Works by Turkson, James

Results: 30

Artificially Induced Protein-Membrane Anchorage with Cholesterol-Based Recognition Agents as a New Therapeutic Concept.

Published in:

Angewandte Chemie, 2011, v. 123, n. 28, p. 6372, doi. 10.1002/ange.201102486

By:

Avadisian, Miriam;
Fletcher, Steven;
Liu, Baoxu;
Zhao, Wei;
Yue, Peibin;
Badali, Daniel;
Xu, Wei;
Schimmer, Aaron D.;
Turkson, James;
Gradinaru, Claudiu C.;
Gunning, Patrick T.

Publication type:

Article

Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo.

Published in:

Cell Death & Disease, 2022, v. 13, n. 12, p. 1, doi. 10.1038/s41419-022-05477-2

By:

Zhu, Yinsong;
Yue, Peibin;
Dickinson, Cody F.;
Yang, Justin K.;
Datanagan, Kyrstin;
Zhai, Ning;
Zhang, Yi;
Miklossy, Gabriella;
Lopez-Tapia, Francisco;
Tius, Marcus A.;
Turkson, James

Publication type:

Article

A Functional Nuclear Epidermal Growth Factor Receptor, Src and Stat3 Heteromeric Complex in Pancreatic Cancer Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019605

By:

Jaganathan, Soumya;
Peibin Yue;
Paladino, David C.;
Bogdanovic, Jelena;
Qun Huo;
Turkson, James

Publication type:

Article

Therapeutic modulators of STAT signalling for human diseases.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 8, p. 611, doi. 10.1038/nrd4088

By:

Miklossy, Gabriella;
Hilliard, Tyvette S.;
Turkson, James

Publication type:

Article

Targeting Protein-Protein Interactions: Suppression of Stat3 Dimerization with Rationally Designed Small-Molecule, Nonpeptidic SH2 Domain Binders.

Published in:

ChemBioChem, 2008, v. 9, n. 17, p. 2800, doi. 10.1002/cbic.200800291

By:

Gunning, Patrick T.;
Glenn, Matthew P.;
Siddiquee, Khandaker A. Z.;
Katt, William P.;
Masson, Eric;
Sebti, Saïd M.;
Turkson, James;
Hamilton, Andrew D.

Publication type:

Article

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.

Published in:

Oncogene, 2002, v. 21, n. 13, p. 2000, doi. 10.1038/sj.onc.1205260

By:

Niu, Guilian;
Wright, Kenneth L.;
Huang, Mei;
Song, Lanxi;
Haura, Eric;
Turkson, James;
Shumin Zhang;
Wang, Tianhong;
Sinibaldi, Dominic;
Coppola, Domenico;
Heller, Richard;
Ellis, Lee M.;
Karras, James;
Bromberg, Jacqueline;
Pardoll, Drew;
Jove, Richard;
Hua Yu

Publication type:

Article

STAT proteins: novel molecular targets for cancer drug discovery.

Published in:

Oncogene, 2000, v. 19, n. 56, p. 6613, doi. 10.1038/sj.onc.1204086

By:

Turkson, James;
Jove, Richard

Publication type:

Article

Induction of p21<sup>WAF1/CIP1</sup> and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling.

Published in:

Oncogene, 2000, v. 19, n. 48, p. 5419, doi. 10.1038/sj.onc.1203947

By:

Sinibaldi, Dominic;
Wharton, Walker;
Turkson, James;
Bowman, Tammy;
Pledger, Warren J;
Jove, Richard

Publication type:

Article

STATs in oncogenesis.

Published in:

Oncogene, 2000, v. 19, n. 21, p. 2474, doi. 10.1038/sj.onc.1203527

By:

Bowman, Tammy;
Garcia, Roy;
Turkson, James;
Jove, Richard

Publication type:

Article

Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols.

Published in:

EMBO Journal, 2002, v. 21, n. 13, p. 3486, doi. 10.1093/emboj/cdf350

By:

Bild, Andrea H.;
Turkson, James;
Jove, Richard

Publication type:

Article

Cytoplasmic transport of Stat3 by receptor-mediated endocytosis.

