Works matching AU Timmusk, Tõnis

Results: 37

AP-1 Transcription Factors Mediate BDNF-Positive Feedback Loop in Cortical Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 4, p. 1290, doi. 10.1523/JNEUROSCI.3360-15.2016

By:

Tuvikene, Jürgen;
Pruunsild, Priit;
Orav, Ester;
Esvald, Eli-Eelika;
Timmusk, Tõnis

Publication type:

Article

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.

Published in:

Nature, 2007, v. 448, n. 7149, p. 73, doi. 10.1038/nature05957

By:

Lindholm, Päivi;
Voutilainen, Merja H.;
Laurén, Juha;
Peränen, Johan;
Leppänen, Veli-Matti;
Andressoo, Jaan-Olle;
Lindahl, Maria;
Janhunen, Sanna;
Kalkkinen, Nisse;
Timmusk, Tõnis;
Tuominen, Raimo K.;
Saarma, Mart

Publication type:

Article

Revisiting the expression of BDNF and its receptors in mammalian development.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1182499

By:

Esvald, Eli-Eelika;
Tuvikene, Jürgen;
Kiir, Carl Sander;
Avarlaid, Annela;
Tamberg, Laura;
Sirp, Alex;
Shubina, Anastassia;
Cabrera-Cabrera, Florencia;
Pihlak, Arno;
Koppel, Indrek;
Palm, Kaia;
Timmusk, Tõnis

Publication type:

Article

PCSK9 deficiency alters brain lipid composition without affecting brain development and function.

Published in:

Frontiers in Molecular Neuroscience, 2023, v. 15, p. 1, doi. 10.3389/fnmol.2022.1084633

By:

Pärn, Angela;
Olsen, Ditte;
Tuvikene, Jürgen;
Kaas, Mathias;
Borisova, Ekaterina;
Bilgin, Mesut;
Elhauge, Mie;
Vilstrup, Joachim;
Madsen, Peder;
Ambrozkiewicz, Mateusz C.;
Goz, Roman U.;
Timmusk, Tõnis;
Tarabykin, Victor;
Gustafsen, Camilla;
Glerup, Simon

Publication type:

Article

Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues.

Published in:

Frontiers in Molecular Neuroscience, 2022, v. 15, p. 01, doi. 10.3389/fnmol.2022.1033224

By:

Sirp, Alex;
Shubina, Anastassia;
Tuvikene, Jürgen;
Tamberg, Laura;
Kiir, Carl Sander;
Kranich, Laura;
Timmusk, Tõnis

Publication type:

Article

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.

Published in:

Nature Genetics, 2003, v. 35, n. 1, p. 76, doi. 10.1038/ng1219

By:

Zuccato, Chiara;
Tartan, Marzia;
Crotti, Andrea;
Goifredo, Donato;
Valenza, Marta;
Conti, Luciano;
Cataudella, Tiziana;
Leavitt, Blair R.;
Hayden, Michael R.;
Timmusk, Tõnis;
Rigamonti, Dorotea;
Cattaneo, Elena

Publication type:

Article

Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-20849-6

By:

Jaago, Mariliis;
Rähni, Annika;
Pupina, Nadežda;
Pihlak, Arno;
Sadam, Helle;
Tuvikene, Jürgen;
Avarlaid, Annela;
Planken, Anu;
Planken, Margus;
Haring, Liina;
Vasar, Eero;
Baćević, Miljana;
Lambert, France;
Kalso, Eija;
Pussinen, Pirkko;
Tienari, Pentti J.;
Vaheri, Antti;
Lindholm, Dan;
Timmusk, Tõnis;
Ghaemmaghami, Amir M.

Publication type:

Article

Stimulus-Dependent Expression of Bdnf Is Mediated by ATF2, MYT1L, and EGR1 Transcription Factors.

