Works by Treff, Nathan

Results: 45

Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 7, p. 901, doi. 10.1038/ejhg.2014.222

By:

Capalbo, Antonio;
Treff, Nathan R;
Cimadomo, Danilo;
Tao, Xin;
Upham, Kathleen;
Ubaldi, Filippo Maria;
Rienzi, Laura;
Scott, Richard T

Publication type:

Article

High-throughput real-time PCR-based genotyping without DNA purification.

Published in:

BMC Research Notes, 2012, v. 5, n. 1, p. 573, doi. 10.1186/1756-0500-5-573

By:

Fedick, Anastasia;
Jing Su;
Jalas, Chaim;
Treff, Nathan R.

Publication type:

Article

Crystal structures of unligated and CN-ligated Glycera dibranchiata monomer ferric hemoglobin components III and IV.

Published in:

Proteins, 2002, v. 49, n. 1, p. 49, doi. 10.1002/prot.10199

By:

Park, Ha-Jeung;
Yang, Cheng;
Treff, Nathan;
Satterlee, James D.;
Kang, ChulHee

Publication type:

Article

Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy.

Published in:

PLoS Genetics, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.pgen.1002161

By:

Treff, Nathan R.;
Jing Su;
Taylor, Deanne;
Scott Jr., Richard T.

Publication type:

Article

Diagnosis of human preimplantation embryo viability.

Published in:

2015

By:

Gardner, David K.;
Meseguer, Marcos;
Rubio, Carmen;
Treff, Nathan R.

Publication type:

journal article

Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy.

Published in:

Molecular Human Reproduction, 2017, v. 23, n. 6, p. 406, doi. 10.1093/molehr/gax018

By:

Nguyen, Alexandra L.;
Marin, Diego;
Anbo Zhou;
Gentilello, Amanda S.;
Smoak, Evan M.;
Zubing Cao;
Fedick, Anastasia;
Yujue Wang;
Taylor, Deanne;
Scott Jr, Richard T.;
Jinchuan Xing;
Treff, Nathan;
Schindler, Karen

Publication type:

Article

Comprehensive chromosome screening and gene expression analysis from the same biopsy in human preimplantation embryos.

Published in:

Molecular Human Reproduction, 2017, v. 23, n. 5, p. 330, doi. 10.1093/molehr/gax014

By:

Marin, Diego;
Yujue Wang;
Xin Tao;
Scott Jr., Richard T.;
Treff, Nathan R.

Publication type:

Article

Expression and characterization of three Aurora kinase C splice variants found in human oocytes.

Published in:

Molecular Human Reproduction, 2015, v. 21, n. 8, p. 633, doi. 10.1093/molehr/gav026

By:

Fellmeth, Jessica E.;
Gordon, Derek;
Robins, Christian E.;
Scott Jr, Richard T.;
Treff, Nathan R.;
Schindler, Karen

Publication type:

Article

Tracking embryo implantation using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation.

Published in:

Molecular Human Reproduction, 2011, v. 17, n. 7, p. 434, doi. 10.1093/molehr/gar016

By:

Treff, Nathan R.;
Tao, Xin;
Su, Jing;
Lonczak, Agnieszka;
Northrop, Lesley E.;
Ruiz, Andrew A.;
Scott, Richard T.

Publication type:

Article

Single-cell whole-genome amplification technique impacts the accuracy of SNP microarray-based genotyping and copy number analyses.

Published in:

Molecular Human Reproduction, 2011, v. 17, n. 6, p. 335, doi. 10.1093/molehr/gaq103

By:

Treff, Nathan R.;
Su, Jing;
Tao, Xin;
Northrop, Lesley E.;
Scott, Richard T.

Publication type:

Article

SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH.

Published in:

Molecular Human Reproduction, 2010, v. 16, n. 8, p. 583, doi. 10.1093/molehr/gaq039

By:

Treff, Nathan R.;
Levy, Brynn;
Su, Jing;
Northrop, Lesley E.;
Tao, Xin;
Scott, Richard T.

Publication type:

Article

Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations.

Published in:

Genes, 2021, v. 12, n. 8, p. 1105, doi. 10.3390/genes12081105

By:

Tellier, Laurent C. A. M.;
Eccles, Jennifer;
Treff, Nathan R.;
Lello, Louis;
Fishel, Simon;
Hsu, Stephen

Publication type:

Article

Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs.

