Found: 9

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  • A Trem2<sup>R47H</sup> mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.

    Published in:
    Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00598-4
    By:
    • Tran, Kristine M.;
    • Kawauchi, Shimako;
    • Kramár, Enikö A.;
    • Rezaie, Narges;
    • Liang, Heidi Yahan;
    • Sakr, Jasmine S.;
    • Gomez-Arboledas, Angela;
    • Arreola, Miguel A.;
    • Cunha, Celia da;
    • Phan, Jimmy;
    • Wang, Shuling;
    • Collins, Sherilyn;
    • Walker, Amber;
    • Shi, Kai-Xuan;
    • Neumann, Jonathan;
    • Filimban, Ghassan;
    • Shi, Zechuan;
    • Milinkeviciute, Giedre;
    • Javonillo, Dominic I.;
    • Tran, Katelynn
    Publication type:
    Article

  • Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.

    Published in:
    Frontiers in Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnins.2021.785276
    By:
    • Javonillo, Dominic I.;
    • Tran, Kristine M.;
    • Phan, Jimmy;
    • Hingco, Edna;
    • Kramár, Enikö A.;
    • da Cunha, Celia;
    • Forner, Stefania;
    • Kawauchi, Shimako;
    • Milinkeviciute, Giedre;
    • Gomez-Arboledas, Angela;
    • Neumann, Jonathan;
    • Banh, Crystal E.;
    • Huynh, Michelle;
    • Matheos, Dina P.;
    • Rezaie, Narges;
    • Alcantara, Joshua A.;
    • Mortazavi, Ali;
    • Wood, Marcelo A.;
    • Tenner, Andrea J.;
    • MacGregor, Grant R.
    Publication type:
    Article

  • Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.

    Published in:
    Scientific Data, 2021, v. 8, n. 1, p. 1, doi. 10.1038/s41597-021-01054-y
    By:
    • Forner, Stefania;
    • Kawauchi, Shimako;
    • Balderrama-Gutierrez, Gabriela;
    • Kramár, Enikö A.;
    • Matheos, Dina P.;
    • Phan, Jimmy;
    • Javonillo, Dominic I.;
    • Tran, Kristine M.;
    • Hingco, Edna;
    • da Cunha, Celia;
    • Rezaie, Narges;
    • Alcantara, Joshua A.;
    • Baglietto-Vargas, David;
    • Jansen, Camden;
    • Neumann, Jonathan;
    • Wood, Marcelo A.;
    • MacGregor, Grant R.;
    • Mortazavi, Ali;
    • Tenner, Andrea J.;
    • LaFerla, Frank M.
    Publication type:
    Article

  • Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2794, doi. 10.1002/alz.13753
    By:
    • Soni, Neelakshi;
    • Hohsfield, Lindsay A.;
    • Tran, Kristine M.;
    • Kawauchi, Shimako;
    • Walker, Amber;
    • Javonillo, Dominic;
    • Phan, Jimmy;
    • Matheos, Dina;
    • Da Cunha, Celia;
    • Uyar, Asli;
    • Milinkeviciute, Giedre;
    • Gomez‐Arboledas, Angela;
    • Tran, Katelynn;
    • Kaczorowski, Catherine C.;
    • Wood, Marcelo A.;
    • Tenner, Andrea J.;
    • LaFerla, Frank M.;
    • Carter, Gregory W.;
    • Mortazavi, Ali;
    • Swarup, Vivek
    Publication type:
    Article

  • BIN1 K358R variant in 5xFAD mice ameliorates AB pathology and microgliosis.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.066218
    By:
    • Tran, Katelynn;
    • Milinkeviciute, Giedre;
    • Tran, Kristine M;
    • Phan, Jimmy;
    • Da Cunha, Celia;
    • Javonillo, Dominic I;
    • Kawauchi, Shimako;
    • Tenner, Andrea J;
    • LaFerla, Frank;
    • MacGregor, Grant R;
    • Green, Kim N
    Publication type:
    Article

  • Trem2<sup>R47H NSS</sup>; 5xFAD mice display age/disease progression‐dependent changes in plaques and plaque‐associated microglia, and increased plasma neurofilament light chain.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.062610
    By:
    • Tran, Kristine M;
    • Kawauchi, Shimako;
    • Javonillo, Dominic I;
    • Da Cunha, Celia;
    • Phan, Jimmy;
    • Rezaie, Narges;
    • Liang, Heidi Yahan;
    • Milinkeviciute, Giedre;
    • Gomez‐Arboledas, Angela;
    • Forner, Stefania;
    • Mortazavi, Ali;
    • Tenner, Andrea J;
    • LaFerla, Frank;
    • MacGregor, Grant R;
    • Green, Kim N
    Publication type:
    Article

  • The Clu‐rs2279590_h2kb variant increases axonal and neuritic damage in 5xFAD mice.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.066214
    By:
    • Milinkeviciute, Giedre;
    • Tran, Katelynn;
    • Tran, Kristine M;
    • Phan, Jimmy;
    • Da Cunha, Celia;
    • Javonillo, Dominic I;
    • Neumann, Jonathan;
    • Alcantara, Joshua A;
    • Walker, Amber;
    • Kawauchi, Shimako;
    • Tenner, Andrea J;
    • LaFerla, Frank;
    • MacGregor, Grant R;
    • Green, Kim N
    Publication type:
    Article

  • Late‐onset AD risk mutation PICALM<sup>H458R</sup> prevents plaque generation in 5xFAD mice.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.063718
    By:
    • Gomez‐Arboledas, Angela;
    • Tran, Kristine M;
    • Javonillo, Dominic I;
    • Phan, Jimmy;
    • Milinkeviciute, Giedre;
    • Da Cunha, Celia;
    • Forner, Stefania;
    • Kawauchi, Shimako;
    • Tenner, Andrea J;
    • LaFerla, Frank;
    • MacGregor, Grant R;
    • Green, Kim N
    Publication type:
    Article

  • Accumulation of periodic‐acid Schiff granules is increased in the presence of humanized amyloid beta.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055658
    By:
    • Forner, Stefania;
    • Javonillo, Dominic I;
    • Tran, Kristine M;
    • Phan, Jimmy;
    • Da Cunha, Celia;
    • Baglietto‐Vargas, David;
    • Kawauchi, Shimako;
    • Tenner, Andrea J;
    • LaFerla, Frank;
    • MacGregor, Grant R;
    • Green, Kim N
    Publication type:
    Article