Works by Totonchi, Mehdi

Results: 84

Disease-Corrected Hepatocyte-Like Cells from Familial Hypercholesterolemia-Induced Pluripotent Stem Cells.

Published in:

Molecular Biotechnology, 2013, v. 54, n. 3, p. 863, doi. 10.1007/s12033-012-9635-3

By:

Fattahi, Faranak;
Asgari, Samira;
Pournasr, Behshad;
Seifinejad, Ali;
Totonchi, Mehdi;
Taei, Adeleh;
Aghdami, Nasser;
Salekdeh, Ghasem;
Baharvand, Hossein

Publication type:

Article

Strategies for whole-exome sequencing analysis in a case series study of familial male infertility.

Published in:

International Journal of Reproductive Biomedicine, 2020, v. 18, n. 5, p. 375, doi. 10.18502/ijrm.v13i5.7158

By:

Askari, Masomeh;
Tamandani, Dor Mohammad Kordi;
Almadani, Navid;
Totonchi, Mehdi

Publication type:

Article

Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40485-y

By:

Nouri-Keshtkar, Marjan;
Shojaei Shahrokhabadi, Mohadeseh;
Ghaheri, Azadeh;
Hosseini, Roya;
Ketabi, Hassan;
Farjam, Mojtaba;
Chen, Ding-Geng;
Rezaeian, Mehdi;
Homayounfar, Reza;
Tahamtani, Yaser;
Totonchi, Mehdi

Publication type:

Article

Current trends and future prospects of drug repositioning in gastrointestinal oncology.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1329244

By:

Fatemi, Nayeralsadat;
Karimpour, Mina;
Bahrami, Hoda;
Zali, Mohammad Reza;
Chaleshi, Vahid;
Riccio, Andrea;
Nazemalhosseini-Mojarad, Ehsan;
Totonchi, Mehdi

Publication type:

Article

rare frameshift mutation in SYCP1 is associated with human male infertility.

Published in:

Molecular Human Reproduction, 2022, v. 28, n. 4, p. 1, doi. 10.1093/molehr/gaac009

By:

Nabi, Soheila;
Askari, Masomeh;
Rezaei-Gazik, Maryam;
Salehi, Najmeh;
Almadani, Navid;
Tahamtani, Yaser;
Totonchi, Mehdi

Publication type:

Article

Direct visualization of pre-protamine 2 detects protamine assembly failures and predicts ICSI success.

Published in:

Molecular Human Reproduction, 2022, v. 28, n. 2, p. 1, doi. 10.1093/molehr/gaac004

By:

Rezaei-Gazik, Maryam;
Vargas, Alexandra;
Amiri-Yekta, Amir;
Vitte, Anne-Laure;
Akbari, Arvand;
Barral, Sophie;
Esmaeili, Vahid;
Chuffart, Florent;
Sadighi-Gilani, Mohammad Ali;
Couté, Yohann;
Eftekhari-Yazdi, Poopak;
Khochbin, Saadi;
Rousseaux, Sophie;
Totonchi, Mehdi

Publication type:

Article

Comprehensive somatic mutational analysis in glioblastoma: Implications for precision medicine approaches.

Published in:

PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0295698

By:

Azimi, Parisa;
Karimpour, Mina;
Yazdanian, Taravat;
Totonchi, Mehdi;
Ahmadiani, Abolhassan

Publication type:

Article

Clinical and genetic diagnosis of first cohort of differences of sexual development in the Iranian population.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2025, v. 38, n. 3, p. 279, doi. 10.1515/jpem-2024-0352

By:

Rastari, Mandana;
Askari, Masomeh;
McElreavey, Kenneth;
Bashamboo, Anu;
Rokhsattalab, Zeinab;
Razzaghy-Azar, Maryam;
Bakhshi, Mahdieh;
Totonchi, Mehdi

Publication type:

Article

Enhancing maturity in 3D kidney micro‐tissues through clonogenic cell combinations and endothelial integration.

