Works by Toth‐Petroczy, Agnes

Results: 16

DeMAG predicts the effects of variants in clinically actionable genes by integrating structural and evolutionary epistatic features.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37661-z

By:

Luppino, Federica;
Adzhubei, Ivan A.;
Cassa, Christopher A.;
Toth-Petroczy, Agnes

Publication type:

Article

An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors.

Published in:

PLoS Biology, 2016, v. 14, n. 3, p. 1, doi. 10.1371/journal.pbio.1002396

By:

Laurino, Paola;
Tóth-Petróczy, Ágnes;
Meana-Pañeda, Rubén;
Lin, Wei;
Truhlar, Donald G.;
Tawfik, Dan S.

Publication type:

Article

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.

Published in:

NPJ Genomic Medicine, 2018, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41525-018-0060-9

By:

Haghighi, Alireza;
Krier, Joel B.;
Toth-Petroczy, Agnes;
Cassa, Christopher A.;
Frank, Natasha Y.;
Carmichael, Nikkola;
Fieg, Elizabeth;
Bjonnes, Andrew;
Mohanty, Anwoy;
Briere, Lauren C.;
Lincoln, Sharyn;
Lucia, Stephanie;
Gupta, Vandana A.;
Söylemez, Onuralp;
Sutti, Sheila;
Kooshesh, Kameron;
Qiu, Haiyan;
Fay, Christopher J.;
Perroni, Victoria;
Valerius, Jamie

Publication type:

Article

Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 8, p. 1, doi. 10.1371/journal.pcbi.1004421

By:

Rockah-Shmuel, Liat;
Tóth-Petróczy, Ágnes;
Tawfik, Dan S.

Publication type:

Article

Malleable Machines in Transcription Regulation: The Mediator Complex.

Published in:

PLoS Computational Biology, 2008, v. 4, n. 12, p. 1, doi. 10.1371/journal.pcbi.1000243

By:

Tóth-Petróczy, Ágnes;
Oldfield, Christopher J.;
Simon, István;
Takagi, Yuichiro;
Dunker, A. Keith;
Uversky, Vladimir N.;
Fuxreiter, Monika

Publication type:

Article

PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-55089-x

By:

Hadarovich, Anna;
Singh, Hari Raj;
Ghosh, Soumyadeep;
Scheremetjew, Maxim;
Rostam, Nadia;
Hyman, Anthony A.;
Toth-Petroczy, Agnes

Publication type:

Article

deTELpy: Python package for high-throughput detection of amino acid substitutions in mass spectrometry datasets.

Published in:

Bioinformatics, 2024, v. 40, n. 7, p. 1, doi. 10.1093/bioinformatics/btae424

By:

Landerer, Cedric;
Scheremetjew, Maxim;
Moon, HongKee;
Hersemann, Lena;
Toth-Petroczy, Agnes

Publication type:

Article

The EVcouplings Python framework for coevolutionary sequence analysis.

Published in:

Bioinformatics, 2019, v. 35, n. 9, p. 1582, doi. 10.1093/bioinformatics/bty862

By:

Hopf, Thomas A;
Green, Anna G;
Mersmann, Sophia;
Ingraham, John B;
Toth-Petroczy, Agnes;
Brock, Kelly;
Riesselman, Adam J;
Kang, Chan;
Marks, Debora S;
Schubert, Benjamin;
Schärfe, Charlotta P I;
Palmedo, Perry;
Sheridan, Robert;
Draizen, Eli J;
Dallago, Christian;
Sander, Chris

Publication type:

Article

novoCaller: a Bayesian network approach for de novo variant calling from pedigree and population sequence data.

Published in:

Bioinformatics, 2019, v. 35, n. 7, p. 1174, doi. 10.1093/bioinformatics/bty749

By:

Mohanty, Anwoy Kumar;
Vuzman, Dana;
Cassa, Christopher;
Toth-Petroczy, Agnes;
Francioli, Laurent;
Sunyaev, Shamil

Publication type:

Article

Environment modulates protein heterogeneity through transcriptional and translational stop codon readthrough.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48387-x

By:

Romero Romero, Maria Luisa;
Poehls, Jonas;
Kirilenko, Anastasiia;
Richter, Doris;
Jumel, Tobias;
Shevchenko, Anna;
Toth-Petroczy, Agnes

Publication type:

Article

SHARK‐capture identifies functional motifs in intrinsically disordered protein regions.

Published in:

Protein Science: A Publication of the Protein Society, 2025, v. 34, n. 4, p. 1, doi. 10.1002/pro.70091

By:

Chow, Chi Fung Willis;
Lenz, Swantje;
Scheremetjew, Maxim;
Ghosh, Soumyadeep;
Richter, Doris;
Jegers, Ceciel;
von Appen, Alexander;
Alberti, Simon;
Toth‐Petroczy, Agnes

Publication type:

Article

Phenotypic mutations contribute to protein diversity and shape protein evolution.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4397

By:

Romero Romero, Maria Luisa;
Landerer, Cedric;
Poehls, Jonas;
Toth‐Petroczy, Agnes

Publication type:

Article

Fitness Effects of Phenotypic Mutations at Proteome-Scale Reveal Optimality of Translation Machinery.

Published in:

Molecular Biology & Evolution, 2024, v. 41, n. 3, p. 1, doi. 10.1093/molbev/msae048

By:

Landerer, Cedric;
Poehls, Jonas;
Toth-Petroczy, Agnes

Publication type:

Article

Protein Insertions and Deletions Enabled by Neutral Roaming in Sequence Space.

Published in:

Molecular Biology & Evolution, 2013, v. 30, n. 4, p. 761

By:

Tóth-Petróczy, Ágnes;
Tawfik, Dan S.

Publication type:

Article

Deep learning tools predict variants in disordered regions with lower sensitivity.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11534-9

By:

Luppino, Federica;
Lenz, Swantje;
Chow, Chi Fung Willis;
Toth-Petroczy, Agnes

Publication type:

Article

Correlated Occurrence and Bypass of Frame-Shifting Insertion-Deletions (InDels) to Give Functional Proteins.

Published in:

PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003882

By:

Rockah-Shmuel, Liat;
Tóth-Petróczy, Ágnes;
Sela, Asaf;
Wurtzel, Omri;
Sorek, Rotem;
Tawfik, Dan S.

Publication type:

Article