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Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes.
Published in:
2005
By:
- Smyth, Deborah J.;
- Howson, Joanna M. M.;
- Lowe, Christopher E.;
- Walker, Neil M.;
- Lam, Alex C.;
- Nutland, Sarah;
- Hutchings, Jayne;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Guja, Cristian;
- Ionescu-Tirgoviste, Constantin;
- Undlien, Dag E.;
- Rønningen, Kjersti S.;
- Savage, David;
- Dunger, David B.;
- Twells, Rebecca C. J.;
- McArdle, Wendy L.;
- Strachan, David P.;
- Todd, John A.
Publication type:
Letter
Parameters for reliable results in genetic association studies in common disease.
Published in:
Nature Genetics, 2002, v. 30, n. 2, p. 149, doi. 10.1038/ng825
By:
- Dahlman, Ingrid;
- Eaves, Iain A.;
- Kosoy, Roman;
- Morrison, V. Anne;
- Heward, Joanne;
- Gough, Stephen C.L.;
- Allahabadia, Amit;
- Franklyn, Jayne A.;
- Tuomilehto, Jaakko;
- Tuomilehto-Wolf, Eva;
- Cucca, Francesco;
- Guja, Cristian;
- Ionescu-Tirgoviste, Constantin;
- Stevens, Helen;
- Carr, Philippa;
- Nutland, Sarah;
- McKinney, Patricia;
- Shield, Julian P.;
- Wang, William
Publication type:
Article
Haplotype tagging for the identification of common disease genes.
Published in:
Nature Genetics, 2001, v. 29, n. 2, p. 233, doi. 10.1038/ng1001-233
By:
- Johnson, Gillian C.L.;
- Esposito, Laura;
- Barratt, Bryan J.;
- Smith, Annabel N.;
- Heward, Joanne;
- Di Genova, Gianfranco;
- Ueda, Hironori;
- Cordell, Heather J.;
- Eaves, Iain A.;
- Dudbridge, Frank;
- Twells, Rebecca C.J.;
- Payne, Felicity;
- Hughes, Wil;
- Nutland, Sarah;
- Stevens, Helen;
- Carr, Phillipa;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Gough, Stephen C.L.
Publication type:
Article
The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes.
Published in:
Nature Genetics, 2000, v. 25, n. 3, p. 320, doi. 10.1038/77091
By:
- Eaves, Iain A.;
- Merriman, Tony R.;
- Barber, Rachael A.;
- Nutland, Sarah;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Cucca, Francesco;
- Todd, John A.
Publication type:
Article
Full Likelihood Analysis of Genetic Risk with Variable Age at Onset Disease -- Combining Population-Based Registry Data and Demographic Information.
Published in:
PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006836
By:
- Pitkäniemi, Janne;
- Varvio, Sirkka-Liisa;
- Corander, Jukka;
- Lehti, Nella;
- Partanen, Jukka;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Thomas, Andrew;
- Arjas, Elja
Publication type:
Article
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes.
Published in:
Human Genetics, 2003, v. 113, n. 2, p. 99, doi. 10.1007/s00439-003-0940-6
By:
- Twells, Rebecca C. J.;
- Mein, Charles A.;
- Payne, Felicity;
- Veijola, Riitta;
- Gilbey, Matthew;
- Bright, Matthew;
- Timms, Andrew;
- Nakagawa, Yusuke;
- Snook, Hywel;
- Nutland, Sarah;
- Rance, Helen E.;
- Carr, Philippa;
- Dudbridge, Frank;
- Cordell, Heather J.;
- Cooper, Jason;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Phillips, Michael;
- Metzker, Michael;
- Hess, J. Fred
Publication type:
Article
Neonatal Anthropometric Measurements and Risk of Childhood-Onset Type 1 Diabetes.
Published in:
Diabetes Care, 1999, v. 22, n. 12, p. 2092, doi. 10.2337/diacare.22.12.2092a
By:
- Podar, Toomas;
- Onkamo, Paivi;
- Forsen, Tom;
- Karvonen, Marjatta;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko
Publication type:
Article
Mapping Genes for NIDDM.
