Works by Turner, Nicholas J.

Results: 149

An Engineered Cholesterol Oxidase Catalyses Enantioselective Oxidation of Non‐steroidal Secondary Alcohols.

Published in:

ChemBioChem, 2022, v. 23, n. 7, p. 1, doi. 10.1002/cbic.202200075

By:

Heath, Rachel S.;
Sangster, Jack J.;
Turner, Nicholas J.

Publication type:

Article

New Trends and Future Opportunities in the Enzymatic Formation of C−C, C−N, and C−O bonds.

Published in:

ChemBioChem, 2022, v. 23, n. 6, p. 1, doi. 10.1002/cbic.202100464

By:

Sangster, Jack J.;
Marshall, James R.;
Turner, Nicholas J.;
Mangas‐Sanchez, Juan

Publication type:

Article

Direct Enzymatic Synthesis of Fatty Amines from Renewable Triglycerides and Oils.

Published in:

ChemBioChem, 2022, v. 23, n. 2, p. 1, doi. 10.1002/cbic.202100578

By:

Citoler, Joan;
Finnigan, William;
Bevinakatti, Han;
Turner, Nicholas J.

Publication type:

Article

An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols.

Published in:

ChemBioChem, 2019, v. 20, n. 2, p. 276, doi. 10.1002/cbic.201800556

By:

Heath, Rachel S.;
Birmingham, William R.;
Thompson, Matthew P.;
Taglieber, Andreas;
Daviet, Laurent;
Turner, Nicholas J.

Publication type:

Article

Characterisation of CYP102A25 from <italic>Bacillus marmarensis</italic> and CYP102A26 from <italic>Pontibacillus halophilus</italic>: P450 Homologues of BM3 with Preference towards Hydroxylation of Medium‐Chain Fatty Acids.

Published in:

ChemBioChem, 2018, v. 19, n. 5, p. 513, doi. 10.1002/cbic.201700598

By:

Porter, Joanne L.;
Manning, Jack;
Sabatini, Selina;
Tavanti, Michele;
Turner, Nicholas J.;
Flitsch, Sabine L.

Publication type:

Article

Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling.

Published in:

ChemBioChem, 2016, v. 17, n. 5, p. 426, doi. 10.1002/cbic.201500536

By:

Eichler, Anja;
Gricman, Łukasz;
Herter, Susanne;
Kelly, Paul P.;
Turner, Nicholas J.;
Pleiss, Jürgen;
Flitsch, Sabine L.

Publication type:

Article

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.

Published in:

ChemBioChem, 2015, v. 16, n. 7, p. 1052, doi. 10.1002/cbic.201402625

By:

Man, Henry;
Wells, Elizabeth;
Hussain, Shahed;
Leipold, Friedemann;
Hart, Sam;
Turkenburg, Johan P.;
Turner, Nicholas J.;
Grogan, Gideon

Publication type:

Article

Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases.

Published in:

ChemBioChem, 2014, v. 15, n. 15, p. 2201, doi. 10.1002/cbic.201402213

By:

Scheller, Philipp N.;
Fademrecht, Silvia;
Hofelzer, Sebastian;
Pleiss, Jürgen;
Leipold, Friedemann;
Turner, Nicholas J.;
Nestl, Bettina M.;
Hauer, Bernhard

Publication type:

Article

Biocatalytic Desymmetrization of an Atropisomer with both an Enantioselective Oxidase and Ketoreductases.

Published in:

Angewandte Chemie, 2010, v. 122, n. 39, p. 7164, doi. 10.1002/ange.201002580

By:

Yuan, Bo;
Page, Abigail;
Worrall, Christopher P.;
Escalettes, Franck;
Willies, Simon C.;
McDouall, Joseph J. W.;
Turner, Nicholas J.;
Clayden, Jonathan

Publication type:

Article

Highly Stereoselective Synthesis of Substituted Prolyl Peptides Using a Combination of Biocatalytic Desymmetrization and Multicomponent Reactions.

Published in:

Angewandte Chemie, 2010, v. 122, n. 31, p. 5417, doi. 10.1002/ange.201001592

By:

Znabet, Anass;
Ruijter, Eelco;
de Kanter, Frans J. J.;
Köhler, Valentin;
Helliwell, Madeleine;
Turner, Nicholas J.;
Orru, Romano V. A.

Publication type:

Article

Enantioselective Biocatalytic Oxidative Desymmetrization of Substituted Pyrrolidines.

