Works by Trapp, Bruce D.

Results: 95

BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54430-8

By:

Gruber, Ross C.;
Wirak, Gregory S.;
Blazier, Anna S.;
Lee, Lan;
Dufault, Michael R.;
Hagan, Nellwyn;
Chretien, Nathalie;
LaMorte, Michael;
Hammond, Timothy R.;
Cheong, Agnes;
Ryan, Sean K.;
Macklin, Andrew;
Zhang, Mindy;
Pande, Nilesh;
Havari, Evis;
Turner, Timothy J.;
Chomyk, Anthony;
Christie, Emilie;
Trapp, Bruce D.;
Ofengeim, Dimitry

Publication type:

Article

Hippocampal Neurogenesis and Neural Circuit Formation in a Cuprizone-Induced Multiple Sclerosis Mouse Model.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 2, p. 447, doi. 10.1523/JNEUROSCI.0866-19.2019

By:

Hai Zhang;
Yeonghwan Kim;
Eun Jeoung Ro;
Ho, Cindy;
Daehoon Lee;
Trapp, Bruce D.;
Hoonkyo Suh

Publication type:

Article

NEURODEGENERATION: THE PATHOLOGIC EVIDENCE.

Published in:

Johns Hopkins Advanced Studies in Medicine, 2009, v. 9, n. 2, p. 37

By:

Trapp, Bruce D.

Publication type:

Article

P0 Protein Is Required for and Can Induce Formation of Schmidt-Lantermann Incisures in Myelin Internodes.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 28, p. 7068, doi. 10.1523/JNEUROSCI.0771-08.2008

By:

Xinghua Yin;
Kidd, Grahame J.;
Nave, Klaus-Amin;
Trapp, Bruce D.

Publication type:

Article

Dysmyelinated Lower Motor Neurons Retract and Regenerate Dysfunctional Synaptic Terminals.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 15, p. 3890, doi. 10.1523/JNEUROSCI.4617-03.2004

By:

Xinghua Yin;
Kidd, Grahame J.;
Pioro, Erik P.;
McDonough, Jennifer;
Dutta, Ranjan;
Feltri, M. Laura;
Wrabetz, Lawrence;
Messing, Albee;
Wyatt, Ryan M.;
Balice-Gordon, Rita J.;
Trapp, Bruce D.

Publication type:

Article

Oligodendrocytes but not astrocytes express apolipoprotein E after injury of rat optic nerve.

Published in:

Glia (0894-1491), 1989, v. 2, n. 3, p. 170, doi. 10.1002/glia.440020306

By:

Stoll, Guido;
Mueller, Hans Werner;
Trapp, Bruce D.;
Griffin, John W.

Publication type:

Article

Lessons from Jack Griffin and the 'pathogenesis of peripheral nerve disease'.

Published in:

Journal of the Peripheral Nervous System, 2012, v. 17, p. 20, doi. 10.1111/j.1529-8027.2012.00426.x

By:

Trapp, Bruce D.

Publication type:

Article

Extensive Cortical Demyelination In Multiple Sclerosis Brains.

Published in:

Acta Neurologica Scandinavica, 2001, v. 103, n. 5, p. 327

By:

Bø, Lars;
Nyland, Harald;
Vedeler, Christian;
Trapp, Bruce D.;
Mörk, Sverre

Publication type:

Article

Intracortical Multiple Sclerosis Lesions Are Not Associated With T Lymphocyte Infiltration.

Published in:

Acta Neurologica Scandinavica, 2001, v. 103, n. 5, p. 327

By:

Bø, Lars;
Nyland, Harald;
Vedeler, Christian;
Trapp, Bruce D.;
Mørk, Sverre J.

Publication type:

Article

Myelin-Associated Glycoprotein Location and Potential Functionsa.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 605, n. 1, p. 29, doi. 10.1111/j.1749-6632.1990.tb42378.x

By:

TRAPP, BRUCE D.

Publication type:

Article

Alterations in CA1 hippocampal synapses in a mouse model of fragile X syndrome.

Published in:

Glia (0894-1491), 2018, v. 66, n. 4, p. 789, doi. 10.1002/glia.23284

By:

Jawaid, Safdar;
Kidd, Grahame J.;
Wang, Jing;
Swetlik, Carrie;
Dutta, Ranjan;
Trapp, Bruce D.

