OpenURL Connection Search

Select item for more details and to access through your institution.

Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model.
Published in:
2016
By:
- Horn, Margaux A.;
- Bode, Elizabeth F.;
- Borland, Samantha J.;
- Kirkwood, Graeme J.;
- Briston, Sarah J.;
- Richards, Mark A.;
- Dibb, Katharine M.;
- Trafford, Andrew W.
Publication type:
journal article
Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis.
Published in:
Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.690897
By:
- Denham, Nathan C.;
- Pearman, Charles M.;
- Madders, George W. P.;
- Smith, Charlotte E. R.;
- Trafford, Andrew W.;
- Dibb, Katharine M.
Publication type:
Article
Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3 and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response.
Published in:
Biochemical Journal, 2013, v. 456, n. 2, p. 205, doi. 10.1042/BJ20130591
By:
- BENNETT, Hayley J.;
- Bernard DAVENPORT, John;
- COLLINS, Richard F.;
- TRAFFORD, Andrew W.;
- PINALI, Christian;
- KITMITTO, Ashraf
Publication type:
Article
Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling.
Published in:
Physiological Reports, 2020, v. 8, n. 2, p. N.PAG, doi. 10.14814/phy2.14321
By:
- Radcliffe, Emma J.;
- Pearman, Charles M.;
- Watkins, Amy;
- Lawless, Michael;
- Kirkwood, Graeme J.;
- Saxton, Sophie N.;
- Eisner, David A.;
- Trafford, Andrew W.
Publication type:
Article
Author Correction: Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.
Published in:
2021
By:
- Hayter, Edward A.;
- Wehrens, Sophie M. T.;
- Van Dongen, Hans P. A.;
- Stangherlin, Alessandra;
- Gaddameedhi, Shobhan;
- Crooks, Elena;
- Barron, Nichola J.;
- Venetucci, Luigi A.;
- O'Neill, John S.;
- Brown, Timothy M.;
- Skene, Debra J.;
- Trafford, Andrew W.;
- Bechtold, David A.
Publication type:
Correction Notice
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22788-8
By:
- Hayter, Edward A.;
- Wehrens, Sophie M. T.;
- Van Dongen, Hans P. A.;
- Stangherlin, Alessandra;
- Gaddameedhi, Shobhan;
- Crooks, Elena;
- Barron, Nichola J.;
- Venetucci, Luigi A.;
- Neill, John S. O';
- Brown, Timothy M.;
- Skene, Debra J.;
- Trafford, Andrew W.;
- Bechtold, David A.
Publication type:
Article
An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes.
Published in:
Stem Cells Translational Medicine, 2014, v. 3, n. 4, p. 416, doi. 10.5966/sctm.2013-0105
By:
- YAN JIANG;
- HABIBOLLAH, SABA;
- TILGNER, KATARZYNA;
- COLLIN, JOSEPH;
- BARTA, TOMAS;
- AL-AAMA, JUMANA YOUSUF;
- TESAROV, LENKA;
- HUSSAIN, RAFIQUL;
- TRAFFORD, ANDREW W.;
- KIRKWOOD, GRAHAM;
- SERNAGOR, EVELYNE;
- ELEFTHERIOU, CYRIL G.;
- PRZYBORSKI, STEFAN;
- STOJKOVIĆ, MIODRAG;
- LAKO, MAJLINDA;
- KEAVNEY, BERNARD;
- ARMSTRONG, LYLE
Publication type:
Article
Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes.
Published in:
Cardiovascular Research, 2014, v. 104, n. 2, p. 347, doi. 10.1093/cvr/cvu201
By:
- Briston, Sarah J.;
- Dibb, Katharine M.;
- Solaro, R. John;
- Eisner, David A.;
- Trafford, Andrew W.
Publication type:
Article
Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions.
Published in:
Cardiovascular Research, 2014, v. 103, n. 4, p. 554, doi. 10.1093/cvr/cvu158
By:
- Greensmith, David J.;
- Galli, Gina L.J.;
- Trafford, Andrew W.;
- Eisner, David A.
Publication type:
Article
Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias.
Published in:
Cardiovascular Research, 2013, v. 98, n. 2, p. 192, doi. 10.1093/cvr/cvt018
By:
- Trafford, Andrew W.;
