Works by Umana, Pablo

Results: 41
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    Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure.

    Published in:
    Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1346502
    By:
    • Spreafico, Anna;
    • Couselo, Eva Muñoz;
    • Irmisch, Anja;
    • Bessa, Juliana;
    • Au-Yeung, George;
    • Bechter, Oliver;
    • Svane, Inge Marie;
    • Sanmamed, Miguel F.;
    • Gambardella, Valentina;
    • McKean, Meredith;
    • Callahan, Margaret;
    • Dummer, Reinhard;
    • Klein, Christian;
    • Umaña, Pablo;
    • Justies, Nicole;
    • Heil, Florian;
    • Fahrni, Linda;
    • Opolka-Hoffmann, Eugenia;
    • Waldhauer, Inja;
    • Bleul, Conrad
    Publication type:
    Article
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    Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.

    Published in:
    Science Translational Medicine, 2020, v. 12, n. 534, p. 1, doi. 10.1126/scitranslmed.aav7431
    By:
    • Mayoux, Maud;
    • Roller, Andreas;
    • Pulko, Vesna;
    • Sammicheli, Stefano;
    • Chen, Stanford;
    • Sum, Eva;
    • Jost, Christian;
    • Fransen, Marieke F.;
    • Buser, Regula B.;
    • Kowanetz, Marcin;
    • Rommel, Karolin;
    • Matos, Ines;
    • Colombetti, Sara;
    • Belousov, Anton;
    • Karanikas, Vaios;
    • Ossendorp, Ferry;
    • Hegde, Priti S.;
    • Chen, Daniel S.;
    • Umana, Pablo;
    • Perro, Mario
    Publication type:
    Article
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    XGFR*, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer.

    Published in:
    mAbs (1942-0862), 2016, v. 8, n. 4, p. 811, doi. 10.1080/19420862.2016.1160989
    By:
    • Schanzer, Juergen M.;
    • Wartha, Katharina;
    • Moessner, Ekkehard;
    • Hosse, Ralf J.;
    • Moser, Samuel;
    • Croasdale, Rebecca;
    • Trochanowska, Halina;
    • Shao, Cuiying;
    • Wang, Peng;
    • Shi, Lei;
    • Weinzierl, Tina;
    • Rieder, Natascha;
    • Bacac, Marina;
    • Ries, Carola H.;
    • Kettenberger, Hubert;
    • Schlothauer, Tilman;
    • Friess, Thomas;
    • Umana, Pablo;
    • Klein, Christian
    Publication type:
    Article
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    Response to: Monoclonal antibodies targeting CD20.

    Published in:
    mAbs (1942-0862), 2013, v. 5, n. 3, p. 337, doi. 10.4161/mabs.24108
    By:
    • Klein, Christian;
    • Lammens, Alfred;
    • Schäfer, Wolfgang;
    • Georges, Guy;
    • schwaiger, Manfred;
    • Mössner, Ekkehard;
    • Hopfner, Karl-Peter;
    • Umaña, Pablo;
    • Niederfellner, Gerhard
    Publication type:
    Article
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    Surgical planning aided with 3D technologies for management of complex paracardiac tumors.

    Published in:
    Journal of Cardiothoracic Surgery, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13019-024-03096-w
    By:
    • Pérez-Cualtán, Camilo E.;
    • Vargas-Acevedo, Catalina;
    • Sánchez-Posada, Juliana;
    • Castro-Páez, Camila;
    • Gutiérrez-Vargas, Roberto;
    • Forero-Melo, Julián F.;
    • Pérez, Juan Manuel;
    • Briceño, Juan Carlos;
    • Medina, Héctor M.;
    • Umaña, Juan Pablo;
    • Navarro-Rueda, Javier;
    • Guerrero-Chalela, Carlos Eduardo
    Publication type:
    Article
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    Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis.