Published in:

Angewandte Chemie, 2010, v. 122, n. 12, p. 2228, doi. 10.1002/ange.200906655

By:

Köhler, Valentin;
Bailey, Kevin R.;
Znabet, Anass;
Raftery, James;
Helliwell, Madeleine;
Turner, Nicholas J.

Publication type:

Article

Directed Evolution of an Amine Oxidase Possessing both Broad Substrate Specificity and High Enantioselectivity ( We are grateful to the BBSRC and GlaxoSmithKline for funding a postdoctoral fellowship (MA) and CASE awards (RC, AE). We also thank the Wellcome Trust for financial support. )

Published in:

Angewandte Chemie, 2003, v. 115, n. 39, p. 4955, doi. 10.1002/ange.200352100

By:

Reuben Carr;
Marina Alexeeva;
Alexis Enright;
Tom S. C. Eve;
Michael J. Dawson;
Nicholas J. Turner

Publication type:

Article

Engineered formate dehydrogenase from Chaetomium thermophilum, a promising enzymatic solution for biotechnical CO<sub>2</sub> fixation.

Published in:

Biotechnology Letters, 2020, v. 42, n. 11, p. 2251, doi. 10.1007/s10529-020-02937-7

By:

Çakar, Mehmet M.;
Ruupunen, Jouni;
Mangas-Sanchez, Juan;
Birmingham, William R.;
Yildirim, Deniz;
Turunen, Ossi;
Turner, Nicholas J.;
Valjakka, Jarkko;
Binay, Barış

Publication type:

Article

Cloning and upscale production of monoamine oxidase N (MAO-N D5) by <italic>Pichia pastoris</italic>.

Published in:

Biotechnology Letters, 2018, v. 40, n. 1, p. 127, doi. 10.1007/s10529-017-2450-y

By:

Markošová, Kristína;
Camattari, Andrea;
Rosenberg, Michal;
Glieder, Anton;
Turner, Nicholas J.;
Rebroš, Martin

Publication type:

Article

A Collaborative Journey towards the Late‐Stage Functionalization of Added‐Value Chemicals Using Engineered Halogenases.

Published in:

Helvetica Chimica Acta, 2023, v. 106, n. 1, p. 1, doi. 10.1002/hlca.202200128

By:

Büchler, Johannes;
Hegarty, Eimear;
Schroer, Kirsten;
Snajdrova, Radka;
Turner, Nicholas J.;
Loiseleur, Olivier;
Buller, Rebecca;
Le Chapelain, Camille

Publication type:

Article

One‐Step Biocatalytic Synthesis of Sustainable Surfactants by Selective Amide Bond Formation**.

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205054

By:

Lubberink, Max;
Finnigan, William;
Schnepel, Christian;
Baldwin, Christopher R.;
Turner, Nicholas J.;
Flitsch, Sabine L.

Publication type:

Article

Direct Asymmetric Reductive Amination of Alkyl (Hetero)Aryl Ketones by an Engineered Amine Dehydrogenase.

Published in:

Angewandte Chemie, 2022, v. 134, n. 21, p. 1, doi. 10.1002/ange.202202264

By:

Kong, Weixi;
Liu, Yunting;
Huang, Chen;
Zhou, Liya;
Gao, Jing;
Turner, Nicholas J.;
Jiang, Yanjun

Publication type:

Article

One‐Pot Biocatalytic In Vivo Methylation‐Hydroamination of Bioderived Lignin Monomers to Generate a Key Precursor to L‐DOPA.

Published in:

Angewandte Chemie, 2022, v. 134, n. 8, p. 1, doi. 10.1002/ange.202112855

By:

Galman, James L.;
Parmeggiani, Fabio;
Seibt, Lisa;
Birmingham, William R.;
Turner, Nicholas J.

Publication type:

Article

Synthesis of Pharmaceutically Relevant 2‐Aminotetralin and 3‐Aminochroman Derivatives via Enzymatic Reductive Amination.

Published in:

Angewandte Chemie, 2021, v. 133, n. 46, p. 24661, doi. 10.1002/ange.202110321

By:

Citoler, Joan;
Harawa, Vanessa;
Marshall, James R.;
Bevinakatti, Han;
Finnigan, James D.;
Charnock, Simon J.;
Turner, Nicholas J.

Publication type:

Article

Rücktitelbild: Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades (Angew. Chem. 34/2021).

