Works by Tikkanen, Ritva

Results: 72

AP-1 and AP-3 Mediate Sorting of Melanosomal and Lysosomal Membrane Proteins into Distinct Post-Golgi Trafficking Pathways.

Published in:

Traffic, 2008, v. 9, n. 7, p. 1157, doi. 10.1111/j.1600-0854.2008.00745.x

By:

Chapuy, Björn;
Tikkanen, Ritva;
Mühlhausen, Chris;
Wenzel, Dirk;
von Figura, Kurt;
Höning, Stefan

Publication type:

Article

Polarized Transport of Alzheimer Amyloid Precursor Protein Is Mediated by Adaptor Protein Complex AP1-1B.

Published in:

Traffic, 2007, v. 8, n. 3, p. 285, doi. 10.1111/j.1600-0854.2006.00526.x

By:

Icking, Ann;
Amaddii, Monia;
Ruonala, Mika;
Höning, Stefan;
Tikkanen, Ritva

Publication type:

Article

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00664

By:

Zakrzewicz, Anna;
Richter, Katrin;
Zakrzewicz, Dariusz;
Siebers, Kathrin;
Damm, Jelena;
Agné, Alisa;
Hecker, Andreas;
McIntosh, J. Michael;
Chamulitrat, Walee;
Krasteva-Christ, Gabriela;
Manzini, Ivan;
Tikkanen, Ritva;
Padberg, Winfried;
Janciauskiene, Sabina;
Grau, Veronika

Publication type:

Article

Development of precision therapies for rare inborn errors of metabolism: Functional investigations in cell culture models.

Published in:

Journal of Inherited Metabolic Disease, 2024, v. 47, n. 3, p. 509, doi. 10.1002/jimd.12674

By:

Didiasova, Miroslava;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Detailed profile of cognitive dysfunction in children with aspartylglucosaminuria.

Published in:

Journal of Inherited Metabolic Disease, 2020, v. 43, n. 2, p. 318, doi. 10.1002/jimd.12159

By:

Harjunen, Elina Leena;
Laine, Minna;
Tikkanen, Ritva;
Helenius, Päivi

Publication type:

Article

Dsg3 epitope-specific signalling in pemphigus.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1163066

By:

Schmitt, Thomas;
Hudemann, Christoph;
Moztarzadeh, Sina;
Hertl, Michael;
Tikkanen, Ritva;
Waschke, Jens

Publication type:

Article

Regulation of ubiquitin-binding proteins by monoubiquitination.

Published in:

Nature Cell Biology, 2006, v. 8, n. 2, p. 163, doi. 10.1038/ncb1354

By:

Hoeller, Daniela;
Crosetto, Nicola;
Blagoev, Blagoy;
Raiborg, Camilla;
Tikkanen, Ritva;
Wagner, Sebastian;
Kowanetz, Katarzyna;
Breitling, Rainer;
Mann, Matthias;
Stenmark, Harald;
Dikic, Ivan

Publication type:

Article

AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells.

Published in:

Nature Cell Biology, 2002, v. 4, n. 2, p. 154, doi. 10.1038/ncb745

By:

Simmen, Thomas;
Höning, Stefan;
Icking, Ann;
Tikkanen, Ritva;
Hunziker, Walter

Publication type:

Article

Large-scale purification and preliminary X-ray diffraction studies of human aspartylglucosaminidase.

Published in:

Proteins, 1996, v. 24, n. 2, p. 253, doi. 10.1002/(SICI)1097-0134(199602)24:2<253::AID-PROT12>3.0.CO;2-M

By:

Tikkanen, Ritva;
Rouvinen, Juha;
Törrönen, Anneli;
Kalkkinen, Nisse;
Peltonen, Leena

Publication type:

Article

Role of dynamin and clathrin in the cellular trafficking of flotillins.

Published in:

FEBS Journal, 2014, v. 281, n. 13, p. 2956, doi. 10.1111/febs.12834

By:

Meister, Melanie;
Zuk, Alexandra;
Tikkanen, Ritva

Publication type:

Article

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.

Published in:

FEBS Journal, 2014, v. 281, n. 8, p. 2074, doi. 10.1111/febs.12763

By:

John, Bincy A.;
Meister, Melanie;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Cytosolic and nuclear aggregation of the amyloid β-peptide following its expression in the endoplasmic reticulum.

Published in:

Histochemistry & Cell Biology, 2002, v. 118, n. 5, p. 353, doi. 10.1007/s00418-002-0459-2

By:

Bückig, Andrea;
Tikkanen, Ritva;
Herzog, Volker;
Schmitz, Anton

Publication type:

Article

Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells.

