Works by Tsai, Li-Huei

Results: 88

14-3-3e is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome.

Published in:

Nature Genetics, 2003, v. 34, n. 3, p. 274, doi. 10.1038/ng1169

By:

Toyo-oka, Kazuhito;
Shionoya, Aki;
Gambello, Michael J;
Cardoso, Carlos;
Leventer, Richard;
Ward, Heather L;
Ayala, Ramses;
Tsai, Li-Huei;
Dobyns, William;
Ledbetter, David;
Hirotsune, Shinji;
Wynshaw-Boris, Anthony

Publication type:

Article

3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0599-8

By:

Gail Canter, Rebecca;
Huang, Wen-Chin;
Choi, Heejin;
Wang, Jun;
Ashley Watson, Lauren;
Yao, Christine G.;
Abdurrob, Fatema;
Bousleiman, Stephanie M.;
Young, Jennie Z.;
Bennett, David A.;
Delalle, Ivana;
Chung, Kwanghun;
Tsai, Li-Huei

Publication type:

Article

Cdk5 at the junction.

Published in:

Nature Neuroscience, 2001, v. 4, n. 4, p. 340, doi. 10.1038/85967

By:

Lee, Ming-Sum;
Tsai, Li-Huei

Publication type:

Article

Axon selection.

Published in:

Communicative & Integrative Biology, 2011, v. 4, n. 3, p. 304, doi. 10.4161/cib.4.3.14781

By:

Calderon de Anda, Froylan;
Tsai, Li-Huei

Publication type:

Article

Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075538

By:

Bosutti, Alessandra;
Qi, Jie;
Pennucci, Roberta;
Bolton, David;
Matou, Sabine;
Ali, Kamela;
Tsai, Li-Huei;
Krupinski, Jerzy;
Petcu, Eugene B.;
Montaner, Joan;
Al Baradie, Raid;
Caccuri, Francesca;
Caruso, Arnaldo;
Alessandri, Giulio;
Kumar, Shant;
Rodriguez, Cristina;
Martinez-Gonzalez, Jose;
Slevin, Mark

Publication type:

Article

Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025735

By:

Guan, Ji-Song;
Su, Susan C.;
Gao, Jun;
Joseph, Nadine;
Xie, Zhigang;
Zhou, Ying;
Durak, Omer;
Zhang, Lei;
Zhu, J. Julius;
Clauser, Karl R.;
Carr, Steven A.;
Tsai, Li-Huei

Publication type:

Article

Reelin and Cyclin-Dependent Kinase 5-Dependent Signals Cooperate in Regulating Neuronal Migration and Synaptic Transmission.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 8, p. 1897, doi. 10.1523/JNEUROSCI.4084-03.2004

By:

Beffert, Uwe;
Weeber, Edwin J.;
Morfini, Gerardo;
Ko, Jane;
Brady, Scott T.;
Tsai, Li-Huei;
Sweatt, J. David;
Herz, Joachim

Publication type:

Article

How MicroRNAs Are Involved in Splitting the Mind.

Published in:

2016

By:

Tsai, Li-Huei;
Siegert, Sandra

Publication type:

journal article

Gamma entrainment using audiovisual stimuli alleviates chemobrain pathology and cognitive impairment induced by chemotherapy in mice.

Published in:

Science Translational Medicine, 2024, v. 16, n. 737, p. 1, doi. 10.1126/scitranslmed.adf4601

By:

Kim, TaeHyun;
James, Benjamin T.;
Kahn, Martin C.;
Blanco-Duque, Cristina;
Abdurrob, Fatema;
Islam, Md Rezaul;
Lavoie, Nicolas S.;
Kellis, Manolis;
Tsai, Li-Huei

Publication type:

Article

Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease.

Published in:

Science Translational Medicine, 2023, v. 15, n. 692, p. 1, doi. 10.1126/scitranslmed.abq1019

By:

Huang, Wen-Chin;
Peng, Zhuyu;
Murdock, Mitchell H.;
Liu, Liwang;
Mathys, Hansruedi;
Davila-Velderrain, Jose;
Jiang, Xueqiao;
Chen, Maggie;
Ng, Ayesha P.;
Kim, TaeHyun;
Abdurrob, Fatema;
Gao, Fan;
Bennett, David A.;
Kellis, Manolis;
Tsai, Li-Huei

Publication type:

Article

MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration.

Published in:

Science Translational Medicine, 2021, v. 13, n. 618, p. 1, doi. 10.1126/scitranslmed.abd7695

By:

Barker, Scarlett J.;
Raju, Ravikiran M.;
Milman, Noah E.P.;
Wang, Jun;
Davila-Velderrain, Jose;
Gunter-Rahman, Fatima;
Parro, Cameron C.;
Bozzelli, P. Lorenzo;
Abdurrob, Fatema;
Abdelaal, Karim;
Bennett, David A.;
Kellis, Manolis;
Tsai, Li-Huei

Publication type:

Article

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia.

