Works by Tilley, Wayne D.

Results: 48

Elevated levels of tumour apolipoprotein D independently predict poor outcome in breast cancer patients.

Published in:

Histopathology, 2020, v. 76, n. 7, p. 976, doi. 10.1111/his.14081

By:

Jankovic‐Karasoulos, Tanja;
Bianco‐Miotto, Tina;
Butler, Miriam S;
Butler, Lisa M;
McNeil, Catriona M;
O'Toole, Sandra A;
Millar, Ewan K A;
Sakko, Andrew J;
Ruiz, Alexandra I;
Birrell, Stephen N;
Sutherland, Robert L;
Hickey, Theresa E;
Tilley, Wayne D;
Ricciardelli, Carmela

Publication type:

Article

Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 23, p. 6741, doi. 10.1093/nar/gkg909

By:

Kim, Joshua;
Jia, Li;
Tilley, Wayne D.;
Coetzee, Gerhard A.

Publication type:

Article

A Deep Learning Approach for the Classification of Fibroglandular Breast Density in Histology Images of Human Breast Tissue.

Published in:

Cancers, 2025, v. 17, n. 3, p. 449, doi. 10.3390/cancers17030449

By:

Heydarlou, Hanieh;
Hodson, Leigh J.;
Dorraki, Mohsen;
Hickey, Theresa E.;
Tilley, Wayne D.;
Smith, Eric;
Ingman, Wendy V.;
Farajpour, Ali

Publication type:

Article

Androgen Receptor Signaling in Prostate Cancer Genomic Subtypes.

Published in:

Cancers, 2021, v. 13, n. 13, p. 3272, doi. 10.3390/cancers13133272

By:

Jillson, Lauren K.;
Yette, Gabriel A.;
Laajala, Teemu D.;
Tilley, Wayne D.;
Costello, James C.;
Cramer, Scott D.

Publication type:

Article

A patient‐derived explant (PDE) model of hormone‐dependent cancer.

Published in:

Molecular Oncology, 2018, v. 12, n. 9, p. 1608, doi. 10.1002/1878-0261.12354

By:

Centenera, Margaret M.;
Hickey, Theresa E.;
Jindal, Shalini;
Ryan, Natalie K.;
Ravindranathan, Preethi;
Mohammed, Hisham;
Robinson, Jessica L.;
Schiewer, Matthew J.;
Ma, Shihong;
Kapur, Payal;
Sutherland, Peter D.;
Hoffmann, Clive E.;
Roehrborn, Claus G.;
Gomella, Leonard G.;
Carroll, Jason S.;
Birrell, Stephen N.;
Knudsen, Karen E.;
Raj, Ganesh V.;
Butler, Lisa M.;
Tilley, Wayne D.

Publication type:

Article

Breast cancer prognosis predicted by nuclear receptor-coregulator networks.

Published in:

Molecular Oncology, 2014, v. 8, n. 5, p. 998, doi. 10.1016/j.molonc.2014.03.017

By:

Doan, Tram B.;
Eriksson, Natalie A.;
Graham, Dinny;
Funder, John W.;
Simpson, Evan R.;
Kuczek, Elizabeth S.;
Clyne, Colin;
Leedman, Peter J.;
Tilley, Wayne D.;
Fuller, Peter J.;
Muscat, George E.O.;
Clarke, Christine L.

Publication type:

Article

Author Correction: CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.

Published in:

2024

By:

Rahman, Razia;
Rahaman, Muhammed H.;
Hanson, Adrienne R.;
Choo, Nicholas;
Xie, Jianling;
Townley, Scott L.;
Shrestha, Raj;
Hassankhani, Ramin;
Islam, Saiful;
Ramm, Susanne;
Simpson, Kaylene J.;
Risbridger, Gail P.;
Best, Giles;
Centenera, Margaret M.;
Balk, Steven P.;
Kichenadasse, Ganessan;
Taylor, Renea A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Conn, Simon J.

Publication type:

Correction Notice

CDK9 inhibition inhibits multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.

Published in:

British Journal of Cancer, 2024, v. 131, n. 6, p. 1092, doi. 10.1038/s41416-024-02810-8

By:

Rahman, Razia;
Rahaman, Muhammed H.;
Hanson, Adrienne R.;
Choo, Nicholas;
Xie, Jianling;
Townley, Scott L.;
Shrestha, Raj;
Hassankhani, Ramin;
Islam, Saiful;
Ramm, Susanne;
Simpson, Kaylene J.;
Risbridger, Gail P.;
Best, Giles;
Centenera, Margaret M.;
Balk, Steven P.;
Kichenadasse, Ganessan;
Taylor, Renea A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Conn, Simon J.