Published in:

2013

By:

Kurrle, Nina;
Ockenga, Wymke;
Meister, Melanie;
Völlner, Frauke;
Kühne, Sina;
John, Bincy A.;
Banning, Antje;
Tikkanen1, Ritva;
Tikkanen, Ritva

Publication type:

journal article

Binding to the neonatal Fc receptor enhances the pathogenicity of antidesmoglein-3 antibodies in keratinocytes.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1473637

By:

Zakrzewicz, Anna;
Vanderheyden, Katrien;
Galaly, Yad;
Feldhoff, Simon;
Sips, Magdalena;
Brinkhaus, Maximilian;
Tikkanen, Ritva

Publication type:

Article

Quality-controlled characterization of a monoclonal antibody specific to an EC5-domain of human desmoglein 3 for pemphigus research.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1464881

By:

Eming, Rüdiger;
Riaz, Shafaq;
Müller, Eliane J.;
Zakrzewicz, Anna;
Linne, Uwe;
Tikkanen, Ritva;
Lea Zimmer, Christine;
Hudemann, Christoph

Publication type:

Article

Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase.

Published in:

EMBO Journal, 1997, v. 16, n. 22, p. 6684, doi. 10.1093/emboj/16.22.6684

By:

Tikkanen, Ritva;
Peltola, Minna;
Oinonen, Carita;
Rouvinen, Juha;
Peltonen, Leena

Publication type:

Article

Functional Characterization of a Spectrum of Genetic Variants in a Family with Succinic Semialdehyde Dehydrogenase Deficiency.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5237, doi. 10.3390/ijms25105237

By:

Didiasova, Miroslava;
Cesaro, Samuele;
Feldhoff, Simon;
Bettin, Ilaria;
Tiegel, Nana;
Füssgen, Vera;
Bertoldi, Mariarita;
Tikkanen, Ritva

Publication type:

Article

Validation of Aspartylglucosaminidase Activity Assay for Human Serum Samples: Establishment of a Biomarker for Diagnostics and Clinical Studies.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5722, doi. 10.3390/ijms24065722

By:

Banning, Antje;
Laine, Minna;
Tikkanen, Ritva

Publication type:

Article

Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development–Review.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2935, doi. 10.3390/ijms22062935

By:

Łukasik, Paweł;
Załuski, Michał;
Gutowska, Izabela;
Tikkanen, Ritva

Publication type:

Article

Gene Expression-Related Changes in Morphologies of Organelles and Cellular Component Organization in Mucopolysaccharidoses.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2766, doi. 10.3390/ijms22052766

By:

Gaffke, Lidia;
Pierzynowska, Karolina;
Rintz, Estera;
Cyske, Zuzanna;
Giecewicz, Izabela;
Węgrzyn, Grzegorz;
Tikkanen, Ritva

Publication type:

Article

Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8578, doi. 10.3390/ijms21228578

By:

Brennenstuhl, Heiko;
Didiasova, Miroslava;
Assmann, Birgit;
Bertoldi, Mariarita;
Molla, Gianluca;
Jung-Klawitter, Sabine;
Kuseyri Hübschmann, Oya;
Schröter, Julian;
Opladen, Thomas;
Tikkanen, Ritva

Publication type:

Article

Mitogen-Activated Protein Kinases: Functions in Signal Transduction and Human Diseases.

Published in:

2019

By:

Tikkanen, Ritva;
Nikolic-Paterson, David J.

Publication type:

Editorial

Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 13, p. 3113, doi. 10.3390/ijms20133113

By:

Beckert, Benedikt;
Panico, Francesca;
Pollmann, Robert;
Eming, Rüdiger;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Altered Expression of Ganglioside Metabolizing Enzymes Results in GM3 Ganglioside Accumulation in Cerebellar Cells of a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 625, doi. 10.3390/ijms19020625

By:

Somogyi, Aleksandra;
Petcherski, Anton;
Beckert, Benedikt;
Huebecker, Mylene;
Priestman, David A.;
Banning, Antje;
Cotman, Susan L.;
Platt, Frances M.;
Ruonala, Mika O.;
Tikkanen, Ritva

Publication type:

Article

Functional Analysis of the Ser149/Thr149 Variants of Human Aspartylglucosaminidase and Optimization of the Coding Sequence for Protein Production.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 4, p. 706, doi. 10.3390/ijms18040706

By:

Banning, Antje;
König, Jan F.;
Gray, Steven J.;
Tikkanen, Ritva

Publication type:

Article

Cholinergic Transactivation of the EGFR in HaCaT Keratinocytes Stimulates a Flotillin-1 Dependent MAPK-Mediated Transcriptional Response.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 3, p. 6447, doi. 10.3390/ijms16036447

By:

Kühne, Sina;
Ockenga, Wymke;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Epidermal Growth Factor Receptor Transactivation Is Required for Mitogen-Activated Protein Kinase Activation by Muscarinic Acetylcholine Receptors in HaCaT Keratinocytes.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 11, p. 21433, doi. 10.3390/ijms151121433

By:

Ockenga, Wymke;
Kühne, Sina;
Bocksberger, Simone;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 3, p. 4854, doi. 10.3390/ijms14034854

By:

Meister, Melanie;
Tomasovic, Ana;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Revisiting the Endocytosis of the M<sub>2</sub> Muscarinic Acetylcholine Receptor.

Published in:

Membranes, 2015, v. 5, n. 2, p. 197, doi. 10.3390/membranes5020197

By:

Ockenga, Wymke;
Tikkanen, Ritva

Publication type:

Article

Endocytic Trafficking of Membrane-Bound Cargo: A Flotillin Point of View.

Published in:

Membranes, 2014, v. 4, n. 3, p. 356, doi. 10.3390/membranes4030356

By:

Meister, Melanie;
Tikkanen, Ritva

Publication type:

Article

Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration.

Published in:

Science Signaling, 2014, v. 7, n. 337, p. 1, doi. 10.1126/scisignal.2005484

By:

Mooz, Juliane;
Oberoi-Khanuja, Tripat Kaur;
Harms, Gregory S.;
Weiru Wang;
Jaiswal, Bijay S.;
Seshagiri, Somasekar;
Tikkanen, Ritva;
Rajalingam, Krishnaraj

Publication type:

Article

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes.

Published in:

Traffic, 2000, v. 1, n. 8, p. 631, doi. 10.1034/j.1600-0854.2000.010807.x

By:

Tikkanen, Ritva;
Obermüller, Stefanie;
Denzer, Kristin;
Pungitore, Rodolfo;
Geuze, Hans J.;
von Figura, Kurt;
Höning, Stefan

Publication type:

Article

Identification of Small Molecule Compounds for Pharmacological Chaperone Therapy of Aspartylglucosaminuria.

Published in:

Scientific Reports, 2016, p. 37583, doi. 10.1038/srep37583

By:

Banning, Antje;
Gülec, Christina;
Rouvinen, Juha;
Gray, Steven J.;
Tikkanen, Ritva

Publication type:

Article

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes.

Published in:

Scientific Reports, 2016, p. 28820, doi. 10.1038/srep28820

By:

Völlner, Frauke;
Ali, Jawahir;
Kurrle, Nina;
Exner, Yvonne;
Eming, Rüdiger;
Hertl, Michael;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Editorial: Pharmacology of gangliosides.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1449928

By:

Hongda Zhuang;
Zhendong Huang;
Birklé, Stéphane;
Chammas, Roger;
Tikkanen, Ritva;
Yong Chen

Publication type:

Article

Flotillins Directly Interact with γ-Catenin and Regulate Epithelial Cell-Cell Adhesion.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084393

By:

Kurrle, Nina;
Völlner, Frauke;
Eming, Rüdiger;
Hertl, Michael;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Transcriptional Regulation of Flotillins by the Extracellularly Regulated Kinases and Retinoid X Receptor Complexes.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045514

By:

Banning, Antje;
Ockenga, Wymke;
Finger, Fabian;
Siebrasse, Philipp;
Tikkanen, Ritva;
Buday, Laszlo

Publication type:

Article

Molecular Networks in FGF Signaling: Flotillin-1 and Cbl-Associated Protein Compete for the Binding to Fibroblast Growth Factor Receptor Substrate 2.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029739

By:

Tomasovic, Ana;
Traub, Stephanie;
Tikkanen, Ritva

Publication type:

Article

Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney.

Published in:

Kidney International, 2008, v. 74, n. 3, p. 328, doi. 10.1038/ki.2008.181

By:

Schramme, Anja;
Abdel-Bakky, Mohamed Sadek;
Gutwein, Paul;
Obermüller, Nicholas;
Baer, Patrick C.;
Hauser, Ingeborg A.;
Ludwig, Andreas;
Gauer, Stefan;
Schäfer, Liliana;
Sobkowiak, Ewelina;
Altevogt, Peter;
Koziolek, Michael;
Kiss, Eva;
Gröne, Hermann-Josef;
Tikkanen, Ritva;
Goren, Itamar;
Radeke, Heinfried;
Pfeilschifter, Josef

Publication type:

Article

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells.