Publication type:

Article

BACE1 regulates the proliferation and cellular functions of Schwann cells.

Published in:

Glia (0894-1491), 2017, v. 65, n. 5, p. 712, doi. 10.1002/glia.23122

By:

Hu, Xiangyou;
Hou, Hailong;
Bastian, Chinthasagar;
He, Wanxia;
Qiu, Shupeng;
Ge, Yingying;
Yin, Xinhua;
Kidd, Grahame J.;
Brunet, Sylvain;
Trapp, Bruce D.;
Baltan, Selva;
Yan, Riqiang

Publication type:

Article

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination.

Published in:

Glia (0894-1491), 2015, v. 63, n. 11, p. 2106, doi. 10.1002/glia.22880

By:

Puntambekar, Shweta S.;
Hinton, David R.;
Yin, Xinghua;
Savarin, Carine;
Bergmann, Cornelia C.;
Trapp, Bruce D.;
Stohlman, Stephen A.

Publication type:

Article

Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin.

Published in:

Glia (0894-1491), 2015, v. 63, n. 1, p. 66, doi. 10.1002/glia.22733

By:

Yin, Xinghua;
Kiryu‐Seo, Sumiko;
Kidd, Grahame J.;
Feltri, M. Laura;
Wrabetz, Lawrence;
Trapp, Bruce D.

Publication type:

Article

NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells.

Published in:

Glia (0894-1491), 2007, v. 55, n. 10, p. 1001, doi. 10.1002/glia.20519

By:

Baracskay, Karen L.;
Kidd, Grahame J.;
Miller, Robert H.;
Trapp, Bruce D.

Publication type:

Article

Evidence for synaptic stripping by cortical microglia.

Published in:

Glia (0894-1491), 2007, v. 55, n. 4, p. 360, doi. 10.1002/glia.20462

By:

Trapp, Bruce D.;
Wujek, Jerome R.;
Criste, Gerson A.;
Jalabi, Walid;
Yin, Xinghua;
Kidd, Grahame J.;
Stohlman, Stephen;
Ransohoff, Richard

Publication type:

Article

A dual tyrosine‐leucine motif mediates myelin protein P0 targeting in MDCK cells.

Published in:

Glia (0894-1491), 2006, v. 54, n. 2, p. 135, doi. 10.1002/glia.20366

By:

Grahame J. Kidd;
Vijay K. Yadav;
Ping Huang;
Stacey L. Brand;
Seng Hui Low;
Thomas Weimbs;
Bruce D. Trapp

Publication type:

Article

IV tubulin is selectively expressed by oligodendrocytes in the central nervous system.

Published in:

Glia (0894-1491), 2005, v. 50, n. 3, p. 212, doi. 10.1002/glia.20175

By:

Nobuo Terada;
Grahame J. Kidd;
Mike Kinter;
Carl Bjartmar;
Kim Moran-Jones;
Bruce D. Trapp

Publication type:

Article

The 36K protein of zebrafish CNS myelin is a short-chain dehydrogenase.

Published in:

Glia (0894-1491), 2004, v. 45, n. 4, p. 378, doi. 10.1002/glia.10338

By:

Jacqueline K. Morris;
Belinda B. Willard;
Xinghua Yin;
Gunnar Jeserich;
Michael Kinter;
Bruce D. Trapp

Publication type:

Article

Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts.

Published in:

Glia (0894-1491), 2003, v. 41, n. 3, p. 276, doi. 10.1002/glia.10191

By:

Forsberg-Nilsson, Karin;
Erlandsson, Anna;
Zhang, Xiao-Qun;
Ueda, Hideho;
Svensson, Kristian;
Nistér, Monica;
Trapp, Bruce D.;
Peterson, Alan C.;
Westermark, Bengt

Publication type:

Article

The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to β1 integrin, CD81, and Tspan-2.

Published in:

Glia (0894-1491), 2002, v. 40, n. 3, p. 350, doi. 10.1002/glia.10134

By:

Terada, Nobuo;
Baracskay, Karen;
Kinter, Mike;
Melrose, Shona;
Brophy, Peter J.;
Boucheix, Claude;
Bjartmar, Carl;
Kidd, Grahame;
Trapp, Bruce D.

