Works by Tomaszewski, Joseph

Results: 29

Interspecies pharmacokinetics and in vitro metabolism of SQ109.

Published in:

2006

By:

Jia, Lee;
Noker, Patricia E;
Coward, Lori;
Gorman, Gregory S.;
Protopopova, Marina;
Tomaszewski, Joseph E.

Publication type:

journal article

Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug.

Published in:

British Journal of Pharmacology, 2005, v. 144, n. 1, p. 80, doi. 10.1038/sj.bjp.0705984

By:

Lee Jia;
Tomaszewski, Joseph E.;
Hanrahan, Colleen;
Coward, Lori;
Noker, Patricia;
Gorman, Gregory;
Nikonenko, Boris;
Protopopova, Marina

Publication type:

Article

Notch1 phenotype and clinical stage progression in non-small cell lung cancer.

Published in:

Journal of Hematology & Oncology, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13045-014-0104-2

By:

Nguyen, Dat;
Rubinstein, Larry;
Takebe, Naoko;
Miele, Lucio;
Tomaszewski, Joseph E.;
Ivy, Percy;
Doroshow, James H.;
Yang, Sherry X.

Publication type:

Article

Indolo-pyrido-isoquinolin based alkaloid inhibits growth, invasion and migration of breast cancer cells via activation of p53-miR34a axis.

Published in:

Molecular Oncology, 2016, v. 10, n. 7, p. 1118, doi. 10.1016/j.molonc.2016.04.003

By:

Avtanski, Dimiter B.;
Nagalingam, Arumugam;
Tomaszewski, Joseph E.;
Risbood, Prabhakar;
Difillippantonio, Michael J.;
Saxena, Neeraj K.;
Malhotra, Sanjay V.;
Sharma, Dipali

Publication type:

Article

Clinical and pharmacologic evaluation of two dosing schedules of indotecan (LMP400), a novel indenoisoquinoline, in patients with advanced solid tumors.

Published in:

2016

By:

Kummar, Shivaani;
Chen, Alice;
Gutierrez, Martin;
Pfister, Thomas;
Wang, Lihua;
Redon, Christophe;
Bonner, William;
Yutzy, William;
Zhang, Yiping;
Kinders, Robert;
Ji, Jiuping;
Allen, Deborah;
Covey, Joseph;
Eiseman, Julie;
Holleran, Julianne;
Beumer, Jan;
Rubinstein, Larry;
Collins, Jerry;
Tomaszewski, Joseph;
Parchment, Ralph

Publication type:

journal article

Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 3, p. 777, doi. 10.1007/s00280-010-1517-4

By:

Reid, Joel;
Buhrow, Sarah;
Kuffel, Mary;
Jia, Lee;
Spanswick, Victoria;
Hartley, John;
Thurston, David;
Tomaszewski, Joseph;
Ames, Matthew

Publication type:

Article

Preclinical pharmacokinetic, toxicological and biomarker evaluation of SR16157, a novel dual-acting steroid sulfatase inhibitor and selective estrogen receptor modulator.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 6, p. 1341, doi. 10.1007/s00280-010-1430-x

By:

Rausch, Linda;
Green, Carol;
Steinmetz, Karen;
LeValley, Sue;
Catz, Paul;
Zaveri, Nurulain;
Schweikart, Karen;
Tomaszewski, Joseph;
Mirsalis, Jon

Publication type:

Article

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Published in:

2010

By:

Behrsing HP;
Furniss MJ;
Robillard KA;
Tomaszewski JE;
Parchment RE;
Behrsing, Holger Peter;
Furniss, Michael J;
Robillard, Kristine A;
Tomaszewski, Joseph E;
Parchment, Ralph E

Publication type:

journal article

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 6, p. 1083, doi. 10.1007/s00280-009-1113-7

By:

Behrsing, Holger Peter;
Furniss, Michael J.;
Robillard, Kristine A.;
Tomaszewski, Joseph E.;
Parchment, Ralph E.

Publication type:

Article

Lack of toxicity of a STAT3 decoy oligonucleotide.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 63, n. 6, p. 983, doi. 10.1007/s00280-008-0823-6

By:

Sen, Malabika;
Tosca, Patricia J.;
Zwayer, Christa;
Ryan, Michael J.;
Johnson, Jerry D.;
Knostman, Katherine A. B.;
Giclas, Patricia C.;
Peggins, James O.;
Tomaszewski, Joseph E.;
McMurray, Timothy P.;
Changyou Li;
Leibowitz, Michael S.;
Ferris, Robert L.;
Gooding, William E.;
Thomas, Sufi M.;
Johnson, Daniel E.;
Grandis, Jennifer R.