Published in:
Diabetes Care, 1998, v. 21, n. 6, p. 949, doi. 10.2337/diacare.21.6.949
By:
- Valle, Timo;
- Tuomilehto, Jaakko;
- Bergman, Richard N.;
- Ghosh, Soumitra;
- Hauser, Elizabeth R.;
- Eriksson, Johan;
- Nylund, Stella J.;
- Kohtamäki, Kimmo;
- Toivanen, Liisa;
- Vidgren, Gabriele;
- Tuomilehto-Wolf, Eva;
- Ehnholm, Christian;
- Blaschak, Jillian;
- Langefeld, Carl D.;
- Watanabe, Richard M.;
- Magnuson, Victoria;
- Ally, Delphine S.;
- Hagopian, William A.;
- Ross, Edna;
- Buchanan, Thomas A.
Publication type:
Article
Comparison of incidence of IDDM in childhood between Estonia and Finland, 1980-1988.
Published in:
1991
By:
- Tuomilehto, Jaakko;
- Podar, Toomas;
- Reunanen, Antti;
- Kalits, Irina;
- Lounamaa, Raisa;
- Tuomilehto-Wolf, Eva;
- Adojaan, Bela;
- Neff, Barbara;
- LaPorte, Ronald E.;
- Tuomilehto, J;
- Podar, T;
- Reunanen, A;
- Kalits, I;
- Lounamaa, R;
- Tuomilehto-Wolf, E;
- Adojaan, B;
- Neff, B;
- LaPorte, R E
Publication type:
journal article
A genome-wide scan for type 1 diabetes susceptibility genes innuclear families with multiple affected siblings in Finland.
Published in:
BMC Genetics, 2007, v. 8, p. 84, doi. 10.1186/1471-2156-8-84
By:
- Qing Qiao;
- Österholm, Anne-May;
- Bing He;
- Pitkäniemi, Janne;
- Cordell, Heather J.;
- Sarti, Cinzia;
- Kinnunen, Leena;
- Tuomilehto-Wolf, Eva;
- Tryggvason, Karl;
- Tuomilehto, Jaakko
Publication type:
Article
Seasonality in the Clinical Onset of Insulin-dependent Diabetes Mellitus in Finnish Children.
Published in:
American Journal of Epidemiology, 1996, v. 143, n. 2, p. 167, doi. 10.1093/oxfordjournals.aje.a008726
By:
- Karvonen, Marjatta;
- Tuomilehto, Jaakko;
- Virtala, Esa;
- Pitkäniemi, Janne;
- Reunanen, Antti;
- Tuomilehto-Wolf, Eva;
- Åkerblom, Hans K.
Publication type:
Article
Insulin-dependent Diabetes Mellitus in Native Estonians and Immigrants to Estonia.
Published in:
American Journal of Epidemiology, 1992, v. 135, n. 11, p. 1231, doi. 10.1093/oxfordjournals.aje.a116229
By:
- Podar, Toomas;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- LaPorte, Ronald E.;
- Adojaan, Bela
Publication type:
Article
Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.
Published in:
2004
By:
- Nejentsev, Sergey;
- Cooper, Jason D.;
- Godfrey, Lisa;
- Howson, Joanna M. M.;
- Rance, Helen;
- Nutland, Sarah;
- Walker, Neil M.;
- Guja, Cristian;
- Ionescu-Tirgoviste, Constantin;
- Savage, David A.;
- Undlien, Dag E.;
- Rønningen, Kjersti S.;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Gillespie, Kathleen M.;
- Ring, Susan M.;
- Strachan, David P.;
- Widmer, Barry;
- Dunger, David;
- Todd, John A.
Publication type:
journal article
Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes.
Published in:
2004
By:
- Hulme, John S.;
- Barratt, Bryan J.;
- Twells, Rebecca C.J.;
- Cooper, Jason D.;
- Lowe, Chris E.;
- Howson, Joanna M.M.;
- Lam, Alex C.;
- Smink, Luc J.;
- Savage, David A.;
- Undlien, Dag E.;
- Guja, Cristian;
- Ionescu-Tîrgoviste, Constantin;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Todd, John A.;
- Ionescu-Tîirgoviste, Constantin
Publication type:
journal article
Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes.