Published in:

Genes, 2020, v. 11, n. 6, p. 648, doi. 10.3390/genes11060648

By:

Treff, Nathan R.;
Eccles, Jennifer;
Marin, Diego;
Messick, Edward;
Lello, Louis;
Gerber, Jessalyn;
Xu, Jia;
Tellier, Laurent C.A.M.

Publication type:

Article

Preimplantation genetic testing for aneuploidy: A review of published blastocyst reanalysis concordance data.

Published in:

Prenatal Diagnosis, 2021, v. 41, n. 5, p. 545, doi. 10.1002/pd.5828

By:

Marin, Diego;
Xu, Jia;
Treff, Nathan R.

Publication type:

Article

Editorial: Causes of Oocyte Aneuploidy and Infertility in Advanced Maternal Age and Emerging Therapeutic Approaches.

Published in:

2021

By:

Bernstein, Lori R.;
Treff, Nathan R.

Publication type:

Editorial

High-resolution PGT-A results in incidental identification of patients with small pathogenic copy number variants.

Published in:

2024

By:

Leahy, Deirdre;
Marin, Diego;
Xu, Jia;
Eccles, Jennifer;
Treff, Nathan R.

Publication type:

Case Study

Mitochondrial DNA content is associated with ploidy status, maternal age, and oocyte maturation methods in mouse blastocysts.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 12, p. 1587, doi. 10.1007/s10815-017-1070-8

By:

Tao, Xin;
Landis, Jessica;
Krisher, Rebecca;
Duncan, Francesca;
Silva, Elena;
Lonczak, Agnieszka;
Scott, Richard;
Zhan, Yiping;
Chu, Tinchun;
Treff, Nathan

Publication type:

Article

Evaluation of comprehensive chromosome screening platforms for the detection of mosaic segmental aneuploidy.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 8, p. 975, doi. 10.1007/s10815-017-0924-4

By:

Goodrich, David;
Xing, Tongji;
Tao, Xin;
Lonczak, Agnieszka;
Zhan, Yiping;
Landis, Jessica;
Zimmerman, Rebekah;
Scott, Richard;
Treff, Nathan

Publication type:

Article

A randomized and blinded comparison of qPCR and NGS-based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism.

Published in:

Journal of Assisted Reproduction & Genetics, 2016, v. 33, n. 11, p. 1473, doi. 10.1007/s10815-016-0784-3

By:

Goodrich, David;
Tao, Xin;
Bohrer, Chelsea;
Lonczak, Agnieszka;
Xing, Tongji;
Zimmerman, Rebekah;
Zhan, Yiping;
Scott Jr, Richard;
Treff, Nathan

Publication type:

Article

SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts.

Published in:

Journal of Assisted Reproduction & Genetics, 2016, v. 33, n. 8, p. 1115, doi. 10.1007/s10815-016-0734-0

By:

Treff, Nathan;
Thompson, Katherine;
Rafizadeh, Michael;
Chow, Michael;
Morrison, Liza;
Tao, Xin;
Garnsey, Heather;
Reda, Christine;
Metzgar, Talia;
Neal, Shelby;
Jalas, Chaim;
Scott, Richard;
Forman, Eric

Publication type:

Article

Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients.

Published in:

Journal of Assisted Reproduction & Genetics, 2016, v. 33, n. 1, p. 67, doi. 10.1007/s10815-015-0606-z

By:

Patounakis, George;
Bergh, Eric;
Forman, Eric;
Tao, Xin;
Lonczak, Agnieszka;
Franasiak, Jason;
Treff, Nathan;
Scott, Richard

Publication type:

Article

Trophectoderm DNA fingerprinting by quantitative real-time PCR successfully distinguishes sibling human embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2014, v. 31, n. 11, p. 1421, doi. 10.1007/s10815-014-0315-z

By:

Scott, Richard;
Su, Jing;
Tao, Xin;
Forman, Eric;
Hong, Kathleen;
Taylor, Deanne;
Treff, Nathan

Publication type:

Article

Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure.

Published in:

Journal of Assisted Reproduction & Genetics, 2014, v. 31, n. 11, p. 1501, doi. 10.1007/s10815-014-0333-x

By:

Franasiak, Jason;
Forman, Eric;
Hong, Kathleen;
Werner, Marie;
Upham, Kathleen;
Treff, Nathan;
Scott, Richard

Publication type:

Article

Improved sensitivity to detect recombination using qPCR for Dyskeratosis Congenita PGD.