Published in:

Science Translational Medicine, 2021, v. 13, n. 583, p. 1, doi. 10.1126/scitranslmed.aaz4564

By:

Sienski, Grzegorz;
Narayan, Priyanka;
Bonner, Julia Maeve;
Kory, Nora;
Boland, Sebastian;
Arczewska, Aleksandra A.;
Ralvenius, William T.;
Akay, Leyla;
Lockshin, Elana;
He, Liang;
Milo, Blerta;
Graziosi, Agnese;
Baru, Valeriya;
Lewis, Caroline A.;
Kellis, Manolis;
Sabatini, David M.;
Tsai, Li-Huei;
Lindquist, Susan

Publication type:

Article

Loss of Cyclin-Dependent Kinase 5 from Parvalbumin Interneurons Leads to Hyperinhibition, Decreased Anxiety, and Memory Impairment.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 6, p. 2372, doi. 10.1523/JNEUROSCI.0969-14.2015

By:

Rudenko, Andrii;
Seo, Jinsoo;
Hu, Ji;
Su, Susan C.;
de Anda, Froylan Calderon;
Durak, Omer;
Ericsson, Maria;
Carlén, Marie;
Tsai, Li-Huei

Publication type:

Article

A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 21, p. 8951, doi. 10.1523/JNEUROSCI.5657-12.2013

By:

Graff, Johannes;
Kahn, Martin;
Samiei, Alireza;
Jun Gao;
Ota, Kristie T.;
Rei, Damien;
Tsai, Li-Huei

Publication type:

Article

Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease.

Published in:

Annals of Neurology, 2024, v. 95, n. 4, p. 625, doi. 10.1002/ana.26864

By:

Vance, Jeffery M.;
Farrer, Lindsay A.;
Huang, Yadong;
Cruchaga, Carlos;
Hyman, Bradley T.;
Pericak‐Vance, Margaret A.;
Goate, Alison M.;
Greicius, Michael D.;
Griswold, Anthony J.;
Haines, Jonathan L.;
TCW, Julia;
Schellenberg, Gerard D.;
Tsai, Li‐Huei;
Herz, Joachim;
Holtzman, David M.

Publication type:

Article

Proteomics analysis characterizing new markers related to Aβ plaques and tau tangles pathologies.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.091288

By:

Binette, Alexa Pichet;
Wennström, Malin;
Strandberg, Olof;
Mathys, Hansruedi;
Tsai, Li‐Huei;
Mattsson‐Carlgren, Niklas;
Stomrud, Erik;
Janelidze, Shorena;
Vogel, Jacob W.;
Hansson, Oskar

Publication type:

Article

Deciphering the molecular and cellular underpinnings of cognitive resilience in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.090374

By:

Castanho, Isabel;
Yeganeh, Pourya Naderi;
Boix, Carles A;
Mathys, Hansruedi;
Prokopenko, Dmitry;
White, Bartholomew;
Morgan, Sarah;
Lange, Christoph;
Bennett, David A.;
Bertram, Lars;
Tanzi, Rudolph E.;
Tsai, Li‐Huei;
Kellis, Manolis;
Hide, Winston

Publication type:

Article

Lithium protects against ApoE4 mediated calcium dysregulation and mitochondrial dysfunction and cell damage in iPSCs from a sporadic Alzheimer's disease patient.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082765

By:

Liang, Ge;
Anchipolovsky, Samuel;
Zhang, Roland;
Das, Ipsita;
Ayala, Benjamin;
Xu, Xandro;
Tsai, Li‐Huei;
Wei, Huafeng

Publication type:

Article

Multi‐polygenic score model informs the genetic basis of heterogeneity in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079231

By:

Tanigawa, Yosuke;
Sun, Na;
Li, William F;
Boix, Carles A;
Galani, Kyriaki;
Mathys, Hansruedi;
Bennett, David A. A;
Tsai, Li‐Huei;
Kellis, Manolis

Publication type:

Article

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071948

By:

Tsai, Li‐Huei;
Akay, Leyla A;
Blanchard, Joel;
Von Maydell, Djuna K;
Kellis, Manolis;
Bennett, David A. A;
Davila, Jose

Publication type:

Article

Multi‐polygenic score model informs the genetic basis of heterogeneity in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079231

By:

Tanigawa, Yosuke;
Sun, Na;
Li, William F;
Boix, Carles A;
Galani, Kyriaki;
Mathys, Hansruedi;
Bennett, David A. A;
Tsai, Li‐Huei;
Kellis, Manolis

Publication type:

Article

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071948

By:

Tsai, Li‐Huei;
Akay, Leyla A;
Blanchard, Joel;
Von Maydell, Djuna K;
Kellis, Manolis;
Bennett, David A. A;
Davila, Jose