Published in:
2004
By:
- Vella, Adrian;
- Howson, Joanna M. M.;
- Barratt, Bryan J.;
- Twells, Rebecca C. J.;
- Rance, Helen E.;
- Nutland, Sarah;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Undlien, Dag E.;
- Rønningen, Kjersti S.;
- Guja, Cristian;
- Ionescu-Tîrgoviste, Constantin;
- Savage, David A.;
- Todd, John A.;
- Rønningen, Kjersti S;
- Ionescu-Tîrgovişte, Constantin
Publication type:
journal article
Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes.
Published in:
2004
By:
- Eftychi, Christina;
- Howson, Joanna M. M.;
- Barratt, Bryan J.;
- Vella, Adrian;
- Payne, Felicity;
- Smyth, Deborah J.;
- Twells, Rebecca C. J.;
- Walker, Neil M.;
- Rance, Helen E.;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Undlien, Dag E.;
- Rønningen, Kjersti S.;
- Guja, Cristian;
- Ionescu-Tîrgoviste, Constantin;
- Savage, David A.;
- Todd, John A.;
- Rønningen, Kjersti S;
- Ionescu-Tîirgovişte, Constantin
Publication type:
journal article
A comprehensive, statistically powered analysis of GAD2 in type 1 diabetes.
Published in:
2002
By:
- Johnson, Gillian C.L.;
- Payne, Felicity;
- Nutland, Sarah;
- Stevens, Helen;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Todd, John A.
Publication type:
journal article
Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases.
Published in:
2001
By:
- Merriman, Tony R.;
- Cordell, Heather J.;
- Eaves, Iain A.;
- Danoy, Patrick A.;
- Coraddu, Francesca;
- Barber, Rachael;
- Cucca, Francesco;
- Broadley, Simon;
- Sawcer, Stephen;
- Compston, Alastair;
- Wordsworth, Paul;
- Shatford, Jane;
- Laval, Steve;
- Jirholt, Johan;
- Holmdahl, Rikard;
- Theofilopoulos, Argyrios N.;
- Kono, Dwight H.;
- Tuomilehto, Jaakko;
- Tuomilehto-Wolf, Eva;
- Buzzetti, Raffaella
Publication type:
journal article
Genetic markers, humoral autoimmunity, and prediction of type 1 diabetes in siblings of affected children. Childhood Diabetes in Finland Study Group.
Published in:
2000
By:
- Kulmala, Petri;
- Savola, Kaisa;
- Reijonen, Helena;
- Veijola, Riitta;
- Vahasalo, Paula;
- Karjalainen, Jukka;
- Tuomilehto-Wolf, Eva;
- Ilonen, Jorma;
- Tuomilehto, Jaakko;
- Akerblom, Hans K.;
- Knip, Mikael;
- Kulmala, P;
- Savola, K;
- Reijonen, H;
- Veijola, R;
- Vähäsalo, P;
- Karjalainen, J;
- Tuomilehto-Wolf, E;
- Ilonen, J;
- Tuomilehto, J
Publication type:
journal article
Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group.
Published in:
1998
By:
- Esposito, Laura;
- Hill, Natasha J.;
- Pritchard, Lynn E.;
- Cucca, Francesco;
- Muxworthy, Claire;
- Merriman, Marilyn E.;
- Wilson, Amanda;
- Julier, Cecile;
- Delepine, Marc;
- Tuomilehto, Jaakko;
- Tuomilehto-Wolf, Eva;
- Ionesco-Tirgoviste, Constantin;
- Nistico, Lorenza;
- Buzzetti, Raffaella;
- Pozzilli, Paolo;
- Ferrari, Maurizio;
- Bosi, Emanuele;
- Pociot, Flemming;
- Nerup, Jorn;
- Bain, Stephan C.
Publication type:
journal article
Human leukocyte antigen identity and DQ risk alleles in autoantibody-positive siblings of children with IDDM are associated with reduced early insulin response. Childhood Diabetes in Finland (DiMe) Study Group.