Publication type:

Article

Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.

Published in:

2021

By:

Hickey, Theresa E.;
Dwyer, Amy R.;
Tilley, Wayne D.

Publication type:

journal article

Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b.

Published in:

2018

By:

Snell, Cameron E.;
Gough, Madeline;
Liu, Cheng;
Middleton, Kathryn;
Pyke, Christopher;
Shannon, Catherine;
Woodward, Natasha;
Hickey, Theresa E.;
Armes, Jane E.;
Tilley, Wayne D.

Publication type:

journal article

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.

Published in:

EMBO Journal, 2012, v. 31, n. 6, p. 1617, doi. 10.1038/emboj.2012.59

By:

Robinson, Jessica L L;
MacArthur, Stewart;
Ross-Innes, Caryn S;
Tilley, Wayne D;
Neal, David E;
Mills, Ian G;
Carroll, Jason S

Publication type:

Article

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.

Published in:

EMBO Journal, 2011, v. 30, n. 15, p. 3019, doi. 10.1038/emboj.2011.216

By:

Robinson, Jessica L L;
MacArthur, Stewart;
Ross-Innes, Caryn S;
Tilley, Wayne D;
Neal, David E;
Mills, Ian G;
Carroll, Jason S

Publication type:

Article

Effect of pubertal development on estrogen receptor levels and stromal morphology in the guinea pig prostate.

Published in:

Prostate, 1989, v. 15, n. 2, p. 195, doi. 10.1002/pros.2990150213

By:

Tilley, Wayne D.;
Horsfall, David J.;
Skinner, John M.;
Henderson, Douglas W.;
Marshall, Villis R.

Publication type:

Article

Renewed interest in the progesterone receptor in breast cancer.

Published in:

2016

By:

Lim, Elgene;
Palmieri, Carlo;
Tilley, Wayne D

Publication type:

Editorial

miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking.

Published in:

EMBO Journal, 2018, v. 37, n. 13, p. 1, doi. 10.15252/embj.201899016

By:

Pillman, Katherine A.;
Phillips, Caroline A.;
Roslan, Suraya;
Toubia, John;
Dredge, B. Kate;
Bert, Andrew G.;
Lumb, Rachael;
Neumann, Daniel P.;
Li, Xiaochun;
Conn, Simon J.;
Liu, Dawei;
Bracken, Cameron P.;
Lawrence, David M.;
Stylianou, Nataly;
Schreiber, Andreas W.;
Tilley, Wayne D.;
Hollier, Brett G.;
Khew‐Goodall, Yeesim;
Selth, Luke A.;
Goodall, Gregory J.

Publication type:

Article

Disruption of androgen receptor signaling by synthetic progestins may increase risk of developing breast cancer.

Published in:

FASEB Journal, 2007, v. 21, n. 10, p. 2285, doi. 10.1096/fj.06-7518com

By:

Birrell, Stephen N.;
Butler, Lisa M.;
Harris, Jonathan M.;
Buchanan, Grant;
Tilley, Wayne D.

Publication type:

Article

Identification of novel androgen receptor target genes in prostate cancer.

Published in:

Molecular Cancer, 2007, v. 6, p. 39, doi. 10.1186/1476-4598-6-39

By:

Jariwala, Unnati;
Prescott, Jennifer;
Li Jia;
Barski, Artem;
Pregizer, Steve;
Cogan, Jon P.;
Arasheben, Armin;
Tilley, Wayne D.;
Scher, Howard I.;
Gerald, William L.;
Buchanan, Grant;
Coetzee, Gerhard A.;
Frenkel, Baruch

Publication type:

Article

5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia.

Published in:

International Journal of Cancer, 2007, v. 120, n. 4, p. 776, doi. 10.1002/ijc.22408

By:

Hayes, Vanessa M.;
Severi, Gianluca;
Padilla, Emma J.D.;
Morris, Howard A.;
Tilley, Wayne D.;
Southey, Melissa C.;
English, Dallas R.;
Sutherland, Robert L.;
Hopper, John L.;
Boyle, Peter;
Giles, Graham G.

Publication type:

Article

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL.

