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Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00357-z
By:
- Ali, Hassan A.;
- Karasinska, Joanna M.;
- Topham, James T.;
- Johal, Danisha;
- Kalloger, Steve;
- Metcalfe, Andrew;
- Warren, Cassia S.;
- Miyagi, Anthony;
- Tao, Lan V.;
- Kevorkova, Maya;
- Chafe, Shawn C.;
- McDonald, Paul C.;
- Dedhar, Shoukat;
- Parker, Seth J.;
- Renouf, Daniel J.;
- Schaeffer, David F.
Publication type:
Article
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33718-7
By:
- Topham, James T.;
- Tsang, Erica S.;
- Karasinska, Joanna M.;
- Metcalfe, Andrew;
- Ali, Hassan;
- Kalloger, Steve E.;
- Csizmok, Veronika;
- Williamson, Laura M.;
- Titmuss, Emma;
- Nielsen, Karina;
- Negri, Gian Luca;
- Spencer Miko, Sandra E.;
- Jang, Gun Ho;
- Denroche, Robert E.;
- Wong, Hui-li;
- O'Kane, Grainne M.;
- Moore, Richard A.;
- Mungall, Andrew J.;
- Loree, Jonathan M.;
- Notta, Faiyaz
Publication type:
Article
The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32591-8
By:
- Renouf, Daniel J.;
- Loree, Jonathan M.;
- Knox, Jennifer J.;
- Topham, James T.;
- Kavan, Petr;
- Jonker, Derek;
- Welch, Stephen;
- Couture, Felix;
- Lemay, Frederic;
- Tehfe, Mustapha;
- Harb, Mohammed;
- Aucoin, Nathalie;
- Ko, Yoo-Joung;
- Tang, Patricia A.;
- Ramjeesingh, Ravi;
- Meyers, Brandon M.;
- Kim, Christina A.;
- Du, Pan;
- Jia, Shidong;
- Schaeffer, David F.
Publication type:
Article
Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer.
Published in:
Therapeutic Advances in Medical Oncology, 2023, p. 1, doi. 10.1177/17588359231183682
By:
- Boutin, Mélina;
- Topham, James T.;
- Feilotter, Harriet;
- Kennecke, Hagen F.;
- Couture, Félix;
- Harb, Mohammed;
- Kavan, Peter;
- Berry, Scott;
- Lim, Howard J.;
- Goffin, John R.;
- Ahmad, Chaudhary;
- Lott, Anthony;
- Renouf, Daniel J.;
- Jonker, Derek J.;
- Tu, Dongsheng;
- O'Callaghan, Chris J.;
- Chen, Eric X.;
- Loree, Jonathan M.
Publication type:
Article
Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinoma.
Published in:
Therapeutic Advances in Medical Oncology, 2023, p. 1, doi. 10.1177/17588359231157651
By:
- Topham, James T.;
- Renouf, Daniel J.;
- Schaeffer, David F.
Publication type:
Article
Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma.
Published in:
Cancer Medicine, 2021, v. 10, n. 3, p. 1155, doi. 10.1002/cam4.3695
By:
- Naso, Julia R.;
- Topham, James T.;
- Karasinska, Joanna M.;
- Lee, Michael K.C.;
- Kalloger, Steve E.;
- Wong, Hui‐li;
- Nelson, Jessica;
- Moore, Richard A.;
- Mungall, Andrew J.;
- Jones, Steven J.M.;
- Laskin, Janessa;
- Marra, Marco A.;
- Renouf, Daniel J.;
- Schaeffer, David F.
Publication type:
Article
Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer.
Published in:
2020
By:
- Mendis, Shehara;
- Alcaide, Miguel;
- Topham, James T.;
- Johnson, Benny;
- Morin, Ryan D.;
- Chu, Jenny;
- Bosdet, Ian;
- Kopetz, Scott;
- Karsan, Aly;
- Gill, Sharlene;
- Laskin, Janessa;
- Jones, Steven J. M.;
- Marra, Marco A.;
- Schaeffer, David F.;
- Renouf, Daniel J.;
- Loree, Jonathan M.
Publication type:
journal article
Stroma vs epithelium‐enhanced prognostics through histologic stratification in pancreatic ductal adenocarcinoma.
Published in:
International Journal of Cancer, 2021, v. 148, n. 2, p. 481, doi. 10.1002/ijc.33304
By:
- Kalloger, Steve E.;
- Karasinska, Joanna M.;
- Keung, Martin S.;
- Thompson, Danielle L.;
- Ho, Julie;
- Chow, Christine;
- Gao, Dongxia;
- Topham, James T.;
- Warren, Cassia;
- Wong, Hui‐Li;
- Lee, Michael Kuan‐Ching;
- Renouf, Daniel J.;
- Schaeffer, David F.
Publication type:
Article
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00368-x
By:
- Tsang, Erica S.;
- Csizmok, Veronika;
- Williamson, Laura M.;
- Pleasance, Erin;
- Topham, James T.;
- Karasinska, Joanna M.;
- Titmuss, Emma;
- Schrader, Intan;
- Yip, Stephen;
- Tessier-Cloutier, Basile;
- Mungall, Karen;
- Ng, Tony;
- Sun, Sophie;
- Lim, Howard J.;
- Loree, Jonathan M.;
- Laskin, Janessa;
- Marra, Marco A.;
- Jones, Steven J. M.;
- Schaeffer, David F.;
- Renouf, Daniel J.
Publication type:
Article
Sequencing Strategies to Guide Decision Making in Cancer Treatment.
Published in:
2016
By:
- Topham, James T.;
- Marra, Marco A.
Publication type:
journal article
Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study.
Published in:
JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 8, p. 994, doi. 10.1093/jnci/djad095
By:
- Huey, Ryan W;
- Shah, Aakash Tushar;
- Reddi, Honey V;
- Dasari, Priyadarsini;
- Topham, James T;
- Hwang, Hyunsoo;
- Dhillon, Nishat;
- Willett, Anneleis;
- Smaglo, Brandon G;
- Estrella, Jeannelyn S;
- Rashid, Asif;
- Matamoros, Aurelio;
- Overman, Michael J;
- Choquette, Linda;
- Omerza, Greg;
- Kelly, Kevin;
- Wang, Xuemei;
- Loree, Jonathan M;
- Rueter, Jens;
- Varadhachary, Gauri R
Publication type:
Article

Found: 11