Published in:

Angewandte Chemie, 2021, v. 133, n. 34, p. 19040, doi. 10.1002/ange.202107128

By:

Mattey, Ashley P.;
Ford, Grayson J.;
Citoler, Joan;
Baldwin, Christopher;
Marshall, James R.;
Palmer, Ryan B.;
Thompson, Matthew;
Turner, Nicholas J.;
Cosgrove, Sebastian C.;
Flitsch, Sabine L.

Publication type:

Article

Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades.

Published in:

Angewandte Chemie, 2021, v. 133, n. 34, p. 18808, doi. 10.1002/ange.202103805

By:

Mattey, Ashley P.;
Ford, Grayson J.;
Citoler, Joan;
Baldwin, Christopher;
Marshall, James R.;
Palmer, Ryan B.;
Thompson, Matthew;
Turner, Nicholas J.;
Cosgrove, Sebastian C.;
Flitsch, Sabine L.

Publication type:

Article

Titelbild: Enzymkatalysierte späte Modifizierungen: Besser spät als nie (Angew. Chem. 31/2021).

Published in:

Angewandte Chemie, 2021, v. 133, n. 31, p. 16853, doi. 10.1002/ange.202106971

By:

Romero, Elvira;
Jones, Bethan S.;
Hogg, Bethany N.;
Rué Casamajo, Arnau;
Hayes, Martin A.;
Flitsch, Sabine L.;
Turner, Nicholas J.;
Schnepel, Christian

Publication type:

Article

Enzymkatalysierte späte Modifizierungen: Besser spät als nie.

Published in:

Angewandte Chemie, 2021, v. 133, n. 31, p. 16962, doi. 10.1002/ange.202014931

By:

Romero, Elvira;
Jones, Bethan S.;
Hogg, Bethany N.;
Rué Casamajo, Arnau;
Hayes, Martin A.;
Flitsch, Sabine L.;
Turner, Nicholas J.;
Schnepel, Christian

Publication type:

Article

Asymmetric Synthesis of N‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination.

Published in:

Angewandte Chemie, 2021, v. 133, n. 16, p. 8799, doi. 10.1002/ange.202016589

By:

Yao, Peiyuan;
Marshall, James R.;
Xu, Zefei;
Lim, Jesmine;
Charnock, Simon J.;
Zhu, Dunming;
Turner, Nicholas J.

Publication type:

Article

One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 41, p. 18313, doi. 10.1002/ange.202006246

By:

Cosgrove, Sebastian C.;
Thompson, Matthew P.;
Ahmed, Syed T.;
Parmeggiani, Fabio;
Turner, Nicholas J.

Publication type:

Article

Regio‐ and Enantio‐selective Chemo‐enzymatic C−H‐Lactonization of Decanoic Acid to (S)‐δ‐Decalactone.

Published in:

Angewandte Chemie, 2019, v. 131, n. 17, p. 5724, doi. 10.1002/ange.201901242

By:

Manning, Jack;
Tavanti, Michele;
Porter, Joanne L.;
Kress, Nico;
De Visser, Sam P.;
Turner, Nicholas J.;
Flitsch, Sabine L.

Publication type:

Article

Chemo‐Enzymatic Synthesis of Pyrazines and Pyrroles.

Published in:

Angewandte Chemie, 2018, v. 130, n. 51, p. 17002, doi. 10.1002/ange.201810555

By:

Xu, Jin;
Green, Anthony P.;
Turner, Nicholas J.

Publication type:

Article

Highly Productive Oxidative Biocatalysis in Continuous Flow by Enhancing the Aqueous Equilibrium Solubility of Oxygen.

Published in:

Angewandte Chemie, 2018, v. 130, n. 33, p. 10695, doi. 10.1002/ange.201803675

By:

Chapman, Michael R.;
Cosgrove, Sebastian C.;
Turner, Nicholas J.;
Kapur, Nikil;
Blacker, A. John

Publication type:

Article

Algorithm-aided engineering of aliphatic halogenase WelO5* for the asymmetric late-stage functionalization of soraphens.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27999-1

By:

Büchler, Johannes;
Malca, Sumire Honda;
Patsch, David;
Voss, Moritz;
Turner, Nicholas J.;
Bornscheuer, Uwe T.;
Allemann, Oliver;
Le Chapelain, Camille;
Lumbroso, Alexandre;
Loiseleur, Olivier;
Buller, Rebecca

Publication type:

Article

Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25034-3

By:

Birmingham, William R.;
Toftgaard Pedersen, Asbjørn;
Dias Gomes, Mafalda;
Bøje Madsen, Mathias;
Breuer, Michael;
Woodley, John M.;
Turner, Nicholas J.

