Works by Trautmann, Sandra

Results: 32

Characterization of the Sphingolipidome of the Peri-Infarct Tissue during Hemorrhagic Transformation in a Mouse Model of Cerebral Ischemia.

Published in:

Journal of Integrative Neuroscience, 2022, v. 21, n. 6, p. 1, doi. 10.31083/j.jin2106161

By:

Lucaciu, Alexandra;
Trautmann, Sandra;
Thomas, Dominique;
Lachner, Karsten;
Brunkhorst, Robert;
Subburayalu, Julien

Publication type:

Article

Machine learning and biological validation identify sphingolipids as potential mediators of paclitaxel-induced neuropathy in cancer patients.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91941

By:

Lötsch, Jörn;
Gasimli, Khayal;
Malkusch, Sebastian;
Hahnefeld, Lisa;
Angioni, Carlo;
Schreiber, Yannick;
Trautmann, Sandra;
Wedel, Saskia;
Thomas, Dominique;
Bouzas, Nerea Ferreiros;
Brandts, Christian H.;
Schnappauf, Benjamin;
Solbach, Christine;
Geisslinger, Gerd;
Sisignano, Marco

Publication type:

Article

C6 Ceramide (d18:1/6:0) as a Novel Treatment of Cutaneous T Cell Lymphoma.

Published in:

Cancers, 2021, v. 13, n. 2, p. 270, doi. 10.3390/cancers13020270

By:

Wilhelm, Raphael;
Eckes, Timon;
Imre, Gergely;
Kippenberger, Stefan;
Meissner, Markus;
Thomas, Dominique;
Trautmann, Sandra;
Merlio, Jean-Philippe;
Chevret, Edith;
Kaufmann, Roland;
Pfeilschifter, Josef;
Koch, Alexander;
Jäger, Manuel

Publication type:

Article

Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation.

Published in:

Cancers, 2020, v. 12, n. 7, p. 1753, doi. 10.3390/cancers12071753

By:

El-Hindi, Khadija;
Brachtendorf, Sebastian;
Hartel, Jennifer Christina;
Oertel, Stephanie;
Birod, Kerstin;
Trautmann, Sandra;
Thomas, Dominique;
Ulshöfer, Thomas;
Weigert, Andreas;
Utermöhlen, Olaf;
Krönke, Martin;
Grösch, Sabine

Publication type:

Article

Sphingolipid and Endocannabinoid Profiles in Adult Attention Deficit Hyperactivity Disorder.

Published in:

Biomedicines, 2021, v. 9, n. 9, p. 1173, doi. 10.3390/biomedicines9091173

By:

Brunkhorst-Kanaan, Nathalie;
Trautmann, Sandra;
Schreiber, Yannick;
Thomas, Dominique;
Kittel-Schneider, Sarah;
Gurke, Robert;
Geisslinger, Gerd;
Reif, Andreas;
Tegeder, Irmgard

Publication type:

Article

UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65182-y

By:

Schömel, Nina;
Gruber, Lisa;
Alexopoulos, Stephanie J.;
Trautmann, Sandra;
Olzomer, Ellen M.;
Byrne, Frances L.;
Hoehn, Kyle L.;
Gurke, Robert;
Thomas, Dominique;
Ferreirós, Nerea;
Geisslinger, Gerd;
Wegner, Marthe-Susanna

Publication type:

Article

In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64382-w

By:

Blum, Leonard;
Gul, Sheraz;
Ulshöfer, Thomas;
Henke, Marina;
Krieg, Reimar;
Berneburg, Isabell;
Thomas, Dominique;
Trautmann, Sandra;
Kurz, Jennifer;
Geyer, Joachim;
Geisslinger, Gerd;
Becker, Katja;
Parnham, Michael J.;
Schiffmann, Susanne

Publication type:

Article

The atypical sphingosine 1‐phosphate variant, d16:1 S1P, mediates CTGF induction via S1P2 activation in renal cell carcinoma.

Published in:

FEBS Journal, 2022, v. 289, n. 18, p. 5670, doi. 10.1111/febs.16446

By:

Glueck, Melanie;
Koch, Alexander;
Brunkhorst, Robert;
Ferreiros Bouzas, Nerea;
Trautmann, Sandra;
Schaefer, Liliana;
Pfeilschifter, Waltraud;
Pfeilschifter, Josef;
Vutukuri, Rajkumar

Publication type:

Article

High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease.

