, n. 12, p. 2355, doi. 10.1002/ccr3.2494
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- Publication type:
- Article
Genotype and clinical characteristics of patients with Wolfram syndrome and WFS1-related disorders.
- Published in:
- Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1198171
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- Publication type:
- Article
Mammalian ECD Protein Is a Novel Negative Regulator of the PERK Arm of the Unfolded Protein Response.
- Published in:
- Molecular & Cellular Biology, 2017, v. 37, n. 18, p. 1, doi. 10.1128/MCB.00030-17
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- Publication type:
- Article
A case of intra-abdominal desmoplastic small-round-cell tumor with elevated serum CA125.
- Published in:
- Pediatric Surgery International, 2002, v. 18, n. 4, p. 238, doi. 10.1007/s003830100696
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- Publication type:
- Article
Bisphosphonates prevent age-related weight loss in Japanese postmenopausal women.
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- Journal of Bone & Mineral Metabolism, 2018, v. 36, n. 6, p. 734, doi. 10.1007/s00774-017-0891-y
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- Publication type:
- Article
Low serum osteocalcin concentration is associated with incident type 2 diabetes mellitus in Japanese women.
- Published in:
- 2018
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- Publication type:
- journal article
Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.849204
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- Publication type:
- Article
Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis.
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- FASEB Journal, 2020, v. 34, n. 1, p. 865, doi. 10.1096/fj.201901748R
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- Publication type:
- Article
Lessons from Wolfram Syndrome: Initiation of DDAVP Therapy Causes Renal Salt Wasting Due to Elevated ANP/BNP Levels, Rescued by Fludrocortisone Treatment.
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- 2021
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- Publication type:
- journal article
Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 1, p. 1, doi. 10.1371/journal.pgen.1002457
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- Publication type:
- Article
A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response.
- Published in:
- Journal of Cell Biology, 2002, v. 158, n. 4, p. 639, doi. 10.1083/jcb.200203086
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- Publication type:
- Article
Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid.
- Published in:
- Scientific Reports, 2017, p. 41939, doi. 10.1038/srep41939
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- Publication type:
- Article
Neuroimaging evidence of deficient axon myelination in Wolfram syndrome.
- Published in:
- Scientific Reports, 2016, p. 21167, doi. 10.1038/srep21167
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- Publication type:
- Article
Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice.
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- Science Translational Medicine, 2020, v. 12, n. 540, p. 1, doi. 10.1126/scitranslmed.aax9106
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- Publication type:
- Article
10. Dantrolene as a Therapeutic Option for Wolfram Syndrome (134-OR).
- Published in:
- Nederlands Tijdschrift voor Diabetologie (NTvD), 2015, v. 13, n. 3, p. 63, doi. 10.1007/s12467-015-0031-z
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- Publication type:
- Article
The Role of ER Stress in Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome.
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- 2023
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- Publication type:
- Literature Review
The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix.
- Published in:
- EMBO Reports, 2011, v. 12, n. 5, p. 451, doi. 10.1038/embor.2011.34
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- Publication type:
- Article
Retraction: Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion.
- Published in:
- Nature Cell Biology, 2015, v. 17, n. 1, p. 105, doi. 10.1038/ncb3088
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- Publication type:
- Article
Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion.
- Published in:
- Nature Cell Biology, 2012, v. 14, n. 10, p. 1105, doi. 10.1038/ncb2578
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- Publication type:
- Article
Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5′UTR.
- Published in:
- Nucleic Acids Research, 2001, v. 29, n. 21, p. 4341, doi. 10.1093/nar/29.21.4341
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- Publication type:
- Article
Identification of unique cell type responses in pancreatic islets to stress.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49724-w
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- Publication type:
- Article
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42154-0
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- Publication type:
- Article
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
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- Human Molecular Genetics, 2016, v. 25, n. 9, p. 1803, doi. 10.1093/hmg/ddw052
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- Publication type:
- Article
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
- Published in:
- Science Signaling, 2015, v. 8, n. 382, p. 1
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- Publication type:
- Article
Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7.
- Published in:
- BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01080-7
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- Publication type:
- Article
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
- Published in:
- 2010
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- Publication type:
- journal article
corrigendum: IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA.
- Published in:
- 2002
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- Publication type:
- Erratum
Deficiency of WFS1 increases vulnerability to pathological tau in vitro and in vivo: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042085
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- Publication type:
- Article
GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.
- Published in:
- Diabetologia, 2023, v. 66, n. 7, p. 1306, doi. 10.1007/s00125-023-05905-8
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- Publication type:
- Article
Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes.
- Published in:
- Diabetologia, 2013, v. 56, n. 12, p. 2638, doi. 10.1007/s00125-013-3044-4
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- Publication type:
- Article
Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice.
- Published in:
- European Journal of Immunology, 2017, v. 47, n. 5, p. 830, doi. 10.1002/eji.201646856
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- Publication type:
- Article
KLF15 Is a Molecular Link between Endoplasmic Reticulum Stress and Insulin Resistance.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077851
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- Publication type:
- Article
c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046185
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- Publication type:
- Article
A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic β-cells.
- Published in:
- PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011812
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- Publication type:
- Article
Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009575
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- Publication type:
- Article
Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94.
- Published in:
- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004134
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- Publication type:
- Article
The Role of IRE1α in the Degradation of Insulin mRNA in Pancreatic β-Cells.
- Published in:
- PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001648
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- Publication type:
- Article
Plasma Neurofilament Light Chain Levels Are Elevated in Children and Young Adults With Wolfram Syndrome.
- Published in:
- Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.795317
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- Publication type:
- Article