Published in:

EMBO Journal, 2002, v. 21, n. 13, p. 3255, doi. 10.1093/emboj/cdf351

By:

Bild, Andrea H.;
Turkson, James;
Jove, Richard

Publication type:

Article

An Unusual Benzoisoquinoline-9-one Derivative and Other Related Compounds with Antiproliferative Activity from Hawaiian Endophytic Fungus Peyronellaea sp. FT431.

Published in:

Molecules, 2019, v. 24, n. 1, p. 196, doi. 10.3390/molecules24010196

By:

Li, Chunshun;
Sarotti, Ariel M.;
Wu, Xiaohua;
Yang, Baojun;
Turkson, James;
Chen, Yongfei;
Liu, Qingsong;
Cao, Shugeng

Publication type:

Article

Buffer-Stable Chitosan-Polyglutamic Acid Hybrid Nanoparticles for Biomedical Applications.

Published in:

Macromolecular Bioscience, 2013, v. 13, n. 5, p. 603, doi. 10.1002/mabi.201200425

By:

Malhotra, Astha;
Zhang, Xiaolei;
Turkson, James;
Santra, Swadeshmukul

Publication type:

Article

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways.

Published in:

Oncogene, 2005, v. 24, n. 36, p. 5552, doi. 10.1038/sj.onc.1208719

By:

Qing Xu;
Briggs, Jon;
Sungman Park;
Niu, Guilian;
Kortylewski, Marcin;
Shumin Zhang;
Gritsko, Tanya;
Turkson, James;
Kay, Heidi;
Semenza, Gregg L.;
Cheng, Jin Q.;
Jove, Richard;
Yu, Hua

Publication type:

Article

Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells.

Published in:

Oncogene, 2004, v. 23, n. 15, p. 2600, doi. 10.1038/sj.onc.1207378

By:

Vultur, Adina;
Cao, Jun;
Arulanandam, Rozanne;
Turkson, James;
Jove, Richard;
Greer, Peter;
Craig, Andrew;
Elliott, Bruce;
Raptis, Leda

Publication type:

Article

Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells.

Published in:

Oncogene, 2003, v. 22, n. 27, p. 4150, doi. 10.1038/sj.onc.1206479

By:

Song, Lanxi;
Turkson, James;
Karras, James G;
Jove, Richard;
Haura, Eric B

Publication type:

Article

Small Molecule Induces Time‐Dependent Inhibition of Stat3 Dimerization and DNA‐Binding Activity and Regresses Human Breast Tumor Xenografts.

Published in:

ChemBioChem, 2024, v. 25, n. 22, p. 1, doi. 10.1002/cbic.202400351

By:

Yue, Peibin;
Chen, Yue;
Ogese, Monday O.;
Sun, Shan;
Zhang, Xiaolei;
Esan, Taiwo;
Buolamwini, John K.;
Turkson, James

Publication type:

Article

A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062.

Published in:

Molecules, 2017, v. 22, n. 7, p. 1166, doi. 10.3390/molecules22071166

By:

Chunshun Li;
Sarotti, Ariel M.;
Baojun Yang;
Turkson, James;
Shugeng Cao

Publication type:

Article

Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge Dactylospongia elegans.

Published in:

Marine Drugs, 2019, v. 17, n. 8, p. 423, doi. 10.3390/md17070423

By:

Neupane, Ram P.;
Parrish, Stephen M.;
Bhandari Neupane, Jayanti;
Yoshida, Wesley Y.;
Yip, M. L. Richard;
Turkson, James;
Harper, Mary Kay;
Head, John D.;
Williams, Philip G.

Publication type:

Article

Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge Dactylospongia elegans.

Published in:

Marine Drugs, 2019, v. 17, n. 7, p. 423, doi. 10.3390/md17070423

By:

Neupane, Ram P.;
Parrish, Stephen M.;
Bhandari Neupane, Jayanti;
Yoshida, Wesley Y.;
Yip, M. L. Richard;
Turkson, James;
Harper, Mary Kay;
Head, John D.;
Williams, Philip G.

Publication type:

Article

Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities.

Published in:

ChemBioChem, 2009, v. 10, n. 12, p. 1959, doi. 10.1002/cbic.200900172

By:

Fletcher, Steven;
Singh, Jardeep;
Zhang, Xiaolei;
Yue, Peibin;
Page, Brent D. G.;
Sharmeen, Sumaiya;
Shahani, Vijay M.;
Zhao, Wei;
Schimmer, Aaron D.;
Turkson, James;
Gunning, Patrick T.

