Works matching AU Tikkanen, Ritva

Results: 72

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells.

Published in:

Basic Research in Cardiology, 2014, v. 109, n. 6, p. 1, doi. 10.1007/s00395-014-0439-4

By:

Fork, Christian;
Hitzel, Juliane;
Nichols, Benjamin J.;
Tikkanen, Ritva;
Brandes, Ralf P.

Publication type:

Article

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00664

By:

Zakrzewicz, Anna;
Richter, Katrin;
Zakrzewicz, Dariusz;
Siebers, Kathrin;
Damm, Jelena;
Agné, Alisa;
Hecker, Andreas;
McIntosh, J. Michael;
Chamulitrat, Walee;
Krasteva-Christ, Gabriela;
Manzini, Ivan;
Tikkanen, Ritva;
Padberg, Winfried;
Janciauskiene, Sabina;
Grau, Veronika

Publication type:

Article

Non-Neuronal Functions of the M<sub>2</sub> Muscarinic Acetylcholine Receptor.

Published in:

Genes, 2013, v. 4, n. 2, p. 171, doi. 10.3390/genes4020171

By:

Ockenga, Wymke;
Kühne, Sina;
Bocksberger, Simone;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells.

Published in:

2013

By:

Kurrle, Nina;
Ockenga, Wymke;
Meister, Melanie;
Völlner, Frauke;
Kühne, Sina;
John, Bincy A.;
Banning, Antje;
Tikkanen1, Ritva;
Tikkanen, Ritva

Publication type:

journal article

Cytosolic and nuclear aggregation of the amyloid β-peptide following its expression in the endoplasmic reticulum.

Published in:

Histochemistry & Cell Biology, 2002, v. 118, n. 5, p. 353, doi. 10.1007/s00418-002-0459-2

By:

Bückig, Andrea;
Tikkanen, Ritva;
Herzog, Volker;
Schmitz, Anton

Publication type:

Article

Succinic Semialdehyde Dehydrogenase Deficiency: An Update.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 477, doi. 10.3390/cells9020477

By:

Didiasova, Miroslava;
Banning, Antje;
Brennenstuhl, Heiko;
Jung-Klawitter, Sabine;
Cinquemani, Claudio;
Opladen, Thomas;
Tikkanen, Ritva

Publication type:

Article

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase.

Published in:

Cells (2073-4409), 2018, v. 7, n. 4, p. 28, doi. 10.3390/cells7040028

By:

Banning, Antje;
Babuke, Tanja;
Kurrle, Nina;
Meister, Melanie;
Ruonala, Mika O.;
Tikkanen, Ritva

Publication type:

Article

Random Splicing of Several Exons Caused by a Single Base Change in the Target Exon of CRISPR/Cas9 Mediated Gene Knockout.

Published in:

Cells (2073-4409), 2016, v. 5, n. 4, p. 45, doi. 10.3390/cells5040045

By:

Kapahnke, Marcel;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Flotillins in Receptor Tyrosine Kinase Signaling and Cancer.

Published in:

Cells (2073-4409), 2014, v. 3, n. 1, p. 129, doi. 10.3390/cells3010129

By:

Banning, Antje;
Kurrle, Nina;
Meister, Melanie;
Tikkanen, Ritva

Publication type:

Article

Detection of Aspartylglucosaminuria Patients from Magnetic Resonance Images by a Machine-Learning-Based Approach.

Published in:

Brain Sciences (2076-3425), 2022, v. 12, n. 11, p. 1522, doi. 10.3390/brainsci12111522

By:

Ruohola, Arttu;
Salli, Eero;
Roine, Timo;
Tokola, Anna;
Laine, Minna;
Tikkanen, Ritva;
Savolainen, Sauli;
Autti, Taina

Publication type:

Article

Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria.

Published in:

Brain Sciences (2076-3425), 2020, v. 10, n. 10, p. 677, doi. 10.3390/brainsci10100677

By:

Sairanen, Viljami;
Tokola, Anna;
Tikkanen, Ritva;
Laine, Minna;
Autti, Taina

Publication type:

Article

Editorial: Pharmacology of gangliosides.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1449928

By:

Hongda Zhuang;
Zhendong Huang;
Birklé, Stéphane;
Chammas, Roger;
Tikkanen, Ritva;
Yong Chen

Publication type:

Article

Binding to the neonatal Fc receptor enhances the pathogenicity of antidesmoglein-3 antibodies in keratinocytes.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1473637

By:

Zakrzewicz, Anna;
Vanderheyden, Katrien;
Galaly, Yad;
Feldhoff, Simon;
Sips, Magdalena;
Brinkhaus, Maximilian;
Tikkanen, Ritva

Publication type:

Article

Quality-controlled characterization of a monoclonal antibody specific to an EC5-domain of human desmoglein 3 for pemphigus research.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1464881

By:

Eming, Rüdiger;
Riaz, Shafaq;
Müller, Eliane J.;
Zakrzewicz, Anna;
Linne, Uwe;
Tikkanen, Ritva;
Lea Zimmer, Christine;
Hudemann, Christoph

Publication type:

Article

Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration.