Published in:

International Journal of Cancer, 2006, v. 119, n. 4, p. 944, doi. 10.1002/ijc.21939

By:

Butler, Lisa M.;
Liapis, Vasilios;
Bouralexis, Stelios;
Welldon, Katie;
Hay, Shelley;
Thai, Le M.;
Labrinidis, Agatha;
Tilley, Wayne D.;
Findlay, David M.;
Evdokiou, Andreas

Publication type:

Article

Library size confounds biology in spatial transcriptomics data.

Published in:

Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03241-7

By:

Bhuva, Dharmesh D.;
Tan, Chin Wee;
Salim, Agus;
Marceaux, Claire;
Pickering, Marie A.;
Chen, Jinjin;
Kharbanda, Malvika;
Jin, Xinyi;
Liu, Ning;
Feher, Kristen;
Putri, Givanna;
Tilley, Wayne D.;
Hickey, Theresa E.;
Asselin-Labat, Marie-Liesse;
Phipson, Belinda;
Davis, Melissa J.

Publication type:

Article

The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.

Published in:

Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-023-03161-y

By:

Hosseinzadeh, Leila;
Kikhtyak, Zoya;
Laven-Law, Geraldine;
Pederson, Stephen M.;
Puiu, Caroline G.;
D'Santos, Clive S.;
Lim, Elgene;
Carroll, Jason S.;
Tilley, Wayne D.;
Dwyer, Amy R.;
Hickey, Theresa E.

Publication type:

Article

Expression of Drosophila Ca<sup>2+</sup> permeable transient receptor potential-like channel protein in a prostate cancer cell line decreases cell survival.

Published in:

Cancer Gene Therapy, 2003, v. 10, n. 8, p. 611, doi. 10.1038/sj.cgt.7700608

By:

Zhang, Lei;
Brereton, Helen M;
Hahn, Michael;
Froscio, Mario;
Tilley, Wayne D;
Brown, Michael P;
Barritt, Greg J

Publication type:

Article

Breast and prostate cancer: more similar than different.

Published in:

2010

By:

Risbridger, Gail P.;
Davis, Ian D.;
Birrell, Stephen N.;
Tilley, Wayne D.

Publication type:

journal article

Partial Androgen Insensitivity Caused by an Androgen Receptor Mutation at Amino Acid 907 (Gly→Arg) That Results in Decreased Ligand Binding Affinity and Reduced Androgen Receptor Messenger Ribonucleic Acid Levels.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 1, p. 236, doi. 10.1210/jc.81.1.236

By:

CHOONG, CATHERINE S.;
STURM, MARIAN J.;
STROPHAIR, JULIE A.;
McCULLOCH, ROSS K.;
TILLEY, WAYNE D.;
LEEDMAN, PETER J.;
HURLEY, DAVID M.

Publication type:

Article

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor.

Published in:

Biological Chemistry, 2005, v. 386, n. 1, p. 69, doi. 10.1515/BC.2005.009

By:

Shen, Howard C.;
Buchanan, Grant;
Butler, Lisa M.;
Prescott, Jennifer;
Henderson, Michael;
Tilley, Wayne D.;
Coetzee, Gerhard A.

Publication type:

Article

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

Published in:

Prostate, 2013, v. 73, n. 2, p. 182, doi. 10.1002/pros.22554

By:

Chiam, Karen;
Ryan, Natalie K.;
Ricciardelli, Carmela;
Day, Tanya K.;
Buchanan, Grant;
Ochnik, Aleksandra M.;
Murti, Krisna;
Selth, Luke A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Bianco‐Miotto, Tina

Publication type:

Article

Serum testosterone bioassay evaluation in a large male cohort.

Published in:

Clinical Endocrinology, 2010, v. 72, n. 1, p. 87, doi. 10.1111/j.1365-2265.2009.03595.x

By:

Need, Eleanor F.;
O'Loughlin, Peter D.;
Armstrong, David T.;
Haren, Matthew T.;
Martin, Sean A.;
Tilley, Wayne D.;
Wittert, Gary A.;
Buchanan, Grant

Publication type:

Article

Regulation of androgen receptor gene expression by steroids and retinoic acid in human breast-cancer cells.

Published in:

International Journal of Cancer, 1992, v. 52, n. 5, p. 778, doi. 10.1002/ijc.2910520518

By:

Hall, Rosemary E.;
Tilley, Wayne D.;
McPhaul, Michael J.;
Sutherland, Robert L.

