Works by Tschöp, Matthias H


Results: 114
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    UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals.

    Published in:
    Nature, 2008, v. 454, n. 7206, p. 846, doi. 10.1038/nature07181
    By:
    • Andrews, Zane B.;
    • Liu, Zhong-Wu;
    • Walllingford, Nicholas;
    • Erion, Derek M.;
    • Borok, Erzsebet;
    • Friedman, Jeffery M.;
    • Tschöp, Matthias H.;
    • Shanabrough, Marya;
    • Cline, Gary;
    • Shulman, Gerald I.;
    • Coppola, Anna;
    • Gao, Xiao-Bing;
    • Horvath, Tamas L.;
    • Diano, Sabrina
    Publication type:
    Article
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    Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21.

    Published in:
    Journal of Peptide Science, 2012, v. 18, n. 6, p. 383, doi. 10.1002/psc.2408
    By:
    • Müller, Timo D.;
    • Sullivan, Lorraine M.;
    • Habegger, Kirk;
    • Yi, Chun-Xia;
    • Kabra, Dhiraj;
    • Grant, Erin;
    • Ottaway, Nickki;
    • Krishna, Radha;
    • Holland, Jenna;
    • Hembree, Jazzminn;
    • Perez-Tilve, Diego;
    • Pfluger, Paul T.;
    • DeGuzman, Michael J.;
    • Siladi, Marc E.;
    • Kraynov, Vadim S.;
    • Axelrod, Douglas W.;
    • DiMarchi, Richard;
    • Pinkstaff, Jason K.;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    Play down protein to play up metabolism?

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3691, doi. 10.1172/JCI77508
    By:
    • Müller, Timo D.;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    Obesity is associated with hypothalamic injury in rodents and humans.

    Published in:
    Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 1, doi. 10.1172/JCI59660
    By:
    • Thaler, Joshua P.;
    • Chun-Xia Yi;
    • Schur, Ellen A.;
    • Guyenet, Stephan J.;
    • Hwang, Bang H.;
    • Dietrich, Marcelo O.;
    • Xiaolin Zhao;
    • Sarruf, David A.;
    • Izgur, Vitaly;
    • Maravilla, Kenneth R.;
    • Nguyen, Hong T.;
    • Fischer, Jonathan D.;
    • Matsen, Miles E.;
    • Wisse, Brent E.;
    • Morton, Gregory J.;
    • Horvath, Tamas L.;
    • Baskin, Denis G.;
    • Tschöp, Matthias H.;
    • Schwartz, Michael W.
    Publication type:
    Article
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    Ghrelin action in the brain controls adipocyte metabolism.

    Published in:
    Journal of Clinical Investigation, 2006, v. 116, n. 7, p. 1983, doi. 10.1172/JCI25811
    By:
    • Theander-Carrillo, Claudia;
    • Wiedmer, Petra;
    • Cettour-Rose, Philippe;
    • Nogueiras, Ruben;
    • Perez-Tilve, Diego;
    • Pfluger, Paul;
    • Castaneda, Tamara R.;
    • Muzzin, Patrick;
    • Schürmann, Annette;
    • Szanto, Ildiko;
    • Tschöp, Matthias H.;
    • Rohner-Jeanrenaud, Françoise
    Publication type:
    Article
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    The insulin-like growth factor I receptor regulates glucose transport by astrocytes.

    Published in:
    Glia (0894-1491), 2016, v. 64, n. 11, p. 1962, doi. 10.1002/glia.23035
    By:
    • Hernandez ‐ Garzón, Edwin;
    • Fernandez, Ana M.;
    • Perez ‐ Alvarez, Alberto;
    • Genis, Laura;
    • Bascuñana, Pablo;
    • Fernandez de la Rosa, Ruben;
    • Delgado, Mercedes;
    • Angel Pozo, Miguel;
    • Moreno, Estefania;
    • McCormick, Peter J.;
    • Santi, Andrea;
    • Trueba ‐ Saiz, Angel;
    • Garcia ‐ Caceres, Cristina;
    • Tschöp, Matthias H.;
    • Araque, Alfonso;
    • Martin, Eduardo D.;
    • Torres Aleman, Ignacio
    Publication type:
    Article
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    Hormones and diet, but not body weight, control hypothalamic microglial activity.