Publication type:

Article

Evolution of a neuroprotective function of central nervous system myelin.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 3, p. 469, doi. 10.1083/jcb.200509174

By:

Yin, Xinghua;
Baek, Rena C.;
Kirschner, Daniel A.;
Peterson, Alan;
Fujii, Yasuhisa;
Nave, Klaus-Armin;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Neuroprotection by Preconditioning in Mice is Dependent on MyD88-Mediated CXCL10 Expression in Endothelial Cells.

Published in:

ASN Neuro, 2023, p. 1, doi. 10.1177/17590914221146365

By:

Chen, Zhihong;
Hu, Weiwei;
Mendez, Mynor J.;
Gossman, Zachary C.;
Chomyk, Anthony;
Boylan, Brendan T.;
Kidd, Grahame J.;
Phares, Timothy W.;
Bergmann, Cornelia C.;
Trapp, Bruce D.

Publication type:

Article

Neuroprotection by Preconditioning in Mice is Dependent on MyD88-Mediated CXCL10 Expression in Endothelial Cells.

Published in:

ASN Neuro, 2023, v. 15, p. 1, doi. 10.1177/17590914221146365

By:

Chen, Zhihong;
Hu, Weiwei;
Mendez, Mynor J.;
Gossman, Zachary C.;
Chomyk, Anthony;
Boylan, Brendan T.;
Kidd, Grahame J.;
Phares, Timothy W.;
Bergmann, Cornelia C.;
Trapp, Bruce D.

Publication type:

Article

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 34, p. 11706, doi. 10.1523/JNEUROSCI.0730-12.2012

By:

Zhihong Chen;
Jalabi, Walid;
Shpargel, Karl B.;
Farabaugh, Kenneth T.;
Dutta, Ranjan;
Xinghua Yin;
Kidd, Grahame J.;
Bergmann, Cornelia C.;
Stohlman, Stephen A.;
Trapp, Bruce D.

Publication type:

Article

Myelination and Axonal Electrical Activity Modulate the Distribution and Motility of Mitochondria at CNS Nodes of Ranvier.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 20, p. 7249, doi. 10.1523/JNEUROSCI.0095-11.2011

By:

Ohno, Nobuhiko;
Kidd, Grahame J.;
Mahad, Don;
Kiryu-Seo, Sumiko;
Avishai, Amir;
Komuro, Hitoshi;
Trapp, Bruce D.

Publication type:

Article

Demyelination Increases Axonal Stationary Mitochondrial Size and the Speed of Axonal Mitochondrial Transport.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 19, p. 6658, doi. 10.1523/JNEUROSCI.5265-09.2010

By:

Sumiko Kiryu-Seo;
Nobuhiko Ohno;
Kidd, Grahame J.;
Komuro, Hitoshi;
Trapp, Bruce D.

Publication type:

Article

β4 Tubulin Identifies a Primitive Cell Source for Oligodendrocytes in the Mammalian Brain.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 24, p. 7649, doi. 10.1523/JNEUROSCI.1027-09.2009

By:

Chuanshen Wu;
Chang, Ansi;
Smith, Maria C.;
Won, Roy;
Xinghua Yin;
Staugaitis, Susan M.;
Agamanolis, Dimitri;
Kidd, Grahame J.;
Miller, Robert H.;
Trapp, Bruce D.

Publication type:

Article

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.

Published in:

Annals of Neurology, 2006, v. 59, n. 3, p. 478

By:

Ranjan Dutta;
Jennifer McDonough;
Xinghua Yin;
John Peterson;
Ansi Chang;
Thalia Torres;
Tatyana Gudz;
Wendy B. Macklin;
David A. Lewis;
Robert J. Fox;
Richard Rudick;
Karoly Mirnics;
Bruce D. Trapp

Publication type:

Article

Pathogenesis of multiple sclerosis: The eyes only see what the mind is prepared to comprehend.

Published in:

Annals of Neurology, 2004, v. 55, n. 4, p. 455

By:

Bruce D Trapp

Publication type:

Article

N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve.

Published in:

2002

By:

Bjartmar, Carl;
Battistuta, Jan;
Terada, Nobuo;
Dupree, Erica;
Trapp, Bruce D.

