Works matching AU Todd, Matthew H.

Results: 32

Synthesis and Evaluation of 1,8-Disubstituted-Cyclam/Naphthalimide Conjugates as Probes for Metal Ions.

Published in:

ChemistryOpen, 2016, v. 5, n. 4, p. 375, doi. 10.1002/open.201600010

By:

Wong, Joseph K. ‐ H.;
Ast, Sandra;
Yu, MingfENg;
Flehr, Roman;
Counsell, Andrew J.;
Turner, Peter;
Crisologo, Patrick;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

Incorporation of Bulky and Cationic Cyclam‐Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity.

Published in:

ChemistryOpen, 2013, v. 2, n. 3, p. 99, doi. 10.1002/open.201300014

By:

Yu, Mingfeng;
Lim, Ngee H.;
Ellis, Samantha;
Nagase, Hideaki;
Triccas, James A.;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Open science is a research accelerator.

Published in:

2011

By:

Woelfle, Michael;
Olliaro, Piero;
Todd, Matthew H.

Publication type:

Opinion

Reversing the Triazole Topology in a Cyclam-Triazole-Dye Ligand Gives a 10-Fold Brighter Signal Response to Zn<sup>2+</sup> in Aqueous Solution.

Published in:

European Journal of Inorganic Chemistry, 2012, v. 2012, n. 34, p. 5611, doi. 10.1002/ejic.201201072

By:

Ast, Sandra;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Identification of Dihydropyrazolo[1,5- a ]pyrazin-4(5 H)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 7, p. 836, doi. 10.3390/ph17070836

By:

Ghoshal, Anirban;
Magalhães, Álvaro F.;
Asressu, Kesatebrhan Haile;
Hossain, Mohammad Anwar;
Todd, Matthew H.;
Willson, Timothy M.

Publication type:

Article

An open source pharma roadmap.

Published in:

2017

By:

Balasegaram, Manica;
Kolb, Peter;
McKew, John;
Menon, Jaykumar;
Olliaro, Piero;
Sablinski, Tomasz;
Thomas, Zakir;
Todd, Matthew H.;
Torreele, Els;
Wilbanks, John

Publication type:

journal article

Selective Displacement of a Scorpionand Triazole Ligand from Metallocyclam Complexes Visualised with NMR Spectroscopy.

Published in:

European Journal of Inorganic Chemistry, 2017, v. 2017, n. 7, p. 1075, doi. 10.1002/ejic.201601474

By:

Wong, Joseph K.‐H.;
Proschogo, Nicholas;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

Using Click Chemistry to Tune the Properties and the Fluorescence Response Mechanism of Structurally Similar Probes for Metal Ions.

Published in:

European Journal of Inorganic Chemistry, 2015, v. 2015, n. 1, p. 58, doi. 10.1002/ejic.201402811

By:

Ast, Sandra;
Kuke, Stefanie;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Resolution of Praziquantel.

Published in:

PLoS Neglected Tropical Diseases, 2011, v. 5, n. 9, p. 1, doi. 10.1371/journal.pntd.0001260

By:

Woelfle, Michael;
Seerden, Jean-Paul;
de Gooijer, Jesse;
Pouwer, Kees;
Olliaro, Piero;
Todd, Matthew H.

Publication type:

Article

Resolution of Praziquantel.

Published in:

PLoS Neglected Tropical Diseases, 2011, v. 5, n. 9, p. 1, doi. 10.1371/journal.pntd.0001260

By:

Woelfle, Michael;
Seerden, Jean-Paul;
Gooijer, Jesse de;
Pouwer, Kees;
Olliaro, Piero;
Todd, Matthew H.

Publication type:

Article

A Kernel for Open Source Drug Discovery in Tropical Diseases.

Published in:

PLoS Neglected Tropical Diseases, 2009, v. 3, n. 4, p. 1, doi. 10.1371/journal.pntd.0000418

By:

Ortí, Leticia;
Carbajo, Rodrigo J.;
Pieper, Ursula;
Eswar, Narayanan;
Maurer, Stephen M.;
Rai, Arti K.;
Taylor, Ginger;
Todd, Matthew H.;
Pineda-Lucena, Antonio;
Sali, Andrej;
Marti-Renom, Marc A.

Publication type:

Article

A Kernel for Open Source Drug Discovery in Tropical Diseases.

Published in:

PLoS Neglected Tropical Diseases, 2009, v. 3, n. 4, p. 1, doi. 10.1371/journal.pntd.0000418

By:

Ortí, Leticia;
Carbajo, Rodrigo J.;
Pieper, Ursula;
Eswar, Narayanan;
Maurer, Stephen M.;
Rai, Arti K.;
Taylor, Ginger;
Todd, Matthew H.;
Pineda-Lucena, Antonio;
Sali, Andrej;
Marti-Renom, Marc A.

Publication type:

Article

Molecular Switches for any pH: A Systematic Study of the Versatile Coordination Behaviour of Cyclam Scorpionands.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 7, p. 1573, doi. 10.1002/chem.201703488

By:

Lau, Yu Heng;
Clegg, Jack K.;
Price, Jason R.;
Macquart, Rene B.;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

N-Aryl Groups Are Ubiquitous in Cross-Dehydrogenative Couplings Because They Stabilize Reactive Intermediates.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 39, p. 9313, doi. 10.1002/chem.201700430

By:

Tsang, Althea S.‐K.;
Hashmi, A. Stephen K.;
Comba, Peter;
Kerscher, Marion;
Chan, Bun;
Todd, Matthew H.

Publication type:

Article

A Fluorescent 'Allosteric Scorpionand' Complex Visualizes a Biological Recognition Event.