    Published in:
    Glia (0894-1491), 2014, v. 62, n. 1, p. 17, doi. 10.1002/glia.22580
    By:
    • Gao, Yuanqing;
    • Ottaway, Nickki;
    • Schriever, Sonja C.;
    • Legutko, Beata;
    • García‐Cáceres, Cristina;
    • Fuente, Esther;
    • Mergen, Clarita;
    • Bour, Susanne;
    • Thaler, Joshua P.;
    • Seeley, Randy J.;
    • Filosa, Jessica;
    • Stern, Javier E.;
    • Perez‐Tilve, Diego;
    • Schwartz, Michael W.;
    • Tschöp, Matthias H.;
    • Yi, Chun‐Xia
    Publication type:
    Article
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    Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36148-1
    By:
    • Kulaj, Konxhe;
    • Harger, Alexandra;
    • Bauer, Michaela;
    • Caliskan, Özüm S.;
    • Gupta, Tilak Kumar;
    • Chiang, Dapi Menglin;
    • Milbank, Edward;
    • Reber, Josefine;
    • Karlas, Angelos;
    • Kotzbeck, Petra;
    • Sailer, David N.;
    • Volta, Francesco;
    • Lutter, Dominik;
    • Prakash, Sneha;
    • Merl-Pham, Juliane;
    • Ntziachristos, Vasilis;
    • Hauner, Hans;
    • Pfaffl, Michael W.;
    • Tschöp, Matthias H.;
    • Müller, Timo D.
    Publication type:
    Article
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    Ghrelin Enhances Olfactory Sensitivity and Exploratory Sniffing in Rodents and Humans.

    Published in:
    Journal of Neuroscience, 2011, v. 31, n. 15, p. 5841, doi. 10.1523/JNEUROSCI.5680-10.2011
    By:
    • Tong, Jenny;
    • Mannea, Erica;
    • Aimé, Pascaline;
    • Pfluger, Paul T.;
    • Chun-Xia Yi;
    • Castaneda, Tamara R.;
    • Davis, Harold W.;
    • Xueying Ren;
    • Pixley, Sarah;
    • Benoit, Stephen;
    • Julliard, Karyne;
    • Woods, Stephen C.;
    • Horvath, Tamas L.;
    • Sleeman, Mark M.;
    • D'Alessio, David;
    • Obici, Silvana;
    • Frank, Robert;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    CNS Leptin Action Modulates Immune Response and Survival in Sepsis.

    Published in:
    Journal of Neuroscience, 2010, v. 30, n. 17, p. 6036, doi. 10.1523/JNEUROSCI.4875-09.2010
    By:
    • Tschöp, Johannes;
    • Nogueiras, Ruben;
    • Haas-Lockie, Sarah;
    • Kasten, Kevin R.;
    • Castañeda, Tamara R.;
    • Huber, Nadine;
    • Guanciale, Kelsey;
    • Perez-Tilve, Diego;
    • Habegger, Kirk;
    • Ottaway, Nickki;
    • Woods, Stephen C.;
    • Oldfield, Brian;
    • Clarke, Iain;
    • Chua Jr., Streamson;
    • Sadaf Farooqi, I.;
    • O'Rahilly, Stephen;
    • Caldwell, Charles C.;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    Direct Control of Peripheral Lipid Deposition by CNS GLP-1 Receptor Signaling Is Mediated by the Sympathetic Nervous System and Blunted in Diet-Induced Obesity.

    Published in:
    Journal of Neuroscience, 2009, v. 29, n. 18, p. 5916, doi. 10.1523/JNEUROSCI.5977-08.2009
    By:
    • Nogueiras, Ruben;
    • Pérez-Tilve, Diego;
    • Veyrat-Durebex, Christelle;
    • Morgan, Donald A.;
    • Varela, Luis;
    • Haynes, William G.;
    • Patterson, James T.;
    • Disse, Emmanuel;
    • Pfluger, Paul T.;
    • López, Miguel;
    • Woods, Stephen C.;
    • DiMarchi, Richard;
    • Diéguez, Carlos;
    • Rahmouni, Kamal;
    • Rohner-Jeanrenaud, Françoise;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    Dusp8 affects hippocampal size and behavior in mice and humans.