Publication type:

Article

Stereoselective Synthesis of Aliphatic α‐Amino Acids by Chemo‐Enzymatic Hydroamination‐Hydrodesulfurisation.

Published in:

Advanced Synthesis & Catalysis, 2025, v. 367, n. 4, p. 1, doi. 10.1002/adsc.202401223

By:

Nobbio, Celeste;
Birmingham, William R.;
Brenna, Elisabetta;
Turner, Nicholas J.;
Tessaro, Davide;
Parmeggiani, Fabio

Publication type:

Article

Biocatalysis: Ready to Master Increasing Complexity.

Published in:

Advanced Synthesis & Catalysis, 2019, v. 361, n. 11, p. 2373, doi. 10.1002/adsc.201900610

By:

Faber, Kurt;
Fessner, Wolf‐Dieter;
Turner, Nicholas J.

Publication type:

Article

Data‐driven enzyme immobilisation: a case study using DNA to immobilise galactose oxidase.

Published in:

Engineering Biology, 2020, v. 4, p. 43, doi. 10.1049/enb.2020.0014

By:

Ott, Wolfgang;
Ceccarelli, Alessandro;
Manning, Jack;
Turner, Nicholas J.;
Oppenheimer, Robert

Publication type:

Article

Directed Evolution of the Enzyme Monoamine Oxidase (MAO-N): Highly Efficient Chemo-enzymatic Deracemisation of the Alkaloid (±)-Crispine A.

Published in:

ChemCatChem, 2012, v. 4, n. 9, p. 1259, doi. 10.1002/cctc.201200202

By:

Rowles, Ian;
Malone, Kirk J.;
Etchells, Laura L.;
Willies, Simon C.;
Turner, Nicholas J.

Publication type:

Article

Biosynthesis and Characterization of Copper Nanoparticles Using <italic>Shewanella oneidensis</italic>: Application for Click Chemistry.

Published in:

Small, 2018, v. 14, n. 10, p. 1, doi. 10.1002/smll.201703145

By:

Kimber, Richard L.;
Lewis, Edward A.;
Parmeggiani, Fabio;
Smith, Kurt;
Bagshaw, Heath;
Starborg, Toby;
Joshi, Nimisha;
Figueroa, Adriana I.;
van der Laan, Gerrit;
Cibin, Giannantonio;
Gianolio, Diego;
Haigh, Sarah J.;
Pattrick, Richard A. D.;
Turner, Nicholas J.;
Lloyd, Jonathan R.

Publication type:

Article

Biotechnological synthesis of Pd/Ag and Pd/Au nanoparticles for enhanced Suzuki–Miyaura cross‐coupling activity.

Published in:

Microbial Biotechnology, 2021, v. 14, n. 6, p. 2435, doi. 10.1111/1751-7915.13762

By:

Kimber, Richard L.;
Parmeggiani, Fabio;
Neill, Thomas S.;
Merroun, Mohamed L.;
Goodlet, Gregory;
Powell, Nigel A.;
Turner, Nicholas J.;
Lloyd, Jonathan R.

Publication type:

Article

Biocatalytic Desymmetrization of an Atropisomer with both an Enantioselective Oxidase and Ketoreductases.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 39, p. 7010, doi. 10.1002/anie.201002580

By:

Yuan, Bo;
Page, Abigail;
Worrall, Christopher P.;
Escalettes, Franck;
Willies, Simon C.;
McDouall, Joseph J. W.;
Turner, Nicholas J.;
Clayden, Jonathan

Publication type:

Article

Highly Stereoselective Synthesis of Substituted Prolyl Peptides Using a Combination of Biocatalytic Desymmetrization and Multicomponent Reactions.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 31, p. 5289, doi. 10.1002/anie.201001592

By:

Znabet, Anass;
Ruijter, Eelco;
de Kanter, Frans J. J.;
Köhler, Valentin;
Helliwell, Madeleine;
Turner, Nicholas J.;
Orru, Romano V. A.

Publication type:

Article

Enantioselective Biocatalytic Oxidative Desymmetrization of Substituted Pyrrolidines.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 12, p. 2182, doi. 10.1002/anie.200906655

By:

Köhler, Valentin;
Bailey, Kevin R.;
Znabet, Anass;
Raftery, James;
Helliwell, Madeleine;
Turner, Nicholas J.