Published in:

2014

By:

Gueye, Ndeye-Aicha;
Jalas, Chaim;
Tao, Xin;
Taylor, Deanne;
Scott, Richard;
Treff, Nathan

Publication type:

Report

Lack of association of KATNAL1 gene sequence variants and azoospermia in humans.

Published in:

Journal of Assisted Reproduction & Genetics, 2014, v. 31, n. 8, p. 1065, doi. 10.1007/s10815-014-0269-1

By:

Fedick, Anastasia;
Eckert, Kyle;
Thompson, Katharine;
Forman, Eric;
Devkota, Batsal;
Treff, Nathan;
Taylor, Deanne;
Scott, Richard

Publication type:

Article

Incidental identification of balanced translocation carrier patients through comprehensive chromosome screening of IVF-derived blastocysts.

Published in:

Journal of Assisted Reproduction & Genetics, 2013, v. 30, n. 6, p. 787, doi. 10.1007/s10815-013-0008-z

By:

Treff, Nathan;
Forman, Eric;
Katz-Jaffe, Mandy;
Schoolcraft, William;
Levy, Brynn;
Scott, Richard

Publication type:

Article

Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies.

Published in:

2012

By:

Scott, Richard;
Treff, Nathan;
Stevens, John;
Forman, Eric;
Hong, Kathleen;
Katz-Jaffe, Mandy;
Schoolcraft, William

Publication type:

Report

Methods for comprehensive chromosome screening of oocytes and embryos: capabilities, limitations, and evidence of validity.

Published in:

Journal of Assisted Reproduction & Genetics, 2012, v. 29, n. 5, p. 381, doi. 10.1007/s10815-012-9727-9

By:

Treff, Nathan;
Scott, Richard

Publication type:

Article

Polar body morphology is not predictive of its cell division origin.

Published in:

Journal of Assisted Reproduction & Genetics, 2012, v. 29, n. 2, p. 137, doi. 10.1007/s10815-011-9683-9

By:

Treff, Nathan;
Scott, Richard;
Su, Jing;
Campos, Jessyca;
Stevens, John;
Schoolcraft, William;
Katz-Jaffe, Mandy

Publication type:

Article

Exome sequencing links CEP120 mutation to maternally derived aneuploid conception risk.

Published in:

2020

By:

Tyc, Katarzyna M;
Yakoubi, Warif El;
Bag, Aishee;
Landis, Jessica;
Zhan, Yiping;
Treff, Nathan R;
Scott, Richard T;
Tao, Xin;
Schindler, Karen;
Xing, Jinchuan;
El Yakoubi, Warif

Publication type:

journal article

Levels of trophectoderm mitochondrial DNA do not predict the reproductive potential of sibling embryos.

Published in:

2017

By:

Treff, Nathan R.;
Yiping Zhan;
Xin Tao;
Olcha, Meir;
Han, Michael;
Rajchel, Jessica;
Morrison, Liza;
Morin, Scott J.;
Scott Jr, Richard T.;
Zhan, Yiping;
Tao, Xin;
Scott, Richard T Jr

Publication type:

journal article

Detecting mosaicism in trophectoderm biopsies.

Published in:

Human Reproduction, 2017, v. 32, n. 3, p. 712, doi. 10.1093/humrep/dew346

By:

Sermon, Karen D.;
Spits, Claudia;
Mertzanidou, Afroditi;
Vermeesch, Joris R.;
Fiorentino, Francesco;
Capalbo, Antonio;
Ubaldi, Filippo;
Rienzi, Laura;
Scott, Richard;
Treff, Nathan

Publication type:

Article

Detecting mosaicism in trophectoderm biopsies: current challenges and future possibilities.

Published in:

2017

By:

Capalbo, Antonio;
Ubaldi, Filippo Maria;
Rienzi, Laura;
Scott, Richard;
Treff, Nathan

Publication type:

journal article

Reply: Detecting mosaicism in trophectoderm biopsies.

Published in:

2017

By:

Capalbo, Antonio;
Ubaldi, Filippo;
Rienzi, Laura;
Scott, Richard;
Treff, Nathan

Publication type:

Letter

Embryonic aneuploidy does not differ among genetic ancestry according to continental origin as determined by ancestry informative markers.

Published in:

2016

By:

Franasiak, Jason M.;
Olcha, Meir;
Shastri, Shefali;
Molinaro, Thomas A.;
Congdon, Haley;
Treff, Nathan R.;
Scott Jr., Richard T.;
Scott, Richard T Jr

Publication type:

journal article

Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest.