    Published in:
    Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55527-7
    By:
    • Baumann, Peter;
    • Schriever, Sonja C.;
    • Kullmann, Stephanie;
    • Zimprich, Annemarie;
    • Feuchtinger, Annette;
    • Amarie, Oana;
    • Peter, Andreas;
    • Walch, Axel;
    • Gailus-Durner, Valerie;
    • Fuchs, Helmut;
    • Hrabě de Angelis, Martin;
    • Wurst, Wolfgang;
    • Tschöp, Matthias H.;
    • Heni, Martin;
    • Hölter, Sabine M.;
    • Pfluger, Paul T.
    Publication type:
    Article
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    Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.

    Published in:
    Nature Neuroscience, 2014, v. 17, n. 7, p. 908, doi. 10.1038/nn.3725
    By:
    • Kim, Jae Geun;
    • Suyama, Shigetomo;
    • Koch, Marco;
    • Jin, Sungho;
    • Argente-Arizon, Pilar;
    • Argente, Jesús;
    • Liu, Zhong-Wu;
    • Zimmer, Marcelo R;
    • Jeong, Jin Kwon;
    • Szigeti-Buck, Klara;
    • Gao, Yuanqing;
    • Garcia-Caceres, Cristina;
    • Yi, Chun-Xia;
    • Salmaso, Natalina;
    • Vaccarino, Flora M;
    • Chowen, Julie;
    • Diano, Sabrina;
    • Dietrich, Marcelo O;
    • Tschöp, Matthias H;
    • Horvath, Tamas L
    Publication type:
    Article
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    Melanocortin signaling in the CNS directly regulates circulating cholesterol.

    Published in:
    Nature Neuroscience, 2010, v. 13, n. 7, p. 877, doi. 10.1038/nn.2569
    By:
    • Perez-Tilve, Diego;
    • Hofmann, Susanna M.;
    • Basford, Joshua;
    • Nogueiras, Ruben;
    • Pfluger, Paul T.;
    • Patterson, James T.;
    • Grant, Erin;
    • Wilson-Perez, Hilary E.;
    • Granholm, Norman A.;
    • Arnold, Myrtha;
    • Trevaskis, James L.;
    • Butler, Andrew A.;
    • Davidson, William S.;
    • Woods, Stephen C.;
    • Benoit, Stephen C.;
    • Sleeman, Mark W.;
    • DiMarchi, Richard D.;
    • Hui, David Y.;
    • Tschöp, Matthias H.
    Publication type:
    Article
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    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.

    Published in:
    Diabetologia, 2020, v. 63, n. 6, p. 1236, doi. 10.1007/s00125-020-05117-4
    By:
    • Jall, Sigrid;
    • De Angelis, Meri;
    • Lundsgaard, Anne-Marie;
    • Fritzen, Andreas M.;
    • Nicolaisen, Trine S.;
    • Klein, Anders B.;
    • Novikoff, Aaron;
    • Sachs, Stephan;
    • Richter, Erik A.;
    • Kiens, Bente;
    • Schramm, Karl-Werner;
    • Tschöp, Matthias H.;
    • Stemmer, Kerstin;
    • Clemmensen, Christoffer;
    • Müller, Timo D.;
    • Kleinert, Maximilian
    Publication type:
    Article
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    TNFα drives mitochondrial stress in POMC neurons in obesity.

    Published in:
    Nature Communications, 2017, v. 8, n. 5, p. 15143, doi. 10.1038/ncomms15143
    By:
    • Yi, Chun-Xia;
    • Walter, Marc;
    • Gao, Yuanqing;
    • Pitra, Soledad;
    • Legutko, Beata;
    • Kälin, Stefanie;
    • Layritz, Clarita;
    • García-Cáceres, Cristina;
    • Bielohuby, Maximilian;
    • Bidlingmaier, Martin;
    • Woods, Stephen C.;
    • Ghanem, Alexander;
    • Conzelmann, Karl-Klaus;
    • Stern, Javier E.;
    • Jastroch, Martin;
    • Tschöp, Matthias H.
    Publication type:
    Article