Published in:

Journal of Neuroscience, 2025, v. 45, n. 12, p. 1, doi. 10.1523/JNEUROSCI.0313-24.2025

By:

Esvald, Eli-Eelika;
Moistus, Andra;
Lehe, Karin;
Avarlaid, Annela;
Šubina, Anastassia;
Kuusemets, Liis;
Tuvikene, Jürgen;
Timmusk, Tõnis

Publication type:

Article

Differential Regulation of the BDNF Gene in Cortical and Hippocampal Neurons.

Published in:

Journal of Neuroscience, 2022, v. 42, n. 49, p. 9110, doi. 10.1523/JNEUROSCI.2535-21.2022

By:

Esvald, Eli-Eelika;
Tuvikene, Jürgen;
Moistus, Andra;
Rannaste, Käthy;
Kõomägi, Susann;
Timmusk, Tõnis

Publication type:

Article

Dopamine cross-reacts with adrenoreceptors in cortical astrocytes to induce BDNF expression, CREB signaling and morphological transformation.

Published in:

Glia (0894-1491), 2018, v. 66, n. 1, p. 206, doi. 10.1002/glia.23238

By:

Koppel, Indrek;
Jaanson, Kaur;
Klasche, Airi;
Tuvikene, Jürgen;
Tiirik, Tõnis;
Pärn, Angela;
Timmusk, Tõnis

Publication type:

Article

Intronic enhancer region governs transcript-specific Bdnf expression in rodent neurons.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65161

By:

Tuvikene, Jürgen;
Esvald, Eli-Eelika;
Rähni, Annika;
Uustalu, Kaie;
Zhuravskaya, Anna;
Avarlaid, Annela;
Makeyev, Eugene V.;
Timmusk, Tõnis

Publication type:

Article

Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters.

Published in:

European Journal of Neuroscience, 1994, v. 6, n. 4, p. 587, doi. 10.1111/j.1460-9568.1994.tb00303.x

By:

Kokaia, Zaal;
Metsis, Madis;
Kokaia, Merab;
Bengzon, Johan;
Elmér, Eskil;
Smith, Maj-Lis;
Timmusk, Tõnis;
Siesjö, Bo K.;
Persson, Håkan;
Lindvall, Olle

Publication type:

Article

Widespread and Developmentally Regulated Expression of Neurotrophin-4 mRNA in Rat Brain and Peripheral Tissues.

Published in:

European Journal of Neuroscience, 1993, v. 5, n. 6, p. 605, doi. 10.1111/j.1460-9568.1993.tb00526.x

By:

Timmusk, Tõnis;
Belluardo, Natale;
Metsis, Madis;
Persson, Håkan

Publication type:

Article

Identification of cis-Elements and Transcription Factors Regulating Neuronal Activity-Dependent Transcription of Human BDNF Gene.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 9, p. 3295, doi. 10.1523/JNEUROSCI.4540-10.2011

By:

Pruunsild, Priit;
Sepp, Mari;
Orav, Ester;
Koppel, Indrek;
Timmusk, Tõnis

Publication type:

Article

Nuclear Factor of Activated T-Cells Isoform c4(NFATc4/NFAT3) as a Mediator of Antiapoptotic Transcription in NMDA Receptor-Stimulated Cortical Neurons.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 48, p. 15331, doi. 10.1523/JNEUROSCI.4873-09.2009

By:

Vashishta, Aruna;
Habas, Agata;
Pruunsild, Priit;
Jing-Juan Zheng;
Timmusk, Tõnis;
Hetman, Michal

Publication type:

Article

Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43069-x

By:

Taal, Kati;
Tuvikene, Jürgen;
Rullinkov, Grete;
Piirsoo, Marko;
Sepp, Mari;
Neuman, Toomas;
Tamme, Richard;
Timmusk, Tõnis

Publication type:

Article

Altered Expression Profile of IgLON Family of Neural Cell Adhesion Molecules in the Dorsolateral Prefrontal Cortex of Schizophrenic Patients.

Published in:

Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00008

By:

Karis, Karina;
Eskla, Kattri-Liis;
Kaare, Maria;
Täht, Karin;
Tuusov, Jana;
Visnapuu, Tanel;
Innos, Jürgen;
Jayaram, Mohan;
Timmusk, Tõnis;
Weickert, Cynthia S.;
Väli, Marika;
Vasar, Eero;
Philips, Mari-Anne

Publication type:

Article

Regulation of different human NFAT isoforms by neuronal activity.