Published in:
1995
By:
- Veijola, Riitta;
- Vähäsalo, Paula;
- Tuomilehto-Wolf, Eva;
- Reijonen, Helena;
- Kulmala, Petri;
- Ilonen, Jorma;
- Åkerblom, Hans K.;
- Knip, Mikael;
- Veijola, R;
- Vähäsalo, P;
- Tuomilehto-Wolf, E;
- Reijonen, H;
- Kulmala, P;
- Ilonen, J;
- Akerblom, H K;
- Knip, M
Publication type:
journal article
Chromosome 4q locus associated with insulin resistance in Pima Indians. Studies in three European NIDDM populations.
Published in:
1994
By:
- Humphreys, Phillippa;
- McCarthy, Mark;
- Tuomilehto, Jaakko;
- Tuomilehto-Wolf, Eva;
- Stratton, Irene;
- Morgan, Ruth;
- Rees, Alan;
- Owens, David;
- Stengård, Jari;
- Nissinen, Aulikki;
- Hitman, Graham;
- Turner, Robert C.;
- O'Rahilly, Stephen;
- Humphreys, P;
- McCarthy, M;
- Tuomilehto, J;
- Tuomilehto-Wolf, E;
- Stratton, I;
- Morgan, R;
- Rees, A
Publication type:
journal article
Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene.
Published in:
Human Molecular Genetics, 2004, v. 13, n. 15, p. 1633, doi. 10.1093/hmg/ddh169
By:
- Nejentsev, Sergey;
- Godfrey, Lisa;
- Snook, Hywel;
- Rance, Helen;
- Nutland, Sarah;
- Walker, Neil M.;
- Lam, Alex C.;
- Guja, Cristian;
- Ionescu-Tirgoviste, Constantin;
- Undlien, Dag E.;
- Rønningen, Kjersti S.;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko;
- Newport, Melanie J.;
- Clayton, David G.;
- Todd, John A.
Publication type:
Article
Variation in HLA-associated risks of childhood insulin-dependent diabetes in the finnish population: II. Haplotype effects.
Published in:
Genetic Epidemiology, 1995, v. 12, n. 5, p. 455, doi. 10.1002/gepi.1370120503
By:
- Thomas, Duncan;
- Pitkäniemi, Janne;
- Langholz, Bryan;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko
Publication type:
Article
Class I and II HLA Genes Are Associated with Susceptibility and Age at Onset in Finnish Families with Type 1 Diabetes.
Published in:
Human Heredity, 2004, v. 57, n. 2, p. 69, doi. 10.1159/000077544
By:
- Pitkäniemi, Janne;
- Hakulinen, Timo;
- Näsänen, Jurkka;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko
Publication type:
Article
Estimation of Transmission Probabilities in Families Ascertained through a Proband with Variable Age-at-Onset Disease: Application to the HLA A, B and DR Loci in Finnish Families with Type 1 Diabetes.
Published in:
Human Heredity, 2000, v. 50, n. 5, p. 308, doi. 10.1159/000022933
By:
- Pitkäniemi, Janne;
- Onkamo, Päivi;
- Arjas, Elja;
- Tuomilehto-Wolf, Eva;
- Tuomilehto, Jaakko
Publication type:
Article
Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene ( IDDM6 ).
Published in:
Human Molecular Genetics, 1998, v. 7, n. 3, p. 517, doi. 10.1093/hmg/7.3.517
By:
- Merriman, Tony R.;
- Eaves, Iain A.;
- Twells, Rebecca C. J.;
- Merriman, Marilyn E.;
- Danoy, Patrick A. C.;
- Muxworthy, Claire E.;
- Hunter, Kara M. D.;
- Cox, Roger D.;
- Cucca, Francesco;
- McKinney, Patricia A.;
- Shield, Julian P. H.;
- Baum, J. David;
- Tuomilehto, Jaakko;
- Tuomilehto‐Wolf, Eva;
- Ionesco‐Tirgoviste, C.;
- Joner, Geir;
- Thorsby, Erik;
- Undlien, Dag E.;
- Pociot, Flemming;
- Nerup, Jørn
Publication type:
Article

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