Publication type:

Article

Expression and localisation of c-kit and KITL in the adult human ovary.

Published in:

Journal of Ovarian Research, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13048-015-0159-x

By:

Tuck, Astrud R.;
Robker, Rebecca L.;
Norman, Robert J.;
Tilley, Wayne D.;
Hickey, Theresa E.

Publication type:

Article

Prostatic chondroitin sulfate is increased in patients with metastatic disease but does not predict survival outcome.

Published in:

Prostate, 2009, v. 69, n. 7, p. 761, doi. 10.1002/pros.20926

By:

Ricciardelli, Carmela;
Sakko, Andrew J.;
Stahl, Jürgen;
Tilley, Wayne D.;
Marshall, Villis R.;
Horsfall, David J.

Publication type:

Article

Elevated levels of HER-2/ neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.

Published in:

Prostate, 2008, v. 68, n. 8, p. 830, doi. 10.1002/pros.20747

By:

Ricciardelli, Carmela;
Jackson, Michael W.;
Choong, Catherine S.;
Stahl, Jürgen;
Marshall, Villis R.;
Horsfall, David J.;
Tilley, Wayne D.

Publication type:

Article

Changes in steroid receptors and proteoglycan expression in the guinea pig prostate stroma during puberty and hormone manipulation.

Published in:

Prostate, 2007, v. 67, n. 3, p. 288, doi. 10.1002/pros.20524

By:

Sakko, Andrew J.;
Ricciardelli, Carmela;
Mayne, Keiko;
Dours-Zimmermann, Maria T.;
Zimmermann, Dieter R.;
Neufing, Petra;
Tilley, Wayne D.;
Marshall, Villis R.;
Horsfall, David J.

Publication type:

Article

PC‐3 cells with enhanced androgen receptor signaling: A model for clonal selection in prostate cancer.

Published in:

Prostate, 2004, v. 60, n. 4, p. 352, doi. 10.1002/pros.20079

By:

Grant Buchanan;
Paul S. Craft;
Miao Yang;
Albert Cheong;
Jennifer Prescott;
Li Jia;
Gerhard A. Coetzee;
Wayne D. Tilley

Publication type:

Article

Apolipoprotein-D: A novel cellular marker for HGPIN and prostate cancer.

Published in:

Prostate, 2004, v. 58, n. 2, p. 103, doi. 10.1002/pros.10343

By:

R.E. Hall;
D.J. Horsfall;
J. Stahl;
S. Vivekanandan;
C. Ricciardelli;
A.M.F. Stapleton;
P.T. Scardino;
P. Neufing;
Wayne D. Tilley

Publication type:

Article

Glycosaminoglycans of guinea pig prostate fibromuscular stroma: Influence of estrogen and androgen on levels and location of chondroitin sulfate.

Published in:

Prostate, 1994, v. 25, n. 6, p. 320, doi. 10.1002/pros.2990250606

By:

Horsfall, David J.;
Mayne, Keiko;
Skinner, John M.;
Saccone, Gino T. P.;
Marshall, Villis R.;
Tilley, Wayne D.

Publication type:

Article

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 12, p. 5880, doi. 10.1093/nar/gkv262

By:

Siu Chiu Chan;
Selth, Luke A.;
Yingming Li;
Nyquist, Michael D.;
Lu Miao;
Bradner, James E.;
Raj, Ganesh V.;
Tilley, Wayne D.;
Dehm, Scott M.

Publication type:

Article

Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer.

Published in:

Nature Communications, 2013, v. 4, n. 5, p. 1923, doi. 10.1038/ncomms2912

By:

Ravindranathan, Preethi;
Lee, Tae-Kyung;
Yang, Lin;
Centenera, Margaret M.;
Butler, Lisa;
Tilley, Wayne D.;
Hsieh, Jer-Tsong;
Ahn, Jung-Mo;
Raj, Ganesh V.

Publication type:

Article

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice.

Published in:

Scientific Reports, 2016, p. 28950, doi. 10.1038/srep28950

By:

Philp, Lisa K.;
Day, Tanya K.;
Butler, Miriam S.;
Laven-Law, Geraldine;
Jindal, Shalini;
Hickey, Theresa E.;
Scher, Howard I.;
Butler, Lisa M.;
Tilley, Wayne D.