Published in:

Journal of Neurochemistry, 2016, v. 137, n. 3, p. 394, doi. 10.1111/jnc.13568

By:

Vihma, Hanna;
Luhakooder, Mirjam;
Pruunsild, Priit;
Timmusk, Tõnis

Publication type:

Article

Efficient use of a translation start codon in BDNF exon I.

Published in:

Journal of Neurochemistry, 2015, v. 134, n. 6, p. 1015, doi. 10.1111/jnc.13124

By:

Koppel, Indrek;
Tuvikene, Jürgen;
Lekk, Ingrid;
Timmusk, Tõnis

Publication type:

Article

Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system.

Published in:

BMC Developmental Biology, 2009, v. 9, p. 1, doi. 10.1186/1471-213X-9-10

By:

Piirsoo, Marko;
Meijer, Dies;
Timmusk, Tõnis

Publication type:

Article

Novel transcripts reveal a complex structure of the human TRKA gene and imply the presence of multiple protein isoforms.

Published in:

2015

By:

Luberg, Kristi;
Park, Rahel;
Aleksejeva, Elina;
Timmusk, Tőnis;
Timmusk, Tõnis

Publication type:

journal article

BAC-based cellular model for screening regulators of BDNF gene transcription.

Published in:

BMC Neuroscience, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2202-15-75

By:

Jaanson, Kaur;
Sepp, Mari;
Tamara Aid-Pavlidis;
Timmusk, Tõnis

Publication type:

Article

BAC-based cellular model for screening regulators of BDNF gene transcription.

Published in:

2014

By:

Jaanson, Kaur;
Sepp, Mari;
Aid-Pavlidis, Tamara;
Timmusk, Tonis;
Timmusk, Tõnis

Publication type:

journal article

An 840 kb distant upstream enhancer is a crucial regulator of catecholamine‐dependent expression of the Bdnf gene in astrocytes.

Published in:

Glia (0894-1491), 2024, v. 72, n. 1, p. 90, doi. 10.1002/glia.24463

By:

Avarlaid, Annela;
Esvald, Eli‐Eelika;
Koppel, Indrek;
Parkman, Annabel;
Zhuravskaya, Anna;
Makeyev, Eugene V.;
Tuvikene, Jürgen;
Timmusk, Tõnis

Publication type:

Article

Cover Image, Volume 72, Issue 1.

Published in:

Glia (0894-1491), 2024, v. 72, n. 1, p. C1, doi. 10.1002/glia.24393

By:

Avarlaid, Annela;
Esvald, Eli‐Eelika;
Koppel, Indrek;
Parkman, Annabel;
Zhuravskaya, Anna;
Makeyev, Eugene V.;
Tuvikene, Jürgen;
Timmusk, Tõnis

Publication type:

Article

Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression.

Published in:

Journal of Neurochemistry, 2012, v. 123, n. 1, p. 29, doi. 10.1111/j.1471-4159.2012.07796.x

By:

Pruunsild, Priit;
Timmusk, Tõnis

Publication type:

Article

Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development.

Published in:

Journal of Neurochemistry, 2010, v. 113, n. 4, p. 952, doi. 10.1111/j.1471-4159.2010.06662.x

By:

Luberg, Kristi;
Wong, Jenny;
Weickert, Cynthia Shannon;
Timmusk, Tõnis

Publication type:

Article

N-terminally truncated BAF57 isoforms contribute to the diversity of SWI/SNF complexes in neurons.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 3, p. 807, doi. 10.1111/j.1471-4159.2009.06005.x

By:

Kazantseva, Anna;
Sepp, Mari;
Kazantseva, Jekaterina;
Sadam, Helle;
Pruunsild, Priit;
Timmusk, Tõnis;
Neuman, Toomas;
Palm, Kaia

Publication type:

Article

Neuronal K<sup>+</sup>/Cl<sup>–</sup> co-transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone-specific expression and developmental up-regulation of endogenous KCC2 gene.

