Works by Tikhonov, Denis B.

Results: 27

The diversity of AMPA receptor inhibition mechanisms among amidine-containing compounds.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1467266

By:

Zhigulin, Arseniy S.;
Dron, Mikhail Y.;
Barygin, Oleg I.;
Tikhonov, Denis B.

Publication type:

Article

Possible Compensatory Role of ASICs in Glutamatergic Synapses.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12974, doi. 10.3390/ijms241612974

By:

Evlanenkov, Konstantin K.;
Zhigulin, Arseniy S.;
Tikhonov, Denis B.

Publication type:

Article

Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8143, doi. 10.3390/ijms22158143

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Hydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1713, doi. 10.3390/ijms20071713

By:

Shteinikov, Vasilii Y;
Potapieva, Natalia N;
Tikhonov, Denis B;
Gmiro, Valery E

Publication type:

Article

TRPV1 activation power can switch an action mode for its polypeptide ligands.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177077

By:

Nikolaev, Maxim V.;
Dorofeeva, Natalia A.;
Komarova, Margarita S.;
Korolkova, Yuliya V.;
Andreev, Yaroslav A.;
Mosharova, Irina V.;
Grishin, Eugene V.;
Tikhonov, Denis B.;
Kozlov, Sergey A.

Publication type:

Article

Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine

Published in:

FEBS Letters, 2006, v. 580, n. 26, p. 6027, doi. 10.1016/j.febslet.2006.10.035

By:

Tikhonov, Denis B.;
Bruhova, Iva;
Zhorov, Boris S.

Publication type:

Article

Sodium channel activators: Model of binding inside the pore and a possible mechanism of action

Published in:

FEBS Letters, 2005, v. 579, n. 20, p. 4207, doi. 10.1016/j.febslet.2005.07.017

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Probing the Proton-Gated ASIC Channels Using Tetraalkylammonium Ions.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 11, p. 1631, doi. 10.3390/biom13111631

By:

Evlanenkov, Konstantin K.;
Nikolaev, Maxim V.;
Potapieva, Natalia N.;
Bolshakov, Konstantin V.;
Tikhonov, Denis B.

Publication type:

Article

The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1725, doi. 10.1002/cmdc.201402109

By:

Franzyk, Henrik;
Grzeskowiak, John W.;
Tikhonov, Denis B.;
Jaroszewski, Jerzy W.;
Mellor, Ian R.

Publication type:

Article

Modulation of Slow Desensitization (Tachyphylaxis) of Acid-Sensing Ion Channel (ASIC)1a.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 2, p. 771, doi. 10.1007/s10571-022-01207-6

By:

Komarova, Margarita S.;
Bukharev, Andrey R.;
Potapieva, Natalia N.;
Tikhonov, Denis B.

Publication type:

Article

Potentiation and Block of ASIC1a by Memantine.

Published in:

Cellular & Molecular Neurobiology, 2018, v. 38, n. 4, p. 869, doi. 10.1007/s10571-017-0561-6

By:

Shteinikov, Vasiliy Y.;
Tikhonova, Tatiana B.;
Korkosh, Vyacheslav S.;
Tikhonov, Denis B.

Publication type:

Article

Voltage-dependent and -independent block of α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor channels.

Published in:

Journal of Neurochemistry, 2010, v. 115, n. 6, p. 1621, doi. 10.1111/j.1471-4159.2010.07068.x

By:

Barygin, Oleg I.;
Luchkina, Natalia V.;
Tikhonov, Denis B.

Publication type:

Article

REVIEW Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action.

Published in:

Journal of Neurochemistry, 2004, v. 88, n. 4, p. 782, doi. 10.1111/j.1471-4159.2004.02261.x

By:

Zhorov, Boris S.;
Tikhonov, Denis B.

Publication type:

Article

Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action.

Published in:

Journal of Neurochemistry, 2004, v. 88, n. 3, p. 782, doi. 10.1111/j.1471-4159.2004.02261.x

By:

Zhorov, Boris S.;
Tikhonov, Denis B.

Publication type:

Article

Phenylalkylamines in calcium channels: computational analysis of experimental structures.

