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A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Published in:
2010
By:
- Alimonti, Andrea;
- Nardella, Caterina;
- Zhenbang Chen;
- Clohessy, John G.;
- Carracedo, Arkaitz;
- Trotman, Lloyd C.;
- Ke Cheng;
- Varmeh, Shohreh;
- Kozma, Sara C.;
- Thomas, George;
- Rosivatz, Erika;
- Woscholski, Rudiger;
- Cognetti, Francesco;
- Scher, Howard I.;
- Pandolfi, Pier Paolo;
- Chen, Zhenbang;
- Cheng, Ke
Publication type:
journal article
Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells.
Published in:
PLoS ONE, 2023, v. 18, n. 10, p. 1, doi. 10.1371/journal.pone.0292483
By:
- Hillowe, Andrew;
- Gordon, Chris;
- Wang, Liqun;
- Rizzo, Robert C.;
- Trotman, Lloyd C.;
- Ojima, Iwao;
- Bialkowska, Agnieszka;
- Kaczocha, Martin
Publication type:
Article
Towards patient-based cancer therapeutics.
Published in:
2010
By:
- Schreiber, Stuart L.;
- Shamji, Alykhan F.;
- Clemons, Paul A.;
- Hon, Cindy;
- Koehler, Angela N.;
- Munoz, Benito;
- Palmer, Michelle;
- Stern, Andrew M.;
- Wagner, Bridget K.;
- Powers, Scott;
- Lowe, Scott W.;
- Guo, Xuecui;
- Krasnitz, Alex;
- Sawey, Eric T.;
- Sordella, Raffaella;
- Stein, Lincoln;
- Trotman, Lloyd C.;
- Califano, Andrea;
- Dalla-Favera, Riccardo;
- Ferrando, Adolfo
Publication type:
Opinion
Subtle variations in Pten dose determine cancer susceptibility.
Published in:
Nature Genetics, 2010, v. 42, n. 5, p. 454, doi. 10.1038/ng.556
By:
- Alimonti, Andrea;
- Carracedo, Arkaitz;
- Clohessy, John G.;
- Trotman, Lloyd C.;
- Nardella, Caterina;
- Egia, Ainara;
- Salmena, Leonardo;
- Sampieri, Katia;
- Haveman, William J.;
- Brogi, Edi;
- Richardson, Andrea L.;
- Jiangwen Zhang;
- Pandolfi, Pier Paolo
Publication type:
Article
FABP5 Inhibition against PTEN -Mutant Therapy Resistant Prostate Cancer.
Published in:
Cancers, 2024, v. 16, n. 1, p. 60, doi. 10.3390/cancers16010060
By:
- M. Swamynathan, Manojit;
- Mathew, Grinu;
- Aziz, Andrei;
- Gordon, Chris;
- Hillowe, Andrew;
- Wang, Hehe;
- Jhaveri, Aashna;
- Kendall, Jude;
- Cox, Hilary;
- Giarrizzo, Michael;
- Azabdaftari, Gissou;
- Rizzo, Robert C.;
- Diermeier, Sarah D.;
- Ojima, Iwao;
- Bialkowska, Agnieszka B.;
- Kaczocha, Martin;
- Trotman, Lloyd C.
Publication type:
Article
Identification of a tumour suppressor network opposing nuclear Akt function.
Published in:
Nature, 2006, v. 441, n. 7092, p. 523, doi. 10.1038/nature04809
By:
- Trotman, Lloyd C.;
- Alimonti, Andrea;
- Scaglioni, Pier Paolo;
- Koutcher, Jason A.;
- Cordon-Cardo, Carlos;
- Pandolfi, Pier Paolo
Publication type:
Article
Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1.
Published in:
Nature Cell Biology, 2001, v. 3, n. 12, p. 1092, doi. 10.1038/ncb1201-1092
By:
- Trotman, Lloyd C.;
- Mosberger, Nicole;
- Fornerod, Maarten;
- Stidwill, Robert P.;
- Greber, Urs F.
Publication type:
Article
Non-Classical Export of an Adenovirus Structural Protein.
Published in:
Traffic, 2003, v. 4, n. 6, p. 390, doi. 10.1034/j.1600-0854.2003.00094.x
By:
- Trotman, Lloyd C.;
- Achermann, Dominik P.;
- Keller, Stephan;
- Straub, Monika;
- Greber, Urs F.
Publication type:
Article
Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization.
Published in:
Nature Communications, 2017, v. 8, n. 2, p. 14370, doi. 10.1038/ncomms14370
By:
- Senturk, Serif;
- Shirole, Nitin H.;
- Nowak, Dawid G.;
- Corbo, Vincenzo;
- Pal, Debjani;
- Vaughan, Alexander;
- Tuveson, David A.;
- Trotman, Lloyd C.;
- Kinney, Justin B.;
- Sordella, Raffaella
Publication type:
Article
Docetaxel/cabazitaxel and fatty acid binding protein 5 inhibitors produce synergistic inhibition of prostate cancer growth.
Published in:
Prostate, 2020, v. 80, n. 1, p. 88, doi. 10.1002/pros.23921
By:
- Carbonetti, Gregory;
- Converso, Cynthia;
- Clement, Timothy;
- Wang, Changwei;
- Trotman, Lloyd C;
- Ojima, Iwao;
- Kaczocha, Martin
Publication type:
Article
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Published in:
Nature, 2005, v. 436, n. 7051, p. 725, doi. 10.1038/nature03918
By:
- Zhenbang Chen;
- Trotman, Lloyd C.;
- Shaffer, David;
- Hui-Kuan Lin;
- Dotan, Zohar A.;
- Niki, Masaru;
- Koutcher, Jason A.;
- Scher, Howard I.;
- Ludwig, Thomas;
- Gerald, William;
- Cordon-Cardo, Carlos;
- Pandolfi, Pier Paolo
Publication type:
Article
Pten Dose Dictates Cancer Progression in the Prostate.
Published in:
PLoS Biology, 2003, v. 1, n. 3, p. 385, doi. 10.1371/journal.pbio.0000059
By:
- Trotman, Lloyd C.;
- Niki, Masaru;
- Dotan, Zohar A.;
- Koutcher, Jason A.;
- Di Cristofano, Antinio;
- Xiao, Andrew;
- Khoo, Alan S.;
- Roy-Burman, Pradip;
- Greenberg, Norman M.;
- Van Dyke, Terry;
- Cordon-Cardo, Carlos;
- Pandolfi, Pier Paolo
Publication type:
Article
Pten Dose Dictates Cancer Progression in the Prostate.
Published in:
PLoS Biology, 2003, v. 1, n. 10, p. 1, doi. 10.1371/journal.pbio.0000059
By:
- Trotman, Lloyd C;
- Niki, Masaru;
- Dotan, Zohar A;
- Koutcher, Jason A;
- Di Cristofano, Antonio;
- Xiao, Andrew;
- Khoo, Alan S;
- Roy-Burman, Pradip;
- Greenberg, Norman M;
- Dyke, Terry Van;
- Cordon-Cardo, Carlos;
- Pandolfi, Pier Paolo
Publication type:
Article
PTEN Regulation of Local and Long-Range Connections in Mouse Auditory Cortex.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 5, p. 1643, doi. 10.1523/JNEUROSCI.4480-11.2012
By:
- Qiaojie Xiong;
- Oviedo, Hysell V.;
- Trotman, Lloyd C.;
- Zador, Anthony M.
Publication type:
Article

Found: 14