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APC and the three-hit hypothesis.
Published in:
Oncogene, 2009, v. 28, n. 1, p. 146, doi. 10.1038/onc.2008.361
By:
- Segditsas, S.;
- Rowan, A. J.;
- Howarth, K.;
- Jones, A.;
- Leedham, S.;
- Wright, N. A.;
- Gorman, P.;
- Chambers, W.;
- Domingo, E.;
- Roylance, R. R.;
- Sawyer, E. J.;
- Sieber, O. M.;
- Tomlinson, I. P. M.
Publication type:
Article
THE INTERACTIONS OF APC, E-CADHERIN AND β-CATENIN IN TUMOUR DEVELOPMENT AND PROGRESSION.
Published in:
Journal of Pathology, 1997, v. 182, n. 2, p. 128, doi. 10.1002/(SICI)1096-9896(199706)182:2<128::AID-PATH839>3.0.CO;2-Q
By:
- ILYAS, M.;
- TOMLINSON, I. P. M.
Publication type:
Article
THE FREQUENCY AND MECHANISM OF LOSS OF HETEROZYGOSITY ON CHROMOSOME 11q IN BREAST CANCER.
Published in:
Journal of Pathology, 1996, v. 180, n. 1, p. 38, doi. 10.1002/(SICI)1096-9896(199609)180:1<38::AID-PATH638>3.0.CO;2-C
By:
- TOMLINSON, I. P. M.;
- NICOLAI, H.;
- SOLOMON, E.;
- BODMER, W. F.
Publication type:
Article
CLINICO-PATHOLOGICAL FEATURES AND p53 EXPRESSION IN LEFT-SIDED SPORADIC COLORECTAL CANCERS WITH AND WITHOUT MICROSATELLITE INSTABILITY.
Published in:
Journal of Pathology, 1996, v. 179, n. 4, p. 370, doi. 10.1002/(SICI)1096-9896(199608)179:4<370::AID-PATH627>3.0.CO;2-N
By:
- ILYAS, M.;
- TOMLINSON, I. P. M.;
- NOVELLI, M. R.;
- HANBY, A.;
- BODMER, W. F.;
- TALBOT, I. C.
Publication type:
Article
A study of genomic instability in early preneoplastic colonic lesions.
Published in:
Oncogene, 2013, v. 32, n. 46, p. 5333, doi. 10.1038/onc.2012.584
By:
- Beggs, A D;
- Domingo, E;
- Abulafi, M;
- Hodgson, S V;
- Tomlinson, I P M
Publication type:
Article
Modifier genes in humans: strategies for identification.
Published in:
European Journal of Human Genetics, 1998, v. 6, n. 1, p. 80, doi. 10.1038/sj.ejhg.5200156
By:
- Houlston, R S;
- Tomlinson, I P M
Publication type:
Article
Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled.
Published in:
British Journal of Surgery, 1997, v. 84, n. 2, p. 233, doi. 10.1046/j.1365-2168.1997.02700.x
By:
- Beck, N. E.;
- Tomlinson, I. P. M.;
- Homfray, T.;
- Hodgson, S. V.;
- Harocopos, C. J.;
- Bodmer, W. F.
Publication type:
Article
The role of cell proliferation and crypt fission in adenoma aggressiveness: a comparison of ileoanal pouch and rectal adenomas in familial adenomatous polyposis.
Published in:
Colorectal Disease, 2011, v. 13, n. 4, p. 387, doi. 10.1111/j.1463-1318.2009.02159.x
By:
- Will, O. C. C.;
- Deheragoda, M.;
- Phillips, R. K. S.;
- Clark, S. K.;
- Tomlinson, I. P. M.
Publication type:
Article
Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden.
