Works by Tima, Singkome

Results: 37

FLT3-specific curcumin micelles enhance activity of curcumin on FLT3-ITD overexpressing MV4-11 leukemic cells.

Published in:

Drug Development & Industrial Pharmacy, 2019, v. 45, n. 3, p. 498, doi. 10.1080/03639045.2018.1562462

By:

Tima, Singkome;
Okonogi, Siriporn;
Ampasavate, Chadarat;
Berkland, Cory;
Anuchapreeda, Songyot

Publication type:

Article

Effect of pre-low-dose irradiation on anticancer activities of gallic acid in leukemic K562 and K562/Dox cells: cell viability and cellular energetic state studies.

Published in:

2022

By:

Aye, Khin TheNu;
Wattanapongpitak, Sakornniya;
Supawat, Benjamaporn;
Kothan, Suchart;
Udomtanakunchai, Chatchanok;
Tima, Singkome;
Tungjai, Montree

Publication type:

journal article

Anticancer activity of Zingiber ottensii essential oil and its nanoformulations.

Published in:

PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0262335

By:

Panyajai, Pawaret;
Chueahongthong, Fah;
Viriyaadhammaa, Natsima;
Nirachonkul, Wariya;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Anuchapreeda, Songyot;
Okonogi, Siriporn

Publication type:

Article

Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells.

Published in:

Archives of Pharmacal Research, 2006, v. 29, n. 10, p. 866, doi. 10.1007/BF02973907

By:

Anuchapreeda, Songyot;
Thanarattanakorn, Pattra;
Sittipreechacharn, Somjai;
Tima, Singkome;
Chanarat, Prasit;
Limtrakul, Pornngarm

Publication type:

Article

Gallic acid enhances pirarubicin-induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P-glycoprotein inhibition.

Published in:

Oncology Reports, 2021, v. 46, n. 4, p. N.PAG, doi. 10.3892/or.2021.8178

By:

Aye, Khin Thenu;
Wattanapongpitak, Sakornniya;
Supawat, Benjamaporn;
Kothan, Suchart;
Udomtanakunchai, Chatchanok;
Tima, Singkome;
Pan, Jie;
Tungjai, Montree

Publication type:

Article

Costunolide and parthenolide from Champi Sirindhorn (Magnolia sirindhorniae) inhibit leukemic cell proliferation in K562 and molt-4 cell lines.

Published in:

Natural Product Research, 2021, v. 35, n. 6, p. 988, doi. 10.1080/14786419.2019.1610752

By:

Saosathan, Sawalee;
Khounvong, Jalernsri;
Rungrojsakul, Methee;
Katekunlaphan, Trinnakorn;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Berkland, Cory;
Anuchapreeda, Songyot

Publication type:

Article

Exploring breast cancer associated-gene panel for next-generation sequencing and identifying new, pathogenic variants in breast cancer from western China.

Published in:

Journal of Cancer, 2025, v. 16, n. 4, p. 1281, doi. 10.7150/jca.101911

By:

Jingliang Cheng;
Binghui Song;
Chunli Wei;
Lianmei Zhang;
Xiaoyan Liu;
Lisha Yang;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Xiuli Xiao;
Anuchapreeda, Songyot;
Junjiang Fu

Publication type:

Article

RETRACTED: Fahmy et al. Intranasal Niosomal In Situ Gel as a Promising Approach for Enhancing Flibanserin Bioavailability and Brain Delivery: In Vitro Optimization and Ex Vivo/In Vivo Evaluation. Pharmaceutics 2020, 12 , 485.

Published in:

2024

By:

Fahmy, Usama A.;
Badr-Eldin, Shaimaa M.;
Ahmed, Osama A. A.;
Aldawsari, Hibah M.;
Tima, Singkome;
Asfour, Hani Z.;
Al-Rabia, Mohammed W.;
Negm, Aya A.;
Sultan, Muhammad H.;
Madkhali, Osama A. A.;
Alhakamy, Nabil A.

