Found: 110
Select item for more details and to access through your institution.
Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons.
- Published in:
- Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-03167-5
- By:
- Publication type:
- Article
NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease.
- Published in:
- EMBO Molecular Medicine, 2019, v. 11, n. 4, p. N.PAG, doi. 10.15252/emmm.201809695
- By:
- Publication type:
- Article
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
- Published in:
- EMBO Molecular Medicine, 2018, v. 10, n. 3, p. 1, doi. 10.15252/emmm.201708184
- By:
- Publication type:
- Article
Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 5, p. 1382, doi. 10.1002/anie.201308001
- By:
- Publication type:
- Article
Distinct tau folds initiate templated seeding and alter the post-translational modification profile.
- Published in:
- Brain: A Journal of Neurology, 2023, v. 146, n. 12, p. 4988, doi. 10.1093/brain/awad272
- By:
- Publication type:
- Article
Human tauopathy-derived tau strains determine the substrates recruited for templated amplification.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer's disease mice.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Analysis of Neurons Created from Wild-Type and Alzheimer's Mutation Knock-In Embryonic Stem Cells by a Highly Efficient Differentiation Protocol.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 24, p. 8513, doi. 10.1523/JNEUROSCI.23-24-08513.2003
- By:
- Publication type:
- Article
Presenilins mediate a dual intramembranous ?-secretase cleavage of Notch-1.
- Published in:
- EMBO Journal, 2002, v. 21, n. 20, p. 5408, doi. 10.1093/emboj/cdf541
- By:
- Publication type:
- Article
Production pathway of APP669‐x peptides in the cultured cells.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072184
- By:
- Publication type:
- Article
INPP5D modulates TREM2 loss‐of‐function phenotypes in a β‐amyloidosis mouse model.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073929
- By:
- Publication type:
- Article
INPP5D modulates TREM2 loss‐of‐function phenotypes in a β‐amyloidosis mouse model.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073929
- By:
- Publication type:
- Article
ADAMTS4 as an enzyme cleaving at APP669 site.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.066492
- By:
- Publication type:
- Article
The APP669‐711/Aβ1‐40 ratio as a plasma biomarker specific for the brain Aβ deposition in APP/PS1 mouse.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051555
- By:
- Publication type:
- Article
Identification of ADAMTS4 as an APP‐cleaving enzyme at 669 site in the APP669‐711 production pathway: Biomarkers (non‐neuroimaging)/Plasma/Serum/Urine biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039194
- By:
- Publication type:
- Article
P2‐059: PHOTOOXYGENATION BY BIOCOMPATIBLE CATALYST REDUCES THE Aβ LEVEL IN THE BRAINS OF ALZHEIMER DISEASE MODEL MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P594, doi. 10.1016/j.jalz.2019.06.2466
- By:
- Publication type:
- Article
P3‐197: EFFECT OF GENETIC RISK FACTORS FOR ALZHEIMER DISEASE ON PATHOLOGICAL TAU UPTAKE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1142, doi. 10.1016/j.jalz.2018.06.1555
- By:
- Publication type:
- Article
P1‐200: ANALYSIS OF THE AMYLOID β‐RELATED PEPTIDES IN MOUSE PLASMA AND CELL CULTURE MEDIA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P356, doi. 10.1016/j.jalz.2018.06.204
- By:
- Publication type:
- Article
Specific Mutations in Aph1 Cause γ-Secretase Activation.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 507, doi. 10.3390/ijms23010507
- By:
- Publication type:
- Article
Promotion in the Clearance of Aggregated Aβ In Vivo Using Amyloid Selective Photo-Oxygenation Technology.
- Published in:
- Neuroscience Insights, 2022, p. 1, doi. 10.1177/26331055221126179
- By:
- Publication type:
- Article
Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical Neurons.