Published in:

Movement Disorders, 2020, v. 35, n. 10, p. 1822, doi. 10.1002/mds.28186

By:

Klatt‐Schreiner, Katharina;
Valek, Lucie;
Kang, Jun‐Suk;
Khlebtovsky, Alexander;
Trautmann, Sandra;
Hahnefeld, Lisa;
Schreiber, Yannick;
Gurke, Robert;
Thomas, Dominique;
Wilken‐Schmitz, Annett;
Wicker, Sabine;
Auburger, Georg;
Geisslinger, Gerd;
Lötsch, Jörn;
Pfeilschifter, Waltraud;
Djaldetti, Ruth;
Tegeder, Irmgard

Publication type:

Article

Prodromal sensory neuropathy in Pink1−/−SNCAA53T double mutant Parkinson mice.

Published in:

Neuropathology & Applied Neurobiology, 2021, v. 47, n. 7, p. 1060, doi. 10.1111/nan.12734

By:

Valek, Lucie;
Tran, Bao;
Wilken‐Schmitz, Annett;
Trautmann, Sandra;
Heidler, Juliana;
Schmid, Tobias;
Brüne, Bernhard;
Thomas, Dominique;
Deller, Thomas;
Geisslinger, Gerd;
Auburger, Georg;
Tegeder, Irmgard

Publication type:

Article

Increased Fat Taste Preference in Progranulin-Deficient Mice.

Published in:

Nutrients, 2021, v. 13, n. 11, p. 4125, doi. 10.3390/nu13114125

By:

Schumann, Lana;
Wilken-Schmitz, Annett;
Trautmann, Sandra;
Vogel, Alexandra;
Schreiber, Yannick;
Hahnefeld, Lisa;
Gurke, Robert;
Geisslinger, Gerd;
Tegeder, Irmgard

Publication type:

Article

A role for plasma membrane Ca2+ ATPases in regulation of cellular Ca2+ homeostasis by sphingosine kinase-1.

Published in:

Pflügers Archiv: European Journal of Physiology, 2024, v. 476, n. 12, p. 1895, doi. 10.1007/s00424-024-03027-7

By:

Volk, Luisa Michelle;
Bruun, Jan-Erik;
Trautmann, Sandra;
Thomas, Dominique;
Schwalm, Stephanie;
Pfeilschifter, Josef;
zu Heringdorf, Dagmar Meyer

Publication type:

Article

Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells.

Published in:

Cellular & Molecular Life Sciences, 2021, v. 78, n. 21/22, p. 7025, doi. 10.1007/s00018-021-03958-9

By:

Wegner, Marthe-Susanna;
Schömel, Nina;
Olzomer, Ellen M.;
Trautmann, Sandra;
Olesch, Catherine;
Byrne, Frances L.;
Brüne, Bernhard;
Gurke, Robert;
Ferreirós, Nerea;
Weigert, Andreas;
Geisslinger, Gerd;
Hoehn, Kyle L.

Publication type:

Article

UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells.

Published in:

Cellular & Molecular Life Sciences, 2018, v. 75, n. 18, p. 3393, doi. 10.1007/s00018-018-2799-7

By:

Wegner, Marthe-Susanna;
Schömel, Nina;
Gruber, Lisa;
Örtel, Stephanie Beatrice;
Kjellberg, Matti Aleksi;
Mattjus, Peter;
Kurz, Jennifer;
Trautmann, Sandra;
Peng, Bing;
Wegner, Martin;
Kaulich, Manuel;
Ahrends, Robert;
Geisslinger, Gerd;
Grösch, Sabine

Publication type:

Article

Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.

Published in:

Cellular & Molecular Life Sciences, 2017, v. 74, n. 16, p. 3039, doi. 10.1007/s00018-017-2518-9

By:

Geisslinger, Gerd;
Oertel, Stephanie;
Scholich, Klaus;
Thomas, Dominique;
Schmetzer, Julia;
Trautmann, Sandra;
Wegner, Marthe-Susanna;
Tegeder, Irmgard;
Grösch, Sabine;
Weigert, Andreas;
Brüne, Bernhard;
Radeke, Heinfried;
Filmann, Natalie

Publication type:

Article

Endothelial Sphingosine-1-Phosphate Receptor 4 Regulates Blood-Brain Barrier Permeability and Promotes a Homeostatic Endothelial Phenotype.

Published in:

Journal of Neuroscience, 2022, v. 42, n. 10, p. 1908, doi. 10.1523/JNEUROSCI.0188-21.2021

By:

Hansen, Lena;
Lohfink, Niklas;
Vutukuri, Rajkumar;
Kestner, Roxane-Isabelle;
Trautmann, Sandra;
Hecht, Max;
Wagner, Pia Viktoria;
Spitzer, Daniel;
Khel, Maryam Ibrahim;
Macas, Jadranka;
Ferreirós, Nerea;
Gurke, Robert;
Günther, Stefan;
Pfeilschifter, Waltraud;
Devraj, Kavi

Publication type:

Article

Influence of air-polishing devices and abrasives on root dentin--An in vitro confocal laser scanning microscope study.