Publication type:

Article

Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 6, p. 637, doi. 10.1007/s00280-005-1000-9

By:

Glaze, Elizabeth R.;
Lambert, Amy L.;
Smith, Adaline C.;
Page, John G.;
Johnson, William D.;
McCormick, David L.;
Brown, Alan P.;
Levine, Barry S.;
Covey, Joseph M.;
Egorin, Merrill J.;
Eiseman, Julie L.;
Holleran, Julianne L.;
Sausville, Edward A.;
Tomaszewski, Joseph E.

Publication type:

Article

Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 51, n. 3, p. 193, doi. 10.1007/s00280-002-0553-0

By:

Mirsalis, Jon C.;
Schindler-Horvat, Janice;
Hill, James R.;
Green, Carol E.;
Mitoma, Chozo;
Tomaszewski, Joseph E.;
Tyson, Charles A.;
Donohue, Susan J.

Publication type:

Article

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171582

By:

Ji, Jiuping;
Zhang, Yiping;
Redon, Christophe E.;
Reinhold, William C.;
Chen, Alice P.;
Fogli, Laura K.;
Holbeck, Susan L.;
Parchment, Ralph E.;
Hollingshead, Melinda;
Tomaszewski, Joseph E.;
Dudon, Quentin;
Pommier, Yves;
Doroshow, James H.;
Bonner, William M.

Publication type:

Article

Short-term Toxicity Study of ST-20 (NSC-741804) by Oral Gavage in Sprague-Dawley Rats.

Published in:

Toxicologic Pathology, 2011, v. 39, n. 4, p. 614, doi. 10.1177/0192623311406933

By:

TERSE, PRAMOD S.;
JOHNSON, JERRY D.;
HAWK, MICHAEL A.;
RITCHIE, GLENN D.;
RYAN, MICHAEL J.;
VASCONCELOS, DAPHNE Y.;
CONTOS, DENISE A.;
PERRINE, SUSAN P.;
PEGGINS, JAMES O.;
TOMASZEWSKI, JOSEPH E.

Publication type:

Article

A recombinant vaccinia virus expressing human prostate-specific antigen (PSA): Safety and immunogenicity in a non-human primate.

Published in:

International Journal of Cancer, 1995, v. 63, n. 2, p. 231, doi. 10.1002/ijc.2910630215

By:

Hodge, James W.;
Schlom, Jeffrey;
Donohue, Susan J.;
Tomaszewski, Joseph E.;
Wheeler, Clyde W.;
Levine, Barry S.;
Gritz, Linda;
Panicali, Dennis;
Kantor, Judy A.

Publication type:

Article

Antibody-independent capture of circulating tumor cells of non-epithelial origin with the ApoStream<sup>®</sup> system.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0175414

By:

Balasubramanian, Priya;
Kinders, Robert J.;
Kummar, Shivaani;
Gupta, Vishal;
Hasegawa, David;
Menachery, Anoop;
Lawrence, Scott M.;
Wang, Lihua;
Ferry-Galow, Katherine;
Davis, Darren;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography/mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2003, v. 17, n. 18, p. 2089, doi. 10.1002/rcm.1155

By:

Cheng, Xun;
Shin, Young Geun;
Levine, Barry S.;
Smith, Adaline C.;
Tomaszewski, Joseph E.;
van Breemen, Richard B.

Publication type:

Article

Vaccination with a recombinant vaccinia vaccine containing the B7-1 co-stimulatory molecule causes no significant toxicity and enhances T cell-mediated cytotoxicity.

Published in:

International Journal of Cancer, 2000, v. 85, n. 4, p. 508, doi. 10.1002/(SICI)1097-0215(20000215)85:4<508::AID-IJC11>3.0.CO;2-D

By:

Freund, Yvonne R.;
Mirsalis, Jon C.;
Fairchild, David G.;
Brune, Joyce;
Hokama, Leslie A.;
Schindler-Horvat, Janice;
Tomaszewski, Joseph E.;
Hodge, James W.;
Schlom, Jeffrey;
Kantor, Judy A.;
Tyson, Charles A.;
Donohue, Susan J.

Publication type:

Article

Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.

Published in:

Cell Cycle, 2011, v. 10, n. 23, p. 4074, doi. 10.4161/cc.10.23.18170

By:

Nguyen, Diana;
Zajac-Kaye, Maria;
Rubinstein, Larry;
Voeller, Donna;
Tomaszewski, Joseph E.;
Kummar, Shivaani;
Chen, Alice P.;
Pommier, Yves;
Doroshow, James H.;
Yang, Sherry X.

Publication type:

Article

The statistics of phase 0 trials.