Publication type:

Article

Gamma frequency sensory stimulation prevents brain atrophy, improves sleep and memory in probable mild Alzheimer's patients.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054218

By:

Chan, Diane;
Suk, Ho‐Jun;
Jackson, Brennan L;
Milman, Noah;
Stark, Danielle;
Fernandez, Vanesa;
Banerjee, Arit;
Kitchener, Erin;
Klerman, Elizabeth B;
Boyden, Edward S;
Brown, Emery N;
Dickerson, Brad C.;
Tsai, Li‐Huei

Publication type:

Article

A novel PU.1 inhibitor for the treatment of Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052667

By:

Ralvenius, William T;
Tsai, Li‐Huei;
Woolf, Hannah;
Cam, Hugh;
Mungenast, Alison

Publication type:

Article

F1‐07‐04: USING HUMAN IPSC MODELS TO PROBE TREM2 FUNCTION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P189, doi. 10.1016/j.jalz.2019.06.4396

By:

Penney, Jay;
Elmsaouri, Sara;
Milo, Blerta;
Gao, Fan;
Tsai, Li-Huei

Publication type:

Article

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration.

Published in:

Molecular Systems Biology, 2020, v. 16, n. 12, p. 1, doi. 10.15252/msb.20209819

By:

Morshed, Nader;
Ralvenius, William T;
Nott, Alexi;
Watson, L Ashley;
Rodriguez, Felicia H;
Akay, Leyla A;
Joughin, Brian A;
Pao, Ping‐Chieh;
Penney, Jay;
LaRocque, Lauren;
Mastroeni, Diego;
Tsai, Li‐Huei;
White, Forest M

Publication type:

Article

Mechanisms of Age-Related Cognitive Change and Targets for Intervention: Epigenetics.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 7, p. 741, doi. 10.1093/gerona/gls110

By:

Kosik, Kenneth S.;
Rapp, Peter R.;
Raz, Naftali;
Small, Scott A.;
Sweatt, J. David;
Tsai, Li-Huei

Publication type:

Article

Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Published in:

2012

By:

Kosik KS;
Rapp PR;
Raz N;
Small SA;
Sweatt JD;
Tsai LH;
Kosik, Kenneth S;
Rapp, Peter R;
Raz, Naftali;
Small, Scott A;
Sweatt, J David;
Tsai, Li-Huei

Publication type:

journal article

The schizophrenia risk gene product miR-137 alters presynaptic plasticity.

Published in:

Nature Neuroscience, 2015, v. 18, n. 7, p. 1008, doi. 10.1038/nn.4023

By:

Siegert, Sandra;
Seo, Jinsoo;
Kwon, Ester J;
Rudenko, Andrii;
Cho, Sukhee;
Wang, Wenyuan;
Flood, Zachary;
Martorell, Anthony J;
Ericsson, Maria;
Mungenast, Alison E;
Tsai, Li-Huei

Publication type:

Article

Corrigendum: Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.

Published in:

Nature Neuroscience, 2014, v. 17, n. 12, p. 1840, doi. 10.1038/nn1214-1840a

By:

de Anda, Froylan Calderon;
Rosario, Ana Lucia;
Durak, Omer;
Tran, Tracy;
Gräff, Johannes;
Meletis, Konstantinos;
Rei, Damien;
Soda, Takahiro;
Madabhushi, Ram;
Ginty, David D;
Kolodkin, Alex L;
Tsai, Li-Huei

Publication type:

Article

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.

Published in:

Nature Neuroscience, 2013, v. 16, n. 10, p. 1383, doi. 10.1038/nn.3514

By:

Wang, Wen-Yuan;
Pan, Ling;
Su, Susan C;
Quinn, Emma J;
Sasaki, Megumi;
Jimenez, Jessica C;
Mackenzie, Ian R A;
Huang, Eric J;
Tsai, Li-Huei

Publication type:

Article

The Top3β way to untangle RNA.

Published in:

Nature Neuroscience, 2013, v. 16, n. 9, p. 1163, doi. 10.1038/nn.3506

By:

Nott, Alexi;
Tsai, Li-Huei

Publication type:

Article

SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons.

Published in:

Nature Neuroscience, 2013, v. 16, n. 8, p. 1008, doi. 10.1038/nn.3460

By:

Dobbin, Matthew M;
Madabhushi, Ram;
Pan, Ling;
Chen, Yue;
Kim, Dohoon;
Gao, Jun;
Ahanonu, Biafra;
Pao, Ping-Chieh;
Qiu, Yi;
Zhao, Yingming;
Tsai, Li-Huei

Publication type:

Article

DNA methylation in cognition comes of age.

Published in:

Nature Neuroscience, 2012, v. 15, n. 8, p. 1061, doi. 10.1038/nn.3169

By:

Su, Susan C;
Tsai, Li-Huei

Publication type:

Article

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.