Published in:

Quintessence International, 2010, v. 41, n. 7, p. e141

By:

Pelka, Matthias;
Trautmann, Sandra;
Petschelt, Anselm;
Lohbauer, Ullrich

Publication type:

Article

The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in the AppNL–G–F Model of Alzheimer's Disease.

Published in:

Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.876826

By:

Nieraad, Hendrik;
de Bruin, Natasja;
Arne, Olga;
Hofmann, Martine C. J.;
Pannwitz, Nina;
Resch, Eduard;
Luckhardt, Sonja;
Schneider, Ann-Kathrin;
Trautmann, Sandra;
Schreiber, Yannick;
Gurke, Robert;
Parnham, Michael J.;
Till, Uwe;
Geisslinger, Gerd

Publication type:

Article

Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8508, doi. 10.3390/ijms24108508

By:

Standoli, Sara;
Rapino, Cinzia;
Di Meo, Camilla;
Rudowski, Agnes;
Kämpfer-Kolb, Nicole;
Volk, Luisa Michelle;
Thomas, Dominique;
Trautmann, Sandra;
Schreiber, Yannick;
Meyer zu Heringdorf, Dagmar;
Maccarrone, Mauro

Publication type:

Article

Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5882, doi. 10.3390/ijms23115882

By:

Hafizi, Redona;
Imeri, Faik;
Stepanovska Tanturovska, Bisera;
Manaila, Roxana;
Schwalm, Stephanie;
Trautmann, Sandra;
Wenger, Roland H.;
Pfeilschifter, Josef;
Huwiler, Andrea

Publication type:

Article

T-Cell-Specific CerS4 Depletion Prolonged Inflammation and Enhanced Tumor Burden in the AOM/DSS-Induced CAC Model.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1866, doi. 10.3390/ijms23031866

By:

El-Hindi, Khadija;
Brachtendorf, Sebastian;
Hartel, Jennifer Christina;
Oertel, Stephanie;
Birod, Kerstin;
Merz, Nadine;
Trautmann, Sandra;
Thomas, Dominique;
Weigert, Andreas;
Schäufele, Tim J.;
Scholich, Klaus;
Schiffmann, Susanne;
Ulshöfer, Thomas;
Utermöhlen, Olaf;
Grösch, Sabine

Publication type:

Article

Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10617, doi. 10.3390/ijms221910617

By:

Spohner, Anna Katharina;
Jakobi, Katja;
Trautmann, Sandra;
Thomas, Dominique;
Schumacher, Fabian;
Kleuser, Burkhard;
Lütjohann, Dieter;
El-Hindi, Khadija;
Grösch, Sabine;
Pfeilschifter, Josef;
Saba, Julie D.;
Meyer zu Heringdorf, Dagmar

Publication type:

Article

A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6242, doi. 10.3390/ijms21176242

By:

Lucaciu, Alexandra;
Kuhn, Hannah;
Trautmann, Sandra;
Ferreirós, Nerea;
Steinmetz, Helmuth;
Pfeilschifter, Josef;
Brunkhorst, Robert;
Pfeilschifter, Waltraud;
Subburayalu, Julien;
Vutukuri, Rajkumar

Publication type:

Article

Preanalytical Biases in the Measurement of Human Blood Sphingolipids.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 5, p. 1390, doi. 10.3390/ijms19051390

By:

Brunkhorst, Robert;
Pfeilschifter, Waltraud;
Patyna, Sammy;
Büttner, Stefan;
Eckes, Timon;
Trautmann, Sandra;
Thomas, Dominique;
Pfeilschifter, Josef;
Koch, Alexander

Publication type:

Article

Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1532, doi. 10.3390/ijms18071532

By:

Koch, Alexander;
Grammatikos, Georgios;
Trautmann, Sandra;
Schreiber, Yannick;
Thomas, Dominique;
Bruns, Franziska;
Pfeilschifter, Josef;
Badenhoop, Klaus;
Penna-Martinez, Marissa

Publication type:

Article

Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01242

By:

Schmidt, Katrin G.;
Juan, Martina Herrero San;
Trautmann, Sandra;
Berninger, Lucija;
Schwiebs, Anja;
Ottenlinger, Florian M.;
Thomas, Dominique;
Zaucke, Frank;
Pfeilschifter, Josef M.;
Radeke, Heinfried H.