    Published in:
    Journal of Nuclear Medicine, 2015, v. 56, n. 5, p. 778, doi. 10.2967/jnumed.114.152959
    By:
    • Laverman, Peter;
    • van der Geest, Tessa;
    • Terry, Samantha Y. A.;
    • Gerrits, Danny;
    • Walgreen, Birgitte;
    • Helsen, Monique M.;
    • Nayak, Tapan K.;
    • Freimoser-Grundschober, Anne;
    • Waldhauer, Inja;
    • Hosse, Ralf J.;
    • Moessner, Ekkehard;
    • Umana, Pablo;
    • Klein, Christian;
    • Oyen, Wim J. G.;
    • Koenders, Marije I.;
    • Boerman, Otto C.
    Publication type:
    Article
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    Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16838-w
    By:
    • Geiger, Martina;
    • Stubenrauch, Kay-Gunnar;
    • Sam, Johannes;
    • Richter, Wolfgang F.;
    • Jordan, Gregor;
    • Eckmann, Jan;
    • Hage, Carina;
    • Nicolini, Valeria;
    • Freimoser-Grundschober, Anne;
    • Ritter, Mirko;
    • Lauer, Matthias E.;
    • Stahlberg, Henning;
    • Ringler, Philippe;
    • Patel, Jigar;
    • Sullivan, Eric;
    • Grau-Richards, Sandra;
    • Endres, Stefan;
    • Kobold, Sebastian;
    • Umaña, Pablo;
    • Brünker, Peter
    Publication type:
    Article
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    The physiological interactome of TCR-like antibody therapeutics in human tissues.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47062-5
    By:
    • Marrer-Berger, Estelle;
    • Nicastri, Annalisa;
    • Augustin, Angelique;
    • Kramar, Vesna;
    • Liao, Hanqing;
    • Hanisch, Lydia Jasmin;
    • Carpy, Alejandro;
    • Weinzierl, Tina;
    • Durr, Evelyne;
    • Schaub, Nathalie;
    • Nudischer, Ramona;
    • Ortiz-Franyuti, Daniela;
    • Breous-Nystrom, Ekaterina;
    • Stucki, Janick;
    • Hobi, Nina;
    • Raggi, Giulia;
    • Cabon, Lauriane;
    • Lezan, Emmanuelle;
    • Umaña, Pablo;
    • Woodhouse, Isaac
    Publication type:
    Article
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    Anatomical Engineering and 3D Printing for Surgery and Medical Devices: International Review and Future Exponential Innovations.

    Published in:
    BioMed Research International, 2022, p. 1, doi. 10.1155/2022/6797745
    By:
    • Cornejo, José;
    • Cornejo-Aguilar, Jorge A.;
    • Vargas, Mariela;
    • Helguero, Carlos G.;
    • Milanezi de Andrade, Rafhael;
    • Torres-Montoya, Sebastian;
    • Asensio-Salazar, Javier;
    • Rivero Calle, Alvaro;
    • Martínez Santos, Jaime;
    • Damon, Aaron;
    • Quiñones-Hinojosa, Alfredo;
    • Quintero-Consuegra, Miguel D.;
    • Umaña, Juan Pablo;
    • Gallo-Bernal, Sebastian;
    • Briceño, Manolo;
    • Tripodi, Paolo;
    • Sebastian, Raul;
    • Perales-Villarroel, Paul;
    • De la Cruz-Ku, Gabriel;
    • Mckenzie, Travis
    Publication type:
    Article
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    Three-dimensional colon cancer organoids model the response to CEA-CD3 T-cell engagers.

    Published in:
    Theranostics, 2022, v. 12, n. 3, p. 1373, doi. 10.7150/thno.63359
    By:
    • Teijeira, Alvaro;
    • Migueliz, Itziar;
    • Garasa, Saray;
    • Karanikas, Vaios;
    • Luri, Carlos;
    • Cirella, Asunta;
    • Olivera, Irene;
    • Cañamero, Marta;
    • Alvarez, Maite;
    • Ochoa, Maria C.;
    • Rouzaut, Ana;
    • Rodriguez-Ruiz, Maria E.;
    • Sanmamed, Miguel F.;
    • Klein, Christian;
    • Umaña, Pablo;
    • Ponz, Mariano;
    • Bacac, Marina;
    • Melero, Ignacio
    Publication type:
    Article
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