Published in:

Journal of Cellular & Molecular Medicine, 2024, v. 28, n. 11, p. 1, doi. 10.1111/jcmm.18453

By:

Abdollahzadeh, Fatemeh;
Khoshdel‐Rad, Niloofar;
Bahrehbar, Khadijeh;
Erfanian, Saiedeh;
Ezzatizadeh, Vahid;
Totonchi, Mehdi;
Moghadasali, Reza

Publication type:

Article

Emerging Frontiers in Colorectal Cancer Therapy: From Targeted Molecules to Immunomodulatory Breakthroughs and Cell-Based Approaches.

Published in:

Digestive Diseases & Sciences, 2025, v. 70, n. 3, p. 919, doi. 10.1007/s10620-024-08774-2

By:

Fatemi, Nayeralsadat;
Mirbahari, Seyedeh Nasim;
Tierling, Sascha;
Sanjabi, Fatemeh;
Shahrivari, Shabnam;
AmeliMojarad, Mandana;
Amelimojarad, Melika;
Mirzaei Rezaei, Meygol;
Nobaveh, Parsa;
Totonchi, Mehdi;
Nazemalhosseini Mojarad, Ehsan

Publication type:

Article

Proposing a novel unsupervised stack ensemble of deep and conventional image segmentation (SEDCIS) method for localizing vitiligo lesions in skin images.

Published in:

Skin Research & Technology, 2021, v. 27, n. 2, p. 126, doi. 10.1111/srt.12920

By:

Khatibi, Toktam;
Rezaei, Niloofar;
Ataei Fashtami, Leila;
Totonchi, Mehdi

Publication type:

Article

Prediction of the treatment response in ovarian cancer: a ctDNA approach.

Published in:

Journal of Ovarian Research, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13048-020-00729-1

By:

Sharbatoghli, Mina;
Vafaei, Somayeh;
Aboulkheyr Es, Hamidreza;
Asadi-Lari, Mohsen;
Totonchi, Mehdi;
Madjd, Zahra

Publication type:

Article

Improvement of Mouse Preantral Follicle Survival and Development following Co-Culture with Ovarian Parenchyma Cell Suspension.

Published in:

International Journal of Fertility & Sterility, 2024, v. 18, n. 2, p. 153, doi. 10.22074/IJFS.2023.1990372.1439

By:

Salehi, Javad Najafi;
Eimani, Hussein;
Shahverdi, Abdolhossein;
Totonchi, Mehdi;
Fathi, Rouhollah;
Moosavi, Seyed Akbar;
Mofrad, Seyed Mohamad Javad Taher;
Tahaei, Leila Sadat

Publication type:

Article

Risk Factors Associated with Recurrent Pregnancy Loss and Outcome of Pre-Implantation Genetic Screening of Affected Couples.

Published in:

International Journal of Fertility & Sterility, 2021, v. 15, n. 4, p. 269, doi. 10.22074/IJFS.2021.137626.1027

By:

Fatemi, Nayeralsadat;
Varkiani, Maryam;
Ramezanali, Fariba;
Babaabasi, Babak;
Ghaheri, Azadeh;
Biglari, Alireza;
Totonchi, Mehdi

Publication type:

Article

P38 initiates degeneration of midbrain GABAergic and glutamatergic neurons in diabetes models.

Published in:

European Journal of Neuroscience, 2022, v. 56, n. 1, p. 3755, doi. 10.1111/ejn.15686

By:

Farhadi, Aisan;
Totonchi, Mehdi;
Nabavi, Seyed Masood;
Baharvand, Hossein;
Pakdaman, Hossein;
Hajizadeh‐Saffar, Ensiyeh;
Mousavi, Seyed Ahmad;
Hadi, Fatemeh;
Al‐Sinawi, Hamed;
Li, Quan;
Zhang, Jin‐San;
Tahamtani, Yaser;
Shahpasand, Koorosh

Publication type:

Article

Quantitative expression of developmental genes, Pou5fl (Oct4) and Mest (Pegl), in vitrified mouse embryos.