Published in:

Nature Neuroscience, 2012, v. 15, n. 7, p. 1022, doi. 10.1038/nn.3141

By:

Calderon de Anda, Froylan;
Rosario, Ana Lucia;
Durak, Omer;
Tran, Tracy;
Gräff, Johannes;
Meletis, Konstantinos;
Rei, Damien;
Soda, Takahiro;
Madabhushi, Ram;
Ginty, David D;
Kolodkin, Alex L;
Tsai, Li-Huei

Publication type:

Article

A survey of Cdk5 activator p35 and p25 levels in Alzheimer’s disease brains

Published in:

FEBS Letters, 2002, v. 523, n. 1-3, p. 58, doi. 10.1016/S0014-5793(02)02934-4

By:

Tseng, Huang-Chun;
Zhou, Ying;
Shen, Yong;
Tsai, Li-Huei

Publication type:

Article

Glutamate Receptors in Alzheimer’s Disease: Mechanisms and Therapies.

Published in:

Neural Plasticity, 2016, p. 1, doi. 10.1155/2016/8256196

By:

Anggono, Victor;
Tsai, Li-Huei;
Götz, Jürgen

Publication type:

Article

S3-04-03: CDK5 and Aβ production

Published in:

2008

By:

Tsai, Li-Huei

Publication type:

Abstract

P1-416: APP processing and cell cycle reentry signaling pathways are involved in p25/cdk5-mediated neurodegeneration

Published in:

2006

By:

Kim, Dohoon;
Cruz, Jonathan C.;
Moy, Lily Y.;
Sun, Xiaoyan;
Bronson, Roderick T.;
Shen, Jie;
Tsai, Li-Huei

Publication type:

Abstract

S5-03-05: Symposia session

Published in:

2006

By:

Tsai, Li-Huei

Publication type:

Abstract

P1-416: APP processing and cell cycle reentry signaling pathways are involved in p25/cdk5-mediated neurodegeneration

Published in:

2006

By:

Kim, Dohoon;
Cruz, Jonathan C.;
Moy, Lily Y.;
Sun, Xiaoyan;
Bronson, Roderick T.;
Shen, Jie;
Tsai, Li-Huei

Publication type:

Abstract

S5-03-05: Symposia session

Published in:

2006

By:

Tsai, Li-Huei

Publication type:

Abstract

P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5.

Published in:

Nature, 1994, v. 371, n. 6496, p. 419, doi. 10.1038/371419a0

By:

Tsai, Li-Huei;
Delalle, Ivana

Publication type:

Article

Mechanisms of DNA damage‐mediated neurotoxicity in neurodegenerative disease.

Published in:

EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202154217

By:

Welch, Gwyneth;
Tsai, Li‐Huei

Publication type:

Article

On the resilience of remote traumatic memories against exposure therapy-mediated attenuation.

Published in:

EMBO Reports, 2014, v. 15, n. 8, p. 853, doi. 10.15252/embr.201438913

By:

Tsai, Li‐Huei;
Gräff, Johannes

Publication type:

Article

Life is a journey: a genetic look at neocortical development.

Published in:

2002

By:

Gupta, Amitabh;
Tsai, Li-Huei;
Wynshaw-Boris, Anthony

Publication type:

journal article

Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration.

Published in:

Cerebral Cortex, 2020, v. 30, n. 9, p. 4964, doi. 10.1093/cercor/bhaa088

By:

Kiroski, Ivana;
Jiang, Yulan;
Gavrilovici, Cezar;
Gao, Fan;
Lee, Sukyoung;
Scantlebury, Morris H;
Vandal, Milene;
Park, Sang Ki;
Tsai, Li-Huei;
Teskey, G Campbell;
Rho, Jong M;
Nguyen, Minh Dang

Publication type:

Article

Cyclin-Dependent Kinase 5 Permits Efficient Cytoskeletal Remodeling—a Hypothesis on Neuronal Migration.

Published in:

Cerebral Cortex, 2006, v. 16, n. suppl_1, p. i64, doi. 10.1093/cercor/bhj170

By:

Xie, Zhigang;
Samuels, Benjamin Adam;
Tsai, Li-Huei

Publication type:

Article

Cyclin-Dependent Kinase 5 Permits Efficient Cytoskeletal Remodeling—a Hypothesis on Neuronal Migration.

Published in:

Cerebral Cortex, 2006, v. 16, n. 1, p. i64, doi. 10.1093/cercor/bhj170

By:

Xie, Zhigang;
Samuels, Benjamin Adam;
Tsai, Li-Huei

Publication type:

Article

Three decades of Cdk5.

Published in:

Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00774-y

By:

Pao, Ping-Chieh;
Tsai, Li-Huei

Publication type:

Article