- Clarke, Jessica D.;
- Richards, Mark A.;
- Eisner, David A.;
- Dibb, Katharine M.
Publication type:
Article
Ca2+ wave probability is determined by the balance between SERCA2-dependent Ca2+ reuptake and threshold SR Ca2+ content.
Published in:
Cardiovascular Research, 2011, v. 90, n. 3, p. 503, doi. 10.1093/cvr/cvr013
By:
- Stokke, Mathis K.;
- Briston, Sarah J.;
- Jølle, Guro F.;
- Manzoor, Isma;
- Louch, William E.;
- Øyehaug, Leiv;
- Christensen, Geir;
- Eisner, David A.;
- Trafford, Andrew W.;
- Sejersted, Ole M.;
- Sjaastad, Ivar
Publication type:
Article
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.
Published in:
Cardiovascular Research, 2010, v. 86, n. 1, p. 63, doi. 10.1093/cvr/cvp401
By:
- Stokke, Mathis K.;
- Hougen, Karina;
- Sjaastad, Ivar;
- Louch, William E.;
- Briston, Sarah J.;
- Enger, Ulla H.;
- Andersson, Kristin B.;
- Christensen, Geir;
- Eisner, David A.;
- Sejersted, Ole M.;
- Trafford, Andrew W.
Publication type:
Article
The sarcoplasmic reticulum and arrhythmogenic calcium release.
Published in:
Cardiovascular Research, 2008, v. 77, n. 2, p. 285, doi. 10.1093/cvr/cvm009
By:
- Venetucci, Luigi A.;
- Trafford, Andrew W.;
- O'Neill, Stephen C.;
- Eisner, David A.
Publication type:
Article
Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42592-1
By:
- Lawless, Michael;
- Caldwell, Jessica L.;
- Radcliffe, Emma J.;
- Smith, Charlotte E. R.;
- Madders, George W. P.;
- Hutchings, David C.;
- Woods, Lori S.;
- Church, Stephanie J.;
- Unwin, Richard D.;
- Kirkwood, Graeme J.;
- Becker, Lorenz K.;
- Pearman, Charles M.;
- Taylor, Rebecca F.;
- Eisner, David A.;
- Dibb, Katharine M.;
- Trafford, Andrew. W.
Publication type:
Article
Interaction of background Ca2+ influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca2+ waves in sheep heart.
Published in:
Journal of Physiology, 2022, v. 600, n. 11, p. 2637, doi. 10.1113/JP282168
By:
- Hutchings, David C.;
- Madders, George W. P.;
- Niort, Barbara C.;
- Bode, Elizabeth F.;
- Waddell, Caitlin A.;
- Woods, Lori S.;
- Dibb, Katharine M.;
- Eisner, David A.;
- Trafford, Andrew W.
Publication type:
Article
Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep.
Published in:
2018
By:
- Pearman, Charles M.;
- Madders, George W. P.;
- Radcliffe, Emma J.;
- Kirkwood, Graeme J.;
- Lawless, Michael;
- Watkins, Amy;
- Smith, Charlotte E. R.;
- Trafford, Andrew W.;
- Eisner, David A.;
- Dibb, Katharine M.
Publication type:
journal article
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Published in:
Basic Research in Cardiology, 2022, v. 117, n. 1, p. 1, doi. 10.1007/s00395-022-00924-9
By:
- Hulikova, Alzbeta;
- Park, Kyung Chan;
- Loonat, Aminah A.;
- Gunadasa-Rohling, Mala;
- Curtis, M. Kate;
- Chung, Yu Jin;
- Wilson, Abigail;
- Carr, Carolyn A.;
- Trafford, Andrew W.;
- Fournier, Marjorie;
- Moshnikova, Anna;
- Andreev, Oleg A.;
- Reshetnyak, Yana K.;
- Riley, Paul R.;
- Smart, Nicola;
- Milne, Thomas A.;
- Crump, Nicholas T.;
- Swietach, Pawel
Publication type:
Article
Increased Ca buffering underpins remodelling of Ca2+ handling in old sheep atrial myocytes.
Published in:
Journal of Physiology, 2017, v. 595, n. 19, p. 6263, doi. 10.1113/JP274053
By:
- Clarke, Jessica D.;
- Caldwell, Jessica L.;
- Pearman, Charles M.;
- Eisner, David A.;
- Trafford, Andrew W.;
- Dibb, Katharine M.
Publication type:
Article
Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure.
Published in:
Journal of Physiology, 2011, v. 589, n. 6, p. 1367, doi. 10.1113/jphysiol.2010.203984