Published in:

Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 11, p. 1157, doi. 10.1007/s10822-020-00330-0

By:

Tikhonov, Denis B.;
Lin, Lianyun;
Yang, Daniel S. C.;
Yuchi, Zhiguang;
Zhorov, Boris S.

Publication type:

Article

Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.

Published in:

Invertebrate Neuroscience, 2019, v. 19, n. 1, p. 1, doi. 10.1007/s10158-019-0224-z

By:

Fedorova, Irina M.;
Tikhonov, Denis B.

Publication type:

Article

Analysis of residue–residue interactions in the structures of ASIC1a suggests possible gating mechanisms.

Published in:

European Biophysics Journal, 2023, v. 52, n. 1/2, p. 111, doi. 10.1007/s00249-023-01628-1

By:

Korkosh, Vyacheslav S.;
Tikhonov, Denis B.

Publication type:

Article

Structural modeling of calcium binding in the selectivity filter of the L-type calcium channel.

Published in:

European Biophysics Journal, 2010, v. 39, n. 5, p. 839, doi. 10.1007/s00249-009-0574-2

By:

Cheng, Ricky C. K.;
Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Dual Mechanisms of the Diazepine-Benzimidazole Derivative, DAB-19, in Modulating Glutamatergic Neurotransmission.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5299, doi. 10.3390/ijms26115299

By:

Nikolaev, Maxim V.;
Fedorova, Irina M.;
Chistyakova, Oxana V.;
Postnikova, Tatiana Yu.;
Kim, Kira Kh.;
Dron, Mikhail Yu.;
Zaitsev, Aleksey V.;
Tikhonov, Denis B.

Publication type:

Article

Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00880

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models.

Published in:

Membranes, 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/membranes12020229

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Intersegment contacts determine geometry of the open and closed states in P-loop channels.

Published in:

Journal of Biomolecular Structure & Dynamics, 2020, v. 38, n. 4, p. 1012, doi. 10.1080/07391102.2019.1592026

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA.

Published in:

Marine Drugs, 2019, v. 17, n. 9, p. 510, doi. 10.3390/md17090510

By:

Finol-Urdaneta, Rocio K.;
McArthur, Jeffrey R.;
Korkosh, Vyacheslav S.;
Huang, Sun;
McMaster, Denis;
Glavica, Robert;
Tikhonov, Denis B.;
Zhorov, Boris S.;
French, Robert J.

Publication type:

Article

ω-Tbo-IT1-New Inhibitor of Insect Calcium Channels Isolated from Spider Venom.

Published in:

Scientific Reports, 2015, p. 17232, doi. 10.1038/srep17232

By:

Mikov, Alexander N.;
Fedorova, Irina M.;
Potapieva, Natalia N.;
Maleeva, Ekaterina E.;
Andreev, Yaroslav A.;
Zaitsev, Alexey V.;
Kim, Kira K.;
Bocharov, Eduard V.;
Bozin, Timur N.;
Altukhov, Dmitry A.;
Lipkin, Alexey V.;
Kozlov, Sergey A.;
Tikhonov, Denis B.;
Grishin, Eugene V.

Publication type:

Article

Non-classical mechanism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor channel block by fluoxetine.

Published in:

European Journal of Neuroscience, 2015, v. 41, n. 7, p. 867, doi. 10.1111/ejn.12817

By:

Barygin, Oleg I.;
Komarova, Margarita S.;
Tikhonova, Tatiana B.;
Tikhonov, Denis B.

Publication type:

Article

Conservation and variability of the pore-lining helices in P-loop channels.

Published in:

Channels (19336950), 2017, v. 11, n. 6, p. 660, doi. 10.1080/19336950.2017.1395536

By:

Tikhonov, Denis B.;
Zhorov, Boris S.

Publication type:

Article

Complex action of tyramine, tryptamine and histamine on native and recombinant ASICs.

Published in:

Channels (19336950), 2017, v. 11, n. 6, p. 648, doi. 10.1080/19336950.2017.1394557

By:

Barygin, Oleg I.;
Komarova, Margarita S.;
Tikhonova, Tatyana B.;
Korosteleva, Anastasiia S.;
Nikolaev, Maxim V.;
Magazanik, Lev G.;
Tikhonov, Denis B.

Publication type:

Article