Publication type:

Article

The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 971, doi. 10.3390/jcm8070971

By:

Bazarganipour, Sarah;
Hausmann, Johannes;
Oertel, Stephanie;
El-Hindi, Khadija;
Brachtendorf, Sebastian;
Blumenstein, Irina;
Kubesch, Alica;
Sprinzl, Kathrin;
Birod, Kerstin;
Hahnefeld, Lisa;
Trautmann, Sandra;
Thomas, Dominique;
Herrmann, Eva;
Geisslinger, Gerd;
Schiffmann, Susanne;
Grösch, Sabine

Publication type:

Article

The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 7, p. 971, doi. 10.3390/jcm8070971

By:

Bazarganipour, Sarah;
Hausmann, Johannes;
Oertel, Stephanie;
El-Hindi, Khadija;
Brachtendorf, Sebastian;
Blumenstein, Irina;
Kubesch, Alica;
Sprinzl, Kathrin;
Birod, Kerstin;
Hahnefeld, Lisa;
Trautmann, Sandra;
Thomas, Dominique;
Herrmann, Eva;
Geisslinger, Gerd;
Schiffmann, Susanne;
Grösch, Sabine

Publication type:

Article

Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2201, doi. 10.3390/cells9102201

By:

Blankenbach, Kira Vanessa;
Claas, Ralf Frederik;
Aster, Natalie Judith;
Spohner, Anna Katharina;
Trautmann, Sandra;
Ferreirós, Nerea;
Black, Justin L.;
Tesmer, John J. G.;
Offermanns, Stefan;
Wieland, Thomas;
Meyer zu Heringdorf, Dagmar

Publication type:

Article

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death.

Published in:

Autophagy, 2021, v. 17, n. 11, p. 3424, doi. 10.1080/15548627.2021.1874208

By:

Meyer, Nina;
Henkel, Lisa;
Linder, Benedikt;
Zielke, Svenja;
Tascher, Georg;
Trautmann, Sandra;
Geisslinger, Gerd;
Münch, Christian;
Fulda, Simone;
Tegeder, Irmgard;
Kögel, Donat

Publication type:

Article

Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage.

Published in:

European Journal of Immunology, 2016, v. 46, n. 2, p. 440, doi. 10.1002/eji.201545910

By:

Schminke, Boris;
Trautmann, Sandra;
Mai, Burkhard;
Miosge, Nicolai;
Blaschke, Sabine

Publication type:

Article

S1P d20:1, an endogenous modulator of S1P d18:1/S1P2‐dependent signaling.

Published in:

FASEB Journal, 2020, v. 34, n. 3, p. 3932, doi. 10.1096/fj.201902391R

By:

Vutukuri, Rajkumar;
Koch, Alexander;
Trautmann, Sandra;
Schreiber, Yannick;
Thomas, Dominique;
Mayser, Franziska;
Meyer zu Heringdorf, Dagmar;
Pfeilschifter, Josef;
Pfeilschifter, Waltraud;
Brunkhorst, Robert

Publication type:

Article

Works by Trautmann, Sandra

Characterization of the Sphingolipidome of the Peri-Infarct Tissue during Hemorrhagic Transformation in a Mouse Model of Cerebral Ischemia.

Machine learning and biological validation identify sphingolipids as potential mediators of paclitaxel-induced neuropathy in cancer patients.

C6 Ceramide (d18:1/6:0) as a Novel Treatment of Cutaneous T Cell Lymphoma.

Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation.

Sphingolipid and Endocannabinoid Profiles in Adult Attention Deficit Hyperactivity Disorder.

UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells.

In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o.

The atypical sphingosine 1‐phosphate variant, d16:1 S1P, mediates CTGF induction via S1P2 activation in renal cell carcinoma.

High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease.

Prodromal sensory neuropathy in Pink1<sup>−/−</sup>SNCA<sup>A53T</sup> double mutant Parkinson mice.

Increased Fat Taste Preference in Progranulin-Deficient Mice.

A role for plasma membrane Ca<sup>2+</sup> ATPases in regulation of cellular Ca<sup>2+</sup> homeostasis by sphingosine kinase-1.

Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells.

UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells.

Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.

Endothelial Sphingosine-1-Phosphate Receptor 4 Regulates Blood-Brain Barrier Permeability and Promotes a Homeostatic Endothelial Phenotype.

Influence of air-polishing devices and abrasives on root dentin--An in vitro confocal laser scanning microscope study.

The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in the App<sup>NL–G–F</sup> Model of Alzheimer's Disease.

Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells.

Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells.

T-Cell-Specific CerS4 Depletion Prolonged Inflammation and Enhanced Tumor Burden in the AOM/DSS-Induced CAC Model.

Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile.

A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke.

Preanalytical Biases in the Measurement of Human Blood Sphingolipids.

Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients.

Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study.

The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.

The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.

Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1.

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death.

Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage.

S1P d20:1, an endogenous modulator of S1P d18:1/S1P<sub>2</sub>‐dependent signaling.