Published in:

Science Signaling, 2014, v. 7, n. 337, p. 1, doi. 10.1126/scisignal.2005484

By:

Mooz, Juliane;
Oberoi-Khanuja, Tripat Kaur;
Harms, Gregory S.;
Weiru Wang;
Jaiswal, Bijay S.;
Seshagiri, Somasekar;
Tikkanen, Ritva;
Rajalingam, Krishnaraj

Publication type:

Article

Flotillins Directly Interact with γ-Catenin and Regulate Epithelial Cell-Cell Adhesion.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084393

By:

Kurrle, Nina;
Völlner, Frauke;
Eming, Rüdiger;
Hertl, Michael;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Transcriptional Regulation of Flotillins by the Extracellularly Regulated Kinases and Retinoid X Receptor Complexes.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045514

By:

Banning, Antje;
Ockenga, Wymke;
Finger, Fabian;
Siebrasse, Philipp;
Tikkanen, Ritva;
Buday, Laszlo

Publication type:

Article

Molecular Networks in FGF Signaling: Flotillin-1 and Cbl-Associated Protein Compete for the Binding to Fibroblast Growth Factor Receptor Substrate 2.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029739

By:

Tomasovic, Ana;
Traub, Stephanie;
Tikkanen, Ritva

Publication type:

Article

Identification of Small Molecule Compounds for Pharmacological Chaperone Therapy of Aspartylglucosaminuria.

Published in:

Scientific Reports, 2016, p. 37583, doi. 10.1038/srep37583

By:

Banning, Antje;
Gülec, Christina;
Rouvinen, Juha;
Gray, Steven J.;
Tikkanen, Ritva

Publication type:

Article

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes.

Published in:

Scientific Reports, 2016, p. 28820, doi. 10.1038/srep28820

By:

Völlner, Frauke;
Ali, Jawahir;
Kurrle, Nina;
Exner, Yvonne;
Eming, Rüdiger;
Hertl, Michael;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Revisiting the Endocytosis of the M<sub>2</sub> Muscarinic Acetylcholine Receptor.

Published in:

Membranes, 2015, v. 5, n. 2, p. 197, doi. 10.3390/membranes5020197

By:

Ockenga, Wymke;
Tikkanen, Ritva

Publication type:

Article

Endocytic Trafficking of Membrane-Bound Cargo: A Flotillin Point of View.

Published in:

Membranes, 2014, v. 4, n. 3, p. 356, doi. 10.3390/membranes4030356

By:

Meister, Melanie;
Tikkanen, Ritva

Publication type:

Article

Defective intracellular transport of CLN3 is the molecular basis of Batten disease (JNCL).

Published in:

Human Molecular Genetics, 1999, v. 8, n. 6, p. 1091, doi. 10.1093/hmg/8.6.1091

By:

Jarvela, Irma;
Lehtovirta, Maarit;
Tikkanen, Ritva;
Kyttaia, Aija;
Jalanko, Anu

Publication type:

Article

Ser72Pro Active-Site Disease Mutation in Human Lysosomal Aspartylglucosaminidase: Abnormal Intracellular Processing and Evidence for Extracellular Activation.

Published in:

Human Molecular Genetics, 1996, v. 5, n. 6, p. 737, doi. 10.1093/hmg/5.6.737

By:

Peltola, Minna;
Tikkanen, Ritva;
Peltonen, Leena;
Jalanko, Anu

Publication type:

Article

Oncogenic breakdowns in endocytic adaptor proteins

Published in:

FEBS Letters, 2005, v. 579, n. 15, p. 3231, doi. 10.1016/j.febslet.2005.03.029

By:

Crosetto, Nicola;
Tikkanen, Ritva;
Dikic, Ivan

Publication type:

Article

Large-scale purification and preliminary X-ray diffraction studies of human aspartylglucosaminidase.

Published in:

Proteins, 1996, v. 24, n. 2, p. 253, doi. 10.1002/(SICI)1097-0134(199602)24:2<253::AID-PROT12>3.0.CO;2-M

By:

Tikkanen, Ritva;
Rouvinen, Juha;
Törrönen, Anneli;
Kalkkinen, Nisse;
Peltonen, Leena

Publication type:

Article

Intracellular Sorting of Aspartylglucosaminidase: The Role of N-Linked Oligosaccharides and Evidence of Man-6-P-Independent Lysosomal Targeting.