Publication type:

Article

Rapid Determination of Both the Activity and Enantioselectivity of Ketoreductases.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 14, p. 2639, doi. 10.1002/anie.200705046

By:

Truppo, Matthew D.;
Escalettes, Franck;
Turner, Nicholas J.

Publication type:

Article

Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0184183

By:

Hartley, Carol J.;
French, Nigel G.;
Scoble, Judith A.;
Williams, Charlotte C.;
Churches, Quentin I.;
Frazer, Andrew R.;
Taylor, Matthew C.;
Coia, Greg;
Simpson, Gregory;
Turner, Nicholas J.;
Scott, Colin

Publication type:

Article

The Impact of Metagenomics on Biocatalysis.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 21, p. 1, doi. 10.1002/anie.202402316

By:

Hogg, Bethany N.;
Schnepel, Christian;
Finnigan, James D.;
Charnock, Simon J.;
Hayes, Martin A.;
Turner, Nicholas J.

Publication type:

Article

One‐Step Biocatalytic Synthesis of Sustainable Surfactants by Selective Amide Bond Formation**.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 30, p. 1, doi. 10.1002/anie.202205054

By:

Lubberink, Max;
Finnigan, William;
Schnepel, Christian;
Baldwin, Christopher R.;
Turner, Nicholas J.;
Flitsch, Sabine L.

Publication type:

Article

Direct Asymmetric Reductive Amination of Alkyl (Hetero)Aryl Ketones by an Engineered Amine Dehydrogenase.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 21, p. 1, doi. 10.1002/anie.202202264

By:

Kong, Weixi;
Liu, Yunting;
Huang, Chen;
Zhou, Liya;
Gao, Jing;
Turner, Nicholas J.;
Jiang, Yanjun

Publication type:

Article

One‐Pot Biocatalytic In Vivo Methylation‐Hydroamination of Bioderived Lignin Monomers to Generate a Key Precursor to L‐DOPA.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 8, p. 1, doi. 10.1002/anie.202112855

By:

Galman, James L.;
Parmeggiani, Fabio;
Seibt, Lisa;
Birmingham, William R.;
Turner, Nicholas J.

Publication type:

Article

Synthesis of Pharmaceutically Relevant 2‐Aminotetralin and 3‐Aminochroman Derivatives via Enzymatic Reductive Amination.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 46, p. 24456, doi. 10.1002/anie.202110321

By:

Citoler, Joan;
Harawa, Vanessa;
Marshall, James R.;
Bevinakatti, Han;
Finnigan, James D.;
Charnock, Simon J.;
Turner, Nicholas J.

Publication type:

Article

Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 34, p. 18660, doi. 10.1002/anie.202103805

By:

Mattey, Ashley P.;
Ford, Grayson J.;
Citoler, Joan;
Baldwin, Christopher;
Marshall, James R.;
Palmer, Ryan B.;
Thompson, Matthew;
Turner, Nicholas J.;
Cosgrove, Sebastian C.;
Flitsch, Sabine L.

Publication type:

Article

Back Cover: Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades (Angew. Chem. Int. Ed. 34/2021).

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 34, p. 18892, doi. 10.1002/anie.202107128

By:

Mattey, Ashley P.;
Ford, Grayson J.;
Citoler, Joan;
Baldwin, Christopher;
Marshall, James R.;
Palmer, Ryan B.;
Thompson, Matthew;
Turner, Nicholas J.;
Cosgrove, Sebastian C.;
Flitsch, Sabine L.

Publication type:

Article

Cover Picture: Enzymatic Late‐Stage Modifications: Better Late Than Never (Angew. Chem. Int. Ed. 31/2021).

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 16717, doi. 10.1002/anie.202106971

By:

Romero, Elvira;
Jones, Bethan S.;
Hogg, Bethany N.;
Rué Casamajo, Arnau;
Hayes, Martin A.;
Flitsch, Sabine L.;
Turner, Nicholas J.;
Schnepel, Christian

Publication type:

Article

Enzymatic Late‐Stage Modifications: Better Late Than Never.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 16824, doi. 10.1002/anie.202014931

By:

Romero, Elvira;
Jones, Bethan S.;
Hogg, Bethany N.;
Rué Casamajo, Arnau;
Hayes, Martin A.;
Flitsch, Sabine L.;
Turner, Nicholas J.;
Schnepel, Christian

Publication type:

Article