Published in:

ChemBioChem, 2013, v. 14, n. 2, p. 224, doi. 10.1002/cbic.201200637

By:

Yu, Mingfeng;
Yu, Qun;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Neuroprotective peptide–macrocycle conjugates reveal complex structure–activity relationships in their interactions with amyloid β.

Published in:

Metallomics, 2014, v. 6, n. 10, p. 1931, doi. 10.1039/c4mt00122b

By:

Yu, Mingfeng;
Ryan, Timothy M.;
Ellis, Samantha;
Bush, Ashley I.;
Triccas, James A.;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Six Laws of Open Source Drug Discovery.

Published in:

ChemMedChem, 2019, v. 14, n. 21, p. 1804, doi. 10.1002/cmdc.201900565

By:

Todd, Matthew H.

Publication type:

Article

Ten Simple Rules for Cultivating Open Science and Collaborative R&D.

Published in:

2013

By:

Masum, Hassan;
Rao, Aarthi;
Good, Benjamin M.;
Todd, Matthew H.;
Edwards, Aled M.;
Chan, Leslie;
Bunin, Barry A.;
Su, Andrew I.;
Thomas, Zakir;
Bourne, Philip E.

Publication type:

Editorial

A Click Fluorophore Sensor that Can Distinguish Cu.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 10, p. 2850, doi. 10.1002/chem.201002477

By:

Lau, Yu Heng;
Price, Jason R.;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

The First Catalytic, Enantioselective Aza-Henry Reaction of an Unactivated Cyclic Imine.

Published in:

Advanced Synthesis & Catalysis, 2012, v. 354, n. 16, p. 2954, doi. 10.1002/adsc.201200558

By:

Amarasinghe, Nilupa R.;
Turner, Peter;
Todd, Matthew H.

Publication type:

Article

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 4, p. 1, doi. 10.1371/journal.pntd.0006437

By:

Lim, Wilson;
Melse, Youri;
Konings, Mickey;
Phat Duong, Hung;
Eadie, Kimberly;
Laleu, Benoît;
Perry, Ben;
Todd, Matthew H.;
Ioset, Jean-Robert;
van de Sande, Wendy W. J.

Publication type:

Article

Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in Open Science.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0111782

By:

Badiola, Katrina A.;
Quan, Diana H.;
Triccas, James A.;
Todd, Matthew H.

Publication type:

Article

Incorporating a Piperidinyl Group in the Fluorophore Extends the Fluorescence Lifetime of Click-Derived Cyclam-Naphthalimide Conjugates.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100761

By:

Yu, Mingfeng;
Ast, Sandra;
Yu, Qun;
Lo, Anthony T. S.;
Flehr, Roman;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

The Outcome of the Oxidations of Unusual Enediamide Motifs Is Governed by the Stabilities of the Intermediate Iminium Ions.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047224

By:

Ahamed, Muneer;
Chan, Bun;
Jensen, Paul;
Todd, Matthew H.

Publication type:

Article

Synthesis and Antiangiogenic Activity of N-Alkylated Levamisole Derivatives.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045405

By:

Hansen, Anders N.;
Bendiksen, Christine D.;
Sylvest, Lene;
Friis, Tina;
Staerk, Dan;
Jørgensen, Flemming Steen;
Olsen, Christian A.;
Houen, Gunnar;
Todd, Matthew H.

Publication type:

Article

Polyamide-Scorpion Cyclam Lexitropsins Selectively Bind AT-Rich DNA Independently of the Nature of the Coordinated Metal.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0017446

By:

Lo, Anthony T. S.;
Salam, Noeris K.;
Hibbs, David E.;
Rutledge, Peter J.;
Todd, Matthew H.

Publication type:

Article

Responsive Metal Complexes: A Click-Based 'Allosteric Scorpionate' Complex Permits the Detection of a Biological Recognition Event by EPR/ENDOR Spectroscopy.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 15, p. 3720, doi. 10.1002/chem.200802425

By:

Tamanini, Emiliano;
Rigby, Stephen E. J.;
Motevalli, Majid;
Todd, Matthew H.;
Watkinson, Michael

Publication type:

Article

Open source drug discovery – A limited tutorial.

Published in:

Parasitology, 2014, v. 141, n. 1, p. 148, doi. 10.1017/S0031182013001121

By:

ROBERTSON, MURRAY N.;
YLIOJA, PAUL M.;
WILLIAMSON, ALICE E.;
WOELFLE, MICHAEL;
ROBINS, MICHAEL;
BADIOLA, KATRINA A.;
WILLIS, PAUL;
OLLIARO, PIERO;
WELLS, TIMOTHY N. C.;
TODD, MATTHEW H.;
Barrett, Michael P.;
Croft, Simon L.

Publication type:

Article

Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01035

By:

Munawar, Saba;
Windley, Monique J.;
Tse, Edwin G.;
Todd, Matthew H.;
Hill, Adam P.;
Vandenberg, Jamie I.;
Jabeen, Ishrat

Publication type:

Article

Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing.

Published in:

Molecules, 2017, v. 22, n. 2, p. 200, doi. 10.3390/molecules22020200

By:

Wong, Joseph K.-H.;
Todd, Matthew H.;
Rutledge, Peter J.

Publication type:

Article

A kernel for the Tropical Disease Initiative.

Published in:

2009

By:

Ortí, Leticia;
Carbajo, Rodrigo J;
Pieper, Ursula;
Eswar, Narayanan;
Maurer, Stephen M;
Rai, Arti K;
Taylor, Ginger;
Todd, Matthew H;
Pineda-Lucena, Antonio;
Sali, Andrej;
Marti-Renom, Marc A

Publication type:

Letter

The past, present and future of anti-malarial medicines.

Published in:

Malaria Journal, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12936-019-2724-z

By:

Tse, Edwin G.;
Korsik, Marat;
Todd, Matthew H.

Publication type:

Article