Publication type:

Correction Notice

Curcumin-Loaded Platelet Membrane Bioinspired Chitosan-Modified Liposome for Effective Cancer Therapy.

Published in:

Pharmaceutics, 2023, v. 15, n. 2, p. 631, doi. 10.3390/pharmaceutics15020631

By:

Wan, Shengli;
Fan, Qingze;
Wu, Yuesong;
Zhang, Jingqing;
Qiao, Gan;
Jiang, Nan;
Yang, Jie;
Liu, Yuanzhi;
Li, Jingyan;
Chiampanichayakul, Sawitree;
Tima, Singkome;
Tong, Fei;
Anuchapreeda, Songyot;
Wu, Jianming

Publication type:

Article

Bioinspired Platelet-like Nanovector for Enhancing Cancer Therapy via P-Selectin Targeting.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2614, doi. 10.3390/pharmaceutics14122614

By:

Wan, Shengli;
Wu, Yuesong;
Fan, Qingze;
Yang, Gang;
Hu, Haiyang;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Anuchapreeda, Songyot;
Wu, Jianming

Publication type:

Article

Doxorubicin-Loaded Polymeric Micelles Conjugated with CKR- and EVQ-FLT3 Peptides for Cytotoxicity in Leukemic Stem Cells.

Published in:

Pharmaceutics, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/pharmaceutics14102115

By:

Chueahongthong, Fah;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Dejkriengkraikul, Pornngarm;
Okonogi, Siriporn;
Sasarom, Mathurada;
Rodwattanagul, Soraya;
Berkland, Cory;
Anuchapreeda, Songyot

Publication type:

Article

Merging Experimental Design and Nanotechnology for the Development of Optimized Simvastatin Spanlastics: A Promising Combined Strategy for Augmenting the Suppression of Various Human Cancer Cells.

Published in:

Pharmaceutics, 2022, v. 14, n. 5, p. 1024, doi. 10.3390/pharmaceutics14051024

By:

Badr-Eldin, Shaimaa M.;
Aldawsari, Hibah M.;
Alhakamy, Nabil A.;
Fahmy, Usama A.;
Ahmed, Osama A. A.;
Neamatallah, Thikryat;
Tima, Singkome;
Almaghrabi, Raghad H.;
Alkudsi, Fayda M.;
Alamoudi, Asmaa A.;
Alzahrani, Amjad A.;
Kotta, Sabna;
Al-hejaili, Omar D.

Publication type:

Article

Phyto-Phospholipid Conjugated Scorpion Venom Nanovesicles as Promising Carrier That Improves Efficacy of Thymoquinone against Adenocarcinoma Human Alveolar Basal Epithelial Cells.

Published in:

Pharmaceutics, 2021, v. 13, n. 12, p. 2144, doi. 10.3390/pharmaceutics13122144

By:

Asfour, Hani Z.;
Fahmy, Usama A.;
Alharbi, Waleed S.;
Almehmady, Alshaimaa M.;
Alamoudi, Abdulmohsin J.;
Tima, Singkome;
Mansouri, Rasha A.;
Omar, Ulfat M.;
Ahmed, Osama A. A.;
Zakai, Shadi A.;
Aldarmahi, Ahmed A.;
Bagalagel, Alaa;
Diri, Reem;
Alhakamy, Nabil A.

Publication type:

Article

Development of Microemulsion Containing Alpinia galanga Oil and Its Major Compounds: Enhancement of Antimicrobial Activities.

Published in:

Pharmaceutics, 2021, v. 13, n. 2, p. 265, doi. 10.3390/pharmaceutics13020265

By:

Khumpirapang, Nattakanwadee;
Klayraung, Srikanjana;
Tima, Singkome;
Okonogi, Siriporn

Publication type:

Article

Intranasal Niosomal In Situ Gel as a Promising Approach for Enhancing Flibanserin Bioavailability and Brain Delivery: In Vitro Optimization and Ex Vivo/In Vivo Evaluation.