Publication type:

journal article

N-acetylaspartate: usefulness as an indicator of viable neuronal tissue.

Published in:

2001

By:

Arnold, Douglas L.;
De Stefano, Nicola;
Matthews, Paul M.;
Trapp, Bruce D.;
Arnold, D L;
de Stefano, N;
Matthews, P M;
Trapp, B D

Publication type:

commentary

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.

Published in:

2001

By:

Peterson, John W.;
Bö, Lars;
Mörk, Sverre;
Chang, Ansi;
Trapp, Bruce D.;
Peterson, J W;
Bö, L;
Mörk, S;
Chang, A;
Trapp, B D

Publication type:

journal article

Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients.

Published in:

Annals of Neurology, 2000, v. 48, n. 6, p. 893, doi. 10.1002/1531-8249(200012)48:6<893::AID-ANA10>3.0.CO;2-B

By:

Bjartmar, Carl;
Kidd, Grahame;
Mörk, Sverre;
Rudick, Richard;
Trapp, Bruce D.

Publication type:

Article

Leukodystrophy in patients with ovarian dysgenesis.

Published in:

Annals of Neurology, 1997, v. 41, n. 5, p. 654, doi. 10.1002/ana.410410515

By:

Schiffmann, Raphael;
Tedeschi, Gioacchino;
Kinkel, R. Philip;
Trapp, Bruce D.;
Frank, Joseph A.;
Kaneski, Christine R.;
Brady, Roscoe O.;
Barton, Norman W.;
Nelson, Lawrence;
Yanovski, Jack A.

Publication type:

Article

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains.

Published in:

Annals of Neurology, 1994, v. 36, n. 5, p. 778, doi. 10.1002/ana.410360515

By:

Bö, Lars;
Dawson, Ted M.;
Wesselingh, Steven;
Möurk, Sverre;
Choi, Steven;
Kong, Pei Ann;
Hanley, Daniel;
Trapp, Bruce D.

Publication type:

Article

Childhood ataxia with diffuse central nervous system hypomyelination.

Published in:

Annals of Neurology, 1994, v. 35, n. 3, p. 331, doi. 10.1002/ana.410350314

By:

Schiffmann, Raphael;
Moller, Johanna R.;
Trapp, Bruce D.;
Shih, Henry H-L.;
Farrer, Robert G.;
Katz, David A.;
Alger, Jeffry R.;
Parker, Colette C.;
Hauer, Peter E.;
Kaneski, Christine R.;
Heiss, John D.;
Kaye, Edward M.;
Quarles, Richard H.;
Brady, Roscoe O.;
Barton, Norman W.

Publication type:

Article

Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood-brain barrier.

Published in:

Annals of Neurology, 1993, v. 34, n. 3, p. 339, doi. 10.1002/ana.410340307

By:

Power, Christopher;
Kong, Pei-Ann;
Crawford, Thomas O.;
Wesselingh, Steven;
Glass, Jonathan D.;
McArthur, Justin C.;
Trapp, Bruce D.

Publication type:

Article

Dysmyelination in transgenic mice containing JC virus early region.

Published in:

Annals of Neurology, 1988, v. 23, n. 1, p. 38, doi. 10.1002/ana.410230108

By:

Trapp, Bruce D.;
Small, Judy A.;
Pulley, Michael;
Khoury, George;
Scangos, George A.

Publication type:

Article

Thymosin β4 is a shared antigen between lymphoid cells and oligodendrocytes of normal human brain.

Published in:

Annals of Neurology, 1986, v. 19, n. 4, p. 349, doi. 10.1002/ana.410190407

By:

Dalakas, Marinos C.;
Trapp, Bruce D.

Publication type:

Article

A quantitation of myelin-associated glycoprotein and myelin basic protein loss in different demyelinating disease.

Published in:

Annals of Neurology, 1985, v. 18, n. 3, p. 324, doi. 10.1002/ana.410180309

By:

Gendelman, Howard E.;
Pezeshkpour, Gholam H.;
Pressman, Norman J.;
Wolinsky, Jerry S.;
Quarles, Richard H.;
Dobersen, Michael J.;
Trapp, Bruce D.;
Kitt, Cheryl A.;
Aksamit, Allen;
Johnson, Richard T.