Published in:
Nature Communications, 2014, v. 5, n. 10, p. 4809, doi. 10.1038/ncomms5809
By:
- Cazier, J. -B.;
- Rao, S. R.;
- McLean, C. M.;
- Walker, A. K.;
- Wright, B. J.;
- Jaeger, E. E. M.;
- Kartsonaki, C.;
- Marsden, L.;
- Yau, C.;
- Camps, C.;
- Kaisaki, P.;
- Taylor, J.;
- Catto, J. W.;
- Tomlinson, I. P. M.;
- Kiltie, A. E.;
- Hamdy, F. C.
Publication type:
Article
Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden.
Published in:
Nature Communications, 2014, v. 5, n. 6, p. 4264, doi. 10.1038/ncomms5264
By:
- Cazier, J. -B.;
- Rao, S. R.;
- McLean, C. M.;
- Walker, A. L.;
- Wright, B. J.;
- Jaeger, E. E. M.;
- Kartsonaki, C.;
- Marsden, L.;
- Yau, C.;
- Camps, C.;
- Kaisaki, P.;
- Taylor, J.;
- Catto, J. W.;
- Tomlinson, I. P. M.;
- Kiltie, A. E.;
- Hamdy, F. C.
Publication type:
Article
A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.
Published in:
2011
By:
- Abulí, A.;
- Fernández-Rozadilla, C.;
- Giráldez, M. D.;
- Muñoz, J.;
- Gonzalo, V.;
- Bessa, X.;
- Bujanda, L.;
- Reñé, J. M.;
- Lanas, A.;
- García, A. M.;
- Saló, J.;
- Argüello, L.;
- Vilella, À.;
- Carreño, R.;
- Jover, R.;
- Xicola, R. M.;
- Llor, X.;
- Carvajal-Carmona, L.;
- Tomlinson, I. P. M.;
- Kerr, D. J.
Publication type:
journal article
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
Published in:
2010
By:
- Tomlinson, I. P. M.;
- Dunlop, M.;
- Campbell, H.;
- Zanke, B.;
- Gallinger, S.;
- Hudson, T.;
- Koessler, T.;
- Pharoah, P. D.;
- Niittymäkix, I.;
- Tuupanenx, S.;
- Aaltonen, L. A.;
- Hemminki, K.;
- Lindblom, A.;
- Försti, A.;
- Sieber, O.;
- Lipton, L.;
- van Wezel, T.;
- Morreau, H.;
- Wijnen, J. T.;
- Devilee, P.
Publication type:
journal article
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
Published in:
2010
By:
- Tomlinson, I P M;
- Dunlop, M;
- Campbell, H;
- Zanke, B;
- Gallinger, S;
- Hudson, T;
- Koessler, T;
- Pharoah, P D;
- Niittymäki, I;
- Tuupanen, S;
- Aaltonen, L A;
- Hemminki, K;
- Lindblom, A;
- Försti, A;
- Sieber, O;
- Lipton, L;
- van Wezel, T;
- Morreau, H;
- Wijnen, J T;
- Devilee, P
Publication type:
Correction Notice
Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk.
Published in:
2008
By:
- Webb, E.;
- Broderick, P.;
- Chandler, I.;
- Lubbe, S.;
- Penegar, S.;
- Tomlinson, I. P. M.;
- Houlston, R. S.
Publication type:
journal article
The influence of female viability differences on the evolution of mate choice.
Published in:
Heredity, 1996, v. 77, n. 3, p. 303, doi. 10.1038/hdy.1996.144
By:
- Tomlinson, I P M;
- O'Donald, P
Publication type:
Article
Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 10, p. 2212, doi. 10.1038/leu.2012.89
By:
- Enciso-Mora, V;
- Hosking, F J;
- Sheridan, E;
- Kinsey, S E;
- Lightfoot, T;
- Roman, E;
- Irving, J A E;
- Tomlinson, I P M;
- Allan, J M;
- Taylor, M;
- Greaves, M;
- Houlston, R S
Publication type:
Article
Loss of heterozygosity in malignant melanoma at loci on chromosomes 11 and 17 implicated in the pathogenesis of other cancers.