Publication type:

Article

Inside Cover: Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities (ChemBioChem 12/2009).

Published in:

ChemBioChem, 2009, v. 10, n. 12, p. 1906, doi. 10.1002/cbic.200990048

By:

Fletcher, Steven;
Singh, Jardeephi;
Zhang, Xiaolei;
Yue, Peibin;
Page, Brent D. G.;
Sharmeen, Sumaiya;
Shahani, Vijay M.;
Zhao, Wei;
Schimmer, Aaron D.;
Turkson, James;
Gunning, Patrick T.

Publication type:

Article

Stat3 controls lysosomal-mediated cell death in vivo.

Published in:

Nature Cell Biology, 2011, v. 13, n. 3, p. 303, doi. 10.1038/ncb2171

By:

Kreuzaler, Peter A.;
Staniszewska, Anna D.;
Li, Wenjing;
Omidvar, Nader;
Kedjouar, Blandine;
Turkson, James;
Poli, Valeria;
Flavell, Richard A.;
Clarkson, Richard W. E.;
Watson, Christine J.

Publication type:

Article

STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)–STAT3 pathway.

Published in:

Leukemia & Lymphoma, 2016, v. 57, n. 11, p. 2681, doi. 10.3109/10428194.2016.1153089

By:

Belton, Amy;
Xian, Lingling;
Huso, Tait;
Koo, Michael;
Luo, Li Z.;
Turkson, James;
Page, Brent D. G.;
Gunning, Patrick T.;
Liu, Guosheng;
Huso, David L.;
Resar, Linda M. S.

Publication type:

Article

Nanoparticle delivery of inhibitory signal transducer and activator of transcription 3 G-quartet oligonucleotides blocks tumor growth in HMGA1 transgenic model of T-cell leukemia.

Published in:

Leukemia & Lymphoma, 2014, v. 55, n. 5, p. 1194, doi. 10.3109/10428194.2013.821202

By:

Hillion, Joelle;
Belton, Amy M.;
Shah, Sandeep N.;
Turkson, James;
Jing, Naijie;
Tweardy, David J.;
di Cello, Francescopaolo;
Huso, David L.;
Resar, Linda M. S.

Publication type:

Article

Antagonism of the Stat3-Stat3 Protein Dimer with Salicylic Acid Based Small Molecules.

Published in:

ChemMedChem, 2011, v. 6, n. 8, p. 1459, doi. 10.1002/cmdc.201100194

By:

Fletcher, Steven;
Page, Brent D. G.;
Zhang, Xialoei;
Yue, Peibin;
Li, Zhi Hua;
Sharmeen, Sumaiya;
Singh, Jagdeep;
Zhao, Wei;
Schimmer, Aaron D.;
Trudel, Suzanne;
Turkson, James;
Gunning, Patrick T.

Publication type:

Article

Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein.

Published in:

ChemMedChem, 2008, v. 3, n. 8, p. 1159, doi. 10.1002/cmdc.200800123

By:

Fletcher, Steven;
Turkson, James;
Gunning, Patrick T.

Publication type:

Article

Cover Picture: Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein (ChemMedChem 8/2008).

Published in:

ChemMedChem, 2008, v. 3, n. 8, p. 1145, doi. 10.1002/cmdc.200890030

By:

Fletcher, Steven;
Turkson, James;
Gunning, Patrick T.

Publication type:

Article

Artificially Induced Protein-Membrane Anchorage with Cholesterol-Based Recognition Agents as a New Therapeutic Concept.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 28, p. 6248, doi. 10.1002/anie.201102486

By:

Avadisian, Miriam;
Fletcher, Steven;
Liu, Baoxu;
Zhao, Wei;
Yue, Peibin;
Badali, Daniel;
Xu, Wei;
Schimmer, Aaron D.;
Turkson, James;
Gradinaru, Claudiu C.;
Gunning, Patrick T.

Publication type:

Article

STAT3 as a target for inducing apoptosis in solid and hematological tumors.

Published in:

Cell Research, 2008, v. 18, n. 2, p. 254, doi. 10.1038/cr.2008.18

By:

Al Zaid Siddiquee, Khandaker;
Turkson, James

Publication type:

Article