Published in:

2016

By:

Kort, Daniel H.;
Chia, Gloryn;
Treff, Nathan R.;
Tanaka, Akemi J.;
Tongji Xing;
Bauer Vensand, Lauren;
Micucci, Stephanie;
Prosser, Robert;
Lobo, Roger A.;
Sauer, Mark V.;
Egli, Dieter;
Xing, Tongji;
Vensand, Lauren Bauer

Publication type:

journal article

The severity of meiotic aneuploidy is associated with altered morphokinetic variables of mouse oocyte maturation.

Published in:

Human Reproduction Open, 2024, v. 2024, n. 2, p. 1, doi. 10.1093/hropen/hoae023

By:

Zhu, Yiru;
Kratka, Catherine R;
Pea, Jeffrey;
Lee, Hoi Chang;
Kratka, Caroline E;
Xu, Jia;
Marin, Diego;
Treff, Nathan R;
Duncan, Francesca E

Publication type:

Article

Investigating the impact of the timing of blastulation on implantation: management of embryo-endometrial synchrony improves outcomes.

Published in:

Human Reproduction Open, 2018, v. 2018, n. 4, p. 1, doi. 10.1093/hropen/hoy022

By:

Franasiak, Jason M;
Forman, Eric J;
Patounakis, George;
Hong, Kathleen H;
Werner, Marie D;
Upham, Kathleen M;
Treff, Nathan R;
Scott, Richard T

Publication type:

Article

Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction.

Published in:

Frontiers in Endocrinology, 2019, v. 10, p. 1, doi. 10.3389/fendo.2019.00845

By:

Treff, Nathan R.;
Eccles, Jennifer;
Lello, Lou;
Bechor, Elan;
Hsu, Jeffrey;
Plunkett, Kathryn;
Zimmerman, Raymond;
Rana, Bhavini;
Samoilenko, Artem;
Hsu, Steven;
Tellier, Laurent C. A. M.

Publication type:

Article

High-Throughput Carrier Screening Using TaqMan Allelic Discrimination.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059722

By:

Fedick, Anastasia;
Su, Jing;
Jalas, Chaim;
Northrop, Lesley;
Devkota, Batsal;
Ekstein, Josef;
Treff, Nathan R.

Publication type:

Article

Differentiation of Embryonic Stem Cells Conditionally Expressing Neurogenin 3.

Published in:

Stem Cells, 2006, v. 24, n. 11, p. 2529, doi. 10.1634/stemcells.2006-0082

By:

Treff, Nathan R.;
Vincent, Robert K.;
Budde, Melisa L.;
Browning, Victoria L.;
Magliocca, Joseph F.;
Kapur, Vivek;
Odorico, Jon S.

Publication type:

Article

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants.

Published in:

Nature, 2013, v. 493, n. 7434, p. 632, doi. 10.1038/nature11800

By:

Paull, Daniel;
Emmanuele, Valentina;
Weiss, Keren A.;
Treff, Nathan;
Stewart, Latoya;
Hua, Haiqing;
Zimmer, Matthew;
Kahler, David J.;
Goland, Robin S.;
Noggle, Scott A.;
Prosser, Robert;
Hirano, Michio;
Sauer, Mark V.;
Egli, Dieter

Publication type:

Article

Carrier frequencies of eleven mutations in eight genes associated with primary ciliary dyskinesia in the Ashkenazi Jewish population.

Published in:

Molecular Genetics & Genomic Medicine, 2015, v. 3, n. 2, p. 137, doi. 10.1002/mgg3.124

By:

Fedick, Anastasia M.;
Jalas, Chaim;
Treff, Nathan R.;
Knowles, Michael R.;
Zariwala, Maimoona A.

Publication type:

Article

Human KIT ligand promoter is positively regulated by HMGA1 in breast and ovarian cancer cells.

Published in:

Oncogene, 2004, v. 23, n. 52, p. 8557, doi. 10.1038/sj.onc.1207926

By:

Treff, Nathan R;
Dement, Gregory A;
Adair, Jennifer E;
Britt, Rachel L;
Nie, Rong;
Shima, James E;
Taylor, Wayne E;
Reeves, Raymond

Publication type:

Article

High-mobility group A1a protein regulates Ras/ERK signaling in MCF-7 human breast cancer cells.

Published in:

Oncogene, 2004, v. 23, n. 3, p. 777, doi. 10.1038/sj.onc.1207167

By:

Treff, Nathan R.;
Pouchnik, Derek;
Dement, Gregory A.;
Britt, Rachel L.;
Reeves, Raymond

Publication type:

Article