Published in:

Iranian Journal of Reproductive Medicine, 2013, v. 11, n. 9, p. 733

By:

Rajabpour-Niknam, Masoumeh;
Totonchi, Mehdi;
Shahhosseini, Maryam;
Farrokhi, Ali;
Alipour, Hiva;
Eftekhari-Yazdi, Poopak

Publication type:

Article

CpG Island Methylation of the Rap1 Gap Gene in Medullary Thyroid Cancer.

Published in:

Archives of Iranian Medicine (AIM), 2022, v. 25, n. 3, p. 171, doi. 10.34172/aim.2022.29

By:

Faam, Bita;
Ghadiri, Ata. A.;
Ghaffari, Mohammad Ali;
Totonchi, Mehdi;
Amouzegar, Atieh;
Azizi, Fereidoun;
Shahbazian, Hajiehbibi;
Hashemitabar, Mahmoud;
Fanaei, Seyed Ahmad;
Khorsandi, Layasadat

Publication type:

Article

A novel panel of blood-based microRNAs capable of discrimination between benign breast disease and breast cancer at early stages.

Published in:

RNA Biology, 2021, v. 18, p. 747, doi. 10.1080/15476286.2021.1989218

By:

Sadeghi, Hanieh;
Kamal, Aryan;
Ahmadi, Marzieh;
Najafi, Hadi;
Sharifi Zarchi, Ali;
Haddad, Peyman;
Shayestehpour, Bahareh;
Kamkar, Leila;
Salamati, Masoumeh;
Geranpayeh, Loabat;
Lashkari, Marzieh;
Totonchi, Mehdi

Publication type:

Article

Increased robustness of early embryogenesis through collective decision-making by key transcription factors.

Published in:

BMC Systems Biology, 2015, v. 9, n. 1, p. 1, doi. 10.1186/s12918-015-0169-8

By:

Sharifi-Zarchi, Ali;
Totonchi, Mehdi;
Khaloughi, Keynoush;
Karamzadeh, Razieh;
Araúzo-Bravo, Marcos J.;
Baharvand, Hossein;
Tusserkani, Ruzbeh;
Pezeshk, Hamid;
Chitsaz, Hamidreza;
Sadeghi, Mehdi

Publication type:

Article

Gene alterations and expression spectrum of SPATA33 in nonobstructive azoospermic Iranian men.

Published in:

Molecular Reproduction & Development, 2018, v. 85, n. 10, p. 760, doi. 10.1002/mrd.23051

By:

Monsef, Ladan;
Borjian Boroujeni, Parnaz;
Totonchi, Mehdi;
Sabbaghian, Marjan;
Mohseni Meybodi, Anahita

Publication type:

Article

Identification of the Molecular Events Involved in the Development of Prefrontal Cortex Through the Analysis of RNA-Seq Data From BrainSpan.

Published in:

ASN Neuro (Sage Publications, Ltd.), 2019, v. 11, p. N.PAG, doi. 10.1177/1759091419854627

By:

Najafi, Hadi;
Naseri, Mohadeseh;
Zahiri, Javad;
Totonchi, Mehdi;
Sadeghizadeh, Majid

Publication type:

Article

The construction of a testis transcriptional cell atlas from embryo to adult reveals various somatic cells and their molecular roles.

Published in:

Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04722-2

By:

Salehi, Najmeh;
Totonchi, Mehdi

Publication type:

Article

DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism.

Published in:

BMC Genomics, 2017, v. 18, p. 1, doi. 10.1186/s12864-017-4353-7

By:

Sharifi-Zarchi, Ali;
Gerovska, Daniela;
Adachi, Kenjiro;
Totonchi, Mehdi;
Pezeshk, Hamid;
Taft, Ryan J.;
Schöler, Hans R.;
Chitsaz, Hamidreza;
Sadeghi, Mehdi;
Baharvand, Hossein;
Araúzo-Bravo, Marcos J.

Publication type:

Article

A mechanical non-enzymatic method for isolation of mouse embryonic fibroblasts.