Published in:
Genes, Chromosomes & Cancer, 1993, v. 7, n. 3, p. 169, doi. 10.1002/gcc.2870070310
By:
- Tomlinson, I. P. M.;
- Gammack, A. J.;
- Stickland, J. E.;
- Mann, G. J.;
- Mackie, R. M.;
- Kefford, R. F.;
- McGee, J. O'D.
Publication type:
Article
Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
Published in:
British Journal of Cancer, 2007, v. 96, n. 11, p. 1729, doi. 10.1038/sj.bjc.6603789
By:
- Thirlwell, C.;
- Howarth, K. M.;
- Segditsas, S.;
- Guerra, G.;
- Thomas, H. J. W.;
- Phillips, R. K. S.;
- Talbot, I. C.;
- Gorman, M.;
- Novelli, M. R.;
- Sieber, O. M.;
- Tomlinson, I. P. M.
Publication type:
Article
CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers.
Published in:
British Journal of Cancer, 2001, v. 84, n. 10, p. 1314, doi. 10.1054/bjoc.2001.1800
By:
- Woodford-Richens, K L;
- Halford, S;
- Rowan, A;
- Bevan, S;
- Aaltonen, L A;
- Wasan, H;
- Bicknell, D;
- Bodmer, W F;
- Houlston, R S;
- Tomlinson, I P M
Publication type:
Article
Mutations in Bcl10 are very rare in colorectal cancer.
Published in:
British Journal of Cancer, 1999, v. 80, n. 10, p. 1569, doi. 10.1038/sj.bjc.6690562
By:
- Stone, J G;
- Rowan, A J;
- Tomlinson, I P M;
- Houlston, R S
Publication type:
Article
Allele loss and mutation screen at the Peutz-Jeghers (LKB1) locus (19p13.3) in sporadic ovarian tumours.
Published in:
British Journal of Cancer, 1999, v. 80, n. 1/2, p. 70, doi. 10.1038/sj.bjc.6690323
By:
- Wang, Z-J;
- Churchman, M;
- Campbell, I G;
- Xu, W-H;
- Yan, Z-Y;
- McCluggage, W G;
- Foulkes, W D;
- Tomlinson, I P M
Publication type:
Article
Linkage Analysis of Candidate Regions for Coeliac Disease Genes.
Published in:
Human Molecular Genetics, 1997, v. 6, n. 8, p. 1335, doi. 10.1093/hmg/6.8.1335
By:
- Houlston, R. S.;
- Tomlinson, I. P. M.;
- Ford, D.;
- Seal, S.;
- Marossy, A. M.;
- Ferguson, A.;
- Holmes, G. K. T.;
- Hosie, K. B.;
- Howdle, P. D.;
- Jewell, D. P.;
- Godkin, A.;
- Kerr, G. D.;
- Kumar, P.;
- Logan, R. F. A.;
- Love, A. H. G.;
- Johnston, S.;
- Marsh, M. N.;
- Mitton, S.;
- O'Donoghue, D.;
- Roberts, A.
Publication type:
Article
COGENT (COlorectal Cancer GENeTics): An International Consortium To Study The Role Of Polymorphic Variation On The Risk Of Colorectal Cancer.
Published in:
Asia-Pacific Journal of Oncological Medicine, 2010, v. 2, n. 1, p. 100, doi. 10.5083/apjom.20424965.19
By:
- Tomlinson, I. P. M.;
- Dunlop, M.;
- Campbell, H.;
- Zanke, B.;
- Gallinger, S.;
- Hudson, T.;
- Koessler, T.;
- Pharoah, P. D.;
- Niittymäkix, I.;
- Tuupanenx, S.;
- Aaltonen, L. A.;
- Hemminki, K.;
- Lindblom, A.;
- Försti, A.;
- Sieber, O.;
- Lipton, L.;
- Wezel, T. van;
- Morreau, H.;
- Wijnen, J. T.;
- Devilee, P.
Publication type:
Article

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