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Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9.
- Published in:
- Nature, 2015, v. 520, n. 7549, p. 702, doi. 10.1038/nature14138
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- Article
Structural analysis reveals TLR7 dynamics underlying antagonism.
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- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19025-z
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- Article
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35844-2
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- Article
Structure of SARS-CoV-2 membrane protein essential for virus assembly.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32019-3
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- Article
The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function.
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- FEBS Letters, 2022, v. 596, n. 7, p. 876, doi. 10.1002/1873-3468.14302
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- Article
Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2020, v. 76, n. 8, p. 326, doi. 10.1107/S2053230X20009012
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- Article
The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 6, p. 347, doi. 10.1107/S2053230X17007336
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- Article
The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 3, p. 130, doi. 10.1107/S2053230X17001911
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- Article
Structure of human Roquin-2 and its complex with constitutive-decay element RNA.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 8, p. 1048, doi. 10.1107/S2053230X15011887
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Activation and regulation mechanisms of NOD-like receptors based on structural biology.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.953530
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- Article
Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24536-4
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- Article
Crystal twinning of human MD-2 recognizing endotoxin cores of lipopolysaccharide.
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- Journal of Synchrotron Radiation, 2008, v. 15, n. 3, p. 262, doi. 10.1107/S0909049507056531
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- Article
Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor.
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- Journal of Synchrotron Radiation, 2004, v. 11, n. 1, p. 105, doi. 10.1107/S0909049503023513
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- Article
Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains.
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- FEBS Letters, 2020, v. 594, n. 18, p. 3020, doi. 10.1002/1873-3468.13875
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- Article
Structural basis for species‐specific activation of mouse Toll‐like receptor 9.
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- FEBS Letters, 2018, v. 592, n. 15, p. 2636, doi. 10.1002/1873-3468.13176
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- Article
Toward a structural understanding of nucleic acid-sensing Toll-like receptors in the innate immune system.
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- FEBS Letters, 2017, v. 591, n. 20, p. 3167, doi. 10.1002/1873-3468.12749
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- Article
Crystal structure of NOD2 and its implications in human disease.
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- Nature Communications, 2016, v. 7, n. 6, p. 11813, doi. 10.1038/ncomms11813
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- Article
Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.
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- Nature Communications, 2015, v. 6, n. 2, p. 6119, doi. 10.1038/ncomms7119
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- Article
DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
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- Nature Communications, 2015, v. 6, n. 1, p. 5853, doi. 10.1038/ncomms6853
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- Article
Mechanisms controlling nucleic acid-sensing Toll-like receptors.
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- International Immunology, 2018, v. 30, n. 2, p. 43, doi. 10.1093/intimm/dxy016
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- Article
Guanosine and its modified derivatives are endogenous ligands for TLR7.
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- International Immunology, 2016, v. 28, n. 5, p. 211, doi. 10.1093/intimm/dxv062
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- Article
The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.
- Published in:
- International Immunology, 2014, v. 26, n. 6, p. 307, doi. 10.1093/intimm/dxt071
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- Article
Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A.
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- International Immunology, 2013, v. 25, n. 1, p. 45, doi. 10.1093/intimm/dxs084
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- Article
Structure-Based Design of Novel Human Toll-like Receptor 8 Agonists.
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- ChemMedChem, 2014, v. 9, n. 4, p. 719, doi. 10.1002/cmdc.201300573
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- Article
Propofol directly binds to and inhibits TLR7.
- Published in:
- FASEB Journal, 2022, v. 36, n. 8, p. 1, doi. 10.1096/fj.202200312R
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- Article
The effect of anesthetics on toll like receptor 9.
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- FASEB Journal, 2020, v. 34, n. 11, p. 14645, doi. 10.1096/fj.202000791RR
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Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.
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- FASEB Journal, 2019, v. 33, n. 12, p. 14528, doi. 10.1096/fj.201901570R
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- Article
Toll-like receptor 8 senses degradation products of single-stranded RNA.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 109, doi. 10.1038/nsmb.2943
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Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06452-2
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- Article
The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes.
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- PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134640
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Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
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- EMBO Journal, 2020, v. 39, n. 12, p. 1, doi. 10.15252/embj.2019101732
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- Article