Published in:

Molecular Biology Reports, 2020, v. 47, n. 11, p. 8881, doi. 10.1007/s11033-020-05940-3

By:

Hosseini, Vahid;
Kalantary-Charvadeh, Ashkan;
Hasegawa, Kouichi;
Nazari Soltan Ahmad, Saeed;
Rahbarghazi, Reza;
Mahdizadeh, Amir;
Darabi, Masoud;
Totonchi, Mehdi

Publication type:

Article

Predicted Cellular and Molecular Actions of Lithium in the Treatment of Bipolar Disorder: An In Silico Study.

Published in:

2020

By:

Najafi, Hadi;
Totonchi, Mehdi;
Sadeghizadeh, Majid

Publication type:

journal article

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine.

Published in:

International Journal of Cancer, 2022, v. 151, n. 12, p. 2068, doi. 10.1002/ijc.34186

By:

Fatemi, Nayeralsadat;
Tierling, Sascha;
Es, Hamidreza Aboulkheyr;
Varkiani, Maryam;
Mojarad, Ehsan Nazemalhosseini;
Aghdaei, Hamid Asadzadeh;
Walter, Jörn;
Totonchi, Mehdi

Publication type:

Article

In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells.

Published in:

Journal of Ovarian Research, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13048-023-01315-x

By:

Mirbahari, Seyedeh Nasim;
Amorim, Christiani A.;
Hassani, Fatemeh;
Totonchi, Mehdi;
Haddadi, Mahnaz;
valojerdi, Mojtaba Rezazadeh;
Dalman, Azam

Publication type:

Article

Gene expression profile of placentomes and clinical parameters in the cows with retained placenta.

Published in:

BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08989-5

By:

Moradi, Mehdi;
Zhandi, Mahdi;
Sharafi, Mohsen;
Akbari, Arvand;
Atrabi, Mohammad Jafari;
Totonchi, Mehdi

Publication type:

Article

HNF4α is possibly the missing link between epithelial–mesenchymal transition and Warburg effect during hepatocarcinogenesis.

Published in:

Cancer Science, 2023, v. 114, n. 4, p. 1337, doi. 10.1111/cas.15686

By:

Shokouhian, Bahare;
Negahdari, Babak;
Heydari, Zahra;
Totonchi, Mehdi;
Aboulkheyr Es, Hamidreza;
Piryaei, Abbas;
Mostafavi, Ebrahim;
Vosough, Massoud

Publication type:

Article

iMM1865: A New Reconstruction of Mouse Genome-Scale Metabolic Model.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63235-w

By:

Khodaee, Saeideh;
Asgari, Yazdan;
Totonchi, Mehdi;
Karimi-Jafari, Mohammad Hossein

Publication type:

Article

A missense mutation in NR5A1 causing female to male sex reversal: A case report.

Published in:

Andrologia, 2020, v. 52, n. 6, p. 1, doi. 10.1111/and.13585

By:

Askari, Masomeh;
Rastari, Mandana;
Seresht‐Ahmadi, Mehrshad;
McElreavey, Kenneth;
Bashamboo, Anu;
Razzaghy‐Azar, Maryam;
Totonchi, Mehdi

Publication type:

Article

Rare case of an oligospermic male with 46,XX/46,XY tetragametic chimerism.

Published in:

Andrologia, 2019, v. 51, n. 7, p. N.PAG, doi. 10.1111/and.13290

By:

Magharehabed, Mahshad;
Almadani, Navid;
Askari, Masomeh;
Naji, Masoumeh;
Akbari, Arvand;
Gourabi, Hamid;
Sedighi Gilani, Mohammad Ali;
Reyhani Sabet, Fakhredin;
Masoudi, Najmeh‐Sadat;
Totonchi, Mehdi

Publication type:

Article

Circulating microRNA panels for multi-cancer detection and gastric cancer screening: leveraging a network biology approach.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02091-x

By:

Kamkar, Leila;
Saberi, Samaneh;
Totonchi, Mehdi;
Kavousi, Kaveh

Publication type:

Article

Whole exome sequencing identifies MAP3K1, MSH2, and MLH1 as potential cancer‐predisposing genes in familial early‐onset colorectal cancer.

