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Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31596-7
By:
- Fu, Yongyao;
- Pajulas, Abigail;
- Wang, Jocelyn;
- Zhou, Baohua;
- Cannon, Anthony;
- Cheung, Cherry Cheuk Lam;
- Zhang, Jilu;
- Zhou, Huaxin;
- Fisher, Amanda Jo;
- Omstead, David T.;
- Khan, Sabrina;
- Han, Lei;
- Renauld, Jean-Christophe;
- Paczesny, Sophie;
- Gao, Hongyu;
- Liu, Yunlong;
- Yang, Lei;
- Tighe, Robert M.;
- Licona-Limón, Paula;
- Flavell, Richard A.
Publication type:
Article
TLR5 participates in the TLR4 receptor complex and promotes MyD88- dependent signaling in environmental lung injury.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.50458
By:
- Hussain, Salik;
- Johnson, Collin G.;
- Sciurba, Joseph;
- Meng, Xianglin;
- Stober, Vandy P.;
- Liu, Caini;
- Cyphert-Daly, Jaime M.;
- Bulek, Katarzyna;
- Qian, Wen;
- Solis, Alma;
- Sakamachi, Yosuke;
- Trempus, Carol S.;
- Aloor, Jim J.;
- Gowdy, Kym M.;
- Foster, W Michael;
- Hollingsworth, John W.;
- Tighe, Robert M.;
- Li, Xiaoxia;
- Fessler, Michael B.;
- Garantziotis, Stavros
Publication type:
Article
Uncovering the Epidemiology of Idiopathic Pulmonary Fibrosis in the Veterans Affairs Health System.
Published in:
2022
By:
- Tighe, Robert M.;
- Chaudhary, Sachin
Publication type:
Editorial
<sup>129</sup>Xenon Gas Exchange Magnetic Resonance Imaging as a Potential Prognostic Marker for Progression of Idiopathic Pulmonary Fibrosis.
Published in:
2020
By:
- Rankine, Leith J.;
- Ziyi Wang;
- Wang, Jennifer M.;
- Mu He;
- McAdams, H. Page;
- Mammarappallil, Joseph;
- Rackley, Craig R.;
- Driehuys, Bastiaan;
- Tighe, Robert M.;
- Wang, Ziyi;
- He, Mu
Publication type:
Letter
Autoreactive B cells recruited to lungs by silica exposure contribute to local autoantibody production in autoimmune-prone BXSB and B cell receptor transgenic mice.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.933360
By:
- Fee, Lanette;
- Kumar, Advika;
- Tighe, Robert M.;
- Foster, Mary H.
Publication type:
Article
Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease.
Published in:
2022
By:
- Ihrie, Mark D.;
- McQuade, Victoria L.;
- Womble, Jack T.;
- Hegde, Akhil;
- McCravy, Matthew S.;
- Lacuesta, Cyrus Victor G.;
- Tighe, Robert M.;
- Que, Loretta G.;
- Walker, Julia K. L.;
- Ingram, Jennifer L.
Publication type:
journal article
Genes of Innate Immunity and the Biological Response to Inhaled Ozone.
Published in:
Journal of Biochemical & Molecular Toxicology, 2013, v. 27, n. 1, p. 3, doi. 10.1002/jbt.21453
By:
- Li, Zhuowei;
- Tighe, Robert M.;
- Feng, Feifei;
- Ledford, Julie G.;
- Hollingsworth, John W.
Publication type:
Article
Management of Idiopathic Pulmonary Fibrosis.
Published in:
2019
By:
- Pleasants, Roy;
- Tighe, Robert M.
Publication type:
journal article
Role of Innate Immune System in Environmental Lung Diseases.
Published in:
Current Allergy & Asthma Reports, 2021, v. 21, n. 5, p. 1, doi. 10.1007/s11882-021-01011-0
By:
- Guttenberg, Marissa A.;
- Vose, Aaron T.;
- Tighe, Robert M.
Publication type:
Article
What Is "Normal" When Examining Myeloid Cells in Human Airways?
Published in:
2021
By:
- Novak, Caymen M.;
- Tighe, Robert M.;
- Ballinger, Megan N.
Publication type:
Editorial
Life at the Editorial "COVID Frontline". The American Thoracic Society Journal Family.
Published in:
2020
By:
- Chotirmall, Sanjay H.;
- Martinez, Fernando J.;
- Schumacker, Paul T.;
- Cooke, Colin R.;
- Seam, Nitin;
- Brochard, Laurent;
- Tighe, Robert M.;
- Levy, Bruce D.;
- Wedzicha, Jadwiga A.;
- Gern, Diane
Publication type:
Editorial
Know Where You Are: Pulmonary Macrophage Locations in the Human Lung.
Published in:
2020
By:
- Tighe, Robert M.;
- Yen Rei Yu;
- Yu, Yen Rei
Publication type:
Editorial
Silica Exposure Differentially Modulates Autoimmunity in Lupus Strains and Autoantibody Transgenic Mice.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02336
By:
- Foster, Mary H.;
- Ord, Jeffrey R.;
- Zhao, Emma J.;
- Birukova, Anastasiya;
- Fee, Lanette;
- Korte, Francesca M.;
- Asfaw, Yohannes G.;
- Roggli, Victor L.;
- Ghio, Andrew J.;
- Tighe, Robert M.;
- Clark, Amy G.
Publication type:
Article
Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study.
Published in:
PLoS ONE, 2021, v. 16, n. 3, p. 1, doi. 10.1371/journal.pone.0247316
By:
- Bedoya, Armando;
- Pleasants, Roy A.;
- Boggan, Joel C.;
- Seaman, Danielle;
- Reihman, Anne;
- Howard, Lauren;
- Kundich, Robert;
- Welty-Wolf, Karen;
- Tighe, Robert M.
Publication type:
Article
Genetic variation in surfactant protein-A2 alters responses to ozone.
Published in:
PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0247504
By:
- Pederson, William P.;
- Cyphert-Daly, Jaime M.;
- Tighe, Robert M.;
- Que, Loretta G.;
- Ledford, Julie G.
Publication type:
Article
Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains.
Published in:
Environmental Health Perspectives, 2020, v. 128, n. 11, p. 117009-1, doi. 10.1289/EHP7255
By:
- Wagner, James G.;
- Barkauskas, Christina E.;
- Vose, Aaron;
- Lewandowski, Ryan P.;
- Harkema, Jack R.;
- Tighe, Robert M.
Publication type:
Article
Biocidal products: Opportunities in risk assessment, management, and communication.
Published in:
Risk Analysis: An International Journal, 2024, v. 44, n. 2, p. 493, doi. 10.1111/risa.14160
By:
- Lee, Byung‐Mu;
- Bearth, Angela;
- Tighe, Robert M.;
- Kim, Manho;
- Tan, Simon;
- Kwon, Seok
Publication type:
Article
Tissue-Resident Alveolar Macrophages Reduce Ozone-induced Inflammation via MerTK-mediated Efferocytosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 6, p. 493, doi. 10.1165/rcmb.2023-0390OC
By:
- Guttenberg, Marissa A.;
- Vose, Aaron T.;
- Birukova, Anastasiya;
- Lewars, Kaitlyn;
- Cumming, R. Ian;
- Albright, Michaela C.;
- Mark, Jasper I.;
- Salazar, Claudia J.;
- Swaminathan, Suchitra;
- Yu, Zhan;
- Sokolenko, Yuliana V.;
- Bunyan, Elsie;
- Yaeger, Michael J.;
- Fessler, Michael B.;
- Que, Loretta G.;
- Gowdy, Kymberly M.;
- Misharin, Alexander V.;
- Tighe, Robert M.
Publication type:
Article
Human Immunodeficiency Virus, Smoking, and Chronic Obstructive Pulmonary Disease: A Case of T Cells Stuck in the Wrong Place?
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2021, v. 65, n. 5, p. 464, doi. 10.1165/rcmb.2021-0295ED
By:
- Tighe, Robert M.;
- Patel, Sweta M.
Publication type:
Article
Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 6, p. 698, doi. 10.1165/rcmb.2020-0007OC
By:
- Reece, Sky W.;
- Varikuti, Sanjay;
- Kilburg-Basnyat, Brita;
- Dunigan-Russell, Katelyn;
- Hodge, Myles X.;
- Luo, Bin;
- Madenspacher, Jennifer H.;
- Thomas, Seddon Y.;
- Tokarz, Debra A.;
- Tighe, Robert M.;
- Cook, Donald N.;
- Fessler, Michael B.;
- Gowdy, Kymberly M.
Publication type:
Article
Ozone Responses and Diet: Does Sex Determine the Relationship?
Published in:
2020
By:
- Tighe, Robert M.;
- Vose, Aaron
Publication type:
Editorial
Improving the Quality and Reproducibility of Flow Cytometry in the Lung: An Official American Thoracic Society Workshop Report.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 2, p. 150, doi. 10.1165/rcmb.2019-0191ST
By:
- Tighe, Robert M.;
- Redente, Elizabeth F.;
- Yen-Rei Yu;
- Herold, Susanne;
- Sperling, Anne I.;
- Curtis, Jeffrey L.;
- Duggan, Ryan;
- Swaminathan, Suchitra;
- Hideki Nakano;
- Zacharias, William J.;
- Janssen, William J.;
- Freeman, Christine M.;
- Brinkman, Ryan R.;
- Singer, Benjamin D.;
- Jakubzick, Claudia V.;
- Misharin, Alexander V.
Publication type:
Article
Euthanasia- and Lavage-mediated Effects on Bronchoalveolar Measures of Lung Injury and Inflammation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 59, n. 2, p. 257, doi. 10.1165/rcmb.2017-0357OC
By:
- Tighe, Robert M.;
- Birukova, Anastasiya;
- Yaeger, Michael J.;
- Reece, Sky W.;
- Gowdy, Kymberly M.
Publication type:
Article
Inflammation Gets on the Lung's Nerves: IL-17 and Neuroendocrine Cells Mediate Ozone Responses in Obesity.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 58, n. 3, p. 284, doi. 10.1165/rcmb.2017-0363ed
By:
- Garantziotis, Stavros;
- Tighe, Robert M.
Publication type:
Article
Flow Cytometric Analysis of Immune Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 1, p. E1
By:
- Yen-Rei A. Yu;
- Hotten, Danielle F.;
- Malakhau, Yuryi;
- Volker, Ellen;
- Ghio, Andrew J.;
- Noble, Paul W.;
- Kraft, Monica;
- Hollingsworth, John W.;
- Gunn, Michael D.;
- Tighe, Robert M.
Publication type:
Article
Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 1, p. 13, doi. 10.1165/rcmb.2015-0146OC
By:
- Yen-Rei A. Yu;
- Hotten, Danielle F.;
- Yuryi Malakhau;
- Volker, Ellen;
- Ghio, Andrew J.;
- Noble, Paul W.;
- Kraft, Monica;
- Hollingsworth, John W.;
- Gunn, Michael D.;
- Tighe, Robert M.
Publication type:
Article
Identification of Myeloid Cell Subsets in Murine Lungs Using Flow Cytometry.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 2, p. 180, doi. 10.1165/rcmb.2012-0366MA
By:
- Zaynagetdinov, Rinat;
- Sherrill, Taylor P.;
- Kendall, Peggy L.;
- Segal, Brahm H.;
- Weller, Kevin P.;
- Tighe, Robert M.;
- Blackwell, Timothy S.
Publication type:
Article
Recruited Exudative Macrophages Selectively Produce CXCL10 Following Noninfectious Lung Injury.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 4, p. 781, doi. 10.1165/rcmb.2010-0471OC
By:
- Tighe, Robert M.;
- Liang, Jiurong;
- Liu, Ningshan;
- Jung, Yoosun;
- Jiang, Dianhua;
- Gunn, Michael D.;
- Noble, Paul W.
Publication type:
Article
Maternal exposure to ultrafine particles enhances influenza infection during pregnancy.
Published in:
Particle & Fibre Toxicology, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12989-023-00521-1
By:
- Drury, Nicholas L.;
- Mustapha, Toriq;
- Shore, Ross A.;
- Zhao, Jiayun;
- Wright, Gus A.;
- Hoffmann, Aline Rodrigues;
- Talcott, Susanne U.;
- Regan, Annette;
- Tighe, Robert M.;
- Zhang, Renyi;
- Johnson, Natalie M.
Publication type:
Article
Lung-gut axis of microbiome alterations following co-exposure to ultrafine carbon black and ozone.
Published in:
Particle & Fibre Toxicology, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12989-023-00528-8
By:
- Mazumder, Md Habibul Hasan;
- Gandhi, Jasleen;
- Majumder, Nairrita;
- Wang, Lei;
- Cumming, Robert Ian;
- Stradtman, Sydney;
- Velayutham, Murugesan;
- Hathaway, Quincy A.;
- Shannahan, Jonathan;
- Hu, Gangqing;
- Nurkiewicz, Timothy R.;
- Tighe, Robert M.;
- Kelley, Eric E.;
- Hussain, Salik
Publication type:
Article
Lethal eosinophilic crystalline pneumonia in mice expressing a stabilized Csf2 mRNA.
Published in:
FASEB Journal, 2023, v. 37, n. 8, p. e23100, doi. 10.1096/fj.202300757R
By:
- Yukitomo Arao;
- Stumpo, Deborah J.;
- Hoenerhoff, Mark J.;
- Tighe, Robert M.;
- Yen-Rei Yu;
- Sutton, Deloris;
- Kashyap, Amogh;
- Beerman, Isabel;
- Blackshear, Perry J.
Publication type:
Article
An IL-9–pulmonary macrophage axis defines the allergic lung inflammatory environment.
Published in:
Science Immunology, 2022, v. 7, n. 68, p. 1, doi. 10.1126/sciimmunol.abi9768
By:
- Yongyao Fu;
- Jocelyn Wang;
- Baohua Zhou;
- Pajulas, Abigail;
- Hongyu Gao;
- Ramdas, Baskar;
- Byunghee Koh;
- Ulrich, Benjamin J.;
- Shuangshuang Yang;
- Kapur, Reuben;
- Renauld, Jean-Christophe;
- Paczesny, Sophie;
- Yunlong Liu;
- Tighe, Robert M.;
- Licona-Limón, Paula;
- Flavell, Richard A.;
- Shogo Takatsuka;
- Daisuke Kitamura;
- Tepper, Robert S.;
- Jie Sun
Publication type:
Article
The Opprobrium of Big Tobacco.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 9, p. 1030, doi. 10.1164/ajrccm.185.9.1030
By:
- PIANTADOSI, CLAUDE A.;
- BARTZ, RAQUEL R.;
- CARRAWAY, MARTHA S.;
- GHIO, ANDREW J.;
- MCMAHON, TIMOTHY J.;
- MURDOCH, DAVID M.;
- ROGGLI, VICTOR L.;
- SHOFER, SCOTT L.;
- TIGHE, ROBERT M.;
- WELTY-WOLF, KAREN E.;
- YOUNG, STEPHEN L.
Publication type:
Article
Effect of the <italic>S</italic>‐nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma.
Published in:
Immunity, Inflammation & Disease, 2018, v. 6, n. 2, p. 322, doi. 10.1002/iid3.220
By:
- Que, Loretta G.;
- Yang, Zhonghui;
- Lugogo, Njira L.;
- Katial, Rohit K.;
- Shoemaker, Steven A.;
- Troha, Janice M.;
- Rodman, David M.;
- Tighe, Robert M.;
- Kraft, Monica
Publication type:
Article
Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159329
By:
- Pinilla-Vera, Miguel;
- Xiong, Zeyu;
- Zhao, Yutong;
- Zhao, Jing;
- Donahoe, Michael P.;
- Barge, Suchitra;
- Horne, William T.;
- Kolls, Jay K.;
- McVerry, Bryan J.;
- Birukova, Anastasiya;
- Tighe, Robert M.;
- Foster, W. Michael;
- Hollingsworth, John;
- Ray, Anuradha;
- Mallampalli, Rama;
- Ray, Prabir;
- Lee, Janet S.
Publication type:
Article
Linking Adiposity to Interstitial Lung Disease: The Role of the Dysfunctional Adipocyte and Inflammation.
Published in:
Cells (2073-4409), 2023, v. 12, n. 18, p. 2206, doi. 10.3390/cells12182206
By:
- Macklin, Michael;
- Thompson, Chelsea;
- Kawano-Dourado, Leticia;
- Bauer Ventura, Iazsmin;
- Weschenfelder, Camila;
- Trostchansky, Andrés;
- Marcadenti, Aline;
- Tighe, Robert M.
Publication type:
Article
Vertical sleeve gastrectomy associates with airway hyperresponsiveness in a murine model of allergic airway disease and obesity.
Published in:
Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1092277
By:
- Womble, Jack T.;
- Ihrie, Mark D.;
- McQuade, Victoria L.;
- Hegde, Akhil;
- McCravy, Matthew S.;
- Phatak, Sanat;
- Tighe, Robert M.;
- Que, Loretta G.;
- D’Alessio, David;
- Walker, Julia K. L.;
- Ingram, Jennifer L.
Publication type:
Article
The Eyes Have It—for Idiopathic Pulmonary Fibrosis: a Preliminary Observation.
Published in:
Pulmonary Therapy, 2022, v. 8, n. 3, p. 327, doi. 10.1007/s41030-022-00198-5
By:
- Pleasants, Roy A.;
- Bedoya, Armando D.;
- Boggan, Joel M.;
- Welty-Wolf, Karen;
- Tighe, Robert M.
Publication type:
Article
ATS Core Curriculum 2015. Part I: Adult Pulmonary Medicine.
Published in:
2015
By:
- Michaud, Gaëtane C.;
- Channick, Colleen L.;
- Marion, Chad R.;
- Tighe, Robert M.;
- Town, James A.;
- Luks, Andrew M.;
- Richards, Jeremy B.;
- Kher, Sucharita;
- Mota, Prerna;
- Gina Hong;
- West, Natalie E.;
- Rackley, Craig;
- Neilans, Luke;
- Rodriguez-Lopez, Josanna;
- DuBrock, Hilary;
- Kennedy, Cassie C.;
- Kelm, Diana J.;
- Thomson, Carey C.;
- Hong, Gina
Publication type:
journal article
Altered ontogeny and transcriptomic signatures of tissue-resident pulmonary interstitial macrophages ameliorate allergic airway hyperresponsiveness.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1371764
By:
- Tighe, Robert M.;
- Birukova, Anastasiya;
- Malakhau, Yuryi;
- Yoshihiko Kobayashi;
- Vose, Aaron T.;
- Chandramohan, Vidya;
- Cyphert-Daly, Jaime M.;
- Cumming, R. Ian;
- Kirshner, Helene Fradin;
- Tata, Purushothama R.;
- Ingram, Jennifer L.;
- Gunn, Michael D.;
- Que, Loretta G.;
- Yu, Yen-Rei A.
Publication type:
Article
Novel Mechanisms of Ozone-Induced Pulmonary Inflammation and Resolution, and the Potential Protective Role of Scavenger Receptor BI.
Published in:
Research Report / HEI, 2021, n. 204, p. i
By:
- Gowdy, Kymberly M.;
- Kilburg-Basnyat, Brita;
- Hodge, Myles X.;
- Reece, Sky W.;
- Yermalitsky, Valery;
- Davies, Sean S.;
- Manke, Jonathan;
- Armstrong, Michael L.;
- Reisdorph, Nichole;
- Tighe, Robert M.;
- Shaikh, S. Raza
Publication type:
Article
Air pollution and respiratory infections: the past, present, and future.
Published in:
Toxicological Sciences, 2023, v. 192, n. 1, p. 3, doi. 10.1093/toxsci/kfad003
By:
- Monoson, Alexys;
- Schott, Evangeline;
- Ard, Kerry;
- Kilburg-Basnyat, Brita;
- Tighe, Robert M;
- Pannu, Sonal;
- Gowdy, Kymberly M
Publication type:
Article
Sex Differences in Pulmonary Eicosanoids and Specialized Pro-Resolving Mediators in Response to Ozone Exposure.
Published in:
Toxicological Sciences, 2021, v. 183, n. 1, p. 170, doi. 10.1093/toxsci/kfab081
By:
- Yaeger, Michael J;
- Reece, Sky W;
- Kilburg-Basnyat, Brita;
- Hodge, Miles X;
- Pal, Anandita;
- Dunigan-Russell, Katelyn;
- Luo, Bin;
- You, Dorothy J;
- Bonner, James C;
- Spangenburg, Espen E;
- Tokarz, Debra;
- Hannan, Johanna;
- Armstrong, Michael;
- Manke, Jonathan;
- Reisdorph, Nichole;
- Tighe, Robert M;
- Shaikh, S Raza;
- Gowdy, Kymberly M
Publication type:
Article
Sex Modifies Acute Ozone-Mediated Airway Physiologic Responses.
Published in:
Toxicological Sciences, 2019, v. 169, n. 2, p. 499, doi. 10.1093/toxsci/kfz056
By:
- Birukova, Anastasiya;
- Cyphert-Daly, Jaime;
- Cumming, Robert Ian;
- Yu, Yen-Rei;
- Gowdy, Kymberly M;
- Que, Loretta G;
- Tighe, Robert M
Publication type:
Article

Found: 44