Published in:

DNA & Cell Biology, 1995, v. 14, n. 4, p. 305, doi. 10.1089/dna.1995.14.305

By:

TIKKANEN, RITVA;
ENOMAA, NINA;
RIIKONEN, AIJA;
IKONEN, ELINA;
PELTONEN, LEENA

Publication type:

Article

Development of precision therapies for rare inborn errors of metabolism: Functional investigations in cell culture models.

Published in:

Journal of Inherited Metabolic Disease, 2024, v. 47, n. 3, p. 509, doi. 10.1002/jimd.12674

By:

Didiasova, Miroslava;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Detailed profile of cognitive dysfunction in children with aspartylglucosaminuria.

Published in:

Journal of Inherited Metabolic Disease, 2020, v. 43, n. 2, p. 318, doi. 10.1002/jimd.12159

By:

Harjunen, Elina Leena;
Laine, Minna;
Tikkanen, Ritva;
Helenius, Päivi

Publication type:

Article

Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase.

Published in:

EMBO Journal, 1997, v. 16, n. 22, p. 6684, doi. 10.1093/emboj/16.22.6684

By:

Tikkanen, Ritva;
Peltola, Minna;
Oinonen, Carita;
Rouvinen, Juha;
Peltonen, Leena

Publication type:

Article

AP-1 and AP-3 Mediate Sorting of Melanosomal and Lysosomal Membrane Proteins into Distinct Post-Golgi Trafficking Pathways.

Published in:

Traffic, 2008, v. 9, n. 7, p. 1157, doi. 10.1111/j.1600-0854.2008.00745.x

By:

Chapuy, Björn;
Tikkanen, Ritva;
Mühlhausen, Chris;
Wenzel, Dirk;
von Figura, Kurt;
Höning, Stefan

Publication type:

Article

Polarized Transport of Alzheimer Amyloid Precursor Protein Is Mediated by Adaptor Protein Complex AP1-1B.

Published in:

Traffic, 2007, v. 8, n. 3, p. 285, doi. 10.1111/j.1600-0854.2006.00526.x

By:

Icking, Ann;
Amaddii, Monia;
Ruonala, Mika;
Höning, Stefan;
Tikkanen, Ritva

Publication type:

Article

Role of dynamin and clathrin in the cellular trafficking of flotillins.

Published in:

FEBS Journal, 2014, v. 281, n. 13, p. 2956, doi. 10.1111/febs.12834

By:

Meister, Melanie;
Zuk, Alexandra;
Tikkanen, Ritva

Publication type:

Article

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.

Published in:

FEBS Journal, 2014, v. 281, n. 8, p. 2074, doi. 10.1111/febs.12763

By:

John, Bincy A.;
Meister, Melanie;
Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes.

Published in:

Traffic, 2000, v. 1, n. 8, p. 631, doi. 10.1034/j.1600-0854.2000.010807.x

By:

Tikkanen, Ritva;
Obermüller, Stefanie;
Denzer, Kristin;
Pungitore, Rodolfo;
Geuze, Hans J.;
von Figura, Kurt;
Höning, Stefan

Publication type:

Article

Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells 2022, 11 , 942.

Published in:

2022

By:

Zakrzewicz, Anna;
Würth, Celina;
Beckert, Benedikt;
Feldhoff, Simon;
Vanderheyden, Katrien;
Foss, Stian;
Andersen, Jan Terje;
Haard, Hans de;
Verheesen, Peter;
Bobkov, Vladimir;
Tikkanen, Ritva

Publication type:

Correction Notice

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

Published in:

Cells (2073-4409), 2022, v. 11, n. 6, p. 942, doi. 10.3390/cells11060942

By:

Zakrzewicz, Anna;
Würth, Celina;
Beckert, Benedikt;
Feldhoff, Simon;
Vanderheyden, Katrien;
Foss, Stian;
Andersen, Jan Terje;
Haard, Hans de;
Verheesen, Peter;
Bobkov, Vladimir;
Tikkanen, Ritva

Publication type:

Article

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

Published in:

Cells (2073-4409), 2022, v. 11, n. 2, p. 292, doi. 10.3390/cells11020292

By:

Clees, Ada-Sophia;
Stolp, Verena;
Häupl, Björn;
Fuhrmann, Dominik C.;
Wempe, Frank;
Seibert, Marcel;
Weber, Sarah;
Banning, Antje;
Tikkanen, Ritva;
Williams, Richard;
Brüne, Bernhard;
Serve, Hubert;
Schnütgen, Frank;
von Metzler, Ivana;
Kurrle, Nina

Publication type:

Article

A Journey towards Understanding the Molecular Pathology and Developing Therapies for Lysosomal Storage Disorders.