Publication type:

Article

Biochemical Characterization of Myelin Isolated from the Central Nervous System of Xenopus Tadpoles.

Published in:

Journal of Neurochemistry, 1980, v. 34, n. 5, p. 1241, doi. 10.1111/j.1471-4159.1980.tb09965.x

By:

Trapp, Bruce D.;
McIntyre, Laurence J.;
Quarles, Richard H.;
Nonaka, Genïchro;
Moser, Ann;
Maser, Hugo W.;
Webster, Henry de F.

Publication type:

Article

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.

Published in:

Journal of Neuroinflammation, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12974-015-0293-9

By:

Savarin, Carine;
Hinton, David R.;
Valentin-Torres, Alice;
Zhihong Chen;
Trapp, Bruce D.;
Bergmann, Cornelia C.;
Stohlman, Stephen A.

Publication type:

Article

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.

Published in:

2015

By:

Savarin, Carine;
Hinton, David R;
Valentin-Torres, Alice;
Chen, Zhihong;
Trapp, Bruce D;
Bergmann, Cornelia C;
Stohlman, Stephen A

Publication type:

journal article

Neurodegeneration in Multiple Sclerosis: Relationship to Neurological Disability.

Published in:

Neuroscientist, 1999, v. 5, n. 1, p. 48, doi. 10.1177/107385849900500107

By:

Trapp, Bruce D.;
Ransohoff, Richard M.;
Fisher, Elizabeth;
Rudick, Richard A.

Publication type:

Article

Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains.

Published in:

Nature Neuroscience, 2014, v. 17, n. 1, p. 121, doi. 10.1038/nn.3588

By:

Huynh, Jimmy L;
Garg, Paras;
Thin, Tin Htwe;
Yoo, Seungyeul;
Dutta, Ranjan;
Trapp, Bruce D;
Haroutunian, Vahram;
Zhu, Jun;
Donovan, Michael J;
Sharp, Andrew J;
Casaccia, Patrizia

Publication type:

Article

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.

Published in:

Nature Neuroscience, 2013, v. 16, n. 10, p. 1401, doi. 10.1038/nn.3505

By:

Kang, Zizhen;
Wang, Chenhui;
Zepp, Jarod;
Wu, Ling;
Sun, Kevin;
Zhao, Junjie;
Chandrasekharan, Unni;
DiCorleto, Paul E;
Trapp, Bruce D;
Ransohoff, Richard M;
Li, Xiaoxia

Publication type:

Article

The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination.

Published in:

Nature Neuroscience, 2009, v. 12, n. 11, p. 1398, doi. 10.1038/nn.2410

By:

Ying Chen;
Heng Wu;
Shuzong Wang;
Koito, Hisami;
Jianrong Li;
Feng Ye;
Hoang, Jenny;
Escobar, Sabine S.;
Gow, Alexander;
Arnett, Heather A.;
Trapp, Bruce D.;
Karandikar, Nitin J.;
Hsieh, Jenny;
Lu, Q. Richard

Publication type:

Article

Sensitivity of T1/T2-weighted ratio in detection of cortical demyelination is similar to magnetization transfer ratio using post-mortem MRI.

Published in:

Multiple Sclerosis Journal, 2022, v. 28, n. 2, p. 198, doi. 10.1177/13524585211014760

By:

Zheng, Yufan;
Dudman, Jessica;
Chen, Jacqueline T;
Mahajan, Kedar R;
Herman, Danielle;
Fox, Robert J;
Ontaneda, Daniel;
Trapp, Bruce D;
Nakamura, Kunio

Publication type:

Article

Juxtacortical susceptibility changes in progressive multifocal leukoencephalopathy at the gray–white matter junction correlates with iron-enriched macrophages.

Published in:

Multiple Sclerosis Journal, 2021, v. 27, n. 14, p. 2159, doi. 10.1177/1352458521999651

By:

Mahajan, Kedar R;
Amin, Moein;
Poturalski, Matthew;
Lee, Jonathan;
Herman, Danielle;
Zheng, Yufan;
Androjna, Caroline;
Howell, Mark;
Fox, Robert J;
Trapp, Bruce D;
Jones, Stephen E;
Nakamura, Kunio;
Ontaneda, Daniel

Publication type:

Article