Publication type:

Article

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

Published in:

International Journal of Cancer, 2013, v. 133, n. 12, p. 2812, doi. 10.1002/ijc.28310

By:

Trotta, Andrew P.;
Need, Eleanor F.;
Selth, Luke A.;
Chopra, Samarth;
Pinnock, Carole B.;
Leach, Damien A.;
Coetzee, Gerhard A.;
Butler, Lisa M.;
Tilley, Wayne D.;
Buchanan, Grant

Publication type:

Article

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease.

Published in:

International Journal of Cancer, 2012, v. 131, n. 3, p. 662, doi. 10.1002/ijc.26414

By:

Thompson, Vanessa C.;
Day, Tanya K.;
Bianco-Miotto, Tina;
Selth, Luke A.;
Han, Guangzhou;
Thomas, Mervyn;
Buchanan, Grant;
Scher, Howard I.;
Nelson, Colleen C.;
Greenberg, Norman M.;
Butler, Lisa M.;
Tilley, Wayne D.

Publication type:

Article

Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease.

Published in:

International Journal of Cancer, 2012, v. 131, n. 3, p. 652, doi. 10.1002/ijc.26405

By:

Selth, Luke A.;
Townley, Scott;
Gillis, Joanna L.;
Ochnik, Aleksandra M.;
Murti, Krisna;
Macfarlane, Robyn J.;
Chi, Kim N.;
Marshall, Villis R.;
Tilley, Wayne D.;
Butler, Lisa M.

Publication type:

Article

MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer.

Published in:

2020

By:

Portman, Neil;
Milioli, Heloisa H.;
Alexandrou, Sarah;
Coulson, Rhiannon;
Yong, Aliza;
Fernandez, Kristine J.;
Chia, Kee Ming;
Halilovic, Ensar;
Segara, Davendra;
Parker, Andrew;
Haupt, Sue;
Haupt, Ygal;
Tilley, Wayne D.;
Swarbrick, Alex;
Caldon, C. Elizabeth;
Lim, Elgene

Publication type:

journal article

GSTP1 DNA Methylation and Expression Status Is Indicative of 5-aza-29-Deoxycytidine Efficacy in Human Prostate Cancer Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025634

By:

Chiam, Karen;
Centenera, Margaret M.;
Butler, Lisa M.;
Tilley, Wayne D.;
Bianco-Miotto, Tina

Publication type:

Article

Structural and functional consequences of glutamine tract variation in the androgen receptor.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 16, p. 1677, doi. 10.1093/hmg/ddh181

By:

Buchanan, Grant;
Yang, Miao;
Cheong, Albert;
Harris, Jonathan M.;
Irvine, Ryan A.;
Lambert, Paul F.;
Moore, Nicole L.;
Raynor, Michael;
Neufing, Petra J.;
Coetzee, Gerhard A.;
Tilley, Wayne D.

Publication type:

Article

IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor.

Published in:

2016

By:

Carter, Sarah Louise;
Centenera, Margaret Mary;
Tilley, Wayne Desmond;
Selth, Luke Ashton;
Butler, Lisa Maree;
Carter, Sarah L;
Centenera, Margaret M;
Tilley, Wayne D;
Selth, Luke A;
Butler, Lisa M

Publication type:

journal article

Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2019, v. 24, n. 1, p. 99, doi. 10.1007/s10911-018-9406-2

By:

Tarulli, Gerard A.;
Laven-Law, Geraldine;
Shehata, Mona;
Walters, Kirsty A.;
Denis, Iza M.;
Rahman, Md. Mostafizur;
Handelsman, David J.;
Dean, Nicola R.;
Tilley, Wayne D.;
Hickey, Theresa E.

Publication type:

Article

Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.

Published in:

Cell Cycle, 2012, v. 11, n. 14, p. 2756, doi. 10.4161/cc.21195

By:

Dean, Jeffrey L.;
McClendon, A. Kathleen;
Hickey, Theresa E.;
Butler, Lisa M.;
Tilley, Wayne D.;
Witkiewicz, Agnieszka K.;
Knudsen, Erik S.

Publication type:

Article

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

Published in:

BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-10

By:

Abankwa, Daniel;
Millard, Susan M.;
Martel, Nick;
Choong, Catherine S.;
Miao Yang;
Butler, Lisa M.;
Buchanan, Grant;
Tilley, Wayne D.;
Nobuhide Ueki;
Hayman, Michael J.;
Leong, Gary M.

Publication type:

Article