- Published in:
- eNeuro, 2021, v. 8, n. 2, p. 1, doi. 10.1523/ENEURO.0500-20.2021
- By:
- Publication type:
- Article
The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 3, p. 130, doi. 10.1107/S2053230X17001911
- By:
- Publication type:
- Article
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
- Published in:
- EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2023114272
- By:
- Publication type:
- Article
GENOMEWIDE SCREENING OF MOLECULES INVOLVED IN UPTAKE OF ALZHEIMER DISEASE-ASSOCIATED PROTEINS BY CRIPSR/CAS9 SYSTEM.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P996, doi. 10.1016/j.jalz.2017.06.1374
- By:
- Publication type:
- Article
THE INHIBITORY EFFECT OF MEMANTINE ON THE PRODUCTION OF ABETA PEPTIDES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1041, doi. 10.1016/j.jalz.2016.06.2162
- By:
- Publication type:
- Article
PARTIAL LOSS OF PICALM PREDOMINANTLY AFFECTS THE AMYLOID-BETA DEPOSITION IN THE PIRIFORM CORTEX OF MOUSE MODEL OF ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1030, doi. 10.1016/j.jalz.2016.06.2130
- By:
- Publication type:
- Article
Pathophysiological impact of astrocyte-derived kallikrein-related peptidase 7 on Aβ metabolism in brain.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P504, doi. 10.1016/j.jalz.2015.06.594
- By:
- Publication type:
- Article
PICALM regulates Aβ42 production by modulation of gamma-secretase trafficking
- Published in:
- 2012
- By:
- Publication type:
- Abstract
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Molecular mechanism of action of gamma-secretase inhibitors and modulators
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Intrabody against immature nicastrin disrupts the proper folding and the glycosyl maturation of the extracellular domain of nicastrin
- Published in:
- 2009
- By:
- Publication type:
- Abstract
Three dimensional structure of signal peptide peptidase
- Published in:
- 2009
- By:
- Publication type:
- Abstract
Single chain variable fragment against nicastrin inhibits the γ-secretase activity
- Published in:
- 2009
- By:
- Publication type:
- Abstract
P4-211: The functional roles of transmembrane domains of presenilin 1 in the formation of active gamma-secretase complex
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P4-208: Transmembrane domain 1 of presenilin 1 contributes to the formation of the catalytic pore of gamma-secretase
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P4-207: Chemical biological analysis of gamma-secretase using arylsulfonamide-type inhibitors
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P3-348: Neuron-specific regulation of beta-secretase activity by sphingosine kinase
- Published in:
- 2008
- By:
- Publication type:
- Abstract
O4-03-03: C-terminal PAL motif of presenilin 1 comprises the subsite of gamma-secretase within the catalytic pore
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P3-416: Probing the structural changes of presenilin 1 by substituted-cysteine accessibility method
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-412: Generation of monoclonal antibodies against the extracellular domain of nicastrin
- Published in:
- 2006
- By:
- Publication type:
- Abstract
O1-02-07: Different actions of dipeptidic compounds on presenilins define the enzyme specificity of γ-secretase inhibitor
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-416: Probing the structural changes of presenilin 1 by substituted-cysteine accessibility method
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P3-412: Generation of monoclonal antibodies against the extracellular domain of nicastrin
- Published in:
- 2006
- By:
- Publication type:
- Abstract
O1-02-07: Different actions of dipeptidic compounds on presenilins define the enzyme specificity of γ-secretase inhibitor
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Experimental detection of proteolytic activity in a signal peptide peptidase of Arabidopsis thaliana.
- Published in:
- BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-16
- By:
- Publication type:
- Article
Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation.
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 5, p. 1406, doi. 10.1002/ange.201308001
- By:
- Publication type:
- Article
Cell-free methods to produce structurally intact mammalian membrane proteins.
- Published in:
- Scientific Reports, 2016, p. 30442, doi. 10.1038/srep30442
- By:
- Publication type:
- Article
A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.
- Published in:
- Scientific Reports, 2016, p. 23969, doi. 10.1038/srep23969
- By:
- Publication type:
- Article
Molecular basis promoting centriole triplet microtubule assembly.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46454-x
- By:
- Publication type:
- Article
γ-Secretase Pharmacology: What Pharmacology Will Work for Alzheimer's Disease?
- Published in:
- 2013
- By:
- Publication type:
- Journal Article