Published in:

Kaohsiung Journal of Medical Sciences, 2023, v. 39, n. 9, p. 896, doi. 10.1002/kjm2.12715

By:

Fatemi, Nayeralsadat;
Tu, Siang‐Jyun;
Chung, Chin‐Chun;
Moghadam, Pardis Ketabi;
Mojarad, Ehsan Nazemalhosseini;
Sadeghi, Amir;
Totonchi, Mehdi;
Aghdaei, Hamid Asadzadeh;
Chang, Jan‐Gowth

Publication type:

Article

CNFE-SE: a novel approach combining complex network-based feature engineering and stacked ensemble to predict the success of intrauterine insemination and ranking the features.

Published in:

2021

By:

Ranjbari, Sima;
Khatibi, Toktam;
Vosough Dizaji, Ahmad;
Sajadi, Hesamoddin;
Totonchi, Mehdi;
Ghaffari, Firouzeh

Publication type:

journal article

Derivation of new human embryonic stem cell lines from preimplantation genetic screening and diagnosis-analyzed embryos.

Published in:

In Vitro Cellular & Developmental Biology Animal, 2010, v. 46, n. 3/4, p. 395, doi. 10.1007/s11626-010-9293-3

By:

Taei, Adeleh;
Gourabi, Hamid;
Seifinejad, Ali;
Totonchi, Mehdi;
Shahbazi, Ebrahim;
Valojerdi, Mojtaba;
Eftekhari, Poopak;
Karimian, Leila;
Baharvand, Hossein

Publication type:

Article

FMR1 premutation: not only important in premature ovarian failure but also in diminished ovarian reserve.

Published in:

Human Fertility, 2017, v. 20, n. 2, p. 120, doi. 10.1080/14647273.2016.1255356

By:

Eslami, Ali;
Farahmand, Kamelia;
Totonchi, Mehdi;
Madani, Tahereh;
Asadpour, Ummulbanin;
Zari Moradi, Shabnam;
Gourabi, Hamid;
Mohseni-Meybodi, Anahita

Publication type:

Article

Effect of Prepubertal Exposure to CdCl2 on the Liver, Hematological, and Biochemical Parameters in Female Rats; an Experimental Study.

Published in:

Biological Trace Element Research, 2020, v. 194, n. 2, p. 472, doi. 10.1007/s12011-019-01800-9

By:

Saedi, Saman;
Jafarzadeh Shirazi, Mohammad Reza;
Totonchi, Mehdi;
Zamiri, Mohammad Javad;
Derakhshanfar, Amin

Publication type:

Article

RAP1GAP Functions as a Tumor Suppressor Gene and Is Regulated by DNA Methylation in Differentiated Thyroid Cancer.

Published in:

Cytogenetic & Genome Research, 2021, v. 161, n. 5, p. 227, doi. 10.1159/000516122

By:

Faam, Bita;
Ghaffari, Mohammad A.;
Khorsandi, Layasadat;
Ghadiri, Ata A.;
Totonchi, Mehdi;
Amouzegar, Atieh;
Fanaei, S. Ahmad;
Azizi, Fereidoun;
Shahbazian, Hajeih B.;
Hashemi Tabar, Mahmoud

Publication type:

Article

The effect of cryopreservation on DNA methylation patterns of the chromosome 15q11-q13 region in human spermatozoa.

Published in:

2020

By:

Khosravizadeh, Zahra;
Hassanzadeh, Gholamreza;
Tavakkoly Bazzaz, Javad;
Alizadeh, Fatemeh;
Totonchi, Mehdi;
Salehi, Ensieh;
Khodamoradi, Kajal;
Khanehzad, Maryam;
Hosseini, Seyed Reza;
Abolhassani, Farid

Publication type:

journal article

Establishment and characterization of human theca stem cells and their differentiation into theca progenitor cells.