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 36, doi. 10.3390/cells11010036

By:

Tikkanen, Ritva

Publication type:

Article

Towards Splicing Therapy for Lysosomal Storage Disorders: Methylxanthines and Luteolin Ameliorate Splicing Defects in Aspartylglucosaminuria and Classic Late Infantile Neuronal Ceroid Lipofuscinosis.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2813, doi. 10.3390/cells10112813

By:

Banning, Antje;
Tikkanen, Ritva

Publication type:

Article

Knockout of the CMP–Sialic Acid Transporter SLC35A1 in Human Cell Lines Increases Transduction Efficiency of Adeno-Associated Virus 9: Implications for Gene Therapy Potency Assays.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1259, doi. 10.3390/cells10051259

By:

Banning, Antje;
Zakrzewicz, Anna;
Chen, Xin;
Gray, Steven J.;
Tikkanen, Ritva;
Brakebusch, Cord;
d'Azzo, Alessandra

Publication type:

Article

HDL in Immune-Inflammatory Responses: Implications beyond Cardiovascular Diseases.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1061, doi. 10.3390/cells10051061

By:

Bonacina, Fabrizia;
Pirillo, Angela;
Catapano, Alberico L.;
Norata, Giuseppe D.;
Tikkanen, Ritva

Publication type:

Article

Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1035, doi. 10.3390/cells10051035

By:

Ouyang, Yulin;
Wen, Li;
Armstrong, Jane A.;
Chvanov, Michael;
Latawiec, Diane;
Cai, Wenhao;
Awais, Mohammad;
Mukherjee, Rajarshi;
Huang, Wei;
Gough, Peter J.;
Bertin, John;
Tepikin, Alexei V.;
Sutton, Robert;
Criddle, David N.;
Bultynck, Geert;
Tikkanen, Ritva

Publication type:

Article

Precision Oncology Beyond Genomics: The Future Is Here—It Is Just Not Evently Distributed.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 928, doi. 10.3390/cells10040928

By:

Pfohl, Ulrike;
Pflaume, Alina;
Regenbrecht, Manuela;
Finkler, Sabine;
Graf Adelmann, Quirin;
Reinhard, Christoph;
Regenbrecht, Christian R. A.;
Wedeken, Lena;
Tikkanen, Ritva

Publication type:

Article

Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 866, doi. 10.3390/cells10040866

By:

Spyropoulou, Zoi;
Papaspyropoulos, Angelos;
Lagopati, Nefeli;
Myrianthopoulos, Vassilios;
Georgakilas, Alexandros G.;
Fousteri, Maria;
Kotsinas, Athanassios;
Gorgoulis, Vassilis G.;
Tikkanen, Ritva

Publication type:

Article

Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 849, doi. 10.3390/cells10040849

By:

Paget, Tamara L.;
Parkinson-Lawrence, Emma J.;
Trim, Paul J.;
Autilio, Chiara;
Panchal, Madhuriben H.;
Koster, Grielof;
Echaide, Mercedes;
Snel, Marten F.;
Postle, Anthony D.;
Morrison, Janna L.;
Pérez-Gil, Jésus;
Orgeig, Sandra;
Tikkanen, Ritva

Publication type:

Article

Artificial Intelligence & Tissue Biomarkers: Advantages, Risks and Perspectives for Pathology.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 787, doi. 10.3390/cells10040787

By:

Lancellotti, Cesare;
Cancian, Pierandrea;
Savevski, Victor;
Kotha, Soumya Rupa Reddy;
Fraggetta, Filippo;
Graziano, Paolo;
Di Tommaso, Luca;
Tikkanen, Ritva

Publication type:

Article

Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 766, doi. 10.3390/cells10040766

By:

Sève, Pascal;
Pacheco, Yves;
Durupt, François;
Jamilloux, Yvan;
Gerfaud-Valentin, Mathieu;
Isaac, Sylvie;
Boussel, Loïc;
Calender, Alain;
Androdias, Géraldine;
Valeyre, Dominique;
El Jammal, Thomas;
Tikkanen, Ritva

Publication type:

Article

Energy Metabolism in IDH1 Wild-Type and IDH1 -Mutated Glioblastoma Stem Cells: A Novel Target for Therapy?

Published in:

Cells (2073-4409), 2021, v. 10, n. 3, p. 705, doi. 10.3390/cells10030705

By:

van Noorden, Cornelis J.F.;
Hira, Vashendriya V.V.;
van Dijck, Amber J.;
Novak, Metka;
Breznik, Barbara;
Molenaar, Remco J.;
Castresana, Javier S.;
Tikkanen, Ritva

Publication type:

Article

The Uncovered Function of the Drosophila GBA1a -Encoded Protein.

Published in:

Cells (2073-4409), 2021, v. 10, n. 3, p. 630, doi. 10.3390/cells10030630

By:

Cabasso, Or;
Paul, Sumit;
Maor, Gali;
Pasmanik-Chor, Metsada;
Kallemeijn, Wouter;
Aerts, Johannes;
Horowitz, Mia;
Tikkanen, Ritva

Publication type:

Article