Published in:

Journal of Neurochemistry, 2005, v. 95, n. 4, p. 1144, doi. 10.1111/j.1471-4159.2005.03434.x

By:

Uvarov, Pavel;
Pruunsild, Priit;
Timmusk, Tõnis;
Airaksinen, Matti S.

Publication type:

Article

Glucocorticoid Receptor Stimulation Resulting from Early Life Stress Affects Expression of DNA Methyltransferases in Rat Prefrontal Cortex.

Published in:

Journal of Molecular Neuroscience, 2019, v. 68, n. 1, p. 99, doi. 10.1007/s12031-019-01286-z

By:

Urb, Mari;
Anier, Kaili;
Matsalu, Terje;
Aonurm-Helm, Anu;
Tasa, Gunnar;
Koppel, Indrek;
Zharkovsky, Alexander;
Timmusk, Tõnis;
Kalda, Anti

Publication type:

Article

Seizures increase trkC mRNA expression in the dentate gyrus of rat hippocampus.

Published in:

Journal of Molecular Neuroscience, 1995, v. 6, n. 1, p. 11, doi. 10.1007/BF02736755

By:

Mudò, Giuseppa;
Salin, Tuija;
Condorelli, Daniele;
Jiang, Xing;
Dell'Albani, Paola;
Timmusk, Tõnis;
Metsis, Madis;
Funakoshi, Hiroshi;
Belluardo, Natale

Publication type:

Article

The Fuchs corneal dystrophy-associated CTG repeat expansion in the TCF4 gene affects transcription from its alternative promoters.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75437-3

By:

Sirp, Alex;
Leite, Kristian;
Tuvikene, Jürgen;
Nurm, Kaja;
Sepp, Mari;
Timmusk, Tõnis

Publication type:

Article

The role of DNA methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice.

Published in:

2020

By:

Urb, Mari;
Niinep, Kerly;
Matsalu, Terje;
Kipper, Karin;
Herodes, Koit;
Zharkovsky, Alexander;
Timmusk, Tõnis;
Anier, Kaili;
Kalda, Anti

Publication type:

journal article

Isoform-Specific Reduction of the Basic Helix-Loop-Helix Transcription Factor TCF4 Levels in Huntington’s Disease.

Published in:

eNeuro, 2021, v. 8, n. 5, p. 1, doi. 10.1523/ENEURO.0197-21.2021

By:

Nurm, Kaja;
Sepp, Mari;
Castany-Pladevall, Carla;
Creus-Muncunill, Jordi;
Tuvikene, Jürgen;
Sirp, Alex;
Vihma, Hanna;
Blake, Derek J.;
Perez-Navarro, Esther;
Timmusk, Tõnis

Publication type:

Article

Pitt–Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 13, p. 2873, doi. 10.1093/hmg/dds112

By:

Sepp, Mari;
Pruunsild, Priit;
Timmusk, Tõnis

Publication type:

Article

NF-κB-dependent regulation of brain-derived neurotrophic factor in hippocampal neurons by X-linked inhibitor of apoptosis protein.

Published in:

European Journal of Neuroscience, 2009, v. 30, n. 6, p. 958, doi. 10.1111/j.1460-9568.2009.06898.x

By:

Kairisalo, Minna;
Korhonen, Laura;
Sepp, Mari;
Pruunsild, Priit;
Kukkonen, Jyrki P.;
Kivinen, Jenny;
Timmusk, Tõnis;
Blomgren, Klas;
Lindholm, Dan

Publication type:

Article

Meta-coexpression conservation analysis of microarray data: a "subset" approach provides insight into brain-derived neurotrophic factor regulation.

Published in:

BMC Genomics, 2009, v. 10, p. 420, doi. 10.1186/1471-2164-10-420

By:

Aid-Pavlidis, Tamara;
Pavlidis, Pavlos;
Timmusk, Tõnis

Publication type:

Article