Published in:

Journal of Cellular Biochemistry, 2018, v. 119, n. 12, p. 9853, doi. 10.1002/jcb.27306

By:

Dalman, Azam;
Totonchi, Mehdi;
Valojerdi, Mojtaba Rezazadeh

Publication type:

Article

Genomic integrity of ground‐state pluripotency.

Published in:

Journal of Cellular Biochemistry, 2018, v. 119, n. 12, p. 9781, doi. 10.1002/jcb.27296

By:

Jafari, Narges;
Giehr, Pascal;
Hesaraki, Mahdi;
Baas, Roy;
Graaf, Petra;
Timmers, H. T. Marc;
Walter, Jörn;
Baharvand, Hossein;
Totonchi, Mehdi

Publication type:

Article

Pathway-driven analysis of synthetic lethal interactions in cancer using perturbation screens.

Published in:

Life Science Alliance, 2024, v. 7, n. 1, p. 1, doi. 10.26508/lsa.202302268

By:

Karimpour, Mina;
Totonchi, Mehdi;
Behmanesh, Mehrdad;
Montazeri, Hesam

Publication type:

Article

Integration and gene co-expression network analysis of scRNA-seq transcriptomes reveal heterogeneity and key functional genes in human spermatogenesis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98267-3

By:

Salehi, Najmeh;
Karimi-Jafari, Mohammad Hossein;
Totonchi, Mehdi;
Amiri-Yekta, Amir

Publication type:

Article

Genomic alterations and possible druggable mutations in carcinoma of unknown primary (CUP).

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94678-4

By:

Es, Hamidreza Aboulkheyr;
Mahdizadeh, Hamid;
Asl, Amir Abbas Hedayati;
Totonchi, Mehdi

Publication type:

Article

Thrombophilic genes alterations as risk factor for recurrent pregnancy loss.

Published in:

2016

By:

Farahmand, Kamelia;
Totonchi, Mehdi;
Hashemi, Mehrdad;
Reyhani Sabet, Fakhreddin;
Kalantari, Hamid;
Gourabi, Hamid;
Mohseni Meybodi, Anahita

Publication type:

journal article

α‐synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease.

Published in:

Journal of Neurochemistry, 2021, v. 157, n. 3, p. 727, doi. 10.1111/jnc.15257

By:

Hadi, Fatemeh;
Akrami, Hassan;
Totonchi, Mehdi;
Barzegar, Abdolrazagh;
Nabavi, Seyed Massood;
Shahpasand, Koorosh

Publication type:

Article

Co-culture of human cryopreserved fragmented ovarian tissue with theca progenitor cells derived from theca stem cells.

Published in:

Journal of Assisted Reproduction & Genetics, 2023, v. 40, n. 7, p. 1611, doi. 10.1007/s10815-023-02799-8

By:

Dalman, Azam;
Adib, Samane;
Amorim, Christiani A.;
Pirjani, Reihaneh;
Totonchi, Mehdi;
Valojerdi, Mojtaba Rezazadeh

Publication type:

Article

Association of MOV10L1 gene polymorphisms and male infertility in azoospermic men with complete maturation arrest.

Published in:

Journal of Assisted Reproduction & Genetics, 2014, v. 31, n. 7, p. 865, doi. 10.1007/s10815-014-0240-1

By:

Sarkardeh, Homa;
Totonchi, Mehdi;
Asadpour, Ommolbanin;
Sadighi Gilani, Mohammad;
Zamani Esteki, Masoud;
Almadani, Navid;
Borjian Boroujeni, Parnaz;
Gourabi, Hamid

Publication type:

Article

Rare missense variant in MSH4 associated with primary gonadal failure in both 46, XX and 46, XY individuals.

Published in:

2021

By:

Akbari, Arvand;
Padidar, Kimiya;
Salehi, Najmeh;
Mashayekhi, Mehri;
Almadani, Navid;
Gilani, Mohammad Ali Sadighi;
Bashambou, Anu;
McElreavey, Ken;
Totonchi, Mehdi;
Sadighi Gilani, Mohammad Ali

Publication type:

journal article