Published in:

Basic Research in Cardiology, 2014, v. 109, n. 6, p. 1, doi. 10.1007/s00395-014-0439-4

By:

Fork, Christian;
Hitzel, Juliane;
Nichols, Benjamin J.;
Tikkanen, Ritva;
Brandes, Ralf P.

Publication type:

Article

Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells 2022, 11 , 942.

Published in:

2022

By:

Zakrzewicz, Anna;
Würth, Celina;
Beckert, Benedikt;
Feldhoff, Simon;
Vanderheyden, Katrien;
Foss, Stian;
Andersen, Jan Terje;
Haard, Hans de;
Verheesen, Peter;
Bobkov, Vladimir;
Tikkanen, Ritva

Publication type:

Correction Notice

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

Published in:

Cells (2073-4409), 2022, v. 11, n. 6, p. 942, doi. 10.3390/cells11060942

By:

Zakrzewicz, Anna;
Würth, Celina;
Beckert, Benedikt;
Feldhoff, Simon;
Vanderheyden, Katrien;
Foss, Stian;
Andersen, Jan Terje;
Haard, Hans de;
Verheesen, Peter;
Bobkov, Vladimir;
Tikkanen, Ritva

Publication type:

Article

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

Published in:

Cells (2073-4409), 2022, v. 11, n. 2, p. 292, doi. 10.3390/cells11020292

By:

Clees, Ada-Sophia;
Stolp, Verena;
Häupl, Björn;
Fuhrmann, Dominik C.;
Wempe, Frank;
Seibert, Marcel;
Weber, Sarah;
Banning, Antje;
Tikkanen, Ritva;
Williams, Richard;
Brüne, Bernhard;
Serve, Hubert;
Schnütgen, Frank;
von Metzler, Ivana;
Kurrle, Nina

Publication type:

Article

A Journey towards Understanding the Molecular Pathology and Developing Therapies for Lysosomal Storage Disorders.

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 36, doi. 10.3390/cells11010036

By:

Tikkanen, Ritva

Publication type:

Article

Towards Splicing Therapy for Lysosomal Storage Disorders: Methylxanthines and Luteolin Ameliorate Splicing Defects in Aspartylglucosaminuria and Classic Late Infantile Neuronal Ceroid Lipofuscinosis.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2813, doi. 10.3390/cells10112813

By:

Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Knockout of the CMP–Sialic Acid Transporter SLC35A1 in Human Cell Lines Increases Transduction Efficiency of Adeno-Associated Virus 9: Implications for Gene Therapy Potency Assays.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1259, doi. 10.3390/cells10051259

By:

Banning, Antje;
Zakrzewicz, Anna;
Chen, Xin;
Gray, Steven J.;
Tikkanen, Ritva;
Brakebusch, Cord;
d'Azzo, Alessandra

Publication type:

Article

HDL in Immune-Inflammatory Responses: Implications beyond Cardiovascular Diseases.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1061, doi. 10.3390/cells10051061

By:

Bonacina, Fabrizia;
Pirillo, Angela;
Catapano, Alberico L.;
Norata, Giuseppe D.;
Tikkanen, Ritva

Publication type:

Article

Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1035, doi. 10.3390/cells10051035

By:

Ouyang, Yulin;
Wen, Li;
Armstrong, Jane A.;
Chvanov, Michael;
Latawiec, Diane;
Cai, Wenhao;
Awais, Mohammad;
Mukherjee, Rajarshi;
Huang, Wei;
Gough, Peter J.;
Bertin, John;
Tepikin, Alexei V.;
Sutton, Robert;
Criddle, David N.;
Bultynck, Geert;
Tikkanen, Ritva

Publication type:

Article

Precision Oncology Beyond Genomics: The Future Is Here—It Is Just Not Evently Distributed.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 928, doi. 10.3390/cells10040928

By:

Pfohl, Ulrike;
Pflaume, Alina;
Regenbrecht, Manuela;
Finkler, Sabine;
Graf Adelmann, Quirin;
Reinhard, Christoph;
Regenbrecht, Christian R. A.;
Wedeken, Lena;
Tikkanen, Ritva

Publication type:

Article

Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 866, doi. 10.3390/cells10040866

By:

Spyropoulou, Zoi;
Papaspyropoulos, Angelos;
Lagopati, Nefeli;
Myrianthopoulos, Vassilios;
Georgakilas, Alexandros G.;
Fousteri, Maria;
Kotsinas, Athanassios;
Gorgoulis, Vassilis G.;
Tikkanen, Ritva

Publication type:

Article