Published in:

Statistics in Medicine, 2010, v. 29, n. 10, p. 1072, doi. 10.1002/sim.3840

By:

Rubinstein, Larry V.;
Steinberg, Seth M.;
Kummar, Shivaani;
Kinders, Robert;
Parchment, Ralph E.;
Murgo, Anthony J.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile.

Published in:

Investigational New Drugs, 2018, v. 36, n. 2, p. 230, doi. 10.1007/s10637-017-0495-3

By:

Speranza, Giovanna;
Anderson, Larry;
Chen, Alice P.;
Do, Khanh;
Eugeni, Michelle;
Weil, Marcie;
Rubinstein, Larry;
Majerova, Eva;
Collins, Jerry;
Horneffer, Yvonne;
Juwara, Lamin;
Zlott, Jennifer;
Bishop, Rachel;
Conley, Barbara A.;
Streicher, Howard;
Tomaszewski, Joseph;
Doroshow, James H.;
Kummar, Shivaani

Publication type:

Article

In Vitro Exposure of Precision-Cut Lung Slices to 2-(4-Amino-3-Methylphenyl)-5-Fluorobenzothiazole Lysylamide Dihydrochloride (NSC 710305, Phortress) Increases Inflammatory Cytokine Content and Tissue Damage.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 470, doi. 10.1093/toxsci/kfs319

By:

Behrsing, Holger P.;
Furniss, Michael J.;
Davis, Myrtle;
Tomaszewski, Joseph E.;
Parchment, Ralph E.

Publication type:

Article

In Vitro Human Tissue Models in Risk Assessment: Report of a Consensus-Building Workshop.

Published in:

Toxicological Sciences, 2001, v. 59, n. 1, p. 17, doi. 10.1093/toxsci/59.1.17

By:

MacGregor, James T.;
Collins, Jerry M.;
Sugiyama, Yuichi;
Tyson, Charles A.;
Dean, Jack;
Smith, Lewis;
Andersen, Melvin;
Curren, Rodger D.;
Houston, J. Brian;
Kadlubar, Fred F.;
Kedderis, Gregory L.;
Krishnan, Kannan;
Li, Albert P.;
Parchment, Ralph E.;
Thummel, Kenneth;
Tomaszewski, Joseph E.;
Ulrich, Roger;
Vickers, Alison E. M.;
Wrighton, Steven A.

Publication type:

Article

Compressing drug development timelines in oncology using phase '0' trials.

Published in:

2007

By:

Kummar, Shivaani;
Kinders, Robert;
Rubinstein, Larry;
Parchment, Ralph E.;
Murgo, Anthony J.;
Collins, Jerry;
Pickeral, Oxana;
Low, Jennifer;
Steinberg, Seth M.;
Gutierrez, Martin;
Yang, Sherry;
Helman, Lee;
Wiltrout, Robert;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

review

Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199361

By:

Navas, Tony;
Pfister, Thomas D.;
Colantonio, Simona;
Aziz, Amina;
Dieckman, Lynda;
Saul, Richard G.;
Kaczmarczyk, Jan;
Borgel, Suzanne;
Alcoser, Sergio Y.;
Hollingshead, Melinda G.;
Lee, Young H.;
Bottaro, Donald P.;
Hiltke, Tara;
Whiteley, Gordon;
Takebe, Naoko;
Kinders, Robert J.;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Pharmacokinetics and pharmacodynamics of Phor21-βCG(ala), a lytic peptide conjugate.

Published in:

Journal of Pharmacy & Pharmacology, 2008, v. 60, n. 11, p. 1441, doi. 10.1211/jpp.60.11.0004

By:

Lee Jia;
Patricia E. Noker;
Gary A. Piazza;
Carola Leuschner;
William Hansel;
Gregory S. Gorman;
Lori U. Coward;
Joseph Tomaszewski

Publication type:

Article

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements.

Published in:

2010

By:

Kummar, Shivanni;
Chen, Helen X.;
Wright, John;
Holbeck, Susan;
Millin, Myrtle Davis;
Tomaszewski, Joseph;
Zweibel, James;
Collins, Jerry;
Doroshow, James H.

Publication type:

review

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050494

By:

Pfister, Thomas D.;
Hollingshead, Melinda;
Kinders, Robert J.;
Zhang, Yiping;
Evrard, Yvonne A.;
Ji, Jiuping;
Khin, Sonny A.;
Borgel, Suzanne;
Stotler, Howard;
Carter, John;
Divelbiss, Raymond;
Kummar, Shivaani;
Pommier, Yves;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Modeling Pharmacodynamic Response to the Poly(ADPRibose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026152

By:

Ji, Jiuping;
Kinders, Robert J.;
Zhang, Yiping;
Rubinstein, Larry;
Kummar, Shivaani;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article