Published in:

Pharmaceutics, 2020, v. 12, n. 6, p. 485, doi. 10.3390/pharmaceutics12060485

By:

Fahmy, Usama A.;
Badr-Eldin, Shaimaa M.;
Ahmed, Osama A. A.;
Aldawsari, Hibah M.;
Tima, Singkome;
Asfour, Hani Z.;
Al-Rabia, Mohammed W.;
Negm, Aya A.;
Sultan, Muhammad H.;
Madkhali, Osama A. A.;
Alhakamy, Nabil A.

Publication type:

Article

Dietary Turmeric Bisdemethoxycurcumin Suppresses Wilms' Tumor 1 and CD34 Protein Expressions in KG-1a Leukemic Stem Cells.

Published in:

Nutrition & Cancer, 2019, v. 71, n. 7, p. 1189, doi. 10.1080/01635581.2019.1598565

By:

Panyajai, Pawaret;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Anuchapreeda, Songyot

Publication type:

Article

FLT3, a prognostic biomarker for acute myeloid leukemia (AML): Quantitative monitoring with a simple anti-FLT3 interaction and flow cytometric method.

Published in:

2019

By:

Ampasavate, Chadarat;
Jutapakdee, Wasimon;
Phongpradist, Rungsinee;
Tima, Singkome;
Tantiworawit, Adisak;
Charoenkwan, Pimlak;
Chinwong, Dujrudee;
Anuchapreeda, Songyot

Publication type:

journal article

Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 4, p. 585, doi. 10.1007/s00280-007-0642-1

By:

Anuchapreeda, Songyot;
Tima, Singkome;
Duangrat, Chadarat;
Limtrakul, Pornngarm

Publication type:

Article

Anticancer activity of Curcuma aeroginosa essential oil and its nano-formulations: cytotoxicity, apoptosis and cell migration effects.

Published in:

BMC Complementary Medicine & Therapies, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12906-023-04261-9

By:

Panyajai, Pawaret;
Viriyaadhammaa, Natsima;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Dejkriengkraikul, Pornngarm;
Okonogi, Siriporn;
Anuchapreeda, Songyot

Publication type:

Article

Biological activities of extracts and compounds from Thai Kae-Lae (Maclura cochinchinensis (Lour.) Corner).

Published in:

BMC Complementary Medicine & Therapies, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12906-023-03979-w

By:

Rueankham, Lapamas;
Panyajai, Pawaret;
Saiai, Aroonchai;
Rungrojsakul, Methee;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Yeerong, Kankanit;
Somwongin, Suvimol;
Chaiyana, Wantida;
Dejkriengkraikul, Pornngarm;
Okonogi, Siriporn;
Katekunlaphan, Trinnakorn;
Anuchapreeda, Songyot

Publication type:

Article

Waist Circumference and BMI Are Strongly Correlated with MRI-Derived Fat Compartments in Young Adults.

Published in:

Life (2075-1729), 2021, v. 11, n. 7, p. 643, doi. 10.3390/life11070643

By:

Pasanta, Duanghathai;
Htun, Khin Thandar;
Pan, Jie;
Tungjai, Montree;
Kaewjaeng, Siriprapa;
Chancharunee, Sirirat;
Tima, Singkome;
Kim, Hong Joo;
Kæwkhao, Jakrapong;
Kothan, Suchart

Publication type:

Article

Optimized Apamin-Mediated Nano-Lipidic Carrier Potentially Enhances the Cytotoxicity of Ellagic Acid against Human Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9440, doi. 10.3390/ijms23169440

By:

Badr-Eldin, Shaimaa M.;
Aldawsari, Hibah M.;
Fahmy, Usama A.;
Ahmed, Osama A. A.;
Alhakamy, Nabil A.;
Al-hejaili, Omar D.;
Alhassan, Alhanoof A.;
Ammari, Ghadeer A.;
Alhazmi, Shouq I.;
Alawadi, Raghad M.;
Bakhaidar, Rana;
Alamoudi, Abdulmohsen J.;
Neamatallah, Thikryat;
Tima, Singkome