By:
- Briston, Sarah J.;
- Caldwell, Jessica L.;
- Horn, Margaux A.;
- Clarke, Jessica D.;
- Richards, Mark A.;
- Greensmith, David J.;
- Graham, Helen K.;
- Hall, Mark C. S.;
- Eisner, David A.;
- Dibb, Katharine M.;
- Trafford, Andrew W.
Publication type:
Article
Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure.
Published in:
Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.01380
By:
- Denham, Nathan C.;
- Pearman, Charles M.;
- Caldwell, Jessica L.;
- Madders, George W. P.;
- Eisner, David A.;
- Trafford, Andrew W.;
- Dibb, Katharine M.
Publication type:
Article
Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner.
Published in:
Journal of Pineal Research, 2022, v. 73, n. 3, p. 1, doi. 10.1111/jpi.12821
By:
- Smith, Kerri L. M.;
- Swiderska, Agnieszka;
- Lock, Mitchell C.;
- Graham, Lucia;
- Iswari, Wulan;
- Choudhary, Tashi;
- Thomas, Donna;
- Kowash, Hager M.;
- Desforges, Michelle;
- Cottrell, Elizabeth C.;
- Trafford, Andrew W.;
- Giussani, Dino A.;
- Galli, Gina L. J.
Publication type:
Article
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy.
Published in:
Journal of Pineal Research, 2022, v. 72, n. 1, p. 1, doi. 10.1111/jpi.12766
By:
- Hansell, Jeremy A.;
- Richter, Hans G.;
- Camm, Emily J.;
- Herrera, Emilio A.;
- Blanco, Carlos E.;
- Villamor, Eduardo;
- Patey, Olga V.;
- Lock, Mitchell C.;
- Trafford, Andrew W.;
- Galli, Gina L. J.;
- Giussani, Dino A.
Publication type:
Article
A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions.
Published in:
PLoS Computational Biology, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pcbi.1005714
By:
- Colman, Michael A.;
- Pinali, Christian;
- Trafford, Andrew W.;
- Zhang, Henggui;
- Kitmitto, Ashraf
Publication type:
Article

Found: 23

Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model.

Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis.

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P<sub>3</sub> and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response.

Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling.

Author Correction: Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.

Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.

An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes.

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes.

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions.

Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias.

Ca2+ wave probability is determined by the balance between SERCA2-dependent Ca2+ reuptake and threshold SR Ca2+ content.

Reduced SERCA2 abundance decreases the propensity for Ca<sup>2+</sup> wave development in ventricular myocytes.

The sarcoplasmic reticulum and arrhythmogenic calcium release.

Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.

Interaction of background Ca<sup>2+</sup> influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca<sup>2+</sup> waves in sheep heart.

Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep.

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.

Increased Ca buffering underpins remodelling of Ca<sup>2+</sup> handling in old sheep atrial myocytes.

Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure.

Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure.

Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner.

Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy.

A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions.