Works by Tsirigos, Aristotelis


Results: 68
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    GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment.

    Published in:
    Science Immunology, 2019, v. 4, n. 42, p. 1, doi. 10.1126/sciimmunol.aax8189
    By:
    • Halaby, Marie Jo;
    • Hezaveh, Kebria;
    • Lamorte, Sara;
    • Ciudad, M. Teresa;
    • Kloetgen, Andreas;
    • MacLeod, Bethany L.;
    • Mengdi Guo;
    • Chakravarthy, Ankur;
    • Da Silva Medina, Tiago;
    • Ugel, Stefano;
    • Tsirigos, Aristotelis;
    • Bronte, Vincenzo;
    • Munn, David H.;
    • Pugh, Trevor J.;
    • De Carvalho, Daniel D.;
    • Butler, Marcus O.;
    • Ohashi, Pamela S.;
    • Brooks, David G.;
    • McGaha, Tracy L.
    Publication type:
    Article
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    Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.

    Published in:
    Nature Medicine, 2012, v. 18, n. 2, p. 298, doi. 10.1038/nm.2651
    By:
    • Ntziachristos, Panagiotis;
    • Tsirigos, Aristotelis;
    • Vlierberghe, Pieter Van;
    • Nedjic, Jelena;
    • Trimarchi, Thomas;
    • Flaherty, Maria Sol;
    • Ferres-Marco, Dolors;
    • da Ros, Vanina;
    • Tang, Zuojian;
    • Siegle, Jasmin;
    • Asp, Patrik;
    • Hadler, Michael;
    • Rigo, Isaura;
    • Keersmaecker, Kim De;
    • Patel, Jay;
    • Huynh, Tien;
    • Utro, Filippo;
    • Poglio, Sandrine;
    • Samon, Jeremy B;
    • Paietta, Elisabeth
    Publication type:
    Article
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    Modulating mitofusins to control mitochondrial function and signaling.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31324-1
    By:
    • Zacharioudakis, Emmanouil;
    • Agianian, Bogos;
    • Kumar MV, Vasantha;
    • Biris, Nikolaos;
    • Garner, Thomas P.;
    • Rabinovich-Nikitin, Inna;
    • Ouchida, Amanda T.;
    • Margulets, Victoria;
    • Nordstrøm, Lars Ulrik;
    • Riley, Joel S.;
    • Dolgalev, Igor;
    • Chen, Yun;
    • Wittig, Andre J. H.;
    • Pekson, Ryan;
    • Mathew, Chris;
    • Wei, Peter;
    • Tsirigos, Aristotelis;
    • Tait, Stephen W. G.;
    • Kirshenbaum, Lorrie A.;
    • Kitsis, Richard N.
    Publication type:
    Article
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    An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36967-2
    By:
    • Davalos, Veronica;
    • Lovell, Claudia D.;
    • Von Itter, Richard;
    • Dolgalev, Igor;
    • Agrawal, Praveen;
    • Baptiste, Gillian;
    • Kahler, David J.;
    • Sokolova, Elena;
    • Moran, Sebastian;
    • Piqué, Laia;
    • Vega-Saenz de Miera, Eleazar;
    • Fontanals-Cirera, Barbara;
    • Karz, Alcida;
    • Tsirigos, Aristotelis;
    • Yun, Chi;
    • Darvishian, Farbod;
    • Etchevers, Heather C.;
    • Osman, Iman;
    • Esteller, Manel;
    • Schober, Markus
    Publication type:
    Article
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    Understanding the "lethal" drivers of tumor-stroma co-evolution.

    Published in:
    Cancer Biology & Therapy, 2010, v. 10, n. 6, p. 537, doi. 10.4161/cbt.10.6.13370
    By:
    • Lisanti, Michael P.;
    • Martinez-Outschoorn, Ubaldo E.;
    • Chiavarina, Barbara;
    • Pavlides, Stephanos;
    • Whitaker-Menezes, Diana;
    • Tsirigos, Aristotelis;
    • Witkiewicz, Agnieszka;
    • Lin, Zhao;
    • Balliet, Renee;
    • Howell, Anthony;
    • Sotgia, Federica
    Publication type:
    Article
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    Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer.

    Published in:
    2018
    By:
    • Tsay, Jun-Chieh J;
    • Wu, Benjamin G;
    • Badri, Michelle H;
    • Clemente, Jose C;
    • Shen, Nan;
    • Meyn, Peter;
    • Li, Yonghua;
    • Yie, Ting-An;
    • Lhakhang, Tenzin;
    • Olsen, Evan;
    • Murthy, Vivek;
    • Michaud, Gaetane;
    • Sulaiman, Imran;
    • Tsirigos, Aristotelis;
    • Heguy, Adriana;
    • Pass, Harvey;
    • Weiden, Michael D;
    • Rom, William N;
    • Sterman, Daniel H;
    • Bonneau, Richard
    Publication type:
    journal article
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    Mitochondria "fuel" breast cancer metabolism.

    Published in:
    Cell Cycle, 2012, v. 11, n. 23, p. 4390, doi. 10.4161/cc.22777
    By:
    • Sotgia, Federica;
    • Whitaker-Menezes, Diana;
    • Martinez-Outschoorn, Ubaldo E.;
    • Salem, Ahmed F.;
    • Tsirigos, Aristotelis;
    • Lamb, Rebecca;
    • Sneddon, Sharon;
    • Hulit, James;
    • Howell, Anthony;
    • Lisanti, Michael P.
    Publication type:
    Article
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    Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production.

    Published in:
    Cell Cycle, 2012, v. 11, n. 12, p. 2285, doi. 10.4161/cc.20718
    By:
    • Capparelli, Claudia;
    • Guido, Carmela;
    • Whitaker-Menezes, Diana;
    • Bonuccelli, Gloria;
    • Balliet, Renee;
    • Pestell, Timothy G.;
    • Goldberg, Allison F.;
    • Pestell, Richard G.;
    • Howell, Anthony;
    • Sneddon, Sharon;
    • Birbe, Ruth;
    • Tsirigos, Aristotelis;
    • Martinez-Outschoorn, Ubaldo;
    • Sotgia, Federica;
    • Lisanti, Michael P.
    Publication type:
    Article
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    Is cancer a metabolic rebellion against host aging?.

    Published in:
    Cell Cycle, 2012, v. 11, n. 2, p. 253, doi. 10.4161/cc.11.2.19006
    By:
    • Ertel, Adam;
    • Tsirigos, Aristotelis;
    • Whitaker-Menezes, Diana;
    • Birbe, Ruth C.;
    • Pavlides, Stephanos;
    • Martinez-Outschoorn, Ubaldo E.;
    • Pestell, Richard G.;
    • Howell, Anthony;
    • Sotgia, Federica;
    • Lisanti, Michael P.
    Publication type:
    Article
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    Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ.

    Published in:
    Cell Cycle, 2011, v. 10, n. 23, p. 4047, doi. 10.4161/cc.10.23.18151
    By:
    • Whitaker-Menezes, Diana;
    • Martinez-Outschoorn, Ubaldo E.;
    • Flomenberg, Neal;
    • Birbe, Ruth C.;
    • Witkiewicz, Agnieszka K.;
    • Howell, Anthony;
    • Pavlides, Stephanos;
    • Tsirigos, Aristotelis;
    • Ertel, Adam;
    • Pestell, Richard G.;
    • Broda, Paolo;
    • Minetti, Carlo;
    • Lisanti, Michael P.;
    • Sotgia, Federica
    Publication type:
    Article
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    Loss of Notch signaling in skeletal stem cells enhances bone formation with aging.

    Published in:
    Bone Research, 2023, v. 11, n. 1, p. 1, doi. 10.1038/s41413-023-00283-8
    By:
    • Remark, Lindsey H.;
    • Leclerc, Kevin;
    • Ramsukh, Malissa;
    • Lin, Ziyan;
    • Lee, Sooyeon;
    • Dharmalingam, Backialakshmi;
    • Gillinov, Lauren;
    • Nayak, Vasudev V.;
    • El Parente, Paulo;
    • Sambon, Margaux;
    • Atria, Pablo J.;
    • Ali, Mohamed A. E.;
    • Witek, Lukasz;
    • Castillo, Alesha B.;
    • Park, Christopher Y;
    • Adams, Ralf H.;
    • Tsirigos, Aristotelis;
    • Morgani, Sophie M.;
    • Leucht, Philipp
    Publication type:
    Article
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    MetFinder: A Tool for Automated Quantitation of Metastatic Burden in Histological Sections From Preclinical Models.

    Published in:
    Pigment Cell & Melanoma Research, 2025, v. 38, n. 1, p. 1, doi. 10.1111/pcmr.13195
    By:
    • Karz, Alcida;
    • Coudray, Nicolas;
    • Bayraktar, Erol;
    • Galbraith, Kristyn;
    • Jour, George;
    • Shadaloey, Arman Alberto Sorin;
    • Eskow, Nicole;
    • Rubanov, Andrey;
    • Navarro, Maya;
    • Moubarak, Rana;
    • Baptiste, Gillian;
    • Levinson, Grace;
    • Mezzano, Valeria;
    • Alu, Mark;
    • Loomis, Cynthia;
    • Lima, Daniel;
    • Rubens, Adam;
    • Jilaveanu, Lucia;
    • Tsirigos, Aristotelis;
    • Hernando, Eva
    Publication type:
    Article
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    The autophagic tumor stroma model of cancer or "battery-operated tumor growth.".

    Published in:
    Cell Cycle, 2010, v. 9, n. 21, p. 4297, doi. 10.4161/cc.9.21.13817
    By:
    • Martinez-Outschoorn, Ubaldo E.;
    • Whitaker-Menezes, Diana;
    • Pavlides, Stephanos;
    • Chiavarina, Barbara;
    • Bonuccelli, Gloria;
    • Trimmer, Casey;
    • Tsirigos, Aristotelis;
    • Migneco, Gemma;
    • Witkiewicz, Agnieszka K.;
    • Balliet, Renee;
    • Mercier, Isabelle;
    • Chengwang Wang;
    • Flomenberg, Neal;
    • Howell, Anthony;
    • Zhao Lin;
    • Caro, Jaime;
    • Pestell, Richard G.;
    • Sotgia, Federica;
    • Lisanti, Michael P.
    Publication type:
    Article
    48

    The autophagic tumor stroma model of cancer.

    Published in:
    Cell Cycle, 2010, v. 9, n. 17, p. 3485, doi. 10.4161/cc.9.17.12721
    By:
    • Pavlides, Stephanos;
    • Tsirigos, Aristotelis;
    • Migneco, Gemma;
    • Whitaker-Menezes, Diana;
    • Chiavarina, Barbara;
    • Flomenberg, Neal;
    • Frank, Philippe G.;
    • Casimiro, Mathew C.;
    • Wang, Chenguang;
    • Pestell, Richard G.;
    • Martinez-Outschoorn, Ubaldo E.;
    • Howell, Anthony;
    • Sotgia, Federica;
    • Lisanti, Michael P.
    Publication type:
    Article
    49

    Ketones and lactate "fuel" tumor growth and metastasis.

    Published in:
    Cell Cycle, 2010, v. 9, n. 17, p. 3506, doi. 10.4161/cc.9.17.12731
    By:
    • Bonuccelli, Gloria;
    • Tsirigos, Aristotelis;
    • Whitaker-Menezes, Diana;
    • Pavlides, Stephanos;
    • Pestell, Richard G.;
    • Chiavarina, Barbara;
    • Frank, Philippe G.;
    • Flomenberg, Neal;
    • Howell, Anthony;
    • Martinez-Outschoorn, Ubaldo E.;
    • Sotgia, Federica;
    • Lisanti, Michael P.
    Publication type:
    Article
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