Publication type:

Article

A Novel Drug Modulator Diarylheptanoid (t rans -1,7-Diphenyl-5-hydroxy-1-heptene) from Curcuma comosa Rhizomes for P-glycoprotein Function and Apoptosis Induction in K652/ADR Leukemic Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 8989, doi. 10.3390/ijms23168989

By:

Viriyaadhammaa, Natsima;
Duangmano, Suwit;
Saiai, Aroonchai;
Tungjai, Montree;
Dejkriengkraikul, Pornngarm;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Krise, Jeffrey;
Anuchapreeda, Songyot

Publication type:

Article

Anti-leukemia activity of the ethyl acetate extract from Gynostemma pentaphyllum (Thunb.) leaf against FLT3-overexpressing AML cells and its phytochemical characterization.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04903-0

By:

Gyi, Khin Khin;
Anuchapreeda, Songyot;
Intasai, Nutjeera;
Tungjai, Montree;
Okonogi, Siriporn;
Iwasaki, Arihiro;
Usuki, Toyonobu;
Tima, Singkome

Publication type:

Article

Icaritin‐Loaded Liposomes Mediated by Hyaluronic Acid Promoted the Anti‐Proliferation and Senescence in Huh7 Cells.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70104

By:

Lu, Ruilin;
Long, Xin;
Li, Xiyao;
Li, Jiaxin;
Liu, Zhen;
Chai, Kexin;
Zhang, Yujie;
Lin, Yan;
Liu, Zhongbing;
Tima, Singkome;
Zhong, Zhirong;
Sun, Xiaoduan

Publication type:

Article

Sema4D silencing increases the sensitivity of nivolumab to B16-F10 resistant melanoma via inhibiting the PI3K/AKT signaling pathway.

Published in:

PeerJ, 2023, p. 1, doi. 10.7717/peerj.15172

By:

Zhuo Zhang;
Duoli Zhang;
Fang Wang;
Jiao Liu;
Yuhong Sun;
Songyot Anuchapreeda;
Singkome Tima;
Zhangang Xiao;
Suwit Duangmano

Publication type:

Article

Different responses of normal cells (red blood cells) and cancer cells (K562 and K562/Dox cells) to low-dose 137Cs gamma-rays.

Published in:

Molecular & Clinical Oncology, 2021, v. 14, n. 4, p. N.PAG, doi. 10.3892/mco.2021.2236

By:

Supawat, Benjamaporn;
Homnuan, Panumas;
Kanthawong, Natthawan;
Semrasa, Niyada;
Tima, Singkome;
Kothan, Suchart;
Udomtanakunchai, Chatchanok;
Tungjai, Montree

Publication type:

Article

Nutricosmetic effects of Asparagus officinalis: a potent matrix metalloproteinase-1 inhibitor.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88340-2

By:

Sriyab, Suwannee;
Laosirisathian, Nachtharinee;
Punyoyai, Chanun;
Anuchapreeda, Songyot;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Chaiyana, Wantida

Publication type:

Article

Hyaluronic acid-modified liposomes Potentiated in-vivo anti-hepatocellular carcinoma of icaritin.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1437515

By:

Xiaoduan Sun;
Zhenzhen He;
Ruilin Lu;
Zhongbing Liu;
Chiampanichayakul, Sawitree;
Anuchapreeda, Songyot;
Jun Jiang;
Tima, Singkome;
Zhirong Zhong

Publication type:

Article

Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications.

Published in:

Polymers (20734360), 2022, v. 14, n. 19, p. 4202, doi. 10.3390/polym14194202

By:

Vaithanomsat, Pilanee;
Boonlum, Nutthamon;
Chaiyana, Wantida;
Tima, Singkome;
Anuchapreeda, Songyot;
Trakunjae, Chanaporn;
Apiwatanapiwat, Waraporn;
Janchai, Phornphimon;
Boondaeng, Antika;
Nimitkeatkai, Hataitip;
Jarerat, Amnat

Publication type:

Article

PD-L1 regulates cell proliferation and apoptosis in acute myeloid leukemia by activating PI3K-AKT signaling pathway.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15020-0

By:

Wang, Fang;
Yang, Liqiong;
Xiao, Mintao;
Zhang, Zhuo;
Shen, Jing;
Anuchapreeda, Songyot;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Xiao, Zhangang

Publication type:

Article

CD123-Targeted Nano-Curcumin Molecule Enhances Cytotoxic Efficacy in Leukemic Stem Cells.

Published in:

Nanomaterials (2079-4991), 2021, v. 11, n. 11, p. 2974, doi. 10.3390/nano11112974

By:

Nirachonkul, Wariya;
Ogonoki, Siriporn;
Thumvijit, Tarika;
Chiampanichayakul, Supanimit;
Panyajai, Pawaret;
Anuchapreeda, Songyot;
Tima, Singkome;
Chiampanichayakul, Sawitree

Publication type:

Article

Hydrolyzed Flavonoids from Cyrtosperma johnstonii with Superior Antioxidant, Antiproliferative, and Anti-Inflammatory Potential for Cancer Prevention.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3226, doi. 10.3390/molecules27103226

By:

Naksuriya, Ornchuma;
Daowtak, Krai;
Tima, Singkome;
Okonogi, Siriporn;
Mueller, Monika;
Toegel, Stefan;
Khonkarn, Ruttiros

Publication type:

Article

Co-Treatments of Edible Curcumin from Turmeric Rhizomes and Chemotherapeutic Drugs on Cytotoxicity and FLT3 Protein Expression in Leukemic Stem Cells.

Published in:

Molecules, 2021, v. 26, n. 19, p. 5785, doi. 10.3390/molecules26195785

By:

Chueahongthong, Fah;
Tima, Singkome;
Chiampanichayakul, Sawitree;
Berkland, Cory;
Anuchapreeda, Songyot

Publication type:

Article

Cytotoxic and Antiproliferative Effects of Diarylheptanoids Isolated from Curcuma comosa Rhizomes on Leukaemic Cells.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5476, doi. 10.3390/molecules25225476

By:

Viriyaadhammaa, Natsima;
Saiai, Aroonchai;
Neimkhum, Waranya;
Nirachonkul, Wariya;
Chaiyana, Wantida;
Chiampanichayakul, Sawitree;
Tima, Singkome;
Usuki, Toyonobu;
Duangmano, Suwit;
Anuchapreeda, Songyot;
Tesoriere, Luisa;
Attanzio, Alessandro

Publication type:

Article

Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime (Citrus hystrix) Leaves.

Published in:

Molecules, 2020, v. 25, n. 6, p. 1300, doi. 10.3390/molecules25061300

By:

Anuchapreeda, Songyot;
Chueahongthong, Fah;
Viriyaadhammaa, Natsima;
Panyajai, Pawaret;
Anzawa, Riki;
Tima, Singkome;
Ampasavate, Chadarat;
Saiai, Aroonchai;
Rungrojsakul, Methee;
Usuki, Toyonobu;
Okonogi, Siriporn;
Keyzers, Rob

Publication type:

Article

Enhanced Cosmeceutical Potentials of the Oil from Gryllus bimaculatus de Geer by Nanoemulsions.

Published in:

International Journal of Nanomedicine, 2023, v. 18, p. 2955, doi. 10.2147/IJN.S406864

By:

Chaiyana, Wantida;
Jiamphun, Sudarat;
Bezuidenhout, Suchanan;
Yeerong, Kankanit;
Krueathanasing, Nutnicha;
Thammasorn, Pattiya;
Jittasai, Pipat;
Tanakitvanicharoen, Suphachai;
Tima, Singkome;